INF-β1b therapy modulates l-arginine and nitric oxide metabolism in patients with relapse remittent multiple sclerosis

Journal of the Neurological Sciences

Volumn 323, Issue 1-2, 2012, Pages 187-192

  Stojanovic, Ivana ^a   Vojinovic, Slobodan ^b   Ljubisavljevic, Srdjan ^a,b   Pavlovic, Radmila ^a   Basic, Jelena ^a   Pavlovic, Dusica ^a   Ilic, Andjelka ^b   Cvetkovic, Tatjana ^a   Stukalov, Maja ^a  

^a UNIVERSITY OF NI   (Serbia)

^b University Clinical Centre of Nis   (Serbia)

Author keywords

3 Nitrotyrosine; ADMA; Arginase; INF 1b; Multiple sclerosis; Nitric oxide; S nitrosothiols; SDMA

Indexed keywords

3 NITROTYROSINE; 6 N,N' DIMETHYLARGININE; ARGINASE; ARGININE; INTERFERON BETA SERINE; N(G),N(G) DIMETHYLARGININE; NITRATE; NITRIC OXIDE; NITROGEN DIOXIDE; S NITROSOTHIOL;

ADULT; AMINO ACID BLOOD LEVEL; AMINO ACID METABOLISM; ARTICLE; BLOOD LEVEL; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE COURSE; ENZYME ACTIVITY; FEMALE; HUMAN; MALE; MULTIPLE SCLEROSIS; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RELAPSE; STATISTICAL SIGNIFICANCE;

ADULT; ARGINASE; ARGININE; BIOLOGICAL MARKERS; DRUG MONITORING; FEMALE; FOLLOW-UP STUDIES; HUMANS; INFLAMMATION; INTERFERON-BETA; MALE; MIDDLE AGED; MULTIPLE SCLEROSIS, RELAPSING-REMITTING; NITRATES; NITRIC OXIDE; NITRITES; NITROSO COMPOUNDS; SEVERITY OF ILLNESS INDEX; SULFHYDRYL COMPOUNDS; TYROSINE; YOUNG ADULT;

EID: 84867872945     PISSN: 0022510X     EISSN: 18785883     Source Type: Journal    
DOI: 10.1016/j.jns.2012.09.014     Document Type: Article

References (37)

