Microarray expression identification of differentially expressed genes in serous epithelial ovarian cancer compared with bulk normal ovarian tissue and ovarian surface scrapings

Oncology Reports

Volumn 18, Issue 6, 2007, Pages 1347-1356

  Grisaru, Dan ^a,c   Hauspy, Jan ^a   Prasad, Mona ^a   Albert, Monique ^a   Murphy, K Joan ^a   Covens, Allan ^b   Macgregor, Pascale F ^a   Rosen, Barry ^a  

^a PRINCESS MARGARET HOSPITAL   (Canada)

^b DEPARTMENT OF RADIATION ONCOLOGY   (Canada)

^c TEL AVIV SOURASKY MEDICAL CENTER   (Israel)

Author keywords

Activin A receptor; Decorin; Microarrays; Osteopontin; Serous epithelial ovarian cancer; Tumor necrosis factor

Indexed keywords

RNA;

ARTICLE; CANCER STAGING; CYTOLOGY; DNA MICROARRAY; FEMALE; GENETICS; HUMAN; NEOPLASM; OVARY; OVARY TUMOR; PATHOLOGY; PHYSIOLOGY; REFERENCE VALUE; VAGINA SMEAR;

FEMALE; HUMANS; NEOPLASM STAGING; NEOPLASMS, GLANDULAR AND EPITHELIAL; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; OVARIAN NEOPLASMS; OVARY; REFERENCE VALUES; RNA, NEOPLASM; VAGINAL SMEARS;

EID: 38449118399     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.18.6.1347     Document Type: Article

References (43)

