메뉴 건너뛰기




Volumn 110, Issue 9, 2012, Pages 1289-1300

Recent advances in the treatment of advanced renal cell carcinoma: Towards multidisciplinary personalized care

Author keywords

biomarkers; multidisciplinary care; RCC; renal cell carcinoma; targeted therapy

Indexed keywords

ALPHA INTERFERON; AXITINIB; BEVACIZUMAB; EVEROLIMUS; PAZOPANIB; PLACEBO; PROTEIN TYROSINE KINASE INHIBITOR; SORAFENIB; SUNITINIB; TEMSIROLIMUS; TIVOZANIB; TUMOR MARKER; VASCULOTROPIN RECEPTOR 3;

EID: 84867742783     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2012.11100.x     Document Type: Article
Times cited : (12)

References (88)
  • 3
    • 33846224397 scopus 로고    scopus 로고
    • The follow-up management of non-metastatic renal cell carcinoma: Definition of a surveillance protocol
    • Antonelli A, Cozzoli A, Zani D, et al,. The follow-up management of non-metastatic renal cell carcinoma: definition of a surveillance protocol. BJU Int 2007; 99: 296-300
    • (2007) BJU Int , vol.99 , pp. 296-300
    • Antonelli, A.1    Cozzoli, A.2    Zani, D.3
  • 4
    • 44949144092 scopus 로고    scopus 로고
    • Targeted therapy for advanced renal cell carcinoma
    • Coppin C, Le L, Porzsolt F, et al,. Targeted therapy for advanced renal cell carcinoma. Cochrane Database Syst Rev 2008; (4:2): CD006017
    • (2008) Cochrane Database Syst Rev , vol.4 , Issue.2
    • Coppin, C.1    Le, L.2    Porzsolt, F.3
  • 5
    • 77954326508 scopus 로고    scopus 로고
    • Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up
    • Escudier B, Kataja V,. Renal cell carcinoma: ESMO Clinical Practice Guidelines for diagnosis, treatment and follow-up. Ann Oncol 2010; 21 (Suppl. 5): v137-v139
    • (2010) Ann Oncol , vol.21 , Issue.5 SUPPL.
    • Escudier, B.1    Kataja, V.2
  • 6
    • 84892145621 scopus 로고    scopus 로고
    • Guidelines on renal cell carcinoma
    • Available at:. Accessed March 2012
    • Ljungberg B, Cowan N, Hanbury DC, et al,. Guidelines on renal cell carcinoma. Eur Ass Urol 2010. Available at: http://www.uroweb.org/?id= 218&gid=4. Accessed March 2012
    • (2010) Eur Ass Urol.
    • Ljungberg, B.1    Cowan, N.2    Hanbury, D.C.3
  • 7
    • 34247516968 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network. Available at: Accessed March 2012
    • National Comprehensive Cancer Network. NCCN clinical practice guidelines in oncology: kidney cancer v.2. 2010. Available at: http://www.nccn.org/ professionals/physician-gls/f-guidelines.asp. Accessed March 2012
    • (2010) NCCN Clinical Practice Guidelines in Oncology: Kidney Cancer V.2
  • 8
    • 84872611380 scopus 로고    scopus 로고
    • Available at:. Accessed 17 November 2011
    • ClinicalTrials.gov. Search term: axitinib. 2011. Available at: http://www.clinicaltrials.gov/ct2/results?term=axitinib. Accessed 17 November 2011
    • (2011) Search term: axitinib
  • 9
    • 84872599568 scopus 로고    scopus 로고
    • Available at: Accessed 17 November 2011
    • ClinicalTrials.gov. Search term: tivozanib. 2011. Available at: http://www.clinicaltrials.gov/ct2/results?term=tivozanib. Accessed 17 November 2011
    • (2011) Search Term: Tivozanib
  • 10
    • 70249097380 scopus 로고    scopus 로고
    • Sorafenib for treatment of renal cell carcinoma: Final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial
    • Escudier B, Eisen T, Stadler WM, et al,. Sorafenib for treatment of renal cell carcinoma: final efficacy and safety results of the phase III treatment approaches in renal cancer global evaluation trial. J Clin Oncol 2009; 27: 3312-8
    • (2009) J Clin Oncol , vol.27 , pp. 3312-3318
    • Escudier, B.1    Eisen, T.2    Stadler, W.M.3
  • 11
    • 77952300540 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab plus Interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): Final analysis of overall survival
    • Escudier B, Bellmunt J, Negrier S, et al,. Phase III trial of bevacizumab plus Interferon alfa-2a in patients with metastatic renal cell carcinoma (AVOREN): final analysis of overall survival. J Clin Oncol 2010; 28: 2144-50
    • (2010) J Clin Oncol , vol.28 , pp. 2144-2150
    • Escudier, B.1    Bellmunt, J.2    Negrier, S.3
  • 12
    • 34249779568 scopus 로고    scopus 로고
    • Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma
    • Hudes G, Carducci M, Tomczak P, et al,. Temsirolimus, interferon alfa, or both for advanced renal-cell carcinoma. N Engl J Med 2007; 356: 2271-81
    • (2007) N Engl J Med , vol.356 , pp. 2271-2281
    • Hudes, G.1    Carducci, M.2    Tomczak, P.3
  • 13
    • 68949145218 scopus 로고    scopus 로고
    • Overall survival and updated results for sunitinib versus interferon alfa in first-line treatment of patients with metastatic renal cell carcinoma
    • Motzer RJ, Hutson TE, Tomczak P, et al,. Overall survival and updated results for sunitinib versus interferon alfa in first-line treatment of patients with metastatic renal cell carcinoma. J Clin Oncol 2009; 27: 3584-90
    • (2009) J Clin Oncol , vol.27 , pp. 3584-3590
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 14
    • 77956227464 scopus 로고    scopus 로고
    • Phase 3 trial of everolimus for metastatic renal cell carcinoma: Final results and analysis of prognostic factors
    • Motzer RJ, Escudier B, Oudard S, et al,. Phase 3 trial of everolimus for metastatic renal cell carcinoma: final results and analysis of prognostic factors. Cancer 2010; 116: 4256-65
    • (2010) Cancer , vol.116 , pp. 4256-4265
    • Motzer, R.J.1    Escudier, B.2    Oudard, S.3
  • 15
    • 77952318310 scopus 로고    scopus 로고
    • Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: Final results of CALGB 90206
    • Rini BI, Halabi S, Rosenberg JE, et al,. Phase III trial of bevacizumab plus interferon alfa versus interferon alfa monotherapy in patients with metastatic renal cell carcinoma: final results of CALGB 90206. J Clin Oncol 2010; 28: 2137-43
    • (2010) J Clin Oncol , vol.28 , pp. 2137-2143
    • Rini, B.I.1    Halabi, S.2    Rosenberg, J.E.3
  • 16
    • 77949890945 scopus 로고    scopus 로고
    • Pazopanib in locally advanced or metastatic renal cell carcinoma: Results of a randomized phase III trial
    • Sternberg CN, Davis ID, Mardiak J, et al,. Pazopanib in locally advanced or metastatic renal cell carcinoma: results of a randomized phase III trial. J Clin Oncol 2010; 28: 1061-8
    • (2010) J Clin Oncol , vol.28 , pp. 1061-1068
    • Sternberg, C.N.1    Davis, I.D.2    Mardiak, J.3
  • 18
    • 56749161699 scopus 로고    scopus 로고
    • Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206
    • Rini BI, Halabi S, Rosenberg JE, et al,. Bevacizumab plus interferon alfa compared with interferon alfa monotherapy in patients with metastatic renal cell carcinoma: CALGB 90206. J Clin Oncol 2008; 26: 5422-8
    • (2008) J Clin Oncol , vol.26 , pp. 5422-5428
    • Rini, B.I.1    Halabi, S.2    Rosenberg, J.E.3
  • 19
    • 37349080670 scopus 로고    scopus 로고
    • Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: A randomised, double-blind phase III trial
    • Escudier B, Pluzanska A, Koralewski P, et al,. Bevacizumab plus interferon alfa-2a for treatment of metastatic renal cell carcinoma: a randomised, double-blind phase III trial. Lancet 2007; 370: 2103-11
    • (2007) Lancet , vol.370 , pp. 2103-2111
    • Escudier, B.1    Pluzanska, A.2    Koralewski, P.3
  • 20
    • 33846181370 scopus 로고    scopus 로고
    • Sunitinib versus interferon alfa in metastatic renal-cell carcinoma
    • Motzer RJ, Hutson TE, Tomczak P, et al,. Sunitinib versus interferon alfa in metastatic renal-cell carcinoma. N Engl J Med 2007; 356: 115-24
    • (2007) N Engl J Med , vol.356 , pp. 115-124
    • Motzer, R.J.1    Hutson, T.E.2    Tomczak, P.3
  • 21
    • 50649099256 scopus 로고    scopus 로고
    • Clinical effect and future considerations for molecularly-targeted therapy in renal cell carcinoma
    • Rini BI, Flaherty K,. Clinical effect and future considerations for molecularly-targeted therapy in renal cell carcinoma. Urol Oncol 2008; 26: 543-9
    • (2008) Urol Oncol , vol.26 , pp. 543-549
    • Rini, B.I.1    Flaherty, K.2
  • 22
    • 70349385645 scopus 로고    scopus 로고
    • Resistance to targeted therapy in renal-cell carcinoma
    • Rini BI, Atkins MB,. Resistance to targeted therapy in renal-cell carcinoma. Lancet Oncol 2009; 10: 992-1000
    • (2009) Lancet Oncol , vol.10 , pp. 992-1000
    • Rini, B.I.1    Atkins, M.B.2
  • 23
    • 77956040624 scopus 로고    scopus 로고
    • Is advanced renal cell carcinoma becoming a chronic disease?
    • Larkin J, Gore M,. Is advanced renal cell carcinoma becoming a chronic disease? Lancet 2010; 376: 574-5
    • (2010) Lancet , vol.376 , pp. 574-575
    • Larkin, J.1    Gore, M.2
  • 24
    • 70349388719 scopus 로고    scopus 로고
    • Phase II study of axitinib in sorafenib-refractory metastatic renal cell carcinoma
    • Rini BI, Wilding G, Hudes G, et al,. Phase II study of axitinib in sorafenib-refractory metastatic renal cell carcinoma. J Clin Oncol 2009; 27: 4462-8
    • (2009) J Clin Oncol , vol.27 , pp. 4462-4468
    • Rini, B.I.1    Wilding, G.2    Hudes, G.3
  • 25
    • 80052225008 scopus 로고    scopus 로고
    • Axitinib versus sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC): Results of phase III AXIS trial
    • (Suppl.) 4503
    • Rini BI, Escudier B, Tomczak P, et al,. Axitinib versus sorafenib as second-line therapy for metastatic renal cell carcinoma (mRCC): results of phase III AXIS trial. J Clin Oncol 2011; 29 (Suppl.): Abstract 4503
    • (2011) J Clin Oncol , vol.29
    • Rini, B.I.1    Escudier, B.2    Tomczak, P.3
  • 26
    • 77955470097 scopus 로고    scopus 로고
    • Clinical outcome in metastatic renal cell carcinoma patients after failure of initial vascular endothelial growth factor-targeted therapy
    • Vickers MM, Choueiri TK, Rogers M, et al,. Clinical outcome in metastatic renal cell carcinoma patients after failure of initial vascular endothelial growth factor-targeted therapy. Urology 2010; 76: 430-4
    • (2010) Urology , vol.76 , pp. 430-434
    • Vickers, M.M.1    Choueiri, T.K.2    Rogers, M.3
  • 27
    • 84872609309 scopus 로고    scopus 로고
    • Sequential use of temsirolimus (TEM) in patients with metastatic renal cell carcinoma (mRCC): Safety and efficacy following failure of receptor tyrosine kinase inhibitor (TKI) treatment
    • Abstract 95
    • Weikert S, Kempkensteffen C, Zimmerman K, et al,. Sequential use of temsirolimus (TEM) in patients with metastatic renal cell carcinoma (mRCC): safety and efficacy following failure of receptor tyrosine kinase inhibitor (TKI) treatment. 25th Annual European Association of Urology Congress. 2010, Abstract 95
    • (2010) 25th Annual European Association of Urology Congress
    • Weikert, S.1    Kempkensteffen, C.2    Zimmerman, K.3
  • 28
    • 78751477225 scopus 로고    scopus 로고
    • More than 4 years of progression-free survival in a patient with metastatic renal cell carcinoma treated sequentially with sunitinib, everolimus, sorafenib, and temsirolimus
    • Oudard S,. More than 4 years of progression-free survival in a patient with metastatic renal cell carcinoma treated sequentially with sunitinib, everolimus, sorafenib, and temsirolimus. Anticancer Res 2010; 30: 5223-5
    • (2010) Anticancer Res , vol.30 , pp. 5223-5225
    • Oudard, S.1
  • 29
    • 79551592461 scopus 로고    scopus 로고
    • Clinical activity of sunitinib rechallenge in metastatic renal cell carcinoma
    • Available at: Accessed March 2012. (Abstract 319)
    • Rini BI, Hutson TE, Elson P, et al,. Clinical activity of sunitinib rechallenge in metastatic renal cell carcinoma. 2010. Available at: http://www.asco.org/ASCOv2/Meetings/Abstracts?&vmview=abst-detail- view&confID=73&abstractID=30062. Accessed March 2012. ASCO 2010 Genitourinary Cancers Symposium (Abstract 319)
    • (2010) ASCO 2010 Genitourinary Cancers Symposium
    • Rini, B.I.1    Hutson, T.E.2    Elson, P.3
  • 33
  • 38
    • 78650027911 scopus 로고    scopus 로고
    • The impact of cytoreductive nephrectomy on survival of patients with metastatic renal cell carcinoma receiving vascular endothelial growth factor targeted therapy
    • Choueiri TK, Xie W, Kollmannsberger C, et al,. The impact of cytoreductive nephrectomy on survival of patients with metastatic renal cell carcinoma receiving vascular endothelial growth factor targeted therapy. J Urol 2011; 185: 60-6
    • (2011) J Urol , vol.185 , pp. 60-66
