메뉴 건너뛰기




Volumn 60, Issue 9, 2012, Pages 658-674

A Multifunctional Mesothelin Antibody-tagged Microparticle Targets Human Mesotheliomas

Author keywords

amorphous silica; malignant mesothelioma; mesothelin; targeted microparticle

Indexed keywords

ACID PREPARED MESOPOROUS SPHERE; BOVINE SERUM ALBUMIN; MESOTHELIN; MICROSPHERE; UNCLASSIFIED DRUG; DIFFERENTIATION ANTIGEN; DRUG CARRIER; FLUORESCENT DYE; GADOLINIUM; GLYCOSYLPHOSPHATIDYLINOSITOL ANCHORED PROTEIN; MONOCLONAL ANTIBODY; SILICON DIOXIDE;

EID: 84867681494     PISSN: 00221554     EISSN: None     Source Type: Journal    
DOI: 10.1369/0022155412452567     Document Type: Article
Times cited : (5)

References (70)
  • 1
    • 0030999558 scopus 로고    scopus 로고
    • Gene therapy for lung cancer and mesothelioma
    • Albelda SM.Gene therapy for lung cancer and mesothelioma.Chest. 1997;111:144S-149S.
    • (1997) Chest , vol.111
    • Albelda, S.M.1
  • 5
    • 6344229772 scopus 로고    scopus 로고
    • Toxicological hazards of inhaled nanoparticles-potential implications for drug delivery
    • Borm PJ,Kreyling W.Toxicological hazards of inhaled nanoparticles-potential implications for drug delivery.J Nanosci Nanotechnol. 2004;4:521-531.
    • (2004) J Nanosci Nanotechnol , vol.4 , pp. 521-531
    • Borm, P.J.1    Kreyling, W.2
  • 7
    • 0030069718 scopus 로고    scopus 로고
    • Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers
    • Chang K,Pastan I.Molecular cloning of mesothelin, a differentiation antigen present on mesothelium, mesotheliomas, and ovarian cancers.Proc Natl Acad Sci U S A. 1996;93:136-140.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 136-140
    • Chang, K.1    Pastan, I.2
  • 8
    • 78649940152 scopus 로고    scopus 로고
    • Enhanced uptake of porous silica microparticles by bifunctional surface modification with a targeting antibody and a biocompatible polymer
    • Cheng K,Blumen SR,MacPherson MB,Steinbacher JL,Mossman BT,Landry CC.Enhanced uptake of porous silica microparticles by bifunctional surface modification with a targeting antibody and a biocompatible polymer.ACS Appl Mater Interfaces. 2010;2:2489-2495.
    • (2010) ACS Appl Mater Interfaces , vol.2 , pp. 2489-2495
    • Cheng, K.1    Blumen, S.R.2    MacPherson, M.B.3    Steinbacher, J.L.4    Mossman, B.T.5    Landry, C.C.6
  • 9
    • 84856291187 scopus 로고    scopus 로고
    • Binding of HIV-1 gp120 glycoprotein to silica nanoparticles modified with CD4 glycoprotein and CD4 peptide fragments
    • Cheng K,El-Boubbou K,Landry CC.Binding of HIV-1 gp120 glycoprotein to silica nanoparticles modified with CD4 glycoprotein and CD4 peptide fragments.ACS Appl Mater Interfaces. 2012;4:235-243.
    • (2012) ACS Appl Mater Interfaces , vol.4 , pp. 235-243
    • Cheng, K.1    El-Boubbou, K.2    Landry, C.C.3
  • 10
    • 0033979731 scopus 로고    scopus 로고
    • Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics
    • Dickson MA,Hahn WC,Ino Y,Ronfard V,Wu JY,Weinberg RA,Louis DN,Li FP,Rheinwald JG.Human keratinocytes that express hTERT and also bypass a p16(INK4a)-enforced mechanism that limits life span become immortal yet retain normal growth and differentiation characteristics.Mol Cell Biol. 2000;20:1436-1447.
