메뉴 건너뛰기




Volumn 72, Issue 16, 2012, Pages 2129-2140

Pazopanib: In Advanced soft tissue sarcoma

Author keywords

Adis Drug Profiles; Pazopanib; Soft tissue sarcoma

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CLARITHROMYCIN; GADOLINIUM; KETOCONAZOLE; PAZOPANIB; PLACEBO; RIFAMPICIN; RITONAVIR; SORAFENIB; SUNITINIB;

EID: 84867712677     PISSN: 00126667     EISSN: 11791950     Source Type: Journal    
DOI: 10.2165/11209950-000000000-00000     Document Type: Article
Times cited : (24)

References (31)
  • 1
    • 79952116033 scopus 로고    scopus 로고
    • Diagnosis and management of soft tissue sarcoma
    • Dec 29
    • Sinha S, Peach AHS. Diagnosis and management of soft tissue sarcoma. BMJ 2010 Dec 29; 341: c7170
    • (2010) BMJ , vol.341
    • Sinha, S.1    Peach, A.H.S.2
  • 3
    • 23844442937 scopus 로고    scopus 로고
    • Soft-tissue sarcomas in adults
    • Aug 18
    • Clark MA, Fisher C, Judson I, et al. Soft-tissue sarcomas in adults. N Engl J Med 2005 Aug 18; 353 (7): 701-11
    • (2005) N Engl J Med , vol.353 , Issue.7 , pp. 701-711
    • Clark, M.A.1    Fisher, C.2    Judson, I.3
  • 4
    • 84862897753 scopus 로고    scopus 로고
    • Pazopanib in the treatment of soft tissue sarcoma
    • Jun
    • Schoffski P. Pazopanib in the treatment of soft tissue sarcoma. Expert Rev Anticancer Ther 2012 Jun; 12 (6): 711-23
    • (2012) Expert Rev Anticancer Ther , vol.12 , Issue.6 , pp. 711-723
    • Schoffski, P.1
  • 5
    • 77953502245 scopus 로고    scopus 로고
    • Guidelines for the management of soft tissue sarcomas
    • Grimer R, Judson I, Peake D, et al. Guidelines for the management of soft tissue sarcomas. Sarcoma 2010; 2010: 506182
    • (2010) Sarcoma , vol.2010 , pp. 506182
    • Grimer, R.1    Judson, I.2    Peake, D.3
  • 6
    • 77954337682 scopus 로고    scopus 로고
    • Soft tissue sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up [published erratum appears in Ann Oncol 2010 Aug; 21 (8): 1736]
    • May
    • Casali PG, Blay JY. Soft tissue sarcomas: ESMO clinical practice guidelines for diagnosis, treatment and follow-up [published erratum appears in Ann Oncol 2010 Aug; 21 (8): 1736]. Ann Oncol 2010 May; 21 Suppl. 5: 198-203
    • (2010) Ann Oncol , vol.21 , Issue.SUPPL. 5 , pp. 198-203
    • Casali, P.G.1    Blay, J.Y.2
  • 7
    • 34247516968 scopus 로고    scopus 로고
    • National Comprehensive Cancer Network Version 2.2012 [online] [Accessed 2012 Aug 1]
    • National Comprehensive Cancer Network-. NCCN clinical practice guidelines in oncology (NCCN Guidelines): soft tissue sarcoma, version 2.2012 [online]. Available from URL: http://www.nccn.org/professionals/physician-gls/f- guidelines.asp [Accessed 2012 Aug 1]
    • NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines): Soft Tissue Sarcoma
  • 8
    • 84862275926 scopus 로고    scopus 로고
    • The molecular biology of soft-tissue sarcomas and current trends in therapy
    • Quesada J, Amato R. The molecular biology of soft-tissue sarcomas and current trends in therapy. Sarcoma 2012; 2012: 849456
    • (2012) Sarcoma , vol.2012 , pp. 849456
    • Quesada, J.1    Amato, R.2
  • 9
    • 56749170762 scopus 로고    scopus 로고
    • Angiogenesis inhibition in non-GIST soft tissue sarcomas
