-
1
-
-
34648819975
-
Structural basis of the collagen-binding mode of discoidin domain receptor 2
-
Ichikawa O., Osawa M., Nishida N., Goshima N., Nomura N., Shimada I. Structural basis of the collagen-binding mode of discoidin domain receptor 2. Embo J. 2007, 26:4168-4176.
-
(2007)
Embo J.
, vol.26
, pp. 4168-4176
-
-
Ichikawa, O.1
Osawa, M.2
Nishida, N.3
Goshima, N.4
Nomura, N.5
Shimada, I.6
-
2
-
-
0031309902
-
The discoidin domain receptor tyrosine kinases are activated by collagen
-
Vogel W., Gish G.D., Alves F., Pawson T. The discoidin domain receptor tyrosine kinases are activated by collagen. Mol. Cell 1997, 1:13-23.
-
(1997)
Mol. Cell
, vol.1
, pp. 13-23
-
-
Vogel, W.1
Gish, G.D.2
Alves, F.3
Pawson, T.4
-
3
-
-
33646341752
-
Sensing extracellular matrix: an update on discoidin domain receptor function
-
Vogel W.F., Abdulhussein R., Ford C.E. Sensing extracellular matrix: an update on discoidin domain receptor function. Cell Signal. 2006, 18:1108-1116.
-
(2006)
Cell Signal.
, vol.18
, pp. 1108-1116
-
-
Vogel, W.F.1
Abdulhussein, R.2
Ford, C.E.3
-
4
-
-
33746831573
-
The discoidin domain receptor DDR2 is a receptor for type X collagen
-
Leitinger B., Kwan A.P. The discoidin domain receptor DDR2 is a receptor for type X collagen. Matrix Biol. 2006, 25:355-364.
-
(2006)
Matrix Biol.
, vol.25
, pp. 355-364
-
-
Leitinger, B.1
Kwan, A.P.2
-
5
-
-
0032921366
-
Discoidin domain receptors: Structural relations and functional implications
-
Vogel W. Discoidin domain receptors: Structural relations and functional implications. Faseb. J. 1999, (Suppl. 13):S77-82.
-
(1999)
Faseb. J.
, Issue.SUPPL. 13
-
-
Vogel, W.1
-
6
-
-
0037125948
-
Binding of discoidin domain receptor 2 to collagen I: an atomic force microscopy investigation
-
Agarwal G., Kovac L., Radziejewski C., Samuelsson S.J. Binding of discoidin domain receptor 2 to collagen I: an atomic force microscopy investigation. Biochemistry 2002, 41:11091-11098.
-
(2002)
Biochemistry
, vol.41
, pp. 11091-11098
-
-
Agarwal, G.1
Kovac, L.2
Radziejewski, C.3
Samuelsson, S.J.4
-
7
-
-
0031310941
-
An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors
-
Shrivastava A., Radziejewski C., Campbell E., Kovac L., McGlynn M., Ryan T.E., Davis S., Goldfarb M.P., Glass D.J., Lemke G., Yancopoulos G.D. An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors. Mol. Cell 1997, 1:25-34.
-
(1997)
Mol. Cell
, vol.1
, pp. 25-34
-
-
Shrivastava, A.1
Radziejewski, C.2
Campbell, E.3
Kovac, L.4
McGlynn, M.5
Ryan, T.E.6
Davis, S.7
Goldfarb, M.P.8
Glass, D.J.9
Lemke, G.10
Yancopoulos, G.D.11
-
8
-
-
8544270883
-
The D2 period of collagen II contains a specific binding site for the human discoidin domain receptor DDR2
-
Leitinger B., Steplewski A., Fertala A. The D2 period of collagen II contains a specific binding site for the human discoidin domain receptor DDR2. J. Mol. Biol. 2004, 344:993-1003.
-
(2004)
J. Mol. Biol.
, vol.344
, pp. 993-1003
-
-
Leitinger, B.1
Steplewski, A.2
Fertala, A.3
-
9
-
-
0035176409
-
Discoidin domain receptor (DDR) 1 and 2: collagen-activated tyrosine kinase receptors in the cornea
-
Mohan R.R., Wilson S.E. Discoidin domain receptor (DDR) 1 and 2: collagen-activated tyrosine kinase receptors in the cornea. Exp. Eye Res. 2001, 72:87-92.
-
(2001)
Exp. Eye Res.
, vol.72
, pp. 87-92
-
-
Mohan, R.R.1
Wilson, S.E.2
-
10
-
-
0028799694
-
Distinct structural characteristics of discoidin I subfamily receptor tyrosine kinases and complementary expression in human cancer
-
Alves F., Vogel W., Mossie K., Millauer B., Hofler H., Ullrich A. Distinct structural characteristics of discoidin I subfamily receptor tyrosine kinases and complementary expression in human cancer. Oncogene 1995, 10:609-618.
-
(1995)
Oncogene
, vol.10
, pp. 609-618
-
-
Alves, F.1
Vogel, W.2
Mossie, K.3
Millauer, B.4
Hofler, H.5
Ullrich, A.6
-
11
-
-
0034988084
-
The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism
-
Labrador J.P., Azcoitia V., Tuckermann J., Lin C., Olaso E., Manes S., Bruckner K., Goergen J.L., Lemke G., Yancopoulos G., Angel P., Martinez C., Klein R. The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism. EMBO Rep. 2001, 2:446-452.
-
(2001)
EMBO Rep.
, vol.2
, pp. 446-452
-
-
Labrador, J.P.1
Azcoitia, V.2
Tuckermann, J.3
Lin, C.4
Olaso, E.5
Manes, S.6
Bruckner, K.7
Goergen, J.L.8
Lemke, G.9
Yancopoulos, G.10
Angel, P.11
Martinez, C.12
Klein, R.13
-
12
-
-
48249091732
-
A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene DDR2 in the mouse
-
Kano K., Marin de Evsikova C., Young J., Wnek C., Maddatu T.P., Nishina P.M., Naggert J.K. A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene DDR2 in the mouse. Mol. Endocrinol. 2008, 22:1866-1880.
-
(2008)
Mol. Endocrinol.
, vol.22
, pp. 1866-1880
-
-
Kano, K.1
Marin de Evsikova, C.2
Young, J.3
Wnek, C.4
Maddatu, T.P.5
Nishina, P.M.6
Naggert, J.K.7
-
13
-
-
0036479206
-
Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2
-
Olaso E., Labrador J.P., Wang L., Ikeda K., Eng F.J., Klein R., Lovett D.H., Lin H.C., Friedman S.L. Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2. J. Biol. Chem. 2002, 277:3606-3613.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 3606-3613
-
-
Olaso, E.1
Labrador, J.P.2
Wang, L.3
Ikeda, K.4
Eng, F.J.5
Klein, R.6
Lovett, D.H.7
Lin, H.C.8
Friedman, S.L.9
-
14
-
-
1942469341
-
Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling: potential implications in atherosclerosis and lymphangioleiomyomatosis
-
Ferri N., Carragher N.O., Raines E.W. Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling: potential implications in atherosclerosis and lymphangioleiomyomatosis. Am. J. Pathol. 2004, 164:1575-1585.
-
(2004)
Am. J. Pathol.
, vol.164
, pp. 1575-1585
-
-
Ferri, N.1
Carragher, N.O.2
Raines, E.W.3
-
15
-
-
12844287561
-
Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice
-
Xu L., Peng H., Wu D., Hu K., Goldring M.B., Olsen B.R., Li Y. Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice. J. Biol. Chem. 2005, 280:548-555.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 548-555
-
-
Xu, L.1
Peng, H.2
Wu, D.3
Hu, K.4
Goldring, M.B.5
Olsen, B.R.6
Li, Y.7
-
16
-
-
79951847897
-
An essential role of discoidin domain receptor 2 (DDR2) in osteoblast differentiation and chondrocyte maturation via modulation of Runx2 activation
-
Zhang Y., Su J., Yu J., Bu X., Ren T., Liu X., Yao L. An essential role of discoidin domain receptor 2 (DDR2) in osteoblast differentiation and chondrocyte maturation via modulation of Runx2 activation. J. Bone Miner. Res. 2011, 26:604-617.