    • (2000) Mol Cell Biol , vol.20 , pp. 1436-1447
    • Dickson, M.A.1    Hahn, W.C.2    Ino, Y.3    Ronfard, V.4    Wu, J.Y.5    Weinberg, R.A.6    Louis, D.N.7    Li, F.P.8    Rheinwald, J.G.9
  • 11
    • 2542443539 scopus 로고    scopus 로고
    • Defective core-apoptosis signalling in diffuse malignant pleural mesothelioma: opportunities for effective drug development
    • Fennell DA,Rudd RM.Defective core-apoptosis signalling in diffuse malignant pleural mesothelioma: opportunities for effective drug development.Lancet Oncol. 2004;5:354-362.
    • (2004) Lancet Oncol , vol.5 , pp. 354-362
    • Fennell, D.A.1    Rudd, R.M.2
  • 13
    • 0029011711 scopus 로고
    • Endocytosis and transcytosis of albumin gold through mice peritoneal mesothelium
    • Gotloib L,Shostak A.Endocytosis and transcytosis of albumin gold through mice peritoneal mesothelium.Kidney Int. 1995;47:1274-1284.
    • (1995) Kidney Int , vol.47 , pp. 1274-1284
    • Gotloib, L.1    Shostak, A.2
  • 14
    • 84858410873 scopus 로고    scopus 로고
    • Systemic treatment of malignant pleural mesothelioma
    • Grosso F,Scagliotti GV.Systemic treatment of malignant pleural mesothelioma.Future Oncol. 2012;8:293-305.
    • (2012) Future Oncol , vol.8 , pp. 293-305
    • Grosso, F.1    Scagliotti, G.V.2
  • 16
    • 44449147673 scopus 로고    scopus 로고
    • Manufactured nanoparticles: their uptake and effects on fish-a mechanistic analysis
    • Handy RD,Henry TB,Scown TM,Johnston BD,Tyler CR.Manufactured nanoparticles: their uptake and effects on fish-a mechanistic analysis.Ecotoxicology. 2008;17:396-409.
    • (2008) Ecotoxicology , vol.17 , pp. 396-409
    • Handy, R.D.1    Henry, T.B.2    Scown, T.M.3    Johnston, B.D.4    Tyler, C.R.5
  • 17
    • 3042621639 scopus 로고    scopus 로고
    • Mesothelin: a new target for immunotherapy
    • Hassan R,Bera T,Pastan I.Mesothelin: a new target for immunotherapy.Clin Cancer Res. 2004;10:3937-3942.
    • (2004) Clin Cancer Res , vol.10 , pp. 3937-3942
    • Hassan, R.1    Bera, T.2    Pastan, I.3
  • 18
    • 37249025607 scopus 로고    scopus 로고
    • Anti-mesothelin immunotoxin SS1P in combination with gemcitabine results in increased activity against mesothelin-expressing tumor xenografts
    • Hassan R,Broaddus VC,Wilson S,Liewehr DJ,Zhang J.Anti-mesothelin immunotoxin SS1P in combination with gemcitabine results in increased activity against mesothelin-expressing tumor xenografts.Clin Cancer Res. 2007;13:7166-7171.
    • (2007) Clin Cancer Res , vol.13 , pp. 7166-7171
    • Hassan, R.1    Broaddus, V.C.2    Wilson, S.3    Liewehr, D.J.4    Zhang, J.5
  • 19
    • 34548858453 scopus 로고    scopus 로고
    • Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers
    • Hassan R,Bullock S,Premkumar A,Kreitman RJ,Kindler H,Willingham MC,Pastan I.Phase I study of SS1P, a recombinant anti-mesothelin immunotoxin given as a bolus I.V. infusion to patients with mesothelin-expressing mesothelioma, ovarian, and pancreatic cancers.Clin Cancer Res. 2007;13:5144-5149.
