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Volumn 67, Issue 11, 2012, Pages 2673-2681

In vitro evaluation of tobramycin and aztreonam versus Pseudomonas aeruginosa biofilms on cystic fibrosis-derived human airway epithelial cells

Author keywords

AZLI; Co culture; Monotherapy; Tolerance

Indexed keywords

AZTREONAM LYSINE; EXOPOLYSACCHARIDE; TOBRAMYCIN;

EID: 84867615387     PISSN: 03057453     EISSN: 14602091     Source Type: Journal    
DOI: 10.1093/jac/dks296     Document Type: Article
Times cited : (57)

References (45)
  • 1
    • 0024424270 scopus 로고
    • Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA
    • Riordan JR, Rommens JM, Kerem B et al. Identification of the cystic fibrosis gene: cloning and characterization of complementary DNA. Science 1989; 245: 1066-73.
    • (1989) Science , vol.245 , pp. 1066-1073
    • Riordan, J.R.1    Rommens, J.M.2    Kerem, B.3
  • 2
    • 0024423668 scopus 로고
    • Identification of the cystic fibrosis gene: genetic analysis
    • Kerem B, Rommens JM, Buchanan JA et al. Identification of the cystic fibrosis gene: genetic analysis. Science 1989; 245: 1073-80.
    • (1989) Science , vol.245 , pp. 1073-1080
    • Kerem, B.1    Rommens, J.M.2    Buchanan, J.A.3
  • 3
    • 4544330253 scopus 로고    scopus 로고
    • Cystic Fibrosis Foundation. (2 July 2012, date last accessed)
    • Cystic Fibrosis Foundation. Patient Registry Annual Data Report 2010. http://www.cff.org/UploadedFiles/LivingWithCF/CareCenterNetwork/PatientRegistry/2010-Patient-Registry-Report.pdf (2 July 2012, date last accessed).
    • (2010) Patient Registry Annual Data Report
  • 4
    • 23644451772 scopus 로고    scopus 로고
    • Infection and inflammation in cystic fibrosis: a short review
    • Heijerman H. Infection and inflammation in cystic fibrosis: a short review. J Cyst Fibros 2005; 4 Suppl 2: 3-5.
    • (2005) J Cyst Fibros , vol.4 , Issue.SUPPL. 2 , pp. 3-5
    • Heijerman, H.1
  • 5
    • 69449107153 scopus 로고    scopus 로고
    • Tobramycin and FDA-approved iron chelators eliminate Pseudomonas aeruginosa biofilms on cystic fibrosis cells
    • Moreau-Marquis S, O'Toole GA, Stanton BA. Tobramycin and FDA-approved iron chelators eliminate Pseudomonas aeruginosa biofilms on cystic fibrosis cells. Am J Respir Cell Mol Biol 2009; 41: 305-13.
    • (2009) Am J Respir Cell Mol Biol , vol.41 , pp. 305-313
    • Moreau-Marquis, S.1    O'Toole, G.A.2    Stanton, B.A.3
  • 6
    • 66849142486 scopus 로고    scopus 로고
    • Aerosol antibiotics in cystic fibrosis
    • Geller DE. Aerosol antibiotics in cystic fibrosis. Respir Care 2009; 54: 658-70.
    • (2009) Respir Care , vol.54 , pp. 658-670
    • Geller, D.E.1
  • 7
    • 0029814366 scopus 로고    scopus 로고
    • Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia
    • Govan JR, Deretic V. Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia. Microbiol Rev 1996; 60: 539-74.
    • (1996) Microbiol Rev , vol.60 , pp. 539-574
    • Govan, J.R.1    Deretic, V.2
  • 8
    • 0034641962 scopus 로고    scopus 로고
    • Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms
    • Singh PK, Schaefer AL, Parsek MR et al. Quorum-sensing signals indicate that cystic fibrosis lungs are infected with bacterial biofilms. Nature 2000; 407: 762-4.
    • (2000) Nature , vol.407 , pp. 762-764
    • Singh, P.K.1    Schaefer, A.L.2    Parsek, M.R.3
  • 9
    • 0035014383 scopus 로고    scopus 로고
    • Mechanisms of biofilm resistance to antimicrobial agents
    • Mah TF, O'Toole GA. Mechanisms of biofilm resistance to antimicrobial agents. Trends Microbiol 2001; 9: 34-9.
    • (2001) Trends Microbiol , vol.9 , pp. 34-39
    • Mah, T.F.1    O'Toole, G.A.2
  • 10
    • 79953262396 scopus 로고    scopus 로고
    • Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis
    • Hoiby N. Recent advances in the treatment of Pseudomonas aeruginosa infections in cystic fibrosis. BMC Med 2011; 9: 32.
    • (2011) BMC Med , vol.9 , pp. 32
    • Hoiby, N.1
  • 11
    • 77952231620 scopus 로고    scopus 로고
    • Optimal airway antimicrobial therapy for cystic fibrosis: the role of inhaled aztreonam lysine
    • Elborn JS, Henig NR. Optimal airway antimicrobial therapy for cystic fibrosis: the role of inhaled aztreonam lysine. Expert Opin Pharmacother 2010; 11: 1373-85.
    • (2010) Expert Opin Pharmacother , vol.11 , pp. 1373-1385
    • Elborn, J.S.1    Henig, N.R.2
  • 12
    • 0020077544 scopus 로고
    • Azthreonam (SQ 26 776), a synthetic monobactam specifically active against aerobic Gramnegative bacteria