1. Jemal A, Murray T, Ward E, et al: Cancer statistics, 2005. CA Cancer J Clin 55: 10-30, 2005. (Pubitemid 40310185)
2. Kosary CL: FIGO stage, histology, histologic grade, age and race as prognostic factors in determining survival for cancers of the female gynecological system: an analysis of 1973-87 SEER cases of cancers of the endometrium, cervix, ovary, vulva, and vagina. Semin Surg Oncol 10: 31-46, 1994.
3. Engel J, Eckel R, Schubert-Fritschle G, et al: Moderate progress for ovarian cancer in the last 20 years: prolongation of survival, but no improvement in the cure rate. Eur J Cancer 38: 2435-2445, 2002. (Pubitemid 35387497)
4. Tusher VG, Tibshirani R and Chu G: Significance analysis of microarrays applied to the ionizing radiation response. Proc Natl Acad Sci USA 98: 5116-5121, 2001. (Pubitemid 32397092)
5. Bayani J, Brenton JD, Macgregor PF, et al: Parallel analysis of sporadic primary ovarian carcinomas by spectral karyotyping, comparative genomic hybridization, and expression microarrays. Cancer Res 62: 3466-3476, 2002. (Pubitemid 34651394)
6. Brazma A, Hingamp P, Quackenbush J, et al: Minimum information about a microarray experiment (MIAME)-toward standards for microarray data. Nat Genet 29: 365-371, 2001. (Pubitemid 34326681)
7. Eisen MB, Spellman PT, Brown PO and Botstein D: Cluster analysis and display of genome-wide expression patterns. Proc Natl Acad Sci USA 95: 14863-14868, 1998. (Pubitemid 29003722)
8. Trogan E, Choudhury RP, Dansky HM, Rong JX, Breslow JL and Fisher EA: Laser capture microdissection analysis of gene expression in macrophages from atherosclerotic lesions of apolipoprotein E-deficient mice. Proc Natl Acad Sci USA 99: 2234-2239, 2002. (Pubitemid 34169044)
9. Garber ME, Troyanskaya OG, Schluens K, et al: Diversity of gene expression in adenocarcinoma of the lung. Proc Natl Acad Sci USA 98: 13784-13789, 2001. (Pubitemid 33115976)
10. Bittner M, Meltzer P, Chen Y, et al: Molecular classification of cutaneous malignant melanoma by gene expression profiling. Nature 406: 536-540, 2000. (Pubitemid 30625740)
11. Perou CM, Jeffrey SS, van de Rijn M, et al: Distinctive gene expression patterns in human mammary epithelial cells and breast cancers. Proc Natl Acad Sci USA 96: 9212-9217, 1999. (Pubitemid 29374734)
12. Alizadeh AA, Eisen MB, Davis RE, et al: Distinct types of diffuse large B-cell lymphoma identified by gene expression profiling. Nature 403: 503-511, 2000. (Pubitemid 30082188)
13. Alon U, Barkai N, Notterman DA, et al: Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays. Proc Natl Acad Sci USA 96: 6745-6750, 1999. (Pubitemid 29274954)
14. Luo J, Duggan DJ, Chen Y, et al: Human prostate cancer and benign prostatic hyperplasia: molecular dissection by gene expression profiling. Cancer Res 61: 4683-4688, 2001. (Pubitemid 32691876)
15. Selaru FM, Zou T, Xu Y, et al: Global gene expression profiling in Barrett's esophagus and esophageal cancer: a comparative analysis using cDNA microarrays. Oncogene 21: 475-478, 2002. (Pubitemid 34123809)
16. Bingle L, Singleton V and Bingle CD: The putative ovarian tumour marker gene HE4 (WFDC2), is expressed in normal tissues and undergoes complex alternative splicing to yield multiple protein isoforms. Oncogene 21: 2768-2773, 2002. (Pubitemid 34478335)
17. Kim JH, Skates SJ, Uede T, et al: Osteopontin as a potential diagnostic biomarker for ovarian cancer. JAMA 287: 1671-1679, 2002. (Pubitemid 34289219)
18. Di Simone N, Crowley WF Jr, Wang QF, Sluss PM and Schneyer AL: Characterization of inhibin/activin subunit, follistatin, and activin type II receptors in human ovarian cancer cell lines: a potential role in autocrine growth regulation. Endocrinology 137: 486-494, 1996. (Pubitemid 26049884)
19. Fuller PJ, Zumpe ET, Chu S, Mamers P and Burger HG: Inhibin-activin receptor subunit gene expression in ovarian tumors. J Clin Endocrinol Metab 87: 1395-1401, 2002. (Pubitemid 36121114)
20. Hough CD, Cho KR, Zonderman AB, Schwartz DR and Morin PJ: Coordinately up-regulated genes in ovarian cancer. Cancer Res 61: 3869-3876, 2001. (Pubitemid 32720943)
21. De Cecco L, Marchionni L, Gariboldi M, et al: Gene expression profiling of advanced ovarian cancer: characterization of a molecular signature involving fibroblast growth factor 2. Oncogene 23: 8171-8183, 2004.
