The relationship between regional and inter-regional functional connectivity deficits in schizophrenia

Human Brain Mapping

Volumn 33, Issue 11, 2012, Pages 2535-2549

  Zalesky, Andrew ^a   Fornito, Alex ^a,b   Egan, Gary F ^a   Pantelis, Christos ^a   Bullmore, Edward T ^b  

^a UNIVERSITY OF MELBOURNE   (Australia)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Functioncal connectivity mapping; Network mapping; Schizophrenia

Indexed keywords

ADULT; ARTICLE; BRAIN; BRAIN MAPPING; BRAIN REGION; CLINICAL ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; FEMALE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GRAY MATTER; HUMAN; INTER REGIONAL FUNCTIONAL CONNECTIVITY DEFICIT; MALE; NERVE CELL NETWORK; NERVE TRACT; NEUROLOGIC DISEASE; PRIORITY JOURNAL; REGIONAL FUNCTIONAL CONNECTIVITY DEFICIT; SCHIZOPHRENIA; WHOLE BRAIN FUNCTIONAL CONNECTIVITY MAPPING;

ADULT; BRAIN; BRAIN MAPPING; FEMALE; HUMANS; IMAGE INTERPRETATION, COMPUTER-ASSISTED; MAGNETIC RESONANCE IMAGING; MALE; NEURAL PATHWAYS; SCHIZOPHRENIA;

EID: 84867628690     PISSN: 10659471     EISSN: 10970193     Source Type: Journal    
DOI: 10.1002/hbm.21379     Document Type: Article

References (68)

