Ondansetron and granisetron binding orientation in the 5-HT3 receptor determined by unnatural amino acid mutagenesis

ACS Chemical Biology

Volumn 7, Issue 10, 2012, Pages 1738-1745

  Duffy, Noah H ^a   Lester, Henry A ^b   Dougherty, Dennis A ^a  

^a California Institute of Technology   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATION; GRANISETRON; ONDANSETRON; SEROTONIN 3A RECEPTOR; TRYPTOPHAN; SEROTONIN; SEROTONIN 3 RECEPTOR; SEROTONIN AGONIST; SEROTONIN ANTAGONIST;

ARTICLE; BINDING SITE; CONTROLLED STUDY; DOSE RESPONSE; DRUG RECEPTOR BINDING; LIGAND BINDING; MUTAGENESIS; NONHUMAN; OOCYTE; PHARMACOPHORE; PRIORITY JOURNAL; PROTEIN EXPRESSION; XENOPUS LAEVIS; ANIMAL; BINDING COMPETITION; CHEMICAL STRUCTURE; CHEMISTRY; GENETICS; METABOLISM; MOUSE; POINT MUTATION;

ANIMALS; BINDING, COMPETITIVE; GRANISETRON; MICE; MODELS, MOLECULAR; ONDANSETRON; OOCYTES; POINT MUTATION; RECEPTORS, SEROTONIN, 5-HT3; SEROTONIN; SEROTONIN ANTAGONISTS; SEROTONIN RECEPTOR AGONISTS; XENOPUS LAEVIS;

EID: 84867757238     PISSN: 15548929     EISSN: 15548937     Source Type: Journal    
DOI: 10.1021/cb300246j     Document Type: Article

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