Decorin is a part of the ovarian extracellular matrix in primates and may act as a signaling molecule

Human Reproduction

Volumn 27, Issue 11, 2012, Pages 3249-3258

  Adam, M ^a   Saller, S ^a   Strobl S ^a   Hennebold, J D ^b,c   Dissen, G A ^b   Ojeda, S R ^b   Stouffer, R L ^b,c   Berg, D ^d   Berg, U ^d   Mayerhofer, A ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^c OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^d Assisted Reproductive Technologies Bogenhausen   (Germany)

Author keywords

apoptosis; corpus luteum; epidermal growth factor receptor; follicle; reactive oxygen species

Indexed keywords

CALCIUM; CASPASE 3; CASPASE 7; DECORIN; EPIDERMAL GROWTH FACTOR RECEPTOR; MESSENGER RNA; REACTIVE OXYGEN METABOLITE;

ARTICLE; CALCIUM CELL LEVEL; CELL SURVIVAL; CONNECTIVE TISSUE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; EXTRACELLULAR MATRIX; FEMALE; FERTILIZATION IN VITRO; GRANULOSA CELL; HUMAN; IMMUNOHISTOCHEMISTRY; LUTEAL CELL; NONHUMAN; OVARY; OVARY FOLLICLE FLUID; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; QUANTITATIVE ASSAY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHESUS MONKEY; WESTERN BLOTTING;

EID: 84867817873     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/des297     Document Type: Article

References (46)

