메뉴 건너뛰기




Volumn 31, Issue 6, 2004, Pages 795-802

Development of a spectroscopic assay for bifunctional ligand-protein conjugates based on copper

Author keywords

Arsenazo III; Copper 64; Ligand to protein ratio; Monoclonal antibodies; Radioimmunotherapy; UV Vis spectroscopy

Indexed keywords

2 (4 ISOTHIOCYANATOBENZYL) 1,4,7 TRIAZACYCLONONANE 1,4,7 TRIACETIC ACID; 2 (4 ISOTHIOCYANATOBENZYL) 1,4,8,11 TETRAAZACYCLOTETRADECANE N,N',N'',N''' TETRAACETIC ACID; ARSENAZO 3; COPPER COMPLEX; LIGAND; MACROCYCLIC COMPOUND; MONOCLONAL ANTIBODY; PROTEIN; PYRIDINE DERIVATIVE; TACHPYRIDINE; TRASTUZUMAB; UNCLASSIFIED DRUG;

EID: 3042707742     PISSN: 09698051     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nucmedbio.2004.04.004     Document Type: Article
Times cited : (43)

References (37)
  • 1
    • 0035988624 scopus 로고    scopus 로고
    • Monoclonal Antibody-Based Therapy Strategies: Providing options for the cancer patient
    • Milenic D.E. Monoclonal Antibody-Based Therapy Strategies Providing options for the cancer patient. Curr Pharm Design. 8:2002;1749-1764
    • (2002) Curr Pharm Design , vol.8 , pp. 1749-1764
    • Milenic, D.E.1
  • 2
    • 36148962457 scopus 로고    scopus 로고
    • Recent Advances in Antibody Drug Conjugates for Cancer Therapy
    • Meyer D.L., Senter P.D. Recent Advances in Antibody Drug Conjugates for Cancer Therapy. Annu Rep Med Chem. 38:2003;229-237
    • (2003) Annu Rep Med Chem , vol.38 , pp. 229-237
    • Meyer, D.L.1    Senter, P.D.2
  • 3
    • 0142250392 scopus 로고    scopus 로고
    • Targeted Anti-Interleukin-6 Monoclonal Antibody Therapy for Cancer: A Review of the Rationale and Clinical Evidence
    • Trikha M., Corringham R., Klein B., Rossi J.F. Targeted Anti-Interleukin-6 Monoclonal Antibody Therapy for Cancer A Review of the Rationale and Clinical Evidence. Clin Cancer Res. 9:2003;4653-4665
    • (2003) Clin Cancer Res , vol.9 , pp. 4653-4665
    • Trikha, M.1    Corringham, R.2    Klein, B.3    Rossi, J.F.4
  • 4
    • 0029785102 scopus 로고    scopus 로고
    • Pharmacokinetics of Monoclonal Antibodies - Implications for their use in Cancer Therapy
    • Pedley R.B. Pharmacokinetics of Monoclonal Antibodies - Implications for their use in Cancer Therapy. Clin Immunother. 6:1996;54-67
    • (1996) Clin Immunother , vol.6 , pp. 54-67
    • Pedley, R.B.1
  • 5
    • 0012725753 scopus 로고    scopus 로고
    • Therapeutic Radiopharmaceuticals
    • Volkert W.A., Hoffman T.J. Therapeutic Radiopharmaceuticals. Chem Rev. 99:1999;2269-2292
    • (1999) Chem Rev , vol.99 , pp. 2269-2292
    • Volkert, W.A.1    Hoffman, T.J.2
  • 6
    • 0035155042 scopus 로고    scopus 로고
    • Bifunctional Chelators for Therapeutic Lanthanide Radiopharmaceuticals
    • Liu S., Edwards D.S. Bifunctional Chelators for Therapeutic Lanthanide Radiopharmaceuticals. Bioconjugate Chem. 12:2001;7-34
    • (2001) Bioconjugate Chem , vol.12 , pp. 7-34
    • Liu, S.1    Edwards, D.S.2
  • 7
    • 0030111464 scopus 로고    scopus 로고
    • Vehicles, Chelators, and Radionuclides: Choosing the "building Blocks" of an Effective Therapeutic Radioimmunoconjugate