    • Choueiri, T.K.1    Xie, W.2    Kollmannsberger, C.3
  • 39
    • 84957673525 scopus 로고    scopus 로고
    • Exploratory analysis of the influence of nephrectomy status on temsirolimus efficacy in patients with advanced renal cell carcinoma and poor-risk features
    • Abstract 281
    • Logan T, McDermott D, Dutcher J, et al,. Exploratory analysis of the influence of nephrectomy status on temsirolimus efficacy in patients with advanced renal cell carcinoma and poor-risk features. American Society for Clinical Oncology 2009 Genitourinary Cancers Symposium 2009; Abstract 281
    • (2009) American Society for Clinical Oncology 2009 Genitourinary Cancers Symposium
    • Logan, T.1    McDermott, D.2    Dutcher, J.3
  • 42
    • 78650246687 scopus 로고    scopus 로고
    • Primary tumor response to targeted agents in patients with metastatic renal cell carcinoma
    • Abel EJ, Culp SH, Tannir NM, et al,. Primary tumor response to targeted agents in patients with metastatic renal cell carcinoma. Eur Urol 2011; 59: 10-5
    • (2011) Eur Urol , vol.59 , pp. 10-15
    • Abel, E.J.1    Culp, S.H.2    Tannir, N.M.3
  • 43
    • 78049484272 scopus 로고    scopus 로고
    • Integrating surgery with targeted therapies for renal cell carcinoma: Current evidence and ongoing trials
    • Bex A, Jonasch E, Kirkali Z, et al,. Integrating surgery with targeted therapies for renal cell carcinoma: current evidence and ongoing trials. Eur Urol 2010; 58: 819-28
    • (2010) Eur Urol , vol.58 , pp. 819-828
    • Bex, A.1    Jonasch, E.2    Kirkali, Z.3
  • 44
    • 77956642234 scopus 로고    scopus 로고
    • Prospective clinical trial of preoperative sunitinib in patients with renal cell carcinoma
    • Hellenthal NJ, Underwood W, Penetrante R, et al,. Prospective clinical trial of preoperative sunitinib in patients with renal cell carcinoma. J Urol 2010; 184: 859-64
    • (2010) J Urol , vol.184 , pp. 859-864
    • Hellenthal, N.J.1    Underwood, W.2    Penetrante, R.3
  • 45
    • 84872612729 scopus 로고    scopus 로고
    • ClinicalTrials.gov Accessed 17 November 2011
    • ClinicalTrials.gov. A phase II study of pazopanib to enable partial nephrectomy. 2011. Available at: http://www.clinicaltrials.gov/ct2/show/ NCT01158521?term=NCT01158521&rank=1. Accessed 17 November 2011
    • (2011) A phase II study of pazopanib to enable partial nephrectomy
  • 51
    • 84872599274 scopus 로고    scopus 로고
    • January 2011 Accessed March 2012
    • Pfizer I. SUTENT. Summary of product characteristics; January 2011. 2011. Available at: http://www.medicines.org.uk/EMC/medicine/18531/SPC/SUTENT+12. 5mg%2c+25mg%2c+37.5mg+and+50mg+Hard+Capsules/. Accessed March 2012
    • (2011) Pfizer I. SUTENT. Summary of product characteristics
  • 52
    • 77952118055 scopus 로고    scopus 로고
    • Bayer Heathcare AG December 2010 Accessed March 2012
    • Bayer Heathcare AG. Sorafenib, summary of product characteristics; December 2010. 2010. Available at: http://www.medicines.org.uk/EMC/medicine/ 18520/SPC/Nexavar+200mg+film-coated+tablets/. Accessed March 2012
    • (2010) Sorafenib, summary of product characteristics
  • 53
    • 77953645348 scopus 로고    scopus 로고
    • Roche Products Ltd. January 2011 Accessed March 2012
    • Roche Products Ltd. Avastin, summary of product characteristics; January 2011. 2011. Available at: http://www.medicines.org.uk/EMC/medicine/15748/SPC/ Avastin+25mg+ml+concentrate+for+solution+for+infusion/. Accessed March 2012
    • (2011) Avastin, summary of product characteristics
  • 54
    • 84872606503 scopus 로고    scopus 로고
    • GlaxoSmithKline June 2010 Accessed March 2012
    • pazopanib), Summary of product characteristics; June 2010. 2011. Available at: http://www.medicines.org.uk/EMC/ medicine/23148/SPC/Votrient+200+mg+and+400+mg+film+coated+tablets/. Accessed March 2012
    • (2011) pazopanib), Summary of product characteristics
  • 55
    • 79955512251 scopus 로고    scopus 로고