    • Nov
    • Sleijfer S, Van Der Graaf WTA, Blay JY. Angiogenesis inhibition in non-GIST soft tissue sarcomas. Oncologist 2008 Nov; 13 (11): 1193-200
    • (2008) Oncologist , vol.13 , Issue.11 , pp. 1193-1200
    • Sleijfer, S.1    Van Der Graaf Wta2    Blay, J.Y.3
  • 10
    • 84875379169 scopus 로고    scopus 로고
    • US Food and Drug Administration [online] [Accessed 2012 Oct 8]
    • US Food and Drug Administration. Votrient (pazopanib) tablets: US prescribing information [online]. Available from URL: http://www.accessdata.fda. gov/drugsatfda-docs/label/2012/022465s-010S-012lbl.pdf [Accessed 2012 Oct 8]
    • Votrient (Pazopanib) Tablets: US Prescribing Information
  • 11
    • 84857253222 scopus 로고    scopus 로고
    • European Medicines Agency [online] [Accessed 2012 Oct 8]
    • European Medicines Agency. Votrient film-coated tablets: summary of product characteristics [online]. Available from URL: http://www.ema.europa.eu/ docs/en-GB/document-library/EPAR-Product-Information/human/001141/WC 500094272.pdf [Accessed 2012 Oct 8]
    • Votrient Film-coated Tablets: Summary of Product Characteristics
  • 13
    • 34447322566 scopus 로고    scopus 로고
    • Pharmacokineticpharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity
    • Jul 1
    • Kumar R, Knick VB, Rudolph SK, et al. Pharmacokineticpharmacodynamic correlation from mouse to human with pazopanib, a multikinase angiogenesis inhibitor with potent antitumor and antiangiogenic activity. Mol Cancer Ther 2007 Jul 1; 6 (7): 2012-21
    • (2007) Mol Cancer Ther , vol.6 , Issue.7 , pp. 2012-2021
    • Kumar, R.1    Knick, V.B.2    Rudolph, S.K.3
  • 14
    • 33845882259 scopus 로고    scopus 로고
    • The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma
    • Dec 19
    • Podar K, Tonon G, Sattler M, et al. The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma. PNAS 2006 Dec 19; 103 (51): 19478-83
    • (2006) PNAS , vol.103 , Issue.51 , pp. 19478-19483
    • Podar, K.1    Tonon, G.2    Sattler, M.3
  • 15
    • 49449117755 scopus 로고    scopus 로고
    • Discovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2- pyrimidinyl] amino]-2-methyl-benzenesulfonamide (pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor
    • Aug
    • Harris PA, Boloor A, Cheung M, et al. Discovery of 5-[[4-[(2,3-dimethyl- 2H-indazol-6-yl)methylamino]-2-pyrimidinyl] amino]-2-methyl-benzenesulfonamide (pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor. J Med Chem 2008 Aug; 51 (15): 4632-40
    • (2008) J Med Chem , vol.51 , Issue.15 , pp. 4632-4640
    • Harris, P.A.1    Boloor, A.2    Cheung, M.3
  • 16
    • 70449523183 scopus 로고    scopus 로고
    • Myelosuppression and kinase selectivity of multikinase angiogenesis inhibitors
    • Nov 17
    • Kumar R, Crouthamel MC, Rominger DH, et al. Myelosuppression and kinase selectivity of multikinase angiogenesis inhibitors. Br J Cancer 2009 Nov 17; 101 (10): 1717-23
    • (2009) Br J Cancer , vol.101 , Issue.10 , pp. 1717-1723
    • Kumar, R.1    Crouthamel, M.C.2    Rominger, D.H.3
  • 17
    • 77953419154 scopus 로고    scopus 로고
    • Effect of pazopanib on tumor microenvironment and liposome delivery
    • Jun
    • Tailor TD, Hanna G, Yarmolenko PS, et al. Effect of pazopanib on tumor microenvironment and liposome delivery. Mol Cancer Ther 2010 Jun; 9 (6): 1798-808
    • (2010) Mol Cancer Ther , vol.9 , Issue.6 , pp. 1798-1808
    • Tailor, T.D.1    Hanna, G.2    Yarmolenko, P.S.3
  • 18
    • 67449164582 scopus 로고    scopus 로고
    • Phase i trial of pazopanib in patients with advanced cancer
    • Jun 15
    • Hurwitz HI, Dowlati A, Saini S, et al. Phase I trial of pazopanib in patients with advanced cancer. Clin Cancer Res 2009 Jun 15; 15 (12): 4220-7
    • (2009) Clin Cancer Res , vol.15 , Issue.12 , pp. 4220-4227
    • Hurwitz, H.I.1    Dowlati, A.2    Saini, S.3
  • 20
    • 78449297407 scopus 로고    scopus 로고
    • A phase i study of the pharmacokinetic and safety profiles of oral pazopanib with a high-fat or low-fat meal in patients with advanced solid tumors
    • Dec
    • Heath EI, Chiorean EG, Sweeney CJ, et al. A phase I study of the pharmacokinetic and safety profiles of oral pazopanib with a high-fat or low-fat meal in patients with advanced solid tumors. Clin Pharmacol Ther 2010 Dec; 88 (6): 818-23
    • (2010) Clin Pharmacol Ther , vol.88 , Issue.6 , pp. 818-823
    • Heath, E.I.1    Chiorean, E.G.2    Sweeney, C.J.3
  • 21
    • 84866728199 scopus 로고    scopus 로고
    • A phase i pharmacokinetic and safety evaluation of oral pazopanib dosing administered as crushed tablet or oral suspension in patients with advanced solid tumors
    • Aug
    • Heath EI, Forman K, Malburg L, et al. A phase I pharmacokinetic and safety evaluation of oral pazopanib dosing administered as crushed tablet or oral suspension in patients with advanced solid tumors. Invest New Drugs 2012 Aug; 30 (4): 1566-74
    • (2012) Invest New Drugs , vol.30 , Issue.4 , pp. 1566-1574
    • Heath, E.I.1    Forman, K.2    Malburg, L.3
  • 22
    • 84861098484 scopus 로고    scopus 로고
    • Pazopanib for metastatic soft-tissue sarcoma (PALETTE): A randomised, double-blind, placebo-controlled phase 3 trial
    • May 19
    • van der Graaf WTA, Blay JY, Chawla SP, et al. Pazopanib for metastatic soft-tissue sarcoma (PALETTE): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet 2012 May 19; 379 (9829): 1879-86
    • (2012) Lancet , vol.379 , Issue.9829 , pp. 1879-1886
    • Van Der Graaf Wta1    Blay, J.Y.2    Chawla, S.P.3
  • 23
    • 67650337802 scopus 로고    scopus 로고
    • Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: A phase II study from the European Organisation for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC Study 62043)
    • Jul 1
    • Sleijfer S, Ray-Coquard I, Papai Z, et al. Pazopanib, a multikinase angiogenesis inhibitor, in patients with relapsed or refractory advanced soft tissue sarcoma: a phase II study from the European Organisation for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group (EORTC Study 62043). J Clin Oncol 2009 Jul 1; 27 (19): 3126-32
    • (2009) J Clin Oncol , vol.27 , Issue.19 , pp. 3126-3132
    • Sleijfer, S.1    Ray-Coquard, I.2    Papai, Z.3
  • 24
    • 84891737076 scopus 로고    scopus 로고
    • Soluble factors (SF) associated with efficacy and toxicity of pazopanib (PZB) in advanced soft tissue sarcoma (STS) patients (pts): An EORTC-STBSG study [abstract]
    • May 20
    • Sleijfer S, Van Glabbeke MM, Lamers C, et al. Soluble factors (SF) associated with efficacy and toxicity of pazopanib (PZB) in advanced soft tissue sarcoma (STS) patients (pts): an EORTC-STBSG study [abstract]. J Clin Oncol 2010 May 20; 28 (15 Suppl. 1)
    • (2010) J Clin Oncol , vol.28 , Issue.15 SUPPL. 1
    • Sleijfer, S.1    Van Glabbeke, M.M.2    Lamers, C.3
  • 25
    • 85081770878 scopus 로고    scopus 로고
    • PALETTE: Final overall survival (OS) data and predictive factors for OS of EORTC 62072/GSK VEG110727, a randomized double-blind phase III trial of pazopanib versus placebo in advanced soft tissue sarcoma (STS) patients [abstract no. 10009]
    • Van Der Graaf WTA, Blay JY, Chawla SP, et al. PALETTE: final overall survival (OS) data and predictive factors for OS of EORTC 62072/GSK VEG110727, a randomized double-blind phase III trial of pazopanib versus placebo in advanced soft tissue sarcoma (STS) patients [abstract no. 10009]. J Clin Oncol 2012; 30 Suppl.
    • (2012) J Clin Oncol , vol.30 , Issue.SUPPL.
    • Van Der Graaf Wta1    Blay, J.Y.2    Chawla, S.P.3
  • 26
    • 85081764296 scopus 로고    scopus 로고
    • Final results of health-related quality of life (HRQOL) Results from PALETTE: A randomized double-blind phase III trial of pazopanib versus placebo in patients with soft tissue sarcoma (STS) whose disease has progressed during or following prior chemotherapy. An EORTC STBSG Global Network Study (EORTC 62072) [poster No. 1493P]
    • Sep 28-Oct 2; Vienna
    • Coens C, van der Graaf WTA, Blay JY, et al. Final results of health-related quality of life (HRQOL) results from PALETTE: a randomized double-blind phase III trial of pazopanib versus placebo in patients with soft tissue sarcoma (STS) whose disease has progressed during or following prior chemotherapy. An EORTC STBSG global network study (EORTC 62072) [poster no. 1493P]. European Organisation for Research and Treatment of Cancer; 2012 Sep 28-Oct 2; Vienna
    • (2012) European Organisation for Research and Treatment of Cancer
    • Coens, C.1    Van Der Graaf Wta2    Blay, J.Y.3
  • 29
    • 85081763181 scopus 로고    scopus 로고
    • GlaxoSmithKline London: GlaxoSmithKline (Data on file)
    • GlaxoSmithKline. PALETTE: academic vs regulatory analysis. London: GlaxoSmithKline, 2011. (Data on file)
    • (2011) PALETTE: Academic Vs Regulatory Analysis
  • 30
    • 51049106109 scopus 로고    scopus 로고
    • Anthracycline-induced cardotoxicity and the cardiac-sparing effect of liposomal formulation
    • Rahman AM, Yusuf SW, Ewer MS. Anthracycline-induced cardotoxicity and the cardiac-sparing effect of liposomal formulation. Int J Nanomedicine 2007; 2 (4): 567-83
    • (2007) Int J Nanomedicine , vol.2 , Issue.4 , pp. 567-583
    • Rahman, A.M.1    Yusuf, S.W.2    Ewer, M.S.3
  • 31
    • 77951666852 scopus 로고    scopus 로고
    • Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism
    • Apr 27
    • Xu CF, Reck BH, Xue Z, et al. Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism. Br J Cancer 2010 Apr 27; 102 (9): 1371-7
    • (2010) Br J Cancer , vol.102 , Issue.9 , pp. 1371-1377
    • Xu, C.F.1    Reck, B.H.2    Xue, Z.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.