Progression of Oral Squamous Cell Carcinoma Accompanied with Reduced E-Cadherin Expression but Not Cadherin Switch

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Hashimoto, Takashi ^a   Soeno, Yuichi ^a   Maeda, Genta ^a   Taya, Yuji ^a   Aoba, Takaaki ^a   Nasu, Masanori ^a   Kawashiri, Shuichi ^b   Imai, Kazushi ^a  

^a NIPPON DENTAL UNIVERSITY   (Japan)

^b KANAZAWA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

NERVE CELL ADHESION MOLECULE; UVOMORULIN;

ADULT; AGED; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CANCER GROWTH; CARCINOMA CELL; CELL ADHESION; CELL DEDIFFERENTIATION; CELL INVASION; CONTROLLED STUDY; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; IN VITRO STUDY; IN VIVO STUDY; MAJOR CLINICAL STUDY; MOUSE; MOUTH SQUAMOUS CELL CARCINOMA; NONHUMAN; PROTEIN EXPRESSION; PROTEIN LOCALIZATION;

ADULT; AGED; AGED, 80 AND OVER; ANALYSIS OF VARIANCE; ANIMALS; CADHERINS; CARCINOMA, SQUAMOUS CELL; CELL ADHESION; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; MICE; MICE, NUDE; MIDDLE AGED; MOUTH NEOPLASMS; NEOPLASM INVASIVENESS; REAL-TIME POLYMERASE CHAIN REACTION;

EID: 84867844168     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0047899     Document Type: Article

References (42)