    • Schubiger P.A., Alberto R., Smith A. Vehicles, Chelators, and Radionuclides Choosing the "Building Blocks" of an Effective Therapeutic Radioimmunoconjugate. Bioconjugate Chem. 7:1996;165-179
    • (1996) Bioconjugate Chem , vol.7 , pp. 165-179
    • Schubiger, P.A.1    Alberto, R.2    Smith, A.3
  • 8
    • 84987453854 scopus 로고
    • Chelate Radiochemistry: Cleavable Linkers Lead to Altered Levels of Radioactivity in the Liver
    • Meares C.F., McCall M.J., Deshpande S.V., DeNardo S.J., Goodwin D.A. Chelate Radiochemistry Cleavable Linkers Lead to Altered Levels of Radioactivity in the Liver. Int J Cancer Suppl. 2:1988;99-102
    • (1988) Int J Cancer Suppl , vol.2 , pp. 99-102
    • Meares, C.F.1    McCall, M.J.2    Deshpande, S.V.3    Denardo, S.J.4    Goodwin, D.A.5
  • 9
    • 0028273007 scopus 로고
    • Homodimeric and Heterodimeric Bis(amino thiol) Oxometal Complexes with Rhenium(V) and Technetium(V). Control of Heterodimeric Complex Formation and an Approach to Metal Complexes that Mimic Steroid Hormones
    • Chi D.Y., O'Neil J.P., Anderson C.J., Welch M.J., Katzenellenbogen J.A. Homodimeric and Heterodimeric Bis(amino thiol) Oxometal Complexes with Rhenium(V) and Technetium(V). Control of Heterodimeric Complex Formation and an Approach to Metal Complexes that Mimic Steroid Hormones. J Med Chem. 37:1994;928-937
    • (1994) J Med Chem , vol.37 , pp. 928-937
    • Chi, D.Y.1    O'Neil, J.P.2    Anderson, C.J.3    Welch, M.J.4    Katzenellenbogen, J.A.5
  • 10
    • 0026889408 scopus 로고
    • Spectrophotometric Method for the Determination of a Bifunctional DTPA Ligand in DTPA-Monoclonal Antibody Conjugates
    • Pippin C.G., Parker T.A., McMurry T.J., Brechbiel M.W. Spectrophotometric Method for the Determination of a Bifunctional DTPA Ligand in DTPA-Monoclonal Antibody Conjugates. Bioconjugate Chem. 3:1992;342-354
    • (1992) Bioconjugate Chem , vol.3 , pp. 342-354
    • Pippin, C.G.1    Parker, T.A.2    McMurry, T.J.3    Brechbiel, M.W.4
  • 11
    • 0033380104 scopus 로고    scopus 로고
    • Spectrophotometric Method for Determination of Bifunctional Macrocyclic Ligands in Macrocyclic Ligand-Protein Conjugates
    • Dadachova E., Chappell L.L., Brechbiel M.W. Spectrophotometric Method for Determination of Bifunctional Macrocyclic Ligands in Macrocyclic Ligand-Protein Conjugates. Nucl Med Biol. 26:1999;977-982
    • (1999) Nucl Med Biol , vol.26 , pp. 977-982
    • Dadachova, E.1    Chappell, L.L.2    Brechbiel, M.W.3
  • 12
    • 0022968394 scopus 로고
    • Synthesis of 1-(p-Isothiocyanatobenzyl) Derivatives of DTPA and EDTA - Antibody Labeling and Tumor-Imaging Studies
    • Brechbiel M.W., Gansow O.A., Atcher R.W., Schlom J., Esteban J., Simpson D.E., Colcher D. Synthesis of 1-(p-Isothiocyanatobenzyl) Derivatives of DTPA and EDTA - Antibody Labeling and Tumor-Imaging Studies. Inorg Chem. 25:1986;2772-2781
    • (1986) Inorg Chem , vol.25 , pp. 2772-2781
    • Brechbiel, M.W.1    Gansow, O.A.2    Atcher, R.W.3    Schlom, J.4    Esteban, J.5    Simpson, D.E.6    Colcher, D.7
  • 13
    • 0001397445 scopus 로고
    • A new bifunctional chelate, N-(2-hydroxy-3,5-dimethylbenzyl)-N'-(2- hydroxy-5-(bromoacetamido)benzyl)ethylenediamine-N,N'-diacetic acid (BrMe2HBED) an effective conjugate for radiometals and antibodies