    • Sykes RB, Bonner DP, Bush K et al. Azthreonam (SQ 26,776), a synthetic monobactam specifically active against aerobic Gramnegative bacteria. Antimicrob Agents Chemother 1982; 21: 85-92.
    • (1982) Antimicrob Agents Chemother , vol.21 , pp. 85-92
    • Sykes, R.B.1    Bonner, D.P.2    Bush, K.3
  • 13
    • 55549137086 scopus 로고    scopus 로고
    • Inhaled aztreonam lysine for chronic airway Pseudomonas aeruginosa in cystic fibrosis
    • McCoy KS, Quittner AL, Oermann CM et al. Inhaled aztreonam lysine for chronic airway Pseudomonas aeruginosa in cystic fibrosis. Am J Respir Crit Care Med 2008; 178: 921-8.
    • (2008) Am J Respir Crit Care Med , vol.178 , pp. 921-928
    • McCoy, K.S.1    Quittner, A.L.2    Oermann, C.M.3
  • 14
    • 65949124667 scopus 로고    scopus 로고
    • Efficacy and safety of inhaled aztreonam lysine for airway Pseudomonas in cystic fibrosis
    • Retsch-Bogart GZ, Quittner AL, Gibson RL et al. Efficacy and safety of inhaled aztreonam lysine for airway Pseudomonas in cystic fibrosis. Chest 2009; 135: 1223-32.
    • (2009) Chest , vol.135 , pp. 1223-1232
    • Retsch-Bogart, G.Z.1    Quittner, A.L.2    Gibson, R.L.3
  • 15
    • 78449294500 scopus 로고    scopus 로고
    • An 18-month study of the safety and efficacy of repeated courses of inhaled aztreonam lysine in cystic fibrosis
    • Oermann CM, Retsch-Bogart GZ, Quittner AL et al. An 18-month study of the safety and efficacy of repeated courses of inhaled aztreonam lysine in cystic fibrosis. Pediatr Pulmonol 2010; 45: 1121-34.
    • (2010) Pediatr Pulmonol , vol.45 , pp. 1121-1134
    • Oermann, C.M.1    Retsch-Bogart, G.Z.2    Quittner, A.L.3
  • 16
    • 77955047596 scopus 로고    scopus 로고
    • Aztreonam lysine: a novel inhalational antibiotic for cystic fibrosis
    • Parkins MD, Elborn JS. Aztreonam lysine: a novel inhalational antibiotic for cystic fibrosis. Exp Rev Respir Med 2010; 4: 435-44.
    • (2010) Exp Rev Respir Med , vol.4 , pp. 435-444
    • Parkins, M.D.1    Elborn, J.S.2
  • 17
    • 42149086134 scopus 로고    scopus 로고
    • In vitro analysis of tobramycin-treated Pseudomonas aeruginosa biofilms on cystic fibrosis-derived airway epithelial cells
    • Anderson GG, Moreau-Marquis S, Stanton BA et al. In vitro analysis of tobramycin-treated Pseudomonas aeruginosa biofilms on cystic fibrosis-derived airway epithelial cells. Infect Immun 2008; 76: 1423-33.
    • (2008) Infect Immun , vol.76 , pp. 1423-1433
    • Anderson, G.G.1    Moreau-Marquis, S.2    Stanton, B.A.3
  • 18
    • 47049126626 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa biofilm formation in the cystic fibrosis airway
    • Moreau-Marquis S, Stanton BA, O'Toole GA. Pseudomonas aeruginosa biofilm formation in the cystic fibrosis airway. Pulm Pharmacol Ther 2008; 21: 595-9.
    • (2008) Pulm Pharmacol Ther , vol.21 , pp. 595-599
    • Moreau-Marquis, S.1    Stanton, B.A.2    O'Toole, G.A.3
  • 19
  • 20
    • 3042735895 scopus 로고    scopus 로고
    • Two genetic loci produce distinct carbohydraterich structural components of the Pseudomonas aeruginosa biofilm matrix
    • Friedman L, Kolter R. Two genetic loci produce distinct carbohydraterich structural components of the Pseudomonas aeruginosa biofilm matrix. J Bacteriol 2004; 186: 4457-65.
    • (2004) J Bacteriol , vol.186 , pp. 4457-4465
    • Friedman, L.1    Kolter, R.2
  • 21
    • 0032698389 scopus 로고    scopus 로고
    • Negative control of flagellum synthesis in Pseudomonas aeruginosa is modulated by the alternative sigma factor AlgT (AlgU)
    • Garrett ES, Perlegas D, Wozniak DJ. Negative control of flagellum synthesis in Pseudomonas aeruginosa is modulated by the alternative sigma factor AlgT (AlgU). J Bacteriol 1999; 181: 7401-4.
    • (1999) J Bacteriol , vol.181 , pp. 7401-7404
    • Garrett, E.S.1    Perlegas, D.2    Wozniak, D.J.3
  • 22
    • 33751579323 scopus 로고    scopus 로고
    • Analysis of Pseudomonas aeruginosa conditional Psl variants reveals roles for the Psl polysaccharide in adhesion and maintaining biofilm structure postattachment
    • Ma L, Jackson KD, Landry RM et al. Analysis of Pseudomonas aeruginosa conditional Psl variants reveals roles for the Psl polysaccharide in adhesion and maintaining biofilm structure postattachment. J Bacteriol 2006; 188: 8213-21.
    • (2006) J Bacteriol , vol.188 , pp. 8213-8221
    • Ma, L.1    Jackson, K.D.2    Landry, R.M.3
  • 23
    • 84864391454 scopus 로고    scopus 로고
    • Pseudomonas aeruginosa exopolysaccharide Psl promotes resistance to the biofilm inhibitor polysorbate 80
    • doi:10.1128/ AAC.00373-12
    • Zegans ME, Wozniak D, Griffin E et al. Pseudomonas aeruginosa exopolysaccharide Psl promotes resistance to the biofilm inhