메뉴 건너뛰기




Volumn 427, Issue 3, 2012, Pages 611-617

Discoidin domain receptor 2 (DDR2) regulates proliferation of endochondral cells in mice

Author keywords

ATDC5 cell; Chondrocyte; Discoidin domain receptor 2 (DDR2); MiRNA; Transgenic mice

Indexed keywords

DISCOIDIN DOMAIN RECEPTOR 2; INSULIN; MESSENGER RNA; MICRORNA; PROTEIN TYROSINE KINASE; TRANSCRIPTION FACTOR RUNX2; UNCLASSIFIED DRUG;

EID: 84867873768     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2012.09.106     Document Type: Article
Times cited : (20)

References (37)
  • 1
    • 34648819975 scopus 로고    scopus 로고
    • Structural basis of the collagen-binding mode of discoidin domain receptor 2
    • Ichikawa O., Osawa M., Nishida N., Goshima N., Nomura N., Shimada I. Structural basis of the collagen-binding mode of discoidin domain receptor 2. Embo J. 2007, 26:4168-4176.
    • (2007) Embo J. , vol.26 , pp. 4168-4176
    • Ichikawa, O.1    Osawa, M.2    Nishida, N.3    Goshima, N.4    Nomura, N.5    Shimada, I.6
  • 2
    • 0031309902 scopus 로고    scopus 로고
    • The discoidin domain receptor tyrosine kinases are activated by collagen
    • Vogel W., Gish G.D., Alves F., Pawson T. The discoidin domain receptor tyrosine kinases are activated by collagen. Mol. Cell 1997, 1:13-23.
    • (1997) Mol. Cell , vol.1 , pp. 13-23
    • Vogel, W.1    Gish, G.D.2    Alves, F.3    Pawson, T.4
  • 3
    • 33646341752 scopus 로고    scopus 로고
    • Sensing extracellular matrix: an update on discoidin domain receptor function
    • Vogel W.F., Abdulhussein R., Ford C.E. Sensing extracellular matrix: an update on discoidin domain receptor function. Cell Signal. 2006, 18:1108-1116.
    • (2006) Cell Signal. , vol.18 , pp. 1108-1116
    • Vogel, W.F.1    Abdulhussein, R.2    Ford, C.E.3
  • 4
    • 33746831573 scopus 로고    scopus 로고
    • The discoidin domain receptor DDR2 is a receptor for type X collagen
    • Leitinger B., Kwan A.P. The discoidin domain receptor DDR2 is a receptor for type X collagen. Matrix Biol. 2006, 25:355-364.
    • (2006) Matrix Biol. , vol.25 , pp. 355-364
    • Leitinger, B.1    Kwan, A.P.2
  • 5
    • 0032921366 scopus 로고    scopus 로고
    • Discoidin domain receptors: Structural relations and functional implications
    • Vogel W. Discoidin domain receptors: Structural relations and functional implications. Faseb. J. 1999, (Suppl. 13):S77-82.
    • (1999) Faseb. J. , Issue.SUPPL. 13
    • Vogel, W.1
  • 6
    • 0037125948 scopus 로고    scopus 로고
    • Binding of discoidin domain receptor 2 to collagen I: an atomic force microscopy investigation
    • Agarwal G., Kovac L., Radziejewski C., Samuelsson S.J. Binding of discoidin domain receptor 2 to collagen I: an atomic force microscopy investigation. Biochemistry 2002, 41:11091-11098.
    • (2002) Biochemistry , vol.41 , pp. 11091-11098
    • Agarwal, G.1    Kovac, L.2    Radziejewski, C.3    Samuelsson, S.J.4
  • 8
    • 8544270883 scopus 로고    scopus 로고
    • The D2 period of collagen II contains a specific binding site for the human discoidin domain receptor DDR2
    • Leitinger B., Steplewski A., Fertala A. The D2 period of collagen II contains a specific binding site for the human discoidin domain receptor DDR2. J. Mol. Biol. 2004, 344:993-1003.
    • (2004) J. Mol. Biol. , vol.344 , pp. 993-1003
    • Leitinger, B.1    Steplewski, A.2    Fertala, A.3
  • 9
    • 0035176409 scopus 로고    scopus 로고