    • Mathias C.J., Sun Y., Connett J.M., Philpott G.W., Welch M.J., Martell A.E. A new bifunctional chelate, N-(2-hydroxy-3, 5-dimethylbenzyl)-N'-(2- hydroxy-5-(bromoacetamido)benzyl)ethylenediamine-N, N'-diacetic acid (BrMe2HBED) an effective conjugate for radiometals and antibodies. Inorg Chem. 29:1990;1475-1480
    • (1990) Inorg Chem , vol.29 , pp. 1475-1480
    • Mathias, C.J.1    Sun, Y.2    Connett, J.M.3    Philpott, G.W.4    Welch, M.J.5    Martell, A.E.6
  • 14
    • 0021067628 scopus 로고
    • Optimization of the DTPA Mixed-Anhydride Reaction with Antibodies at Low Concentration
    • Paik C.H., Murphy P.R., Eckelman W.C., Volkert W.A., Reba R.C. Optimization of the DTPA Mixed-Anhydride Reaction with Antibodies at Low Concentration. J Nucl Med. 24:1983;932-936
    • (1983) J Nucl Med , vol.24 , pp. 932-936
    • Paik, C.H.1    Murphy, P.R.2    Eckelman, W.C.3    Volkert, W.A.4    Reba, R.C.5
  • 15
    • 0028535424 scopus 로고
    • A Facile, Water-Soluble Method for Modification of Proteins with DOTA. Use of Elevated Temperature and Optimized pH to Achieve High Specific Activity and High Chelate Stability in Radiolabeled Immunoconjugates
    • Lewis M.R., Raubitschek A., Shively J.E. A Facile, Water-Soluble Method for Modification of Proteins with DOTA. Use of Elevated Temperature and Optimized pH To Achieve High Specific Activity and High Chelate Stability in Radiolabeled Immunoconjugates. Bioconjugate Chem. 5:1994;565-576
    • (1994) Bioconjugate Chem , vol.5 , pp. 565-576
    • Lewis, M.R.1    Raubitschek, A.2    Shively, J.E.3
  • 16
    • 0021512252 scopus 로고
    • Conjugation of Antibodies with Bifunctional Chelating Agents: Isothiocyanate and bromoacetamide reagents, methods of analysis, and subsequent addition of metal ions
    • Meares C.F., McCall M.J., Reardan D.T., Goodwin D.A., Diamanti C.I., McTigue M. Conjugation of Antibodies with Bifunctional Chelating Agents Isothiocyanate and bromoacetamide reagents, methods of analysis, and subsequent addition of metal ions. Anal Biochem. 142:1984;68-78
    • (1984) Anal Biochem , vol.142 , pp. 68-78
    • Meares, C.F.1    McCall, M.J.2    Reardan, D.T.3    Goodwin, D.A.4    Diamanti, C.I.5    McTigue, M.6
  • 17
    • 0035083298 scopus 로고    scopus 로고
    • An Improved Method for Conjugating Monoclonal Antibodies with N-Hydroxysulfosuccinimidyl DOTA
    • Lewis M.R., Kao J.Y., Anderson A.L., Shively J.E., Raubitschek A. An Improved Method for Conjugating Monoclonal Antibodies with N- Hydroxysulfosuccinimidyl DOTA. Bioconjugate Chem. 12:2001;320-324
    • (2001) Bioconjugate Chem , vol.12 , pp. 320-324
    • Lewis, M.R.1    Kao, J.Y.2    Anderson, A.L.3    Shively, J.E.4    Raubitschek, A.5
  • 18
    • 0025988129 scopus 로고
    • Characterization of Antibody-Chelator Conjugates - Determination of Chelator Content by Terbium Fluorescence Titration
    • Brandt K.D., Schnobrich K.E., Johnson D.K. Characterization of Antibody-Chelator Conjugates - Determination of Chelator Content by Terbium Fluorescence Titration. Bioconjugate Chem. 2:1991;67-70
    • (1991) Bioconjugate Chem , vol.2 , pp. 67-70
    • Brandt, K.D.1    Schnobrich, K.E.2    Johnson, D.K.3
