Genomic regions associated with bovine milk fatty acids in both summer and winter milk samples

BMC Genetics

Volumn 13, Issue , 2012, Pages

  Bouwman, Aniek C ^a   Visker, Marleen H P W ^a   van Arendonk, Johan A M ^a   Bovenhuis, Henk ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Dairy; Genome wide association; Milk fatty acids

Indexed keywords

FATTY ACID; MILK FAT;

ARTICLE; CONTROLLED STUDY; GENETIC ASSOCIATION; GENETIC TRAIT; GENOMICS; HERD; HERITABILITY; MILK; NONHUMAN; PHENOTYPE; SINGLE NUCLEOTIDE POLYMORPHISM; SUMMER; WINTER;

ANIMALS; CATTLE; FATTY ACIDS; GENOME; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; MILK; PHENOTYPE; POLYMORPHISM, SINGLE NUCLEOTIDE; SEASONS;

BOVINAE;

EID: 84867894980     PISSN: None     EISSN: 14712156     Source Type: Journal    
DOI: 10.1186/1471-2156-13-93     Document Type: Article

References (27)

1. Schennink A, Stoop WM, Visker MHPW, Heck JML, Bovenhuis H, Van Der Poel JJ, Van Valenberg HJF, Van Arendonk JAM. DGAT1 underlies large genetic variation in milk-fat composition of dairy cows. Anim Genet 2007, 38(5):467-473. 10.1111/j.1365-2052.2007.01635.x, 17894561.
2. Bouwman A, Bovenhuis H, Visker M, Van Arendonk J. Genome-wide association of milk fatty acids in Dutch dairy cattle. BMC Genet 2011, 12(1):43. 3120725, 21569316.
3. Chanock SJ, Manolio T, Boehnke M, Boerwinkle E, Hunter DJ, Thomas G, Hirschhorn JN, Goncalo A, Altshuler D, Bailey-Wilson JE, et al. Replicating genotype-phenotype associations. Nature 2007, 447(7145):655-660. 10.1038/447655a, 17554299.
4. van den Oord EJCG. Controlling false discoveries in genetic studies. Am J Med Genet 2008, 147B(5):637-644. 10.1002/ajmg.b.30650, 18092307.
5. Stoop WM, van Arendonk JAM, Heck JML, van Valenberg HJF, Bovenhuis H. Genetic Parameters for Major Milk Fatty Acids and Milk Production Traits of Dutch Holstein-Friesians. J Dairy Sci 2008, 91(1):385-394. 10.3168/jds.2007-0181, 18096963.
6. Gilmour AR, Gogel BJ, Cullis BR, Thompson R. ASReml User Guide Release 2.0 Hemel Hempstead, HP1 1ES 2006, VSN International Ltd, UK.
7. Liu Y, Qin X, Song X-Z, Jiang H, Shen Y, Durbin KJ, Lien S, Kent M, Sodeland M, Ren Y, et al. Bos taurus genome assembly. BMC Genomics 2009, 10(1):180. 10.1186/1471-2164-10-180, 2686734, 19393050.
8. Storey JD, Tibshirani R. Statistical significance for genomewide studies. Proc Natl Acad Sci 2003, 100(16):9440-9445. 10.1073/pnas.1530509100, 170937, 12883005.
9. Beavis WD. QTL analyses: power precision and accuracy. Molecular dissection of complex traits 1998, 145-162. CRC Press, New York, AH P.
10. Liu Y-J, Papasian CJ, Liu J-F, Hamilton J, Deng H-W. Is Replication the Gold Standard for Validating Genome-Wide Association Findings?. PLoS One 2008, 3(12):e4037. 10.1371/journal.pone.0004037, 2605260, 19112512.
11. Zimin A, Delcher A, Florea L, Kelley D, Schatz M, Puiu D, Hanrahan F, Pertea G, Van Tassell C, Sonstegard T, et al. A whole-genome assembly of the domestic cow, Bos taurus. Genome Biology 2009, 10(4):R42. 10.1186/gb-2009-10-4-r42, 2688933, 19393038.
12. Bionaz M, Loor J. Gene networks driving bovine milk fat synthesis during the lactation cycle. BMC Genomics 2008, 9(1):366. 10.1186/1471-2164-9-366, 2547860, 18671863.
13. Fievez V, Vlaeminck B, Dhanoa MS, Dewhurst RJ. Use of Principal Component Analysis to Investigate the Origin of Heptadecenoic and Conjugated Linoleic Acids in Milk. J Dairy Sci 2003, 86(12):4047-4053. 10.3168/jds.S0022-0302(03)74016-8, 14740843.