    • (2007) Clin Cancer Res , vol.13 , pp. 5144-5149
    • Hassan, R.1    Bullock, S.2    Premkumar, A.3    Kreitman, R.J.4    Kindler, H.5    Willingham, M.C.6    Pastan, I.7
  • 20
  • 22
    • 37249038187 scopus 로고    scopus 로고
    • Mesothelin targeted cancer immunotherapy
    • Hassan R,Ho M.Mesothelin targeted cancer immunotherapy.Eur J Cancer. 2008;44:46-53.
    • (2008) Eur J Cancer , vol.44 , pp. 46-53
    • Hassan, R.1    Ho, M.2
  • 23
    • 33750713646 scopus 로고    scopus 로고
    • Mesothelioma environment comprises cytokines and T-regulatory cells that suppress immune responses
    • Hegmans JP,Hemmes A,Hammad H,Boon L,Hoogsteden HC,Lambrecht BN.Mesothelioma environment comprises cytokines and T-regulatory cells that suppress immune responses.Eur Respir J. 2006;27:1086-1095.
    • (2006) Eur Respir J , vol.27 , pp. 1086-1095
    • Hegmans, J.P.1    Hemmes, A.2    Hammad, H.3    Boon, L.4    Hoogsteden, H.C.5    Lambrecht, B.N.6
  • 29
    • 18844419982 scopus 로고    scopus 로고
    • Humoral immune response to mesothelin in mesothelioma and ovarian cancer patients
    • Ho M,Hassan R,Zhang J,Wang QC,Onda M,Bera T,Pastan I.Humoral immune response to mesothelin in mesothelioma and ovarian cancer patients.Clin Cancer Res. 2005;11:3814-3820.
    • (2005) Clin Cancer Res , vol.11 , pp. 3814-3820
    • Ho, M.1    Hassan, R.2    Zhang, J.3    Wang, Q.C.4    Onda, M.5    Bera, T.6    Pastan, I.7
  • 34
    • 69349100450 scopus 로고    scopus 로고
    • Phase I trial of continuous infusion anti-mesothelin recombinant immunotoxin SS1P
    • Kreitman RJ,Hassan R,Fitzgerald DJ,Pastan I.Phase I trial of continuous infusion anti-mesothelin recombinant immunotoxin SS1P.Clin Cancer Res. 2009;15:5274-5279.
    • (2009) Clin Cancer Res , vol.15 , pp. 5274-5279
    • Kreitman, R.J.1    Hassan, R.2    Fitzgerald, D.J.3    Pastan, I.4
  • 35
    • 84856519280 scopus 로고    scopus 로고
    • A live-attenuated listeria vaccine (ANZ-100) and a live-attenuated listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: phase I studies of safety and immune induction
    • Le DT,Brockstedt DG,Nir-Paz R,Hampl J,Mathur S,Nemunaitis J,Sterman DH,Hassan R,Lutz E,Moyer B, et al.A live-attenuated listeria vaccine (ANZ-100) and a live-attenuated listeria vaccine expressing mesothelin (CRS-207) for advanced cancers: phase I studies of safety and immune induction.Clin Cancer Res. 2012;18:858-868.
    • (2012) Clin Cancer Res , vol.18 , pp. 858-868
    • Le, D.T.1    Brockstedt, D.G.2    Nir-Paz, R.3    Hampl, J.4    Mathur, S.5    Nemunaitis, J.6    Sterman, D.H.7    Hassan, R.8    Lutz, E.9    Moyer, B.10
  • 36
    • 76249096802 scopus 로고    scopus 로고
    • CD44-targeted microparticles for delivery of cisplatin to peritoneal metastases
    • Li SD,Howell SB.CD44-targeted microparticles for delivery of cisplatin to peritoneal metastases.Mol Pharm. 2009;7:280-290.