  • 20
    • 0000173790 scopus 로고
    • Copper(II) Complexes of Cyclic Tetraazatetraacetic Acids - Unusual Features and Possible Analytical Applications
    • Delgado R., Frausto da Silva J.J.R., Vaz M.C.T.A. Copper(II) Complexes of Cyclic Tetraazatetraacetic Acids - Unusual Features and Possible Analytical Applications. Talanta. 33:1986;285-287
    • (1986) Talanta , vol.33 , pp. 285-287
    • Delgado, R.1    Frausto Da Silva, J.J.R.2    Vaz, M.C.T.A.3
  • 21
    • 0001321081 scopus 로고
    • Stabilities of Divalent and Trivalent Metal Ion Complexes of Macrocyclic Triazatriacetic Acids
    • Delgado R., Sun Y., Motekaitis R.J., Martell A.E. Stabilities of Divalent and Trivalent Metal Ion Complexes of Macrocyclic Triazatriacetic Acids. Inorg Chem. 32:1993;3320-3326
    • (1993) Inorg Chem , vol.32 , pp. 3320-3326
    • Delgado, R.1    Sun, Y.2    Motekaitis, R.J.3    Martell, A.E.4
  • 22
    • 0030292909 scopus 로고    scopus 로고
    • Copper Radionuclides and Radiopharmaceuticals in Nuclear Medicine
    • Blower P.J., Lewis J.S., Zweit J. Copper Radionuclides and Radiopharmaceuticals in Nuclear Medicine. Nucl Med Biol. 23:1996;957-980
    • (1996) Nucl Med Biol , vol.23 , pp. 957-980
    • Blower, P.J.1    Lewis, J.S.2    Zweit, J.3
  • 23
    • 0036596118 scopus 로고    scopus 로고
    • Copper-67 as a therapeutic nuclide for radioimmunotherapy
    • Novak-Hofer I., Schubiger P.A. Copper-67 as a therapeutic nuclide for radioimmunotherapy. Eur J Nucl Med Mol Imaging. 29:2002;821-830
    • (2002) Eur J Nucl Med Mol Imaging , vol.29 , pp. 821-830
    • Novak-Hofer, I.1    Schubiger, P.A.2
  • 25
    • 0026251859 scopus 로고
    • Antibody Labeling with Copper-67 Using the Bifunctional Macrocycle 4-[(1,4,8,11-Tetraazacyclotetradec-1-yl)methyl]benzoic Acid
    • Smith-Jones P.M., Fridrich R., Kaden T.A., Novak-Hofer I., Siebold K., Tschudin D., Maecke H.R. Antibody Labeling with Copper-67 Using the Bifunctional Macrocycle 4-[(1, 4, 8, 11-Tetraazacyclotetradec-1-yl)methyl]benzoic Acid. Bioconjugate Chem. 2:1991;415-421
    • (1991) Bioconjugate Chem , vol.2 , pp. 415-421
    • Smith-Jones, P.M.1    Fridrich, R.2    Kaden, T.A.3    Novak-Hofer, I.4    Siebold, K.5    Tschudin, D.6    Maecke, H.R.7
  • 26
    • 0026889151 scopus 로고
    • Synthesis of Novel 1,4,7-Triazacyclononane-N,N′,N′′- triacetic Acid Derivatives Suitable for Protein Labeling
    • Studer M., Meares C.F. Synthesis of Novel 1, 4, 7-Triazacyclononane-N, N′, N′′-triacetic Acid Derivatives Suitable for Protein Labeling. Bioconjugate Chem. 3:1992;337-341
    • (1992) Bioconjugate Chem , vol.3 , pp. 337-341
    • Studer, M.1    Meares, C.F.2
  • 27
    • 0027603685 scopus 로고
    • Synthesis of 2-(p-Thiocyanatobenzyl)-1,4,7-triazacyclononane-1,4,7- triacetic Acid: Application of the 4-Methoxy-2,3,6-trimethylbenzenesulfonamide Protecting Group in the synthesis of macrocyclic polyamines
    • McMurry T.J., Brechbiel M., Wu C., Gansow O.A. Synthesis of 2-(p-Thiocyanatobenzyl)-1, 4, 7-triazacyclononane-1, 4, 7-triacetic Acid Application of the 4-Methoxy-2, 3, 6-trimethylbenzenesulfonamide Protecting Group in the synthesis of macrocyclic polyamines. Bioconjugate Chem. 4:1993;236-245
