Advancing pharmacometrics and systems pharmacology

Clinical Pharmacology and Therapeutics

Volumn 92, Issue 5, 2012, Pages 535-537

  Waldman, S A ^a   Terzic, A ^b  

^a THOMAS JEFFERSON UNIVERSITY   (United States)

^b MAYO CLINIC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CLINICAL PHARMACOLOGY; CONCENTRATION RESPONSE; DRUG RESEARCH; DRUG TARGETING; MOLECULAR BIOLOGY; PHARMACODYNAMICS; PHARMACOLOGICAL SCIENCE; PHARMACOMETRICS; PRIORITY JOURNAL; QUALITATIVE ANALYSIS; QUANTITATIVE ANALYSIS; REVIEW; SYSTEMS BIOLOGY;

COOPERATIVE BEHAVIOR; DRUG DESIGN; HUMANS; PERIODICALS AS TOPIC; PHARMACOLOGY; PHARMACOLOGY, CLINICAL; PUBLISHING; SOCIETIES, PHARMACEUTICAL; UNITED STATES;

EID: 84867790487     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2012.151     Document Type: Review

References (12)

1. Atkinson, A.J., Jr. & Lyster, P.M. Systems clinical pharmacology. Clin. Pharmacol. Ther. 88, 3-6 (2010).
2. Atkinson, A.J., Jr. & Smith, B.P. Models of physiology and physiologically based models in clinical pharmacology. Clin. Pharmacol. Ther. 92, 3-6 (2012).
3. Grasela, T.H. & Slusser, R. Improving productivity with model-based drug development: an enterprise perspective. Clin. Pharmacol. Ther. 88, 263-268 (2010).
4. Kohl, P., Crampin, E.J., Quinn, T.A. & Noble, D. Systems biology: an approach. Clin. Pharmacol. Ther. 88, 25-33 (2010).
5. Arrell, D.K. & Terzic, A. Network systems biology for drug discovery. Clin. Pharmacol. Ther. 88, 120-125 (2010).
6. Rodriguez, B., Burrage, K., Gavaghan, D., Grau, V., Kohl, P. & Noble, D. The systems biology approach to drug development: application to toxicity assessment of cardiac drugs. Clin. Pharmacol. Ther. 88, 130-134 (2010).
7. Allerheiligen, S.R. Next-generation model-based drug discovery and development: quantitative and systems pharmacology. Clin. Pharmacol. Ther. 88, 135-137 (2010).
8. Dollery, C.T. The challenge of complexity. Clin. Pharmacol. Ther. 88, 13-15 (2010).
9. Vicini, P. Multiscale modeling in drug discovery and development: future opportunities and present challenges. Clin. Pharmacol. Ther. 88, 126-129 (2010).
10. Yang, R., Niepel, M., Mitchison, T.K. & Sorger, P.K. Dissecting variability in responses to cancer chemotherapy through systems pharmacology. Clin. Pharmacol. Ther. 88, 34-38 (2010).
11. Waldman, S.A. & Terzic, A. Molecular therapeutics from knowledge to delivery. Clin. Pharmacol. Ther. 87, 619-623 (2010).
12. van der Graaf, P.H. CPT: Pharmacometrics and Systems Pharmacology. CPT Pharmacometrics Syst. Pharmacol. 1, e8 (2012).