Treadmill rehabilitation treatment enhanced BDNF-TrkB but not NGF-TrkA signaling in a mouse intracerebral hemorrhage model

Neuroscience Letters

Volumn 529, Issue 1, 2012, Pages 28-32

  Chen, Jie ^a   Qin, Jie ^b   Su, Qian ^a   Liu, Zhixue ^a   Yang, Jian ^b  

^a INSTITUTE OF GEOLOGY AND GEOPHYSICS   (China)

^b Central Hospital of Xuhui District   (China)

Author keywords

BDNF; Brain repair; Intracerebral hemorrhage; P Y705 TrkB; Rehabilitation; Treadmill exercise

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; BROXURIDINE; NERVE GROWTH FACTOR; PROTEIN TYROSINE KINASE A;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN HEMORRHAGE; CELL LABELING; CONTROLLED STUDY; IMMUNOFLUORESCENCE; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TREADMILL EXERCISE;

ANIMALS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CEREBRAL HEMORRHAGE; EXERCISE THERAPY; MALE; MICE; MICE, INBRED C57BL; NERVE GROWTH FACTOR; NERVE REGENERATION; RECEPTOR, TRKB; SIGNAL TRANSDUCTION; STROKE; TREATMENT OUTCOME;

EID: 84867734391     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2012.09.021     Document Type: Article

References (25)

1. Ang E.T., Wong P.T., Moochhala S., Ng Y.K. Neuroprotection associated with running: is it a result of increased endogenous neurotrophic factors. Neuroscience 2003, 118:335-345.
2. Auriat A.M., Grams J.D., Yan R.H., Colbourne F. Forced exercise does not improve recovery after hemorrhagic stroke in rats. Brain Research 2006, 1109:183-191.
3. Bederson J.B., Pitts L.H., Tsuji M., Nishimura M.C., Davis R.L., Bartkowski H. Rat middle cerebral artery occlusion: evaluation of the model and development of a neurologic examination. Stroke 1986, 17:472-476.
4. Clark W., Gunion-Rinker L., Lessov N., Hazel K. Citicoline treatment for experimental intracerebral hemorrhage in mice. Stroke 1998, 29:2136-2140.
5. Ferrer I., Krupinski J., Goutan E., Marti E., Ambrosio S., Arenas E. Brain-derived neurotrophic factor reduces cortical cell death by ischemia after middle cerebral artery occlusion in the rat. Acta Neuropathologica 2001, 101:229-238.
6. Huang E.J., Reichardt L.F. Neurotrophins: roles in neuronal development and function. Annual Review of Neuroscience 2001, 24:677-736.
7. Jang S.W., Okada M., Sayeed I., Xiao G., Stein D., Jin P. Gambogic amide, a selective agonist for TrkA receptor that possesses robust neurotrophic activity, prevents neuronal cell death. Proceedings of the National Academy of Sciences of the United States of America 2007, 104:16329-16334.
8. Kaplan D.R., Miller F.D. Neurotrophin signal transduction in the nervous system. Current Opinion in Neurobiology 2000, 10:381-391.
9. Lee H.H., Shin M.S., Kim Y.S., Yang H.Y., Chang H.K., Lee T.H. Early treadmill exercise decreases intrastriatal hemorrhage-induced neuronal cell death and increases cell proliferation in the dentate gyrus of streptozotocin-induced hyperglycemic rats. Journal of Diabetes and Its Complications 2005, 19:339-346.
10. Longa E.Z., Weinstein P.R., Carlson S., Cummins R. Reversible middle cerebral artery occlusion without craniectomy in rats. Stroke 1989, 20:84-91.
11. Maclellan C.L., Grams J., Adams K., Colbourne F. Combined use of a cytoprotectant and rehabilitation therapy after severe intracerebral hemorrhage in rats. Brain Research 2005, 1063:40-47.
12. McAllister A.K., Katz L.C., Lo D.C. Neurotrophins and synaptic plasticity. Annual Review of Neuroscience 1999, 22:295-318.
13. Obermeier A., Bradshaw R.A., Seedorf K., Choidas A., Schlessinger J., Ullrich A. Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma. EMBO Journal 1994, 13:1585-1590.
14. Park J.W., Bang M.S., Kwon B.S., Park Y.K., Kim D.W., Shon S.M. Early treadmill training promotes motor function after hemorrhagic stroke in rats. Neuroscience Letters 2010, 471:104-108.
15. Patapoutian A., Reichardt L.F. Trk receptors: mediators of neurotrophin action. Current Opinion in Neurobiology 2001, 11:272-280.
16. Pierotti M.A., Greco A. Oncogenic rearrangements of the NTRK1/NGF receptor. Cancer Letters 2006, 232:90-98.
17. Ploughman M., Windle V., MacLellan C.L., White N., Dore J.J., Corbett D. Brain-derived neurotrophic factor contributes to recovery of skilled reaching after focal ischemia in rats. Stroke 2009, 40:1490-1495.
18. Qureshi A.I., Mendelow A.D., Hanley D.F. Intracerebral haemorrhage. Lancet 2009, 373:1632-1644.
19. Rosell A., Vilalta A., Garcia-Berrocoso T., Fernandez-Cadenas I., Domingues-Montanari S., Cuadrado E. Brain perihematoma genomic profile following spontaneous human intracerebral hemorrhage. PLoS ONE 2011, 6:e16750.
20. Segal R.A., Greenberg M.E. Intracellular signaling pathways activated by neurotrophic factors. Annual Review of Neuroscience 1996, 19:463-489.
21. Sgubin D., Aztiria E., Perin A., Longatti P., Leanza G. Activation of endogenous neural stem cells in the adult human brain following subarachnoid hemorrhage. Journal of Neuroscience Research 2007, 85:1647-1655.
22. Shen J., Xie L., Mao X., Zhou Y., Zhan R., Greenberg D.A. Neurogenesis after primary intracerebral hemorrhage in adult human brain. Journal of Cerebral Blood Flow and Metabolism 2008, 28:1460-1468.
23. Takamatsu Y., Ishida A., Hamakawa M., Tamakoshi K., Jung C.G., Ishida K. Treadmill running improves motor function and alters dendritic morphology in the striatum after collagenase-induced intracerebral hemorrhage in rats. Brain Research 2010, 1355:165-173.
24. Wojtowicz J.M., Kee N. BrdU assay for neurogenesis in rodents. Nature Protocols 2006, 1:1399-1405.
25. Yao R., Cooper G.M. Requirement for phosphatidylinositol-3 kinase in the prevention of apoptosis by nerve growth factor. Science 1995, 267:2003-2006.