1. Agartz I, Andersson JLR, Skare S (2001): Abnormal brain white matter in schizophrenia: A diffusion tensor imaging study. Neuroreport 12: 2251-2254.
2. Alexander-Bloch AF, Gogtay N, Meunier D, Birn R, Clasen L, Lalonde F, Lenroot R, Giedd J, Bullmore ET (2010): Disrupted modularity and local connectivity of brain functional networks in childhood-onset schizophrenia. Front Syst Neurosci 4: 147.
3. Biswal B, Yetkin FZ, Haughton VM, Hyde JS (1995): Functional connectivity in the motor cortex of resting human brain using echo-planar MRI. Magn Reson Med 34: 537-541.
4. Bluhm RL, Miller J, Lanius RA, Osuch EA, Boksman K, Neufeld RW, Theberge J, Schaefer B, Williamson P (2007): Spontaneous low-frequency fluctuations in the BOLD signal in schizophrenic patients: Anomalies in the default network. Schizophr Bull 33: 1004-1012.
5. Buckner RL, Andrews-Hanna JR, Schacter DL (2008): The brain's default network: Anatomy, function, and relevance to disease. Ann NY Acad Sci 1124: 1-38.
6. Bullmore ET, Frangou S, Murray RM (1997): The dysplastic net hypothesis: An integration of developmental and dysconnectivity theories of schizophrenia. Schizophr Res 28: 143-156.
7. Calhoun VD, Kiehl KA, Liddle PF, Pearlson GD (2004): Aberrant localization of synchronous hemodynamic activity in auditory cortex reliably characterizes schizophrenia. Biol Psychiatry 55: 842-849.
8. Cole DM, Smith SM, Beckmann CF (2010): Advances and pitfalls in the analysis and interpretation of resting-state FMRI data. Front Syst Neurosci 4: 8.
9. Cordes D, Haughton VM, Arfanakis K, Carew JD, Turski PA, Moritz CH, Quigley MA, Meyerand ME (2001): Frequencies contributing to functional connectivity in cerebral cortex in "resting-state" data. Am J Neuroradiol 22: 1326-1333.
10. Demirci O, Stevens MC, Andreasen NC, Michael A, Liu J, White T, Pearlson GD, Clark VP, Calhoun VD (2009): Investigation of relationships between fMRI brain networks in the spectral domain using ICA and Granger causality reveals distinct differences between schizophrenia patients and healthy controls. Neuroimage 46: 419-431.
11. Ellison-Wright I, Glahn DC, Laird AR, Thelen SM, Bullmore E (2008): The anatomy of first-episode and chronic schizophrenia: an anatomical likelihood estimation meta-analysis. Am J Psychiatry 165: 1015-1023.
12. Ellison-Wright I, Bullmore E (2009): Meta-analysis of diffusion tensor imaging studies in schizophrenia. Schizophr Res 108: 3-10.
13. Fornito A, Yucel M, Dean B, Wood SJ, Pantelis C (2009a) Anatomical abnormalities of the anterior cingulate cortex in schizophrenia: Bridging the gap between neuroimaging and neuropathology. Schizophr Bull 35: 973-993.
14. Fornito A, Yucel M, Patti J, Wood SJ, Pantelis C (2009b) Mapping grey matter reductions in schizophrenia: An anatomical likelihood estimation analysis of voxel-based morphometry studies. Schizophr Res 108: 104-113.
15. Fornito A, Bullmore ET (2010a): What can spontaneous fluctuations of the blood oxygenation-level-dependent signal tell us about psychiatric disorders? Curr Opin Psychiatry 23: 239-249.
16. Fornito A, Zalesky A, Bullmore ET (2010b): Network scaling effects in graph analytic studies of human resting-state FMRI data. Front Syst Neurosci 4: 22.
17. Fornito A, Yoon J, Zalesky A, Bullmore ET, Carter CS: General and specific functional connectivity disturbances in first-episode schizophrenia during cognitive control performance. Biol Psychiatry (in press).
18. Fornito A, Zalesky A, Bassett DS, Meunier D, Ellison-Wright I, Yucel M, Wood SJ, Shaw K, O'Connor J, Nertney D, Mowry BJ, Pantelis C, Bullmore ET (2011a) Genetic influences on cost-efficient organization of human cortical functional networks. J Neurosci 31: 3261-3270.
19. Fox MD, Snyder AZ, Vincent JL, Corbetta M, Van Essen DC, Raichle ME (2005): The human brain is intrinsically organized into dynamic, anticorrelated functional networks. Proc Natl Acad Sci USA 102: 9673-9678.
20. Fransson F (2005): Spontaneous low-frequency BOLD signal fluctuations: An fMRI investigation of resting-state default mode of brain function hypothesis. Hum Brain Mapp 26: 15-29.
21. Friston KJ (1994): Functional and effective connectivity in neuroimaging: A synthesis. Hum Brain Mapp 2: 56-78.
22. Friston KJ, Frith CD (1995): Schizophrenia: A disconnection syndrome? Clin Neurosci 3: 89-97.
23. Garrity AG, Pearlson GD, McKiernan K, Lloyd D, Kiehl KA, Calhoun VD (2007): Abberant "default mode" functional connectivity in schizophrenia. Am J Psychiatry 164: 450-457.