    • Discoidin domain receptor (DDR) 1 and 2: collagen-activated tyrosine kinase receptors in the cornea
    • Mohan R.R., Wilson S.E. Discoidin domain receptor (DDR) 1 and 2: collagen-activated tyrosine kinase receptors in the cornea. Exp. Eye Res. 2001, 72:87-92.
    • (2001) Exp. Eye Res. , vol.72 , pp. 87-92
    • Mohan, R.R.1    Wilson, S.E.2
  • 10
    • 0028799694 scopus 로고
    • Distinct structural characteristics of discoidin I subfamily receptor tyrosine kinases and complementary expression in human cancer
    • Alves F., Vogel W., Mossie K., Millauer B., Hofler H., Ullrich A. Distinct structural characteristics of discoidin I subfamily receptor tyrosine kinases and complementary expression in human cancer. Oncogene 1995, 10:609-618.
    • (1995) Oncogene , vol.10 , pp. 609-618
    • Alves, F.1    Vogel, W.2    Mossie, K.3    Millauer, B.4    Hofler, H.5    Ullrich, A.6
  • 12
    • 48249091732 scopus 로고    scopus 로고
    • A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene DDR2 in the mouse
    • Kano K., Marin de Evsikova C., Young J., Wnek C., Maddatu T.P., Nishina P.M., Naggert J.K. A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene DDR2 in the mouse. Mol. Endocrinol. 2008, 22:1866-1880.
    • (2008) Mol. Endocrinol. , vol.22 , pp. 1866-1880
    • Kano, K.1    Marin de Evsikova, C.2    Young, J.3    Wnek, C.4    Maddatu, T.P.5    Nishina, P.M.6    Naggert, J.K.7
  • 13
    • 0036479206 scopus 로고    scopus 로고
    • Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2
    • Olaso E., Labrador J.P., Wang L., Ikeda K., Eng F.J., Klein R., Lovett D.H., Lin H.C., Friedman S.L. Discoidin domain receptor 2 regulates fibroblast proliferation and migration through the extracellular matrix in association with transcriptional activation of matrix metalloproteinase-2. J. Biol. Chem. 2002, 277:3606-3613.
    • (2002) J. Biol. Chem. , vol.277 , pp. 3606-3613
    • Olaso, E.1    Labrador, J.P.2    Wang, L.3    Ikeda, K.4    Eng, F.J.5    Klein, R.6    Lovett, D.H.7    Lin, H.C.8    Friedman, S.L.9
  • 14
    • 1942469341 scopus 로고    scopus 로고
    • Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling: potential implications in atherosclerosis and lymphangioleiomyomatosis
    • Ferri N., Carragher N.O., Raines E.W. Role of discoidin domain receptors 1 and 2 in human smooth muscle cell-mediated collagen remodeling: potential implications in atherosclerosis and lymphangioleiomyomatosis. Am. J. Pathol. 2004, 164:1575-1585.
    • (2004) Am. J. Pathol. , vol.164 , pp. 1575-1585
    • Ferri, N.1    Carragher, N.O.2    Raines, E.W.3
  • 15
    • 12844287561 scopus 로고    scopus 로고
    • Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice
    • Xu L., Peng H., Wu D., Hu K., Goldring M.B., Olsen B.R., Li Y. Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice. J. Biol. Chem. 2005, 280:548-555.
    • (2005) J. Biol. Chem. , vol.280 , pp. 548-555
    • Xu, L.1    Peng, H.2    Wu, D.3    Hu, K.4    Goldring, M.B.5    Olsen, B.R.6    Li, Y.7
  • 16
    • 79951847897 scopus 로고    scopus 로고
    • An essential role of discoidin domain receptor 2 (DDR2) in osteoblast differentiation and chondrocyte maturation via modulation of Runx2 activation
    • Zhang Y., Su J., Yu J., Bu X., Ren T., Liu X., Yao L. An essential role of discoidin domain receptor 2 (DDR2) in osteoblast differentiation and chondrocyte maturation via modulation of Runx2 activation. J. Bone Miner. Res. 2011, 26:604-617.