    • The safety and efficacy of sunitinib before planned nephrectomy in metastatic clear cell renal cancer
    • Powles T, Kayani I, Blank C, et al,. The safety and efficacy of sunitinib before planned nephrectomy in metastatic clear cell renal cancer. Ann Oncol 2011; 5: 1041-7
    • (2011) Ann Oncol , vol.5 , pp. 1041-1047
    • Powles, T.1    Kayani, I.2    Blank, C.3
  • 56
    • 70249115638 scopus 로고    scopus 로고
    • Phase II presurgical feasibility study of bevacizumab in untreated patients with metastatic renal cell carcinoma
    • Jonasch E, Wood CG, Matin SF, et al,. Phase II presurgical feasibility study of bevacizumab in untreated patients with metastatic renal cell carcinoma. J Clin Oncol 2009; 27: 4076-81
    • (2009) J Clin Oncol , vol.27 , pp. 4076-4081
    • Jonasch, E.1    Wood, C.G.2    Matin, S.F.3
  • 57
    • 79959316184 scopus 로고    scopus 로고
    • Pazopanib efficacy in renal cell carcinoma: Evidence for predictive genetic markers in angiogenesis-related and exposure-related genes
    • Xu CF, Bing NX, Ball HA, et al,. Pazopanib efficacy in renal cell carcinoma: evidence for predictive genetic markers in angiogenesis-related and exposure-related genes. J Clin Oncol 2011; 29: 2557-64
    • (2011) J Clin Oncol , vol.29 , pp. 2557-2564
    • Xu, C.F.1    Bing, N.X.2    Ball, H.A.3
  • 59
    • 67651056360 scopus 로고    scopus 로고
    • Effect of temsirolimus versus interferon-alpha on outcome of patients with advanced renal cell carcinoma of different tumor histologies
    • Dutcher JP, de SP, McDermott D, et al,. Effect of temsirolimus versus interferon-alpha on outcome of patients with advanced renal cell carcinoma of different tumor histologies. Med Oncol 2009; 26: 202-9
    • (2009) Med Oncol , vol.26 , pp. 202-209
    • Dutcher, J.P.1    De, S.P.2    McDermott, D.3
  • 60
    • 67651201656 scopus 로고    scopus 로고
    • Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: An expanded-access trial
    • Gore ME, Szczylik C, Porta C, et al,. Safety and efficacy of sunitinib for metastatic renal-cell carcinoma: an expanded-access trial. Lancet Oncol 2009; 10: 757-63
    • (2009) Lancet Oncol , vol.10 , pp. 757-763
    • Gore, M.E.1    Szczylik, C.2    Porta, C.3
  • 61
    • 77149126422 scopus 로고    scopus 로고
    • Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America
    • Stadler WM, Figlin RA, McDermott DF, et al,. Safety and efficacy results of the advanced renal cell carcinoma sorafenib expanded access program in North America. Cancer 2010; 116: 1272-80
    • (2010) Cancer , vol.116 , pp. 1272-1280
    • Stadler, W.M.1    Figlin, R.A.2    McDermott, D.F.3
  • 63
    • 79955463086 scopus 로고    scopus 로고
    • VEGF polymorphisms are associated with an increasing risk of developing renal cell carcinoma
    • Bruyere F, Hovens CM, Marson MN, et al,. VEGF polymorphisms are associated with an increasing risk of developing renal cell carcinoma. J Urol 2010; 184: 1273-8
    • (2010) J Urol , vol.184 , pp. 1273-1278
    • Bruyere, F.1    Hovens, C.M.2    Marson, M.N.3
  • 64
    • 77957785159 scopus 로고    scopus 로고
    • Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma
    • Lin J, Horikawa Y, Tamboli P, Clague J, Wood CG, Wu X,. Genetic variations in microRNA-related genes are associated with survival and recurrence in patients with renal cell carcinoma. Carcinogenesis 2010; 31: 1805-12
    • (2010) Carcinogenesis , vol.31 , pp. 1805-1812
    • Lin, J.1    Horikawa, Y.2    Tamboli, P.3    Clague, J.4    Wood, C.G.5    Wu, X.6
  • 65
    • 81255160848 scopus 로고    scopus 로고
    • Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: A multicentre, observational, prospective study
    • Garcia-Donas J, Esteban E, Leandro-Garcia LJ, et al,. Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study. Lancet Oncol 2011; 12: 1143-50
    • (2011) Lancet Oncol , vol.12 , pp. 1143-1150
    • Garcia-Donas, J.1    Esteban, E.2    Leandro-Garcia, L.J.3