22. Huddleston HG, Wong KK, Welch WR, Berkowitz RS and Mok SC: Clinical applications of microarray technology: creatine kinase B is an up-regulated gene in epithelial ovarian cancer and shows promise as a serum marker. Gynecol Oncol 96: 77-83, 2005. (Pubitemid 39612421)
23. Lee BC, Cha K, Avraham S and Avraham HK: Microarray analysis of differentially expressed genes associated with human ovarian cancer. Int J Oncol 24: 847-851, 2004.
24. Zhang X, Feng J, Cheng Y, et al : Characterization of differentially expressed genes in ovarian cancer by cDNA microarrays. Int J Gynecol Cancer 15: 50-57, 2005. (Pubitemid 40194333)
25. Hough CD, Sherman-Baust CA, Pizer ES, et al : Large-scale serial analysis of gene expression reveals genes differentially expressed in ovarian cancer. Cancer Res 60: 6281-6287, 2000.
26. Ono K, Tanaka T, Tsunoda T, et al : Identification by cDNA microarray of genes involved in ovarian carcinogenesis. Cancer Res 60: 5007-5011, 2000.
27. Shridhar V, Sen A, Chien J, et al : Identification of underexpressed genes in early- and late-stage primary ovarian tumors by suppression subtraction hybridization. Cancer Res 62: 262-270, 2002. (Pubitemid 34074013)
28. Shridhar V, Lee J, Pandita A, et al: Genetic analysis of early-versus late-stage ovarian tumors. Cancer Res 61: 5895-5904, 2001. (Pubitemid 32769109)
29. Welsh JB, Zarrinkar PP, Sapinoso LM, et al: Analysis of gene expression profiles in normal and neoplastic ovarian tissue samples identifies candidate molecular markers of epithelial ovarian cancer. Proc Natl Acad Sci USA 98: 1176-1181, 2001. (Pubitemid 32121206)
30. Tonin PN, Hudson TJ, Rodier F, et al: Microarray analysis of gene expression mirrors the biology of an ovarian cancer model. Oncogene 20: 6617-6626, 2001. (Pubitemid 32980288)
31. Jazaeri AA, Yee CJ, Sotiriou C, Brantley KR, Boyd J and Liu ET: Gene expression profiles of BRCA1-linked, BRCA2-linked, and sporadic ovarian cancers. J Natl Cancer Inst 94: 990-1000, 2002. (Pubitemid 34814728)
32. Wang K, Gan L, Jeffery E, et al: Monitoring gene expression profile changes in ovarian carcinomas using cDNA microarray. Gene 229: 101-108, 1999. (Pubitemid 29148312)
33. Zorn KK, Jazaeri AA, Awtrey CS, et al : Choice of normal ovarian control influences determination of differentially expressed genes in ovarian cancer expression profiling studies. Clin Cancer Res 9: 4811-4818, 2003. (Pubitemid 37323284)
34. Saghizadeh M, Brown DJ, Tajbakhsh J, et al : Evaluation of techniques using amplified nucleic acid probes for gene expression profiling. Biomol Eng 20: 97-106, 2003. (Pubitemid 36398218)
35. Rudnicki M, Eder S, Schratzberger G, et al: Reliability of t7-based mRNA linear amplification validated by gene expression analysis of human kidney cells using cDNA microarrays. Nephron Exp Nephrol 97: E86-E95, 2004.
36. Nash MA, Deavers MT and Freedman RS: The expression of decorin in human ovarian tumors. Clin Cancer Res 8: 1754-1760, 2002. (Pubitemid 34633731)
37. Mauviel A, Santra M, Chen YQ, Uitto J and Iozzo RV: Transcriptional regulation of decorin gene expression. Induction by quiescence and repression by tumor necrosis factor-alpha. J Biol Chem 270: 11692-11700, 1995.
38. Grant DS, Yenisey C, Rose RW, Tootell M, Santra M and Iozzo RV: Decorin suppresses tumor cell-mediated angiogenesis. Oncogene 21: 4765-4777, 2002. (Pubitemid 34879452)
39. Chapman SC and Woodruff TK: Modulation of activin signal transduction by inhibin B and inhibin-binding protein (INhBP). Mol Endocrinol 15: 668-679, 2001. (Pubitemid 32324446)
40. Woodruff TK: Regulation of cellular and system function by activin. Biochem Pharmacol 55: 953-963, 1998.
41. Eramaa M, Heikinheimo K, Tuuri T, Hilden K and Ritvos O: Inhibin/activin subunit mRNA expression in human granulosa-luteal cells. Mol Cell Endocrinol 92: R15-R20, 1993. (Pubitemid 23124974)
42. Welt CK, Lambert-Messerlian G, Zheng W, Crowley WF, Jr. and Schneyer AL: Presence of activin, inhibin, and follistatin in epithelial ovarian carcinoma. J Clin Endocrinol Metab 82: 3720-3727, 1997. (Pubitemid 27509361)
43. Choi KC, Kang SK, Tai CJ, Auersperg N and Leung PC: The regulation of apoptosis by activin and transforming growth factor-beta in early neoplastic and tumorigenic ovarian surface epithelium. J Clin Endocrinol Metab 86: 2125-2135, 2001. (Pubitemid 32472930)