Mechanism-based small molecule cross-linkers of HECT E3 ubiquitin ligase-substrate pairs

Biochemistry

Volumn 51, Issue 42, 2012, Pages 8327-8329

  Park, Sungjin ^a   Ntai, Ioanna ^a   Thomas, Paul ^a   Konishcheva, Evgeniia ^a   Kelleher, Neil L ^a   Statsuk, Alexander V ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIFUNCTIONAL; COVALENT CROSS-LINKS; COVALENTLY CROSS-LINKED; CROSS-LINKERS; CYS RESIDUES; ELECTROPHILES; MODEL SUBSTRATES; SMALL MOLECULES; UBIQUITIN; UBIQUITIN LIGASES; UBIQUITINATION;

CROSSLINKING;

SUBSTRATES;

UBIQUITIN PROTEIN LIGASE E3;

ARTICLE; ENZYME MECHANISM; ENZYME SUBSTRATE; PRIORITY JOURNAL; PROTEIN CROSS LINKING; PROTEIN PROTEIN INTERACTION; UBIQUITINATION;

BINDING SITES; CROSS-LINKING REAGENTS; CYCLIN-DEPENDENT KINASE INHIBITOR PROTEINS; CYSTEINE; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; LYSINE; PEPTIDE FRAGMENTS; SACCHAROMYCES CEREVISIAE PROTEINS; UBIQUITIN-PROTEIN LIGASE COMPLEXES; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84867821332     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi301231h     Document Type: Article

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