1. Choi S, Myers JN, (2008) Molecular pathogenesis of oral squamous cell carcinoma: Implications for therapy. J Dent Res 87: 14-32.
2. Yamamoto E, Kohama G, Sunakawa H, Iwai M, Hiratsuka H, (1983) Mode of invasion, bleomycin sensitivity, and clinical course in squamous cell carcinoma of the oral cavity. Cancer 51: 124-129.
3. Hanahan D, Weinberg RA, (2011) Hallmarks of cancer: the next generation. Cell 144: 646-674.
4. Imai K, Maeda G, Chiba T (2012) Cadherin expression and progression of head and neck squamous cell carcinomas. In: Li X, editor. Squamous Cell Carcinoma. Rijeka: InTech-Open Science. 121-136.
5. Matsuyoshi N, Imamura S, (1997) Multiple cadherins are expressed in human fibroblasts. Biochem Biophys Res Commun 235: 355-358.
6. Kan NG, Stemmler MP, Junghans D, Kanzler B, de Vries WN, et al. (2007) Gene replacement reveals a specific role for E-cadherin in the formation of a functional trophectoderm. Development 134: 31-41.
7. Thiery JP, Acloque H, Huang RYJ, Nieto MA, (2009) Epithelial-mesenchymal transitions in development and disease. Cell 139: 871-90.
8. Wheelock MJ, Shintani Y, Maeda M, Fukumoto Y, Johnson KR, (2008) Cadherin switching. J Cell Sci 121: 727-735.
9. Gasparotto D, Polesel J, Marzotto A, Colladel R, Piccinin S, et al. (2011) Overexpression of TWIST2 correlates with poor prognosis in head and neck squamous cell carcinomas. Oncotarget 2: 1165-1175.
10. Nguyen PT, Kudo Y, Yoshida M, Kamata N, Ogawa I, et al. (2011) N-cadherin expression is involved in malignant behavior of head and neck cancer in relation to epithelial-mesenchymal transition. Histol Histopathol 26: 147-156.
11. Di Domenico M, Pierantoni GM, Feola A, Esposito F, Laino L, et al. (2011) Prognostic significance of N-cadherin expression in oral squamous cell carcinoma. Anticancer Res 31: 4211-4218.
12. Ukpo OC, Thorstad WL, Zang Q, Lewis JS Jr, (2012) Lack of association of cadherin expression and histopathologic type, metastasis, or patient outcome in oropharyngeal squamous cell carcinoma: a tissue microarray study. Head Neck Pathol 6: 38-47.
13. Behrens J, Bakaet L, Friis R, Winterhager E, Van Roy F, et al. (1993) Loss of epithelial differentiation and gain of invasiveness correlates with tyrosine phosphorylation of the E-cadherin/beta-catenin complex in cells transformed with a temperature-sensitive v-SRC gene. J Cell Biol 120: 757-766.
14. Shore EM, Nelson WJ, (1991) Biosynthesis of the cell adhesion molecule uvomorulin (E-cadherin) in Madin-Darby canine kidney epithelial cells. J Biol Chem 266: 19672-19680.
15. Fujita Y, Krause G, Scheffner M, Zechner D, Leddy HE, et al. (2002) Hakai, a c-Cbl-like protein, ubiqutinates and induces endocytosis of the E-cadherin complex. Nat Cell Biol 4: 222-231.
16. Vallorosi CJ, Day KC, Zhao X, Rashid MG, Rubin MA, et al. (2000) Truncation of the beta-catenin binding domain of E-cadherin precedes epithelial apoptosis during prostate and mammary involution. J Biol Chem 275: 3328-3334.
17. Tsuchiya B, Sato Y, Kameya T, Okayasu I, Mukai K, (2006) Differential expression of N-cadherin and E-cadheirn in normal human tissues. Arch Histol Cytol 69: 135-145.
18. Mink SR, Vashistha S, Zhang W, Hodge A, Agus DB, et al. (2010) Cancer-associated fibroblasts derived from EGFR-TKI-resistant tumors reverse EGFR pathway inhibition by EGFR-TKIs. Mol Cancer Res 8: 809-820.
19. Tinkle CL, Lechler T, Pasolli HA, Fuchs E, (2004) Conditional targeting of E-cadherin in skin: insight into hyperproliferative and degenerative responses. Proc Natl Acad Sci U S A 101: 552-557.
20. Perl AK, Wilgenbus P, Dahl U, Semb H, Christofori GA, (1998) A causal role for E-cadherin in the transition from adenoma to carcinoma. Nature 392: 190-193.
21. Kudo Y, Kitajima S, Ogawa I, Hiraoka M, Sargolzaei S, et al. (2004) Invasion and metastasis of oral cancer cells require methylation of E-cadherin and/or degradation of membranous ß-catenin. Clin Cancer Res 10: 5455-5463.
22. Yu CC, Lo WL, Chen YW, Huang PI, Hsu HS, et al. (2011) Bmi-1 regulates Snail expression and promotes metastasis ability in head and neck squamous cancer-derived ALDH1 positive cells. J Oncol 2011:609259. Available: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2948925/?tool=pubmed. Accessed 2012 Apr 23.