1. Adam M, Schwarzer JU, Kohn FM, Strauss L, Poutanen M, Mayerhofer A. Mast cell tryptase stimulates production of decorin by human testicular peritubular cells: possible role of decorin in male infertility by interfering with growth factor signaling. Hum Reprod 2011;26:2613-2625.
2. Adam M, Urbanski HF, Garyfallou VT, Schwarzer JU, Welsch U, Köhn FM, Strauss L, Poutanen M, Mayerhofer M. High levels of the extracellular matrix proteoglycan decorin are associated with inhibition of testicular function. Int J Androl 2012;35:550-561.
3. Ben-Ami I, Freimann S, Armon L, Dantes A, Ron-El R, Amsterdam A. Novel function of ovarian growth factors: combined studies by DNA m icroarray, biochemical and physiological approaches. Mol Hum Reprod 2006;12:413-419.
4. Bogan RL, Murphy MJ, Stouffer RL, Hennebold JD. Systematic determination of differential gene expression in the primate corpus luteum during the luteal phase of the menstrual cycle. Mol Endocrinol 2008;22:1260-1273.
5. Bulling A, Berg FD, Berg U, Duffy DM, Stouffer RL, Ojeda SR, Gratzl M, Mayerhofer A. Identification of an ovarian voltage-activated Na+-channel type: hints to involvement in luteolysis. Mol Endocrinol 2000;14:1064-1074.
6. Conti M, Hsieh M, Park JY, Su YQ. Role of the epidermal growth factor network in ovarian follicles. Mol Endocrinol 2006;20:715-723.
7. Csordas G, Santra M, Reed CC, Eichstetter I, McQuillan DJ, Gross D, Nugent MA, Hajnoczky G, Iozzo RV. Sustained down-regulation of the epidermal growth factor receptor by decorin. A mechanism for controlling tumor growth in vivo. J Biol Chem 2000;275:32879-32887.
8. Finkel T. Signal transduction by reactive oxygen species. J Cell Biol 2011; 194:7-15.
9. Goldoni S, Humphries A, Nystrom A, Sattar S, Owens RT, McQuillan DJ, Ireton K, Iozzo RV. Decorin is a novel antagonistic ligand of the Met receptor. J Cell Biol 2009;185:743-754.
10. Grisaru D, Hauspy J, Prasad M, Albert M, Murphy KJ, Covens A, Macgregor PF, Rosen B. Microarray expression identification of differentially expressed genes in serous epithelial ovarian cancer compared with bulk normal ovarian tissue and ovarian surface scrapings. Oncol Rep 2007;18:1347-1356.
11. Hsieh M, Thao K, Conti M. Genetic dissection of epidermal growth factor receptor signaling during luteinizing hormone-induced oocyte maturation. PLoS One 2011;6:e21574.
12. Humaidan P, Westergaard LG, Mikkelsen AL, Fukuda M, Yding Andersen C. Levels of the epidermal growth factor-like peptide amphiregulin in follicular fluid reflect the mode of triggering ovulation: a comparison between gonadotrophin-releasing hormone agonist and urinary human chorionic gonadotrophin. Fertil Steril 2011; 95:2034-2038.
13. Iacob D, Cai J, Tsonis M, Babwah A, Chakraborty C, Bhattacharjee RN, Lala PK. Decorin-mediated inhibition of proliferation and migration of the human trophoblast via different tyrosine kinase receptors. Endocrinology 2008;149:6187-6197.
14. Inoue Y, Miyamoto S, Fukami T, Shirota K, Yotsumoto F, Kawarabayashi T. Amphiregulin is much more abundantly expressed than transforming growth factor-alpha and epidermal growth factor in human follicular fluid obtained from patients undergoing in vitro fertilization-embryo transfer. Fertil Steril 2009;91:1035-1041.
15. Iozzo RV, Schaefer L. Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans. FEBS J 2010;277:3864-3875.
16. Iozzo RV, Moscatello DK, McQuillan DJ, Eichstetter I. Decorin is a biological ligand for the epidermal growth factor receptor. J Biol Chem 1999;274:4489-4492.
17. Irving-Rodgers HF, Friden BE, Morris SE, Mason HD, Brannstrom M, Sekiguchi K, Sanzen N, Sorokin LM, Sado Y, Ninomiya Y et al. Extracellular matrix of the human cyclic corpus luteum. Mol Hum Reprod 2006;12:525-534.
18. Irving-Rodgers HF, Hummitzsch K, Murdiyarso LS, Bonner WM, Sado Y, Ninomiya Y, Couchman JR, Sorokin LM, Rodgers RJ. Dynamics of extracellular matrix in ovarian follicles and corpora lutea of mice. Cell Tissue Res 2010;339:613-624.
19. Ivey ME, Little PJ. Thrombin regulates vascular smooth muscle cell proteoglycan synthesis via PAR-1 and multiple downstream signalling pathways. Thromb Res 2008;123:288-297.
20. Karakida S, Kawano Y, Utsunomiya Y, Furukawa Y, Sasaki T, Narahara H. Effect of heparin-binding EGF-like growth factor and amphiregulin on the MAP kinase-induced production of vascular endothelial growth factor by human granulosa cells. Growth Factors 2011;29:271-277.
21. Khan SM, Oliver RH, Yeh J. Epidermal growth factor receptor inhibition by tyrphostin 51 induces apoptosis in luteinized granulosa cells. J Clin Endocrinol Metab 2005;90:469-473.
22. Kim EH, Na HK, Kim DH, Park SA, Kim HN, Song NY, Surh YJ. 15-Deoxy-Delta12, 14-prostaglandin J2 induces COX-2 expression through Akt-driven AP-1 activation in human breast cancer cells: a potential role of ROS. Carcinogenesis 2008;29:688-695.