  • 66
    • 74549209552 scopus 로고    scopus 로고
    • Upfront, randomized, phase 2 trial of sorafenib versus sorafenib and low-dose interferon alfa in patients with advanced renal cell carcinoma: Clinical and biomarker analysis
    • Jonasch E, Corn P, Pagliaro LC, et al,. Upfront, randomized, phase 2 trial of sorafenib versus sorafenib and low-dose interferon alfa in patients with advanced renal cell carcinoma: clinical and biomarker analysis. Cancer 2010; 116: 57-65
    • (2010) Cancer , vol.116 , pp. 57-65
    • Jonasch, E.1    Corn, P.2    Pagliaro, L.C.3
  • 67
    • 64549154074 scopus 로고    scopus 로고
    • Molecular signatures of localized clear cell renal cell carcinoma to predict disease-free survival after nephrectomy
    • Klatte T, Seligson DB, LaRochelle J, et al,. Molecular signatures of localized clear cell renal cell carcinoma to predict disease-free survival after nephrectomy. Cancer Epidemiol Biomarkers Prev 2009; 18: 894-900
    • (2009) Cancer Epidemiol Biomarkers Prev , vol.18 , pp. 894-900
    • Klatte, T.1    Seligson, D.B.2    Larochelle, J.3
  • 68
    • 76749116597 scopus 로고    scopus 로고
    • Small renal masses: Current concepts regarding the natural history and reflections on the American Urological Association guidelines
    • Mues AC, Landman J,. Small renal masses: current concepts regarding the natural history and reflections on the American Urological Association guidelines. Curr Opin Urol 2010; 20: 105-10
    • (2010) Curr Opin Urol , vol.20 , pp. 105-110
    • Mues, A.C.1    Landman, J.2
  • 69
    • 82355172847 scopus 로고    scopus 로고
    • Association of germ-line genetic markers in IL8, HIF1A, VEGFA, and VEGFR2 with treatment response to pazopanib in renal cell carcinoma
    • 4520
    • Ball HA, Xu C, Sternberg CN, et al,. Association of germ-line genetic markers in IL8, HIF1A, VEGFA, and VEGFR2 with treatment response to pazopanib in renal cell carcinoma. J Clin Oncol 2010; 28: Abstract 4520
    • (2010) J Clin Oncol , vol.28
    • Ball, H.A.1    Xu, C.2    Sternberg, C.N.3
  • 70
    • 79960364265 scopus 로고    scopus 로고
    • Use of a multiplatform analysis of plasma cytokines and angiogenic factors (CAFs) to identify baseline CAFs associated with pazopanib response and tumor burden in renal cell carcinoma (RCC) patients
    • 4522
    • Tran HT, Liu Y, Lin Y, et al,. Use of a multiplatform analysis of plasma cytokines and angiogenic factors (CAFs) to identify baseline CAFs associated with pazopanib response and tumor burden in renal cell carcinoma (RCC) patients. J Clin Oncol 2010; 28: Abstract 4522
    • (2010) J Clin Oncol , vol.28
    • Tran, H.T.1    Liu, Y.2    Lin, Y.3
  • 71
    • 77649125649 scopus 로고    scopus 로고
    • Diastolic blood pressure (dBP) and pharmacokinetics (PK) as predictors of axitinib efficacy in metastatic renal cell cancer (mRCC)
    • 5045
    • Rixe O, Dutcher J, Motzer R, et al,. Diastolic blood pressure (dBP) and pharmacokinetics (PK) as predictors of axitinib efficacy in metastatic renal cell cancer (mRCC). J Clin Oncol 2009; 25: Abstract 5045
    • (2009) J Clin Oncol , vol.25
    • Rixe, O.1    Dutcher, J.2    Motzer, R.3
  • 72
    • 77958063197 scopus 로고    scopus 로고
    • Hypertension (HTN) as a biomarker of efficacy in patients (pts) with metastatic renal cell carcinoma (mRCC) treated with sunitinib
    • Abstract 312
    • Rini BI, Cohen DP, Lu D, et al,. Hypertension (HTN) as a biomarker of efficacy in patients (pts) with metastatic renal cell carcinoma (mRCC) treated with sunitinib. American Socierty for Clinical Oncology 2010 Genitourinary Cancers Symposium 2010; Abstract 312
    • (2010) American Socierty for Clinical Oncology 2010 Genitourinary Cancers Symposium
    • Rini, B.I.1    Cohen, D.P.2    Lu, D.3
  • 73
    • 78651361788 scopus 로고    scopus 로고
    • Hypothyroidism in patients with renal cell carcinoma: Blessing or curse?