1. H. Lassman Pathology of multiple sclerosis A. Compston, G. Ebers, H. Lassman, I. Mc Donald, B. Mathews, H. Wekerle, Mc Alpine's multiple sclerosis third edition 1998 Churchill Livingstone London 323 358
2. B.D. Trapp, R. Ransohoff, and R. Rudick Axonal pathology in multiple sclerosis: relationship to neurologic disability Curr Opin Neurol 12 1999 295 302
3. P. Ghafourifar, K. Mousavizadeh, M.S. Prihar, R.P. Nazarewicz, A. Parihar, and W.J. Zenebe Mitochondria in multiple sclerosis Front Biosci 13 2008 3116 3126
4. M. Koch, J. Mostert, A. Arutjunyan, M. Stepanov, A. Teelken, and D. Heersema Peripheral blood leukocyte NO production and oxidative stress in multiple sclerosis Mult Scler 14 2 2008 159 165
5. S. Ibragic, E. Sofic, E. Suljic, N. Avdagic, A. Bajraktarevic, and I. Tahirovic Serum nitric oxide concentrations in patients with multiple sclerosis and patients with epilepsy J Neural Transm 119 1 2011 7 11
6. C.F. Brosnan, L. Battistini, C.S. Raine, D.W. Dickson, A. Casadevall, and S.C. Lee Reactive nitrogen intermediates in human neuropathology: an overview Dev Neurosci 16 1994 152 161
7. O. Bagasra, F.H. Michaels, Y.M. Zheng, L.E. Bobroski, S.V. Spitsin, and Z.F. Fu Activation of the inducible form of nitric oxide synthase in the brains of patients with multiple sclerosis Proc Natl Acad Sci U S A 92 26 1995 12041 12045
8. A.H. Cross, R.M. Keeling, S. Goorha, M. San, C. Rodi, and P.S. Wyatt Inducible nitric oxide synthase gene expression and enzyme activity correlate with disease activity in murine experimental autoimmune encephalomyelitis J Neuroimmunol 71 1-2 1996 145 153
9. D.A. Wink, K.S. Kasprzak, C.M. Maragos, R.K. Elesperu, M. Misra, and T.M. Dunams DNA deaminating ability and genotoxicity of nitric oxide and its progenitors Science 254 1991 1001 1003
10. K. Rejdak, A. Petzold, Z. Stelmasiak, and G. Giovanoni Cerebrospinal fluid proteins in relation to nitric oxide metabolites during relapse of multiple sclerosis Mult Scler 14 1 2008 59 66
11. A.I. Danilov, M. Andersson, N. Bavand, N.P. Wiklund, T. Olsson, and L. Brundin Nitric oxide metabolite determinations reveal continuous inflammation in multiple sclerosis J Neuroimmunol 136 2003 112 118
12. O. Bizzozero, G. DeJesus, H.A. Bixler, and A. Pastuszyn Evidence of nitrosative damage in the brain white matter of patients with multiple sclerosis Neurochem Res 30 1 2005 139 149
13. K.R. Pang, J.J. We, D.B. Huang, S.K. Tyring, and S. Baron Biological and clinical basis for molecular studies of interferons Methods Mol Med 116 2005 1 23
14. J.A. Navaro-Gonzalvez, C. Garcia-Benayas, and J. Arenas Semi automated measurement of nitrate in biological fluids Clin Chem 44 1998 679 681
15. Y. Minamiyama, S. Takamura, and M. Inoue Effect of thiol status on nitric oxide metabolism in the circulation Arch Biochem Biophys 341 1 1997 186 192
16. D. Giustarini, A. Milzani, I. Dalle-Donne, and R. Rossi Detection of S-nitrosothiols in biological fluids: a comparison among the most widely applied methodologies J Chromatogr B Analyt Technol Biomed Life Sci 851 1-2 2007 124 139
17. Z. Porembska, and M. Kedra Early diagnosis of myocardial infarction by arginase activity determination Clin Chim Acta 60 1975 355 361
18. J. Pi, Y. Kumagai, G. Sun, and N. Shimojo Improved method for simultaneous determination of l-arginine and its mono- and dimethylated metabolites in biological samples by high-performance liquid chromatography J Chromatogr B Biomed Sci Appl 742 1 2000 199 203
19. T.L. Sorensen, M. Tani, J. Jensen, V. Pierce, C. Lucchinetti, and V.A. Folcik Expression of specific chemokines and chemokine receptors in the central nervous system of multiple sclerosis patients J Clin Invest 103 1999 807 815
20. A. Bitsch, J. Schuchardt, S. Bunkowski, T. Kuhlmann, and W. Bruck Acute axonal injury in multiple sclerosis. Correlation with demyelination and inflammation Brain 123 Pt6 2000 1174 1183
21. J.M. Encinas, L. Manganas, and G. Enikolopov Nitric oxide and multiple sclerosis Curr Neurol Neurosci Rep 5 3 2005 232 238
22. K. Rejdak, A. Petzold, T. Kocki, J. Kurzepa, P. Frieb, and Z. Stelmasiak CSF nitric oxide metabolites are associated with activity and progression of multiple sclerosis Neurology 63 8 2004 1439 1445
23. E.J. Redford, R. Kapoor, and K.J. Smith Nitric oxide donors reversibly block axonal conduction: demyelinated axons are especially susceptible Brain 120 1997 2149 2157
24. M.C. Broillet S-nitrosylation of proteins Cell Mol Life Sci 55 1996 1036 1042
25. M. Roghani, F. Mahboudi, M.A. Saharian, M. Etemadifar, A.N. Esfahani, and H. Nahrevanian Concentrations of nitric oxide metabolites in the serum of Iranian multiple sclerosis patients J Neurol Sci 294 1-2 2010 92 94
26. W.C. Stewart, G. Giovannoni, J.M. Land, I. McDonald, J.B. Clark, and J.R. Heales Pretreatment of astrocytes with interferon α/β impairs interferon-γ induction of nitric oxide synthase J Neurochem 68 1998 2547 2551
27. W.C. Stewart, J.M. Land, J.B. Clark, and J.R. Heales Pretreatment of astrocytes with interferon α/β prevents neuronal mitochondrial respiratory chain damage J Neurochem 70 1997 432 434
28. K. Lieb, S. Engels, and B.L. Fiebich Inhibition of LPS induced iNOS and NO synthesis in primary rat microglial cells Neurochem Int 42 2 2003 131 137
29. E. Miller, A. Walczak, J. Saluk, M.B. Ponczek, and I. Majsterek Oxidative modification of patient's plasma proteins and its role in pathogenesis of multiple sclerosis Clin Biochem 45 1-2 2011 26 30
30. V.R. Drel, S. Lupachyk, H. Shevalye, I. Vareniuk, W. Xu, and J. Zhang New therapeutic and biomarker discovery for peripheral diabetic neuropathy: PARP inhibitor, nitrotyrosine, and tumor necrosis factor-α Endocrinology 151 6 2010 2547 2555
31. M.W. Foster, T.J. McMahon, and J.S. Stamler S-nitrosylation in health and disease Trends Mol Med 9 2003 160 168
32. M.T. Frost, B. Halliwell, and K.P. Moore Analysis of free and nitrotyrosine in human plasma by a gas chromatography/mass spectrometry method that avoids nitration artifacts Biochem J 345 2000 453 458
33. E.B. Jude, A.J.M. Boulton, M.W.J. Ferguson, and I. Appleton The role of nitric oxide synthase and arginase in the pathogenesis of diabetic foot ulcers: possible modulatory effects by transforming growth factor beta 1 Diabetologia 42 1999 748 757
34. G. Wu, and Morris JrSM Arginine metabolism: nitric oxide and beyond Biochem J 336 Pt1 1998 1 17
35. A. Hrabák, T. Bajor, A. Temesi, and G. Mészáros The inhibitory effect of nitrite, a stable product of nitric oxide (NO) formation, on arginase FEBS Lett 390 2 1996 203 206
36. J. Leiper, and P. Vallance Biological significance of endogenous methylarginines that inhibit nitric oxide synthases Cardiovasc Res 43 1999 542 548
37. + carrier hCAT-2B Nitric Oxide 1 1997 65 73