    • (2009) Mol Pharm , vol.7 , pp. 280-290
    • Li, S.D.1    Howell, S.B.2
  • 37
    • 3142644996 scopus 로고    scopus 로고
    • Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression
    • Mantovani A,Allavena P,Sica A.Tumour-associated macrophages as a prototypic type II polarised phagocyte population: role in tumour progression.Eur J Cancer. 2004;40:1660-1667.
    • (2004) Eur J Cancer , vol.40 , pp. 1660-1667
    • Mantovani, A.1    Allavena, P.2    Sica, A.3
  • 39
    • 17044426222 scopus 로고    scopus 로고
    • Acute toxicity of intravenously administered microfabricated silicon dioxide drug delivery particles in mice: preliminary findings
    • Martin FJ,Melnik K,West T,Shapiro J,Cohen M,Boiarski AA,Ferrari M.Acute toxicity of intravenously administered microfabricated silicon dioxide drug delivery particles in mice: preliminary findings.Drugs R D. 2005;6:71-81.
    • (2005) Drugs R D , vol.6 , pp. 71-81
    • Martin, F.J.1    Melnik, K.2    West, T.3    Shapiro, J.4    Cohen, M.5    Boiarski, A.A.6    Ferrari, M.7
  • 40
    • 0037310823 scopus 로고    scopus 로고
    • Expression of calretinin, thrombomodulin, keratin 5, and mesothelin in lung carcinomas of different types: an immunohistochemical analysis of 596 tumors in comparison with epithelioid mesotheliomas of the pleura
    • Miettinen M,Sarlomo-Rikala M.Expression of calretinin, thrombomodulin, keratin 5, and mesothelin in lung carcinomas of different types: an immunohistochemical analysis of 596 tumors in comparison with epithelioid mesotheliomas of the pleura.Am J Surg Pathol. 2003;27:150-158.
    • (2003) Am J Surg Pathol , vol.27 , pp. 150-158
    • Miettinen, M.1    Sarlomo-Rikala, M.2
  • 41
    • 0034605039 scopus 로고    scopus 로고
    • Endothelial cell-surface gp60 activates vesicle formation and trafficking via Gi-coupled Src kinase signaling pathway
    • Minshall RD,Tiruppathi C,Vogel SM,Niles WD,Gilchrist A,Hamm HE,Malik AB.Endothelial cell-surface gp60 activates vesicle formation and trafficking via Gi-coupled Src kinase signaling pathway.J Cell Biol. 2000;150:1057-1070.
    • (2000) J Cell Biol , vol.150 , pp. 1057-1070
    • Minshall, R.D.1    Tiruppathi, C.2    Vogel, S.M.3    Niles, W.D.4    Gilchrist, A.5    Hamm, H.E.6    Malik, A.B.7
  • 43
    • 42249115328 scopus 로고    scopus 로고
    • Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma
    • Miselis NR,Wu ZJ,Van Rooijen N,Kane AB.Targeting tumor-associated macrophages in an orthotopic murine model of diffuse malignant mesothelioma.Mol Cancer Ther. 2008;7:788-799.
    • (2008) Mol Cancer Ther , vol.7 , pp. 788-799
    • Miselis, N.R.1    Wu, Z.J.2    van Rooijen, N.3    Kane, A.B.4
  • 44
    • 0025156969 scopus 로고
    • Asbestos: scientific developments and implications for public policy
    • Mossman BT,Bignon J,Corn M,Seaton A,Gee JB.Asbestos: scientific developments and implications for public policy.Science. 1990;247:294-301.
    • (1990) Science , vol.247 , pp. 294-301
    • Mossman, B.T.1    Bignon, J.2    Corn, M.3    Seaton, A.4    Gee, J.B.5
  • 45
    • 0037064211 scopus 로고    scopus 로고
    • Size-exclusion chromatography of low-molecular-mass polymers using mesoporous silica
    • Nassivera T,Eklund AG,Landry CC.Size-exclusion chromatography of low-molecular-mass polymers using mesoporous silica.J Chromatogr A. 2002;973:97-101.