    • Schmidinger M, Vogl UM, Bojic M, et al,. Hypothyroidism in patients with renal cell carcinoma: blessing or curse? Cancer 2010; 117: 534-44
    • (2010) Cancer , vol.117 , pp. 534-544
    • Schmidinger, M.1    Vogl, U.M.2    Bojic, M.3
  • 74
    • 34247203754 scopus 로고    scopus 로고
    • The role of molecular markers in the staging of renal cell carcinoma
    • Leppert JT, Pantuck AJ, Figlin RA, Belldegrun AS,. The role of molecular markers in the staging of renal cell carcinoma. BJU Int 2000; 99: 1208-11
    • (2000) BJU Int , vol.99 , pp. 1208-1211
    • Leppert, J.T.1    Pantuck, A.J.2    Figlin, R.A.3    Belldegrun, A.S.4
  • 75
    • 0036138580 scopus 로고    scopus 로고
    • Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma
    • Motzer RJ, Bacik J, Murphy BA, Russo P, Mazumdar M,. Interferon-alfa as a comparative treatment for clinical trials of new therapies against advanced renal cell carcinoma. J Clin Oncol 2002; 20: 289-96
    • (2002) J Clin Oncol , vol.20 , pp. 289-296
    • Motzer, R.J.1    Bacik, J.2    Murphy, B.A.3    Russo, P.4    Mazumdar, M.5
  • 76
    • 79251574372 scopus 로고    scopus 로고
    • Prognostic factors for progression-free and overall survival with sunitinib targeted therapy and with cytokine as first-line therapy in patients with metastatic renal cell carcinoma
    • Patil S, Figlin RA, Hutson TE, et al,. Prognostic factors for progression-free and overall survival with sunitinib targeted therapy and with cytokine as first-line therapy in patients with metastatic renal cell carcinoma. Ann Oncol 2011; 22: 295-300
    • (2011) Ann Oncol , vol.22 , pp. 295-300
    • Patil, S.1    Figlin, R.A.2    Hutson, T.E.3
  • 77
    • 73349084973 scopus 로고    scopus 로고
    • Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: Results from a large, multicenter study
    • Heng DY, Xie W, Regan MM, et al,. Prognostic factors for overall survival in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted agents: results from a large, multicenter study. J Clin Oncol 2009; 27: 5794-9
    • (2009) J Clin Oncol , vol.27 , pp. 5794-5799
    • Heng, D.Y.1    Xie, W.2    Regan, M.M.3
  • 78
    • 57849117384 scopus 로고    scopus 로고
    • New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1)
    • Eisenhauer EA, Therasse P, Bogaerts J, et al,. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). Eur J Cancer 2009; 45: 228-47
    • (2009) Eur J Cancer , vol.45 , pp. 228-247
    • Eisenhauer, E.A.1    Therasse, P.2    Bogaerts, J.3
  • 79
    • 77953341948 scopus 로고    scopus 로고
    • Optimizing the size variation threshold for the CT evaluation of response in metastatic renal cell carcinoma treated with sunitinib
    • Thiam R, Fournier LS, Trinquart L, et al,. Optimizing the size variation threshold for the CT evaluation of response in metastatic renal cell carcinoma treated with sunitinib. Ann Oncol 2010; 21: 936-40
    • (2010) Ann Oncol , vol.21 , pp. 936-940
    • Thiam, R.1    Fournier, L.S.2    Trinquart, L.3
  • 80
    • 75749102468 scopus 로고    scopus 로고
    • CT response assessment combining reduction in both size and arterial phase density correlates with time to progression in metastatic renal cancer patients treated with targeted therapies
    • Nathan PD, Vinayan A, Stott D, Juttla J, Goh V,. CT response assessment combining reduction in both size and arterial phase density correlates with time to progression in metastatic renal cancer patients treated with targeted therapies. Cancer Biol Ther 2010; 9: 15-9
    • (2010) Cancer Biol Ther , vol.9 , pp. 15-19
    • Nathan, P.D.1    Vinayan, A.2    Stott, D.3    Juttla, J.4    Goh, V.5
  • 81
    • 77649272736 scopus 로고    scopus 로고