23. Kwintkiewicz J, Giudice LC. The interplay of insulin-like growth f actors, g onadotropins, and endocrine disruptors in ovarian follicular development and function. Semin Reprod Med 2009;27:43-51.
24. Mauviel A, Santra M, Chen YQ, Uitto J, Iozzo RV. Transcriptional regulation of decorin gene expression. Induction by quiescence and repression by tumor necrosis factor-alpha. J Biol Chem 1995; 270:11692-11700.
25. Mayerhofer A, Fohr KJ, Sterzik K, Gratzl M. Carbachol increases intracellular free calcium concentrations in human granulosa-lutein cells. J Endocrinol 1992;135:153-159.
26. Mayerhofer A, Sterzik K, Link H, Wiemann M, Gratzl M. Effect of oxytocin on free intracellular Ca2+ levels and progesterone release by human granulosa-lutein cells. J Clin Endocrinol Metab 1993;77:1209-1214.
27. Mayerhofer A, Hemmings HC Jr., Snyder GL, Greengard P, Boddien S, Berg U, Brucker C. Functional dopamine-1 receptors and DARPP-32 are expressed in human ovary and granulosa luteal cells in vitro. J Clin Endocrinol Metab 1999;84:257-264.
28. Mayerhofer A, Kunz L, Krieger A, Proskocil B, Spindel E, Amsterdam A, Dissen GA, Ojeda SR, Wessler I. FSH regulates acetycholine production by ovarian granulosa cells. Reprod Biol Endocrinol 2006;4:37.
29. McArthur ME, Irving-Rodgers HF, Byers S, Rodgers RJ. Identification and immunolocalization of d ecorin, v ersican, p erlecan, n idogen, and chondroitin sulfate proteoglycans in bovine small-antral ovarian follicles. Biol Reprod 2000;63:913-924.
30. Nili N, Cheema AN, Giordano FJ, Barolet AW, Babaei S, Hickey R, Eskandarian MR, Smeets M, Butany J, Pasterkamp G et al. Decorin inhibition of PDGF-stimulated vascular smooth muscle cell function: potential mechanism for inhibition of intimal hyperplasia after balloon angioplasty. Am J Pathol 2003;163:869-878.
31. Park JY, Su YQ, Ariga M, Law E, Jin SL, Conti M. EGF-like growth factors as mediators of LH action in the ovulatory follicle. Science 2004; 303:682-684.
32. Peluffo MC, Ting AY, Zamah AM, Conti M, Stouffer RL, Zelinski MB, Hennebold JD. Amphiregulin promotes the maturation of oocytes isolated from the small antral follicles of the rhesus macaque. Hum Reprod 2012;27:2430-2437.
33. Pulkkinen L, Alitalo T, Krusius T, Peltonen L. Expression of decorin in human tissues and cell lines and defined chromosomal assignment of the gene locus (DCN). Cytogenet Cell Genet 1992;60:107-111.
34. Reed CC, Iozzo RV. The role of decorin in collagen fibrillogenesis and skin homeostasis. Glycoconj J 2002;19:249-255.
35. Rey-Ares V, Lazarov N, Berg D, Berg U, Kunz L, Mayerhofer A. Dopamine receptor repertoire of human granulosa cells. Reprod Biol Endocrinol 2007;5:40.
36. Ricciardelli C, Rodgers RJ. Extracellular matrix of ovarian tumors. Semin Reprod Med 2006;24:270-282.
37. Saller S, Kunz L, Dissen GA, Stouffer R, Ojeda SR, Berg D, Berg U, Mayerhofer A. Oxytocin receptors in the primate ovary: molecular identity and link to apoptosis in human granulosa cells. Hum Reprod. 2010;25:969-976.
38. Saller S, Merz-Lange J, Raffael S, Hecht S, Pavlik R, Thaler C, Berg D, Berg U, Kunz L, Mayerhofer A. Norepinephrine, active norepinephrine transporter and norepinephrine-metabolism are involved in the generation of reactive oxygen species in human ovarian granulosa cells. Endocrinology 2012;153:1472-1483.
39. Santra M, Reed CC, Iozzo RV. Decorin binds to a narrow region of the epidermal growth factor (EGF) r eceptor, partially overlapping but distinct from the EGF-binding epitope. J Biol Chem 2002; 277:35671-35681.
40. Schaefer L, Iozzo RV. Biological functions of the small leucine-rich proteoglycans: from genetics to signal transduction. J Biol Chem 2008; 283:21305-21309.
41. Shkolnik K, Tadmor A, Ben-Dor S, Nevo N, Galiani D, Dekel N. Reactive oxygen species are indispensable in ovulation. Proc Natl Acad Sci USA 2011;108:1462-1467.
42. Ungefroren H, Ergun S, Krull NB, Holstein AF. Expression of the small proteoglycans biglycan and decorin in the adult human testis. Biol Reprod 1995;52:1095-1105.
43. Wegrowski Y, Paltot V, Gillery P, Kalis B, Randoux A, Maquart FX. Stimulation of sulphated glycosaminoglycan and decorin production in adult dermal fibroblasts by recombinant human interleukin-4. Biochem J 1995;307:673-678.
44. Xu F, Stouffer RL, Müller J, Hennebold JD, Wright JW, Bahar A, Leder G, Peters M, Thorne M, Sims M et al. Dynamics of the transcriptome in the primate ovulatory follicle. Mol Hum Reprod 2011;17:152-165.
45. Yu Y, Yan J, Li M, Yan L, Zhao Y, Lian Y, Li R, Liu P, Qiao J. Effects of combined epidermal growth f actor, brain-derived neurotrophic factor and insulin-like growth factor-1 on human oocyte maturation and early fertilized and cloned embryo development. Hum. Reprod 2012; 27:2146-2159.
46. Zhu JX, Goldoni S, Bix G, Owens RT, McQuillan DJ, Reed CC, Iozzo RV. Decorin evokes protracted internalization and degradation of the epidermal growth factor receptor via caveolar endocytosis. J Biol Chem 2005;280:32468-32479.