Milk fatty acid unsaturation: Genetic parameters and effects of stearoyl-CoA desaturase (SCD1) and Acyl CoA: Diacylglycerol acyltransferase 1 (DGAT1)

Journal of Dairy Science

Volumn 91, Issue 5, 2008, Pages 2135-2143

  Schennink, A ^a   Heck, J M L ^a   Bovenhuis, H ^a   Visker, M H P W ^a   Van Valenberg, H J F ^a   Van Arendonk, J A M ^a  

^a WAGENINGEN UNIVERSITY   (Netherlands)

Author keywords

Dairy cow; DGAT1; Milk fatty acid composition; SCD1

Indexed keywords

BOS; FRIESIA;

EID: 44349192050     PISSN: 00220302     EISSN: 15253198     Source Type: Journal    
DOI: 10.3168/jds.2007-0825     Document Type: Article

References (33)

1. L.H. Baumgard B.A. Corl D.A. Dwyer A. Saebo D.E. Bauman Identification of the conjugated linoleic acid isomer that inhibits milk fat synthesis Am. J. Physiol. Regul. Integr. Comp. Physiol. 278 2000 R179 R184
2. A.D. Beaulieu D.L. Palmquist Differential effects of high fat diets on fatty acid composition in milk of Jersey and Holstein cows J. Dairy Sci. 78 1995 1336 1344
3. M. Chung S. Ha S. Jeong J. Bok K. Cho M. Baik Y. Choi Cloning and characterization of bovine stearoyl CoA desaturasel cDNA from adipose tissues Biosci. Biotechnol. Biochem. 64 2000 1526 1530
4. E.J. DePeters J.F. Medrano B.A. Reed Fatty acid composition of milk fat from three breeds of dairy cattle Can. J. Anim. Sci. 75 1995 267 269
5. J.K. Drackley A.D. Beaulieu J.P. Elliott Responses of milk fat composition to dietary fat or nonstructural carbohydrates in Holstein and Jersey cows J. Dairy Sci. 84 2001 1231 1237
6. H.G. Enoch A. Catala P. Strittmatter Mechanism of rat liver microsomal stearyl-CoA desaturas. Studies of the substrate specificity, enzyme-substrate interactions, and the function of lipid J. Biol Chem. 251 1976 5095 5103
7. A.R. Gilmour B.J. Gogel B.R. Cullis S.J. Welham R. Thompson 1.0. VSN International Ltd. 2002 ASReml User Guide Release Hemel Hempstead, UK
8. B. Grisart W. Coppieters F. Farnir L. Karim C. Ford P. Berzi N. Cambisano M. Mni S. Reid P. Simon R. Spelman M. Georges R. Snell Positional candidate cloning of a QTL in dairy cattle: Identification of a missense mutation in the bovine DGAT1 gene with major effect on milk yield and composition Genome Res. 12 2002 222 231
9. B. Heringstad D. Gianola Y.M. Chang J. Odegard G. Klemetsdal Genetic associations between clinical mastitis and somatic cell score in early first-lactation cows J. Dairy Sci. 89 2006 2236 2244
10. R.G. Jensen The composition of bovine milk lipids: January 1995 to December 2000 J. Dairy Sci. 85 2002 295 350
11. J.A. Kelsey B.A. Corl R.J. Collier D.E. Bauman The effect of breed, parity, and stage of lactation on conjugated linoleic acid (CLA) in milk fat from dairy cows J. Dairy Sci. 86 2003 2588 2597
12. F. Lawless C. Stanton P. L’Escop R. Devery P. Dillon J.J. Murphy Influence of breed on bovine milk cis -9, trans -11-conjugated linoleic acid content Livest. Prod. Sci. 62 1999 43 49
13. A.J. Lengi B.A. Corl Identification and characterization of a novel bovine stearoyl-CoA desaturase isoform with homology to human SCD5 Lipids 42 2007 499 508
14. A.L. Lock P.C. Garnsworthy Independent effects of dietary linoleic and linolenic fatty acids on the conjugated linoleic acid content of cows’ milk Anim. Sci. 74 2002 163 176
15. A.L. Lock P.C. Garnsworthy Seasonal variation in milk conjugated linoleic acid and delta9-desaturase activity in dairy cows Livest. Prod. Sci. 79 2003 47 59
16. M. Mele G. Conte B. Castiglioni S. Chessa N.P. Macciotta A. Serra A. Buccioni G. Pagnacco P. Secchiari Stearoyl-coenzyme A desaturase gene polymorphism and milk fatty acid composition in Italian Holsteins J. Dairy Sci. 90 2007 4458 4465
