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Volumn 88, Issue 1, 2010, Pages 3-6

Editorial: Systems clinical pharmacology

Author keywords

[No Author keywords available]

Indexed keywords

DRUG; BIOLOGICAL MARKER;

EID: 77953743760     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1038/clpt.2010.88     Document Type: Editorial
Times cited : (12)

References (20)
  • 1
    • 43049145199 scopus 로고    scopus 로고
    • Academy of Medical Sciences and The Royal Academy of Engineering Working Group
    • Academy of Medical Sciences and The Royal Academy of Engineering Working Group. Systems Biology: A Vision for Engineering and Medicine http://www3. imperial.ac.uk/pls/portallive/docs/1/23357696.pdf.
    • Systems Biology: A Vision for Engineering and Medicine
  • 2
    • 77953811662 scopus 로고    scopus 로고
    • Network systems biology for drug discovery
    • Arrell, D.K. & Terzic, A. Network systems biology for drug discovery. Clin. Pharmacol. Ther. 88, 120-125 (2010).
    • (2010) Clin. Pharmacol. Ther. , vol.88 , pp. 120-125
    • Arrell, D.K.1    Terzic, A.2
  • 4
    • 31144438390 scopus 로고    scopus 로고
    • Rescuing drug discovery: In vivo systems pathology and systems pharmacology
    • Van der Greef, J. & McBurney, R.N. Rescuing drug discovery: in vivo systems pathology and systems pharmacology. Nat. Rev. Drug Discov. 4, 961-967 (2005).
    • (2005) Nat. Rev. Drug Discov. , vol.4 , pp. 961-967
    • Van Der Greef, J.1    McBurney, R.N.2
  • 5
    • 0003100554 scopus 로고
    • Robustness in the strategy of scientific model building
    • eds. Launer, R.L. & Wilkinson, G.N. Academic Press, New York
    • Box, G.E.P. Robustness in the strategy of scientific model building. In Robustness in Statistics (eds. Launer, R.L. & Wilkinson, G.N.) 231-236 (Academic Press, New York, 1979).
    • (1979) Robustness in Statistics , pp. 231-236
    • Box, G.E.P.1
  • 6
  • 7
    • 0000999661 scopus 로고
    • The formulation and testing of models
    • Berman, M. The formulation and testing of models. Ann. NY Acad. Sci. 108, 182-194 (1963).
    • (1963) Ann. NY Acad. Sci. , vol.108 , pp. 182-194
    • Berman, M.1
  • 8
    • 77953785687 scopus 로고    scopus 로고
    • The challenge of complexity
    • Dollery, C.T. The challenge of complexity. Clin. Pharmacol. Ther. 88, 13-15 (2010).
    • (2010) Clin. Pharmacol. Ther. , vol.88 , pp. 13-15
    • Dollery, C.T.1
  • 9
    • 77953806651 scopus 로고    scopus 로고
    • Multiscale modeling in drug discovery and development: Future opportunities and present challenges
    • Vicini, P. Multiscale modeling in drug discovery and development: future opportunities and present challenges. Clin. Pharmacol. Ther. 88, 126-129 (2010).
    • (2010) Clin. Pharmacol. Ther. , vol.88 , pp. 126-129
    • Vicini, P.1
  • 10
    • 67649392513 scopus 로고    scopus 로고
    • A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry biology anatomy physiology and genetics: A tale of "bottom-up" vs. "top-down" recognition of covariates
    • Jamei, M. Dickinson, G.L. & Rostami-Hodjegan, A. A framework for assessing inter-individual variability in pharmacokinetics using virtual human populations and integrating general knowledge of physical chemistry, biology, anatomy, physiology and genetics: a tale of "bottom-up" vs. "top-down" recognition of covariates. Drug Metab. Pharmacokinet. 24, 53-75 (2009).
    • (2009) Drug Metab. Pharmacokinet. , vol.24 , pp. 53-75
    • Jamei, M.1    Dickinson, G.L.2    Rostami-Hodjegan, A.3
  • 11
    • 77953811461 scopus 로고    scopus 로고
    • The systems biology approach to drug development: Application to toxicity assessment of cardiac drugs
    • Rodriguez, B., Burrage, K., Gavaghan, D., Grau, V., Kohl, P. & Noble, D. The systems biology approach to drug development: application to toxicity assessment of cardiac drugs. Clin. Pharmacol. Ther. 88, 130-134 (2010).
    • (2010) Clin. Pharmacol. Ther. , vol.88 , pp. 130-134
    • Rodriguez, B.1    Burrage, K.2    Gavaghan, D.3    Grau, V.4    Kohl, P.5    Noble, D.6
  • 12
    • 62749161471 scopus 로고    scopus 로고
    • The liver toxicity biomarker study: Phase i design and preliminary results
    • McBurney, R.N. et al. The liver toxicity biomarker study: phase I design and preliminary results. Toxicol. Pathol. 37, 52-64 (2009).
    • (2009) Toxicol. Pathol. , vol.37 , pp. 52-64
    • McBurney, R.N.1
  • 13
    • 39449120417 scopus 로고    scopus 로고
    • Correlation network analysis for data integration and biomarker selection
    • Adourian, A., et al. Correlation network analysis for data integration and biomarker selection. Mol. BioSyst. 4, 249-259 (2008).
    • (2008) Mol. BioSyst. , vol.4 , pp. 249-259
    • Adourian, A.1
  • 15
    • 5044229321 scopus 로고    scopus 로고
    • The impact of systems approaches on biological problems in drug discovery
    • Hood, L. & Perlmutter, M. The impact of systems approaches on biological problems in drug discovery. Nat. Biotechnol. 22,1215-1217 (2004).
    • (2004) Nat. Biotechnol. , vol.22 , pp. 1215-1217
    • Hood, L.1    Perlmutter, M.2
  • 16
    • 35449004951 scopus 로고    scopus 로고
    • Molecular systems biology in drug development
    • Silver, P.A. & Way, J.C. Molecular systems biology in drug development. Clin. Pharmacol. Ther. 82, 586-590 (2007).
    • (2007) Clin. Pharmacol. Ther. , vol.82 , pp. 586-590
    • Silver, P.A.1    Way, J.C.2
  • 19
    • 77953790081 scopus 로고    scopus 로고
    • Training in systems pharmacology: Predoctoral program in pharmacology and systems biology at Mount Sinai School of Medicine
    • Sobie, E.A., Jenkins, S.L., Iyengar, R. & Krulwich, T.A. Training in systems pharmacology: predoctoral program in pharmacology and systems biology at Mount Sinai School of Medicine. Clin. Pharmacol. Ther. 88, 19-22 (2010).
    • (2010) Clin. Pharmacol. Ther. , vol.88 , pp. 19-22
    • Sobie, E.A.1    Jenkins, S.L.2    Iyengar, R.3    Krulwich, T.A.4
  • 20
    • 77953809572 scopus 로고    scopus 로고
    • Next-generation model-based drug discovery and development: Quantitative and systems pharmacology
    • Allerheiligen, S.R.B. Next-generation model-based drug discovery and development: quantitative and systems pharmacology. Clin. Pharmacol. Ther. 88, 135-137 (2010).
    • (2010) Clin. Pharmacol. Ther. , vol.88 , pp. 135-137
    • Allerheiligen, S.R.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.