-
(2011)
J. Bone Miner. Res.
, vol.26
, pp. 604-617
-
-
Zhang, Y.1
Su, J.2
Yu, J.3
Bu, X.4
Ren, T.5
Liu, X.6
Yao, L.7
-
17
-
-
0025338661
-
A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells
-
Atsumi T., Miwa Y., Kimata K., Ikawa Y. A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells. Cell Differ. Dev. 1990, 30:109-116.
-
(1990)
Cell Differ. Dev.
, vol.30
, pp. 109-116
-
-
Atsumi, T.1
Miwa, Y.2
Kimata, K.3
Ikawa, Y.4
-
18
-
-
0029875398
-
Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor
-
Shukunami C., Shigeno C., Atsumi T., Ishizeki K., Suzuki F., Hiraki Y. Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor. J. Cell Biol. 1996, 133:457-468.
-
(1996)
J. Cell Biol.
, vol.133
, pp. 457-468
-
-
Shukunami, C.1
Shigeno, C.2
Atsumi, T.3
Ishizeki, K.4
Suzuki, F.5
Hiraki, Y.6
-
19
-
-
0031843385
-
Sequential progression of the differentiation program by bone morphogenetic protein-2 in chondrogenic cell line ATDC5
-
Shukunami C., Ohta Y., Sakuda M., Hiraki Y. Sequential progression of the differentiation program by bone morphogenetic protein-2 in chondrogenic cell line ATDC5. Exp. Cell Res. 1998, 241:1-11.
-
(1998)
Exp. Cell Res.
, vol.241
, pp. 1-11
-
-
Shukunami, C.1
Ohta, Y.2
Sakuda, M.3
Hiraki, Y.4
-
20
-
-
0030788922
-
Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro
-
Shukunami C., Ishizeki K., Atsumi T., Ohta Y., Suzuki F., Hiraki Y. Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro. J. Bone Miner. Res. 1997, 12:1174-1188.
-
(1997)
J. Bone Miner. Res.
, vol.12
, pp. 1174-1188
-
-
Shukunami, C.1
Ishizeki, K.2
Atsumi, T.3
Ohta, Y.4
Suzuki, F.5
Hiraki, Y.6
-
21
-
-
0035980055
-
P21Cip-1/SDI-1/WAF-1 gene is involved in chondrogenic differentiation of ATDC5 cells in vitro
-
Negishi Y., Ui N., Nakajima M., Kawashima K., Maruyama K., Takizawa T., Endo H. p21Cip-1/SDI-1/WAF-1 gene is involved in chondrogenic differentiation of ATDC5 cells in vitro. J. Biol. Chem. 2001, 276:33249-33256.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33249-33256
-
-
Negishi, Y.1
Ui, N.2
Nakajima, M.3
Kawashima, K.4
Maruyama, K.5
Takizawa, T.6
Endo, H.7
-
22
-
-
77953319991
-
Pannexin 3 regulates intracellular ATP/cAMP levels and promotes chondrocyte differentiation
-
Iwamoto T., Nakamura T., Doyle A., Ishikawa M., de Vega S., Fukumoto S., Yamada Y. Pannexin 3 regulates intracellular ATP/cAMP levels and promotes chondrocyte differentiation. J. Biol. Chem. 2010, 285:18948-18958.
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 18948-18958
-
-
Iwamoto, T.1
Nakamura, T.2
Doyle, A.3
Ishikawa, M.4
de Vega, S.5
Fukumoto, S.6
Yamada, Y.7
-
23
-
-
78649980063
-
The effects of Sp7/Osterix gene silencing in the chondroprogenitor cell line ATDC5
-
Omoteyama K., Takagi M. The effects of Sp7/Osterix gene silencing in the chondroprogenitor cell line ATDC5. Biochem. Biophys. Res. Commun. 2010, 403:242-246.
-
(2010)
Biochem. Biophys. Res. Commun.