24. Girvan M, Newman MEJ (2002): Community structure in social and biological networks. Proc Natl Acad Sci USA 99: 7821-7826.
25. Glahn DC, Winkler AM, Kochunov P, Almasy L, Duggirala R, Carless MA, Curran JC, Olvera RL, Laird AR, Smith SM, Beckmann CF, Fox PT, Blangero J (2010): Genetic control over the resting brain. Proc Natl Acad Sci USA 107: 1223-1228.
26. Hampson M, Peterson BS, Skudlarski P, Gatenby JC, Gore JC (2002): Detection of functional connectivity using temporal correlations in MR images. Hum Brain Mapp 15: 247-262.
27. Harrison PJ (1999): The neuropathology of schizophrenia: A critical review of the data and their interpretation. Brain 122: 593-624.
28. Hayasaka S, Laurienti P (2009): Comparison of characteristics between region- and voxel-based network analyses in resting-state fMRI data. Neuroimage 50: 499-508.
29. Hayasaka S, Nichols TE (2004): Combining voxel intensity and cluster extent with permutation test framework. Neuroimage 23: 54-63.
30. He Y, Evans A (2010): Graph theoretical modeling of brain connectivity. Curr Opin Neurol 23: 341-350.
31. Hoptman MJ, Zuo XN, Butler PD, Javitt DC, D'Angelo D, Mauro CJ, Milham MP (2010): Amplitude of low-frequency oscillations in schizophrenia: A resting-state fMRI study. Schizophr Res 117: 13-20.
32. Jafri MJ, Pearlson GD, Stevens M, Calhoun VD (2008): A method for functional network connectivity among spatially independent resting-state components in schizophrenia. Neuroimage 39: 1666-1681.
33. Konrad A, Winterer G (2008): Disturbed structural connectivity in schizophrenia-primary factor in pathology or epiphenomenon? Schizophr Bull 34: 72-92.
34. Kubicki M, McCarley RW, Shenton ME (2005): Evidence for white matter abnormalities in schizophrenia. Curr Opin Psychiatry 18: 121-134.
35. Liu Y, Liang M, Zhou Y, He Y, Hao Y, Song M, Yu C, Liu H, Liu Z, Jiang T (2008): Disrupted small-world networks in schizophrenia. Brain 131: 945-961.
36. Liu H, Liu Z, Liang M, Hao Y, Tan L, Kuang F, Yi Y, Xu L, Jiang T (2006): Decreased regional homogeneity in schizophrenia: A resting state functional magentic resonance imaging study. Neuroreport 17: 19-22.
37. Liang M, Zhou Y, Jiang T, Liu Z, Tian L, Liu H, Hao Y (2006): Widespread functional disconnectivity in schizophrenia with resting-state functional magnetic resonance imaging. Neuroreport 17: 209-213.
38. Lynall ME, Bassett DS, Kerwin R, McKenna PJ, Kitzbichler M, Muller U, Bullmore E (2010): Functional connectivity and brain networks in schizophrenia. J Neurosci 30: 9477-9487.
39. Lui S, Li T, Deng W, Jiang L, Wu Q, Tang H, Yue Q, Huang X, Chan RC, Collier DA, Meda SA, Pearlson G, Mechelli A, Sweeney JA, Gong Q (2010): Short-term effects of antipsychotic treatment on cerebral function in drug-naive first-episode schizophrenia revealed by "resting state" functional magnetic resonance imaging. Arch Gen Psychiatry 67: 783-792.
40. McGlashan TH, Hoffman RE (2000): Schizophrenia as a disorder of developmentally reduced synaptic connectivity. Arch Gen Psychiatry 57: 637-648.
41. Meyer-Lindenberg A, Poline JB, Kohn PD, Holt JL, Egan MF, Weinberger DR, Berman KF (2001): Evidence for abnormal cortical functional connectivity during working memory in schizophrenia. Am J Psychiatry 158: 1809-1817.
42. Nelson H (1992): National Adult Reading Test (NART): Test Manual. Windsor, UK: National Foundation for Educational Research.
43. Nichols TE, Holmes AP (2001): Nonparametric permutation tests for functional neuroimaging: A primer with examples. Hum Brain Mapp 15: 1-25.
44. Onitsuka T, McCarley RW, Kuroki N, Dickey CC, Kubicki M, Demeo SS, Frumin M, Kikinis R, Jolesz FA, Shenton ME (2007): Occipital lobe gray matter volume in male patients with chronic schizophrenia: A quantitative MRI study. Schizophr Res 92: 197-206.
45. Rotarska-Jagiela A, van de Ven V, Oertel-Knochel V, Uhlhaas PJ, Vogeley K, Linden DEJ (2010): Resting-state functional network correlates of psychotic symptoms in schizophrenia. Schizophr Res 117: 21-30.
46. Rubinov M, Knock SA, Stam CJ, Micheloyannis S, Harris AWF, Williams LM, Breakspear M (2009): Small-world properties of nonlinear brain activity in schizophrenia. Hum Brain Mapp 30: 403-416.
47. Seeley WW, Crawford RK, Zhou J, Miller BL, Greicius MD (2009): Neurodegenerative diseases target large-scale human brain networks. Neuron 62: 42-52.