    • (2011) J. Bone Miner. Res. , vol.26 , pp. 604-617
    • Zhang, Y.1    Su, J.2    Yu, J.3    Bu, X.4    Ren, T.5    Liu, X.6    Yao, L.7
  • 17
    • 0025338661 scopus 로고
    • A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells
    • Atsumi T., Miwa Y., Kimata K., Ikawa Y. A chondrogenic cell line derived from a differentiating culture of AT805 teratocarcinoma cells. Cell Differ. Dev. 1990, 30:109-116.
    • (1990) Cell Differ. Dev. , vol.30 , pp. 109-116
    • Atsumi, T.1    Miwa, Y.2    Kimata, K.3    Ikawa, Y.4
  • 18
    • 0029875398 scopus 로고    scopus 로고
    • Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor
    • Shukunami C., Shigeno C., Atsumi T., Ishizeki K., Suzuki F., Hiraki Y. Chondrogenic differentiation of clonal mouse embryonic cell line ATDC5 in vitro: differentiation-dependent gene expression of parathyroid hormone (PTH)/PTH-related peptide receptor. J. Cell Biol. 1996, 133:457-468.
    • (1996) J. Cell Biol. , vol.133 , pp. 457-468
    • Shukunami, C.1    Shigeno, C.2    Atsumi, T.3    Ishizeki, K.4    Suzuki, F.5    Hiraki, Y.6
  • 19
    • 0031843385 scopus 로고    scopus 로고
    • Sequential progression of the differentiation program by bone morphogenetic protein-2 in chondrogenic cell line ATDC5
    • Shukunami C., Ohta Y., Sakuda M., Hiraki Y. Sequential progression of the differentiation program by bone morphogenetic protein-2 in chondrogenic cell line ATDC5. Exp. Cell Res. 1998, 241:1-11.
    • (1998) Exp. Cell Res. , vol.241 , pp. 1-11
    • Shukunami, C.1    Ohta, Y.2    Sakuda, M.3    Hiraki, Y.4
  • 20
    • 0030788922 scopus 로고    scopus 로고
    • Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro
    • Shukunami C., Ishizeki K., Atsumi T., Ohta Y., Suzuki F., Hiraki Y. Cellular hypertrophy and calcification of embryonal carcinoma-derived chondrogenic cell line ATDC5 in vitro. J. Bone Miner. Res. 1997, 12:1174-1188.
    • (1997) J. Bone Miner. Res. , vol.12 , pp. 1174-1188
    • Shukunami, C.1    Ishizeki, K.2    Atsumi, T.3    Ohta, Y.4    Suzuki, F.5    Hiraki, Y.6
  • 21
    • 0035980055 scopus 로고    scopus 로고
    • P21Cip-1/SDI-1/WAF-1 gene is involved in chondrogenic differentiation of ATDC5 cells in vitro
    • Negishi Y., Ui N., Nakajima M., Kawashima K., Maruyama K., Takizawa T., Endo H. p21Cip-1/SDI-1/WAF-1 gene is involved in chondrogenic differentiation of ATDC5 cells in vitro. J. Biol. Chem. 2001, 276:33249-33256.
    • (2001) J. Biol. Chem. , vol.276 , pp. 33249-33256
    • Negishi, Y.1    Ui, N.2    Nakajima, M.3    Kawashima, K.4    Maruyama, K.5    Takizawa, T.6    Endo, H.7
  • 23
    • 78649980063 scopus 로고    scopus 로고
    • The effects of Sp7/Osterix gene silencing in the chondroprogenitor cell line ATDC5
    • Omoteyama K., Takagi M. The effects of Sp7/Osterix gene silencing in the chondroprogenitor cell line ATDC5. Biochem. Biophys. Res. Commun. 2010, 403:242-246.
    • (2010) Biochem. Biophys. Res. Commun. , vol.403 , pp. 242-246
    • Omoteyama, K.1    Takagi, M.2
  • 24
    • 0038687536 scopus 로고    scopus 로고
    • Developmental regulation of the growth plate
    • Kronenberg H.M. Developmental regulation of the growth plate. Nature 2003, 423:332-336.
    • (2003) Nature , vol.423 , pp. 332-336
    • Kronenberg, H.M.1
  • 25
    • 1642545091 scopus 로고    scopus 로고
    • Essential role of hypertrophic chondrocytes in endochondral bone development