    • (1993) Bioconjugate Chem , vol.4 , pp. 236-245
    • McMurry, T.J.1    Brechbiel, M.2    Wu, C.3    Gansow, O.A.4
  • 29
    • 0037111681 scopus 로고    scopus 로고
    • Synthesis of 1,3,5-cis,cis-Triaminocyclohexane N-Pyridyl Derivatives as Potential Antitumor Agents
    • Chong H.-S., Torti F.M., Torti S.V., Brechbiel M.W. Synthesis of 1, 3, 5-cis, cis-Triaminocyclohexane N-Pyridyl Derivatives as Potential Antitumor Agents. J Org Chem. 67:2002;8072-8078
    • (2002) J Org Chem , vol.67 , pp. 8072-8078
    • Chong, H.-S.1    Torti, F.M.2    Torti, S.V.3    Brechbiel, M.W.4
  • 31
    • 0001824671 scopus 로고    scopus 로고
    • The Lowry Method for Protein Quantitation
    • Walker JM, editor. Humana Press, Totowa, NJ
    • Waterborg JH. The Lowry Method for Protein Quantitation. In: Walker JM, editor. Protein Protocols Handbook, 2nd Ed. Humana Press, Totowa, NJ 2002:7-10
    • (2002) Protein Protocols Handbook, 2nd Ed. , pp. 7-10
    • Waterborg, J.H.1
  • 32
  • 33
    • 0018416496 scopus 로고
    • Ellman's reagent: 5,5′-dithiobis(2-nitrobenzoic acid) - A reexamination
    • Riddles P.W., Blakeley R.L., Zerner B. Ellman's reagent 5, 5′-dithiobis(2-nitrobenzoic acid) - a reexamination. Anal Biochem. 94:1979;75-81
    • (1979) Anal Biochem , vol.94 , pp. 75-81
    • Riddles, P.W.1    Blakeley, R.L.2    Zerner, B.3
  • 34
    • 0026487591 scopus 로고
    • A Brief Survey of Methods for Preparing Protein Conjugates with Dyes, Haptens and Cross-Linking Reagents
    • Brinkley M. A Brief Survey of Methods for Preparing Protein Conjugates with Dyes, Haptens and Cross-Linking Reagents. Bioconjugate Chem. 3:1992;2-13
    • (1992) Bioconjugate Chem , vol.3 , pp. 2-13
    • Brinkley, M.1
  • 35
    • 0018247303 scopus 로고
    • Addition of Sulfhydryl Groups to Escherichia coli Ribosomes by Protein Modification with 2-Iminothiolane (Methyl 4-Mercaptobutyrimidate)
    • Jue R., Lambert J.M., Pierce L.R., Traut R.R. Addition of Sulfhydryl Groups to Escherichia coli Ribosomes by Protein Modification with 2-Iminothiolane (Methyl 4-Mercaptobutyrimidate). Biochemistry. 17:1978;5399-5406
    • (1978) Biochemistry , vol.17 , pp. 5399-5406
    • Jue, R.1    Lambert, J.M.2    Pierce, L.R.3    Traut, R.R.4
  • 36
    • 0036074406 scopus 로고    scopus 로고
    • Modifications in Synthesis Strategy Improve the Yield and Efficacy of Geldanamycin-Herceptin Immunoconjugates
    • Mandler R., Kobayashi H., Davis M.Y., Waldmann T.A., Brechbiel M.W. Modifications in Synthesis Strategy Improve the Yield and Efficacy of Geldanamycin-Herceptin Immunoconjugates. Bioconjugate Chem. 13:2002;786-791
    • (2002) Bioconjugate Chem , vol.13 , pp. 786-791
    • Mandler, R.1    Kobayashi, H.2    Davis, M.Y.3    Waldmann, T.A.4    Brechbiel, M.W.5
  • 37
    • 50549175553 scopus 로고
    • Analytical Use of Arsenazo III. Determination of Thorium, Zirconium, Uranium and Rare Earth Elements
    • Savvin S.B. Analytical Use of Arsenazo III. Determination of Thorium, Zirconium, Uranium and Rare Earth Elements. Talanta. 8:1961;673-685
    • (1961) Talanta , vol.8 , pp. 673-685
    • Savvin, S.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.