    • Choi response criteria for early prediction of clinical outcome in patients with metastatic renal cell cancer treated with sunitinib
    • van der Veldt AAM, Meijerink MR, van den Eertwegh AJ, Haanen JB, Boven E,. Choi response criteria for early prediction of clinical outcome in patients with metastatic renal cell cancer treated with sunitinib. Br J Cancer 2010; 102: 803-9
    • (2010) Br J Cancer , vol.102 , pp. 803-809
    • Van Der Veldt, A.A.M.1    Meijerink, M.R.2    Van Den Eertwegh, A.J.3    Haanen, J.B.4    Boven, E.5
  • 82
    • 75749157786 scopus 로고    scopus 로고
    • Measuring perfusion and permeability in renal cell carcinoma with dynamic contrast-enhanced MRI: A pilot study
    • Notohamiprodjo M, Sourbron S, Staehler M, et al,. Measuring perfusion and permeability in renal cell carcinoma with dynamic contrast-enhanced MRI: a pilot study. J Magn Reson Imaging 2010; 31: 490-501
    • (2010) J Magn Reson Imaging , vol.31 , pp. 490-501
    • Notohamiprodjo, M.1    Sourbron, S.2    Staehler, M.3
  • 83
    • 76749170854 scopus 로고    scopus 로고
    • Metastatic renal cell carcinoma treated with sunitinib: Early evaluation of treatment response using dynamic contrast-enhanced ultrasonography
    • Lassau N, Koscielny S, Albiges L, et al,. Metastatic renal cell carcinoma treated with sunitinib: early evaluation of treatment response using dynamic contrast-enhanced ultrasonography. Clin Cancer Res 2010; 16: 1216-25
    • (2010) Clin Cancer Res , vol.16 , pp. 1216-1225
    • Lassau, N.1    Koscielny, S.2    Albiges, L.3
  • 84
    • 65949095001 scopus 로고    scopus 로고
    • Magnetic resonance imaging as a biomarker in renal cell carcinoma
    • (Suppl.)
    • Pedrosa I, Alsop DC, Rofsky NM,. Magnetic resonance imaging as a biomarker in renal cell carcinoma. Cancer 2009; 115 (Suppl.): 2334-45
    • (2009) Cancer , vol.115 , pp. 2334-2345
    • Pedrosa, I.1    Alsop, D.C.2    Rofsky, N.M.3
  • 85
    • 77953757715 scopus 로고    scopus 로고
    • Plethora of agents, plethora of targets, plethora of side effects in metastatic renal cell carcinoma
    • Schmidinger M, Bellmunt J,. Plethora of agents, plethora of targets, plethora of side effects in metastatic renal cell carcinoma. Cancer Treat Rev 2010; 36: 416-24
    • (2010) Cancer Treat Rev , vol.36 , pp. 416-424
    • Schmidinger, M.1    Bellmunt, J.2
  • 86
    • 41149108218 scopus 로고    scopus 로고
    • Toxicities associated with the administration of sorafenib, sunitinib, and temsirolimus and their management in patients with metastatic renal cell carcinoma
    • Bhojani N, Jeldres C, Patard JJ, et al,. Toxicities associated with the administration of sorafenib, sunitinib, and temsirolimus and their management in patients with metastatic renal cell carcinoma. Eur Urol 2008; 53: 917-30
    • (2008) Eur Urol , vol.53 , pp. 917-930
    • Bhojani, N.1    Jeldres, C.2    Patard, J.J.3
  • 87
    • 66549084593 scopus 로고    scopus 로고
    • How to optimise treatment compliance in metastatic renal cell carcinoma with targeted agents
    • (Suppl.)
    • Ravaud A,. How to optimise treatment compliance in metastatic renal cell carcinoma with targeted agents. Ann Oncol 2009; 20 (Suppl. 1): i7-i12
    • (2009) Ann Oncol , vol.20 , Issue.1
    • Ravaud, A.1
  • 88
    • 77956621677 scopus 로고    scopus 로고
    • Optimising the use of sunitinib in metastatic renal cell carcinoma: An update from clinical practice
    • Schmidinger M, Arnold D, Szczylik C, Wagstaff J, Ravaud A,. Optimising the use of sunitinib in metastatic renal cell carcinoma: an update from clinical practice. Cancer Invest 2010; 28: 856-64
    • (2010) Cancer Invest , vol.28 , pp. 856-864
    • Schmidinger, M.1    Arnold, D.2    Szczylik, C.3    Wagstaff, J.4    Ravaud, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.