48. Sehatpour P, Dias EC, Butler PD, Revheim N, Guilfoyle DN, Foxe JJ, Javitt DC (2010): Impaired visual object processing across an occipital-frontal-hippocampal brain network in schizophrenia: An integrated neuroimaging study. Arch Gen Psychiatry 67: 772-782.
49. Smith S. Niazy R. Beckmann C, Miller K (2008): Resting state networks: Neither low-frequency nor anti-correlated? In: Proceedings of the 14th Annual Meeting of the Organization for Human Brain Mapping. Melbourne, Australia.
50. Smith SM, Fox PT, Miller KL, Glahn DC, Fox PM, Mackay CE, Filippini N, Watkins KE, Toro R, Laird AR, Beckmann CF (2009): Correspondence of the brain's functional architecture during activation and rest. Proc Natl Acad Sci USA 106: 13040-13045.
51. Smith SM, Miller KL, Salimi-Korshidi G, Webster M, Beckmann CF, Nichols TE, Ramsey JD, Woolrich MD (2011): Network modelling methods for FMRI. Neuroimage 54: 875-891.
52. Stephan KE, Friston KJ, Frith CD (2009): Dysconnection is schizophrenia: From abnormal synaptic plasticity to failures of self-monitoring. Schizophr Bull 35: 509-527.
53. Suckling J, Long C, Triantafyllou C, Brammer M, Bullmore E (2006): Variable precision registration via wavelets: Optimal spatial scales for inter-subject registration of functional MRI. Neuroimage 31: 197-208.
54. Takahashi T, Wood SJ, Yung AR, Phillips LJ, Soulsby B, McGorry PD, Tanino R, Zhou SY, Suzuki M, Velakoulis D, Pantelis C (2009): Insular cortex gray matter changes in individuals at ultra-high-risk of developing psychosis. Schizophr Res 111: 94-102.
55. Tost H, Braus DF, Hakimi S, Ruf M, Vollmert C, Hohn F, Meyer-Lindenberg A (2010): Acute D2 receptor blockade induces rapid, reversible remodeling in human cortical-striatal circuits. Nat Neurosci 13: 920-922.
56. Van den Heuvel MP, Stam CJ, Boersma M, Hulshoff Pol HE (2008): Small-world and scale-free organization of voxel-based resting-state functional connectivity in the human brain. Neuroimage 43: 528-539.
57. Wang J, Zuo X, He Y (2010): Graph-based network analysis of resting-state functional MRI. Front Syst Neurosci 4: 16.
58. Weinberger DR, Berman KF, Suddath R, Torrey EF (1992): Evidence of dysfunction of a prefrontal-limbic network in schizophrenia: A magnetic resonance imaging and regional cerebral blood flow study of discordant monozygotic twins. Am J Psychiatry 149: 890-897.
59. White T, Magnotta VA, Bockholt HJ, Williams S, Wallace S, Ehrlich S, Mueller BA, Ho BC, Jung RE, Clark VP, Lauriello J, Bustillo JR, Schulz SC, Gollub RL, Andreasen NC, Calhoun VD, Lim KO (2011): Global white matter abnormalities in schizophrenia: A multisite diffusion tensor imaging study. Schizophr Bull 37: 222-232.
60. Whitfield-Gabrieli S, Thermenos HW, Milanovic S, Tsuang MT, Faraone SV, McCarley RW, Shenton ME, Green AI, Nieto-Castanon A, LaViolette P, Wojcik J, Gabrieli JD, Seidman LJ (2009): Hyperactivity and hyperconnectivity of the default network in schizophrenia and in first-degree relatives of persons with schizophrenia. Proc Natl Acad Sci USA 106: 1279-1284.
61. Wig GS, Schlaggar BL, Petersen SE (2011): Concepts and principles in the analysis of brain networks. Ann N Y Acad Sci 1224: 126-146.
62. Yoon JH, Maddock RJ, Rokem A, Silver MA, Minzenberg MJ, Ragland JD, Carter CS (2010): GABA concentration is reduced in visual cortex in schizophrenia and correlates with orientation-specific surround suppression. J Neurosci 30: 3777-3781.
63. Zalesky A, Fornito A, Seal ML, Cocchi L, Westin CF, Bullmore E, Egan GF, Pantelis C (2011): Disrupted axonal fiber connectivity in schizophrenia. Biol Psychiatry 69: 80-89.
64. Zalesky A, Fornito A, Harding IH, Cocchi L, Yucel M, Pantelis C, Bullmore ET (2010a): Whole-brain anatomical networks: Does the choice of nodes matter? NeuroImage 50: 970-983.
65. Zalesky A, Fornito A, Bullmore ET (2010b) Network-based statistic: Identifying differences in brain networks. Neuroimage 53: 1197-1207.
66. Zang Y, Jiang T, Lu Y, He Y, Tian L (2004): Regional homogeneity approach to fMRI data analysis. Neuroimage 22: 394-400.
67. Zang Y-F, He Y, Zhu C-Z, Cao Q-J, Sui M-Q, Liang M, Tian L-X, Jiang T-Z, Wang Y-F (2007): Altered baseline brain activity in children with ADHD revealed by resting-state functional MRI. Brain Dev 29: 83-91.
68. Zhou Y, Liang M, Tian L, Wang K, Hao Y, Liu H, Liu Z, Jiang T (2007): Functional disintegration in paranoid schizophrenia using resting-state fMRI. Schizophr Res 97: 194-205.