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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 22, 2012, Pages 6903-6908

Development of triazene prodrugs for ADEPT strategy: New insights into drug delivery system based on carboxypeptidase G2 activation

(4) Capucha, Verónica a Mendes, Eduarda a Francisco, Ana Paula a Perry, M Jesus a

a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA (Portugal)

Author keywords

ADEPT; Carboxypeptidase G2; Intramolecular catalysis; Triazenes

Indexed keywords

ALBUMIN; CARBOXYLIC ACID; CARBOXYPEPTIDASE G2; GLUTAMIC ACID; PRODRUG; TRIAZENE DERIVATIVE;

ANTIBODY DIRECTED ENZYME PRODRUG THERAPY; ARTICLE; CATALYSIS; CHEMICAL REACTION; DECOMPOSITION; DRUG DELIVERY SYSTEM; DRUG MECHANISM; DRUG METABOLISM; DRUG PROTEIN BINDING; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; ENZYME ACTIVATION; ENZYME KINETICS; ENZYME SUBSTRATE; HYDROLYSIS; PLASMA PROTEIN BINDING;

ALKYLATING AGENTS; ANTIBODIES; BACTERIA; DRUG CARRIERS; GAMMA-GLUTAMYL HYDROLASE; GLUTAMIC ACID; HUMANS; KINETICS; PRODRUGS; PROTEIN BINDING; SERUM ALBUMIN; SUBSTRATE SPECIFICITY; TRIAZENES;

BACTERIA (MICROORGANISMS);

EID: 84867847410 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.09.029 Document Type: Article

Times cited : (11)

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