14. Smith S, Witkowski A, Joshi AK. Structural and functional organization of the animal fatty acid synthase. Prog Lipid Res 2003, 42(4):289-317. 10.1016/S0163-7827(02)00067-X, 12689621.
15. Duchemin S, Bovenhuis H, Stoop WM, Bouwman AC, Van Arendonk JAM, Visker MHPW. Genetic correlation between composition of bovine milk fat in winter and summer, and DGAT1 and SCD1 by season interactions. J Dairy Sci 2012, in press.
16. Conte G, Mele M, Chessa S, Castiglioni B, Serra A, Pagnacco G, Secchiari P. Diacylglycerol acyltransferase 1, stearoyl-CoA desaturase 1, and sterol regulatory element binding protein 1 gene polymorphisms and milk fatty acid composition in Italian Brown cattle. J Dairy Sci 2010, 93(2):753-763. 10.3168/jds.2009-2581, 20105547.
17. Grisart B, Coppieters W, Farnir F, Karim L, Ford C, Berzi P, Cambisano N, Mni M, Reid S, Simon P, et al. Positional Candidate Cloning of a QTL in Dairy Cattle: Identification of a Missense Mutation in the Bovine DGAT1 Gene with Major Effect on Milk Yield and Composition. Genome Res 2002, 12(2):222-231. 10.1101/gr.224202, 11827942.
18. Morris C, Cullen N, Glass B, Hyndman D, Manley T, Hickey S, McEwan J, Pitchford W, Bottema C, Lee M. Fatty acid synthase effects on bovine adipose fat and milk fat. Mamm Genome 2007, 18(1):64-74. 10.1007/s00335-006-0102-y, 17242864.
19. Schennink A, Bovenhuis H, Léon-Kloosterziel KM, Van Arendonk JAM, Visker MHPW. Effect of polymorphisms in the FASN, OLR1, PPARGC1A, PRL and STAT5A genes on bovine milk-fat composition. Anim Genet 2009, 40(6):909-916. 10.1111/j.1365-2052.2009.01940.x, 19719788.
20. Stoop WM, Schennink A, Visker MHPW, Mullaart E, van Arendonk JAM, Bovenhuis H. Genome-wide scan for bovine milk-fat composition. I. Quantitative trait loci for short- and medium-chain fatty acids. J Dairy Sci 2009, 92(9):4664-4675. 10.3168/jds.2008-1966, 19700730.
21. Kgwatalala PM, Ibeagha-Awemu EM, Hayes JF, Zhao X. Stearoyl-CoA desaturase 1 3′UTR SNPs and their influence on milk fatty acid composition of Canadian Holstein cows. J Anim Breed Genet 2009, 126(5):394-403. 10.1111/j.1439-0388.2008.00796.x, 19765166.
22. Mele M, Conte G, Castiglioni B, Chessa S, Macciotta NPP, Serra A, Buccioni A, Pagnacco G, Secchiari P. Stearoyl-Coenzyme A Desaturase Gene Polymorphism and Milk Fatty Acid Composition in Italian Holsteins. J Dairy Sci 2007, 90(9):4458-4465. 10.3168/jds.2006-617, 17699067.
23. Moioli B, Contarini G, Avalli A, Catillo G, Orrù L, De Matteis G, Masoero G, Napolitano F. Short Communication: Effect of Stearoyl-Coenzyme A Desaturase Polymorphism on Fatty Acid Composition of Milk. J Dairy Sci 2007, 90(7):3553-3558. 10.3168/jds.2006-855, 17582140.
24. Schennink A, Heck JML, Bovenhuis H, Visker MHPW, van Valenberg HJF, van Arendonk JAM. Milk Fatty Acid Unsaturation: Genetic Parameters and Effects of Stearoyl-CoA Desaturase (SCD1) and Acyl CoA: Diacylglycerol Acyltransferase 1 (DGAT1). J Dairy Sci 2008, 91(5):2135-2143. 10.3168/jds.2007-0825, 18420645.
25. Wibowo T, Gaskins C, Newberry R, Thorgaard G, Michal J, Jiang Z. Genome Assembly Anchored QTL Map of Bovine Chromosome 14. Int J Biol Sci 2008, 4(6):406-414. 2586679, 19043607.
26. Igl BW, König IR, Ziegler A. What Do We Mean by 'Replication' and 'Validation' in Genome-Wide Association Studies?. Hum Hered 2009, 67(1):66-68. 10.1159/000164400, 18931511.
27. König IR. Validation in Genetic Association Studies. Brief Bioinform 2011, 12(3):253-258. 10.1093/bib/bbq074, 21546448.