, vol.403
, pp. 242-246
-
-
Omoteyama, K.1
Takagi, M.2
-
24
-
-
0038687536
-
Developmental regulation of the growth plate
-
Kronenberg H.M. Developmental regulation of the growth plate. Nature 2003, 423:332-336.
-
(2003)
Nature
, vol.423
, pp. 332-336
-
-
Kronenberg, H.M.1
-
25
-
-
1642545091
-
Essential role of hypertrophic chondrocytes in endochondral bone development
-
Chung U.I. Essential role of hypertrophic chondrocytes in endochondral bone development. Endocr. J. 2004, 51:19-24.
-
(2004)
Endocr. J.
, vol.51
, pp. 19-24
-
-
Chung, U.I.1
-
26
-
-
71849093619
-
Transcriptional networks controlling skeletal development
-
Hartmann C. Transcriptional networks controlling skeletal development. Curr. Opin. Genet. Dev. 2009, 19:437-443.
-
(2009)
Curr. Opin. Genet. Dev.
, vol.19
, pp. 437-443
-
-
Hartmann, C.1
-
27
-
-
0035179839
-
DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells
-
Olaso E., Ikeda K., Eng F.J., Xu L., Wang L.H., Lin H.C., Friedman S.L. DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells. J. Clin. Invest. 2001, 108:1369-1378.
-
(2001)
J. Clin. Invest.
, vol.108
, pp. 1369-1378
-
-
Olaso, E.1
Ikeda, K.2
Eng, F.J.3
Xu, L.4
Wang, L.H.5
Lin, H.C.6
Friedman, S.L.7
-
28
-
-
58149105329
-
Regulation of collagen fibrillogenesis by cell-surface expression of kinase dead DDR2
-
Blissett A.R., Garbellini D., Calomeni E.P., Mihai C., Elton T.S., Agarwal G. Regulation of collagen fibrillogenesis by cell-surface expression of kinase dead DDR2. J. Mol. Biol. 2009, 385:902-911.
-
(2009)
J. Mol. Biol.
, vol.385
, pp. 902-911
-
-
Blissett, A.R.1
Garbellini, D.2
Calomeni, E.P.3
Mihai, C.4
Elton, T.S.5
Agarwal, G.6
-
29
-
-
0029819450
-
Separable cis-regulatory elements that contribute to tissue- and site-specific alpha 2(XI) collagen gene expression in the embryonic mouse cartilage
-
Tsumaki N., Kimura T., Matsui Y., Nakata K., Ochi T. Separable cis-regulatory elements that contribute to tissue- and site-specific alpha 2(XI) collagen gene expression in the embryonic mouse cartilage. J. Cell Biol. 1996, 134:1573-1582.
-
(1996)
J. Cell Biol.
, vol.134
, pp. 1573-1582
-
-
Tsumaki, N.1
Kimura, T.2
Matsui, Y.3
Nakata, K.4
Ochi, T.5
-
30
-
-
33745657464
-
Ars insulator identified in sea urchin possesses an activity to ensure the transgene expression in mouse cells
-
Tajima S., Shinohara K., Fukumoto M., Zaitsu R., Miyagawa J., Hino S., Fan J., Akasaka K., Matsuoka M. Ars insulator identified in sea urchin possesses an activity to ensure the transgene expression in mouse cells. J. Biochem. 2006, 139:705-714.
-
(2006)
J. Biochem.
, vol.139
, pp. 705-714
-
-
Tajima, S.1
Shinohara, K.2
Fukumoto, M.3
Zaitsu, R.4
Miyagawa, J.5
Hino, S.6
Fan, J.7
Akasaka, K.8
Matsuoka, M.9
-
32
-
-
58049221026
-
Mutations in DDR2 gene cause SMED with short limbs and abnormal calcifications
-
Bargal R., Cormier-Daire V., Ben-Neriah Z., Le Merrer M., Sosna J., Melki J., Zangen D.H., Smithson S.F., Borochowitz Z., Belostotsky R., Raas-Rothschild A. Mutations in DDR2 gene cause SMED with short limbs and abnormal calcifications. Am. J. Hum. Genet. 2009, 84:80-84.