17. R.P. Mensink P.L. Zock A.D.M. Kester M.B. Katan Effects of dietary fatty acids and carbohydrates on the ratio of serum total to HDL cholesterol and on serum lipids and apolipo-proteins: A meta-analysis of 60 controlled trials Am. J. Clin. Nutr. 77 2003 1146 1155
18. M. Miyazaki J.M. Ntambi Role of stearoyl-coenzyme A desaturase in lipid metabolism Prostaglandins Leukot. Essent. Fatty Acids 68 2003 113 121
19. B. Moioli G. Contarini A. Avalli G. Catillo L. Orru G. De Matteis G. Masoero F. Napolitano Short communication: Effect of stearoyl-coenzyme A desaturase polymorphism on fatty acid composition of milk J. Dairy Sci. 90 2007 3553 3558
20. E.E. Mosley M.A. McGuire Methodology for the in vivo measurement of the delta(9)-desaturation of myristic, palmitic, and stearic acids in lactating dairy cattle Lipids. 42 2007 939 945
21. S.L. Pereira A.E. Leonard P. Mukerji Recent advances in the study of fatty acid desaturases from animals and lower eukaryotes Prostaglandins Leukot. Essent. Fatty Acids. 68 2003 97 106
22. J.W. Perfield II P. Delmonte A.L. Lock M.P. Yurawecz D.E. Bauman Trans -10, trans -12 conjugated linoleic acid does not affect milk fat yield but reduces delta9-desaturase index in dairy cows J. Dairy Sci. 89 2006 2559 2566
23. J.W. Perfield II A.L. Lock J.M. Griinari A. Saebo P. Delmonte D.A. Dwyer D.E. Bauman Trans -9, cis -11 conjugated linoleic acid reduces milk fat synthesis in lactating dairy cows J. Dairy Sci. 90 2007 2211 2218
24. D.G. Peterson J.A. Kelsey D.E. Bauman Analysis of variation in cis -9, trans -11 conjugated linoleic acid (CLA) in milk fat of dairy cows J. Dairy Sci. 85 2002 2164 2172
25. M.D. Royal P.C. Garnsworthy Estimation of genetic variation in Δ9-desaturase enzyme activity in dairy cows Proc. Br. Soc. Anim. Sci., York, UK. Br. Soc. Anim. Sci., Penicuik, UK. 2005 Page 52
26. A. Schennink W.M. Stoop M.H.P.W. Visker J.M.L. Heck H. Bovenhuis J.J. van der Poel H.J.F. van Valenberg J.A.M. van Arendonk DGAT1 underlies large genetic variation in milk-fat composition of dairy cows Anim. Genet. 38 2007 467 473
27. J. Shanklin E. Whittle B.G. Fox Eight histidine residues are catalytically essential in a membrane-associated iron enzyme, stearoyl-CoA desaturase, and are conserved in alkane hydroxylase and xylene monooxygenase Biochemistry 33 1994 12787 12794
28. M. Sol Morales D.L. Palmquist W.P. Weiss Milk fat composition of Holstein and Jersey cows with control or depleted copper status and fed whole soybeans or tallow J. Dairy Sci. 83 2000 2112 2119
29. H. Soyeurt P. Dardenne A. Gillon C. Croquet S. Vanderick P. Mayeres C. Bertozzi N. Gengler Variation in fatty acid contents of milk and milk fat within and across breeds J. Dairy Sci. 89 2006 4858 4865
30. H. Soyeurt A. Gillon S. Vanderick P. Mayeres C. Bertozzi N. Gengler Estimation of heritability and genetic correlations for the major fatty acids in bovine milk J. Dairy Sci. 90 2007 4435 4442
31. W.M. Stoop J.A.M. Van Arendonk J.M.L. Heck H.J.F. Van Valenberg H. Bovenhuis Genetic parameters for major milk fatty acids and milk production traits of Dutch Holstein Friesians J. Dairy Sci. 91 2008 385 394
32. M. Taniguchi T. Utsugi K. Oyama H. Mannen M. Kobayashi Y. Tanabe A. Ogino S. Tsuji Genotype of stearoyl-CoA desaturase is associated with fatty acid composition in Japanese Black cattle Mamm. Genome 15 2004 142 148
33. J.B.M. Wilmink Adjustment of test-day milk, fat and protein yield for age, season and stage of lactation Livest. Prod. Sci. 16 1987 335 348