Natriuretic peptides block synaptic transmission by activating phosphodiesterase 2A and reducing presynaptic PKA activity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 43, 2012, Pages 17681-17686

  Hu, Fei ^a,b   Ren, Jing ^b,c   Zhang, Ju En ^b,d   Zhong, Weixin ^b   Luo, Minmin ^a,b,d  

^a GRADUATE SCHOOL OF PEKING UNION MEDICAL COLLEGE   (China)

^b NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES   (China)

^c BEIJING NORMAL UNIVERSITY   (China)

^d TSINGHUA UNIVERSITY   (China)

Author keywords

ChannelRhodopsin 2; Neurotransmission; Presynaptic modulator

Indexed keywords

ATRIAL NATRIURETIC FACTOR; BRAIN NATRIURETIC PEPTIDE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC GMP; CYCLIC GMP DEPENDENT PROTEIN KINASE; GLUTAMIC ACID; KT 5823; PHOSPHODIESTERASE; PHOSPHODIESTERASE 2A; UNCLASSIFIED DRUG;

ANALGESIA; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; ENZYME ACTIVATION; ENZYME ACTIVITY; EXCITATORY POSTSYNAPTIC POTENTIAL; HABENULA; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYNAPTIC TRANSMISSION;

ANIMALS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 2; FEMALE; MALE; MICE; MICE, INBRED C57BL; NATRIURETIC PEPTIDES; PRESYNAPTIC TERMINALS; SYNAPTIC TRANSMISSION;

EID: 84867905108     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1209185109     Document Type: Article

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