Copper-64 radiolabeling and biological evaluation of bifunctional chelators for radiopharmaceutical development

Nuclear Medicine and Biology

Volumn 39, Issue 8, 2012, Pages 1099-1104

  De Silva, Ravindra A ^a   Jain, Sandeep ^a   Lears, Kimberly A ^a   Chong, Hyun Soon ^b   Kang, Chi Soo ^b   Sun, Xiang ^b   Rogers, Buck E ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Illinois Institute of Technology   (United States)

Author keywords

Bifunctional chelators; Biodistribution; Copper 64; Serum stability

Indexed keywords

1,4,7 TRIAZACYCLONONANE 1,4,7 TRIACETIC ACID; 4 CARBOXYMETHYL 7 [2 (CARBOXYMETHYLAMINO) 3 (4 NITROPHENYL)PROPYL][1,4,7]TRIAZONAN 1 YL ACETIC ACID; 4 CARBOXYMETHYL 7 [2 [CARBOXYMETHYL(4 NITROBENZYL)AMINO]ETHYL][1,4,7]TRIAZONAN 1 YL ACETIC ACID; CHELATING AGENT; COPPER 64; RADIOPHARMACEUTICAL AGENT; TETRAXETAN; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; COMPLEX FORMATION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG STABILITY; DRUG STRUCTURE; IN VITRO STUDY; IN VIVO STUDY; INCUBATION TIME; ISOTOPE LABELING; MOUSE; NONHUMAN; RADIOACTIVITY; ROOM TEMPERATURE; SPECTROPHOTOMETRY;

ANIMALS; CHELATING AGENTS; COPPER RADIOISOTOPES; DRUG DISCOVERY; DRUG STABILITY; FEMALE; HETEROCYCLIC COMPOUNDS; ISOTOPE LABELING; KINETICS; MICE; RADIOPHARMACEUTICALS; RATS; TEMPERATURE;

EID: 84867849110     PISSN: 09698051     EISSN: 18729614     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2012.05.009     Document Type: Article

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