-
(2009)
Am. J. Hum. Genet.
, vol.84
, pp. 80-84
-
-
Bargal, R.1
Cormier-Daire, V.2
Ben-Neriah, Z.3
Le Merrer, M.4
Sosna, J.5
Melki, J.6
Zangen, D.H.7
Smithson, S.F.8
Borochowitz, Z.9
Belostotsky, R.10
Raas-Rothschild, A.11
-
33
-
-
77953514278
-
Trafficking defects and loss of ligand binding are the underlying causes of all reported DDR2 missense mutations found in SMED-SL patients
-
Ali B.R., Xu H., Akawi N.A., John A., Karuvantevida N.S., Langer R., Al-Gazali L., Leitinger B. Trafficking defects and loss of ligand binding are the underlying causes of all reported DDR2 missense mutations found in SMED-SL patients. Hum. Mol. Genet. 2010, 19:2239-2250.
-
(2010)
Hum. Mol. Genet.
, vol.19
, pp. 2239-2250
-
-
Ali, B.R.1
Xu, H.2
Akawi, N.A.3
John, A.4
Karuvantevida, N.S.5
Langer, R.6
Al-Gazali, L.7
Leitinger, B.8
-
34
-
-
78349240652
-
Transcriptional upregulation of DDR2 by ATF4 facilitates osteoblastic differentiation through p38 MAPK-mediated Runx2 activation
-
Lin K.L., Chou C.H., Hsieh S.C., Hwa S.Y., Lee M.T., Wang F.F. Transcriptional upregulation of DDR2 by ATF4 facilitates osteoblastic differentiation through p38 MAPK-mediated Runx2 activation. J. Bone Miner. Res. 2010, 25:2489-2503.
-
(2010)
J. Bone Miner. Res.
, vol.25
, pp. 2489-2503
-
-
Lin, K.L.1
Chou, C.H.2
Hsieh, S.C.3
Hwa, S.Y.4
Lee, M.T.5
Wang, F.F.6
-
35
-
-
11144354938
-
Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog
-
Yoshida C.A., Yamamoto H., Fujita T., Furuichi T., Ito K., Inoue K., Yamana K., Zanma A., Takada K., Ito Y., Komori T. Runx2 and Runx3 are essential for chondrocyte maturation, and Runx2 regulates limb growth through induction of Indian hedgehog. Genes Dev. 2004, 18:952-963.
-
(2004)
Genes Dev.
, vol.18
, pp. 952-963
-
-
Yoshida, C.A.1
Yamamoto, H.2
Fujita, T.3
Furuichi, T.4
Ito, K.5
Inoue, K.6
Yamana, K.7
Zanma, A.8
Takada, K.9
Ito, Y.10
Komori, T.11
-
36
-
-
10744224227
-
Runx2 deficiency in chondrocytes causes adipogenic changes in vitro
-
Enomoto H., Furuichi T., Zanma A., Yamana K., Yoshida C., Sumitani S., Yamamoto H., Enomoto-Iwamoto M., Iwamoto M., Komori T. Runx2 deficiency in chondrocytes causes adipogenic changes in vitro. J. Cell Sci. 2004, 117:417-425.
-
(2004)
J. Cell Sci.
, vol.117
, pp. 417-425
-
-
Enomoto, H.1
Furuichi, T.2
Zanma, A.3
Yamana, K.4
Yoshida, C.5
Sumitani, S.6
Yamamoto, H.7
Enomoto-Iwamoto, M.8
Iwamoto, M.9
Komori, T.10
-
37
-
-
3142707223
-
Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling
-
Fujita T., Azuma Y., Fukuyama R., Hattori Y., Yoshida C., Koida M., Ogita K., Komori T. Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling. J. Cell Biol. 2004, 166:85-95.
-
(2004)
J. Cell Biol.
, vol.166
, pp. 85-95
-
-
Fujita, T.1
Azuma, Y.2
Fukuyama, R.3
Hattori, Y.4
Yoshida, C.5
Koida, M.6
Ogita, K.7
Komori, T.8
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