23. Maeda G, Chiba T, Okazaki M, Satoh T, Taya Y, et al. (2005) Expression of SIP1 in oral squamous cell carcinomas: Implications for E-cadherin expression and tumor progression. Int J Oncol 27: 1535-1541.
24. Liu H, Komiya S, Shimizu M, Fukunaga Y, Nagafuchi A, (2007) Involvement of p120 carboxy-terminal domain in cadherin trafficking. Cell Struct Funct 32: 127-137.
25. Pyo SW, Hashimoto M, Kim YS, Kim CH, Lee SH, et al. (2007) Expression of E-cadherin, P-cadherin and N-cadherin in oral squamous cell carcinoma: correlation with the clinicopathologic features and patient outcome. J Craniomaxillofac Surg 35: 1-9.
26. Li S, Jiao J, Lu Z, Zhang M, (2009) An essential role for N-cadherin and beta-catenin for progression in tongue squamous cell carcinoma and their effect on invasion and metastasis of Tca8113 tongue cancer cells. Oncol Rep 21: 1223-1233.
27. Zynger DL, Dimov ND, Ho LC, Laskin WB, Yeldandi AV, (2008) Differential expression of neural-cadherin in pulmonary epithelial tumours. Histopatholgy 52: 348-354.
28. Mizunuma H, Miyazawa J, Sanada K, Imai K, (2003) The LIM-only protein, LMO4, and the LIM domain-binding protein, LDB1, expression in squamous cell carcinomas of the oral cavity. Brit J Cancer 88: 1543-1548.
29. Miyazawa J, Mitoro A, Kawashiri S, Chada KK, Imai K, (2004) Expression of mesenchyme-specific gene HMGA2 in squamous cell carcinomas of the oral cavity. Cancer Res 64: 2024-2029.
30. Uraguchi M, Morikawa M, Shirakawa M, Sanada K, Imai K, (2004) Activation of WNT family expression and signaling in squamous cell carcinomas of the oral cavity. J Dent Res 83: 327-332.
31. Maeda G, Chiba T, Kawashiri S, Satoh T, Imai K, (2007) Epigenetic inactivation of IkappaB kinase-alpha in oral carcinomas and tumor progression. Clin Cancer Res 13: 5041-5047.
32. Chiba T, Maeda G, Kawashiri S, Kato K, Imai K, (2009) Epigenetic loss of mucosa-associated lymphoid tissue 1 expression in patients with oral carcinomas. Cancer Res 69: 7216-7223.
33. Wendt MK, Smith JA, Schiemann WP, (2010) Transforming growth facto-ß-induced epithelial-mesenchymal transition facilitates epidermal growth factor-dependent breast cancer progression. Oncogene 29: 6485-6498.
34. Bauer K, Dowejko A, Bosserhoff AK, Reichert TE, Bauer RJ, (2009) P-cadherin induces an epithelial-like phenotype in oral squamous cell carcinoma by GSK-3beta-mediated Snail phosphorylation. Carcinogenesis 30: 1781-1788.
35. Boukamp P, Petrussevska RT, Breitkreutz D, Hornung J, Markham A, et al. (1998) Normal keratinization in a spontaneously immortalized aneuploidy human keratinocyte cell line. J Cell Biol 106: 761-771.
36. Kawashiri S, Kojima K, Kumagai S, Nakagawa K, Yamamoto E, (2001) Effects of chemotherapy on invasion and metastasis of oral cavity cancer in mice. Head Neck 23: 764-7671.
37. Cohen D, Lane B, Jin T, Magi-Galluzzi C, Finke J, et al. (2007) The prognostic significance of epidermal growth factor receptor expression in clear-cell renal cell carcinoma: a call for standardized methods in immunohistochemical evaluation. Clin Genitourin Cancer 5: 264-270.
38. Langer C, Ratschek M, Rehak P, Schips L, Zigeuner R, (2004) Are heterogenous results of EGFR immunoreactivity in renal cell carcinoma related to non-standardized criteria for staining evaluation? J Clin Pathol 57: 773-775.
39. Anbalagan M, Moroz K, Ali A, Carrier L, Glodowski S, et al. (2012) Subcellular localization of total and activated Src kinase in African American and Caucasian breast cancer. PLoS ONE 7: e33017.
40. Zhang JY, Wang Y, Zhang D, Yang ZQ, Dong XJ, et al. (2010) ∂-catenin promotes malignant phenotype of non-small cell lung cancer by non-competitive binding of E-cadherin with p120ctn in cytoplasm. J Pathol 222: 76-88.
41. Srinivasan R, Gillett CE, Barnes DM, Gullick WJ, (2000) Nuclear expression of the c-erbB-4/HER-4 growth factor receptor in invasive breast cancer. Cancer Res 60: 1483-1487.
42. Schmittgen DD, Livak KJ, (2008) Analyzing real-time PCR data by the comparative CT method. Nat Protoc 6: 1101-1108.