    • Chung U.I. Essential role of hypertrophic chondrocytes in endochondral bone development. Endocr. J. 2004, 51:19-24.
    • (2004) Endocr. J. , vol.51 , pp. 19-24
    • Chung, U.I.1
  • 26
    • 71849093619 scopus 로고    scopus 로고
    • Transcriptional networks controlling skeletal development
    • Hartmann C. Transcriptional networks controlling skeletal development. Curr. Opin. Genet. Dev. 2009, 19:437-443.
    • (2009) Curr. Opin. Genet. Dev. , vol.19 , pp. 437-443
    • Hartmann, C.1
  • 27
    • 0035179839 scopus 로고    scopus 로고
    • DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells
    • Olaso E., Ikeda K., Eng F.J., Xu L., Wang L.H., Lin H.C., Friedman S.L. DDR2 receptor promotes MMP-2-mediated proliferation and invasion by hepatic stellate cells. J. Clin. Invest. 2001, 108:1369-1378.
    • (2001) J. Clin. Invest. , vol.108 , pp. 1369-1378
    • Olaso, E.1    Ikeda, K.2    Eng, F.J.3    Xu, L.4    Wang, L.H.5    Lin, H.C.6    Friedman, S.L.7
  • 29
    • 0029819450 scopus 로고    scopus 로고
    • Separable cis-regulatory elements that contribute to tissue- and site-specific alpha 2(XI) collagen gene expression in the embryonic mouse cartilage
    • Tsumaki N., Kimura T., Matsui Y., Nakata K., Ochi T. Separable cis-regulatory elements that contribute to tissue- and site-specific alpha 2(XI) collagen gene expression in the embryonic mouse cartilage. J. Cell Biol. 1996, 134:1573-1582.
    • (1996) J. Cell Biol. , vol.134 , pp. 1573-1582
    • Tsumaki, N.1    Kimura, T.2    Matsui, Y.3    Nakata, K.4    Ochi, T.5
  • 33
    • 77953514278 scopus 로고    scopus 로고
    • Trafficking defects and loss of ligand binding are the underlying causes of all reported DDR2 missense mutations found in SMED-SL patients
    • Ali B.R., Xu H., Akawi N.A., John A., Karuvantevida N.S., Langer R., Al-Gazali L., Leitinger B. Trafficking defects and loss of ligand binding are the underlying causes of all reported DDR2 missense mutations found in SMED-SL patients. Hum. Mol. Genet. 2010, 19:2239-2250.
    • (2010) Hum. Mol. Genet. , vol.19 , pp. 2239-2250
    • Ali, B.R.1    Xu, H.2    Akawi, N.A.3    John, A.4    Karuvantevida, N.S.5    Langer, R.6    Al-Gazali, L.7    Leitinger, B.8
  • 34
    • 78349240652 scopus 로고    scopus 로고
    • Transcriptional upregulation of DDR2 by ATF4 facilitates osteoblastic differentiation through p38 MAPK-mediated Runx2 activation
    • Lin K.L., Chou C.H., Hsieh S.C., Hwa S.Y., Lee M.T., Wang F.F. Transcriptional upregulation of DDR2 by ATF4 facilitates osteoblastic differentiation through p38 MAPK-mediated Runx2 activation. J. Bone Miner. Res. 2010, 25:2489-2503.
    • (2010) J. Bone Miner. Res. , vol.25 , pp. 2489-2503
    • Lin, K.L.1    Chou, C.H.2    Hsieh, S.C.3    Hwa, S.Y.4    Lee, M.T.5    Wang, F.F.6
  • 37
    • 3142707223 scopus 로고    scopus 로고
    • Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling
    • Fujita T., Azuma Y., Fukuyama R., Hattori Y., Yoshida C., Koida M., Ogita K., Komori T. Runx2 induces osteoblast and chondrocyte differentiation and enhances their migration by coupling with PI3K-Akt signaling. J. Cell Biol. 2004, 166:85-95.
    • (2004) J. Cell Biol. , vol.166 , pp. 85-95
    • Fujita, T.1    Azuma, Y.2    Fukuyama, R.3    Hattori, Y.4    Yoshida, C.5    Koida, M.6    Ogita, K.7    Komori, T.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.