    • (2002) J Chromatogr A , vol.973 , pp. 97-101
    • Nassivera, T.1    Eklund, A.G.2    Landry, C.C.3
  • 47
    • 20644449754 scopus 로고    scopus 로고
    • Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles
    • Oberdorster G,Oberdorster E,Oberdorster J.Nanotoxicology: an emerging discipline evolving from studies of ultrafine particles.Environ Health Perspect. 2005;113:823-839.
    • (2005) Environ Health Perspect , vol.113 , pp. 823-839
    • Oberdorster, G.1    Oberdorster, E.2    Oberdorster, J.3
  • 48
    • 1642540193 scopus 로고    scopus 로고
    • Translocation of bioactive peptides across cell membranes by carbon nanotubes
    • Pantarotto D,Briand JP,Prato M,Bianco A.Translocation of bioactive peptides across cell membranes by carbon nanotubes.Chem Commun (Camb). 2004;2004:16-17.
    • (2004) Chem Commun (Camb) , vol.2004 , pp. 16-17
    • Pantarotto, D.1    Briand, J.P.2    Prato, M.3    Bianco, A.4
  • 50
    • 84863806057 scopus 로고    scopus 로고
    • Modulating mesothelin shedding to improve therapy
    • Pastan I,Zhang Y.Modulating mesothelin shedding to improve therapy.Oncotarget. 2012;3:114-115.
    • (2012) Oncotarget , vol.3 , pp. 114-115
    • Pastan, I.1    Zhang, Y.2
  • 51
    • 0023184362 scopus 로고
    • Characterization of a human malignant mesothelioma cell line (H-MESO-1): a biphasic solid and ascitic tumor model
    • Reale FR,Griffin TW,Compton JM,Graham S,Townes PL,Bogden A.Characterization of a human malignant mesothelioma cell line (H-MESO-1): a biphasic solid and ascitic tumor model.Cancer Res. 1987;47:3199-3205.
    • (1987) Cancer Res , vol.47 , pp. 3199-3205
    • Reale, F.R.1    Griffin, T.W.2    Compton, J.M.3    Graham, S.4    Townes, P.L.5    Bogden, A.6
  • 58
    • 0033613088 scopus 로고    scopus 로고
    • Soluble member(s) of the mesothelin/megakaryocyte potentiating factor family are detectable in sera from patients with ovarian carcinoma
    • Scholler N,Fu N,Yang Y,Ye Z,Goodman GE,Hellstrom KE,Hellstrom I.Soluble member(s) of the mesothelin/megakaryocyte potentiating factor family are detectable in sera from patients with ovarian carcinoma.Proc Natl Acad Sci U S A. 1999;96:11531-11536.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 11531-11536
    • Scholler, N.1    Fu, N.2    Yang, Y.3    Ye, Z.4    Goodman, G.E.5    Hellstrom, K.E.6    Hellstrom, I.7
  • 61
    • 33745990808 scopus 로고    scopus 로고
    • Comprehensive management of diffuse malignant peritoneal mesothelioma
    • Sugarbaker P,Yan T,Stuart O,Yoo D.Comprehensive management of diffuse malignant peritoneal mesothelioma.Eur J Surg Oncol. 2006;32:686-691.
    • (2006) Eur J Surg Oncol , vol.32 , pp. 686-691
    • Sugarbaker, P.1    Yan, T.2    Stuart, O.3    Yoo, D.4
  • 63
    • 67651161975 scopus 로고    scopus 로고
    • Pharmacokinetics and pharmacodynamics of perioperative cancer chemotherapy in peritoneal surface malignancy
    • Van der Speeten K,Stuart OA,Sugarbaker PH.Pharmacokinetics and pharmacodynamics of perioperative cancer chemotherapy in peritoneal surface malignancy.Cancer J. 2009;15:216-224.
    • (2009) Cancer J , vol.15 , pp. 216-224
    • van der Speeten, K.1    Stuart, O.A.2    Sugarbaker, P.H.3
  • 64
    • 0038283091 scopus 로고    scopus 로고
    • Cytoreductive surgery combined with intraoperative hyperthermic intrathoracic chemotherapy for stage I malignant pleural mesothelioma
    • van Ruth S,Baas P,Haas RL,Rutgers EJ,Verwaal VJ,Zoetmulder FA.Cytoreductive surgery combined with intraoperative hyperthermic intrathoracic chemotherapy for stage I malignant pleural mesothelioma.Ann Surg Oncol. 2003;10:176-182.
    • (2003) Ann Surg Oncol , vol.10 , pp. 176-182
    • van Ruth, S.1    Baas, P.2    Haas, R.L.3    Rutgers, E.J.4    Verwaal, V.J.5    Zoetmulder, F.A.6
  • 65
    • 0037265430 scopus 로고    scopus 로고
    • Pharmacokinetics of doxorubicin and cisplatin used in intraoperative hyperthermic intrathoracic chemotherapy after cytoreductive surgery for malignant pleural mesothelioma and pleural thymoma
    • van Ruth S,van Tellingen O,Korse CM,Verwaal VJ,Zoetmulder FA.Pharmacokinetics of doxorubicin and cisplatin used in intraoperative hyperthermic intrathoracic chemotherapy after cytoreductive surgery for malignant pleural mesothelioma and pleural thymoma.Anticancer Drugs. 2003;14:57-65.
    • (2003) Anticancer Drugs , vol.14 , pp. 57-65
    • van Ruth, S.1    van Tellingen, O.2    Korse, C.M.3    Verwaal, V.J.4    Zoetmulder, F.A.5
  • 67
    • 0034835816 scopus 로고    scopus 로고
    • Inhaled amorphous silica particulates: what do we know about their toxicological profiles?
    • Warheit DB.Inhaled amorphous silica particulates: what do we know about their toxicological profiles?.J Environ Pathol Toxicol Oncol. 2001;20:133-141.
    • (2001) J Environ Pathol Toxicol Oncol , vol.20 , pp. 133-141
    • Warheit, D.B.1
  • 68
    • 33748310797 scopus 로고    scopus 로고
    • Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm
    • Xia T,Kovochich M,Brant J,Hotze M,Sempf J,Oberley T,Sioutas C,Yeh JI,Wiesner MR,Nel AE.Comparison of the abilities of ambient and manufactured nanoparticles to induce cellular toxicity according to an oxidative stress paradigm.Nano Lett. 2006;6:1794-1807.
    • (2006) Nano Lett , vol.6 , pp. 1794-1807
    • Xia, T.1    Kovochich, M.2    Brant, J.3    Hotze, M.4    Sempf, J.5    Oberley, T.6    Sioutas, C.7    Yeh, J.I.8    Wiesner, M.R.9    Nel, A.E.10
  • 69
    • 79958030031 scopus 로고    scopus 로고
    • The evolution of multimodality therapy for malignant pleural mesothelioma
    • Zauderer MG,Krug LM.The evolution of multimodality therapy for malignant pleural mesothelioma.Curr Treat Options Oncol. 2011;12:163-172.
    • (2011) Curr Treat Options Oncol , vol.12 , pp. 163-172
    • Zauderer, M.G.1    Krug, L.M.2
  • 70
    • 80052190561 scopus 로고    scopus 로고
    • Cytotoxic activity of immunotoxin SS1P is modulated by TACE-dependent mesothelin shedding
    • Zhang Y,Chertov O,Zhang J,Hassan R,Pastan I.Cytotoxic activity of immunotoxin SS1P is modulated by TACE-dependent mesothelin shedding.Cancer Res. 2011;71:5915-5922.
    • (2011) Cancer Res , vol.71 , pp. 5915-5922
    • Zhang, Y.1    Chertov, O.2    Zhang, J.3    Hassan, R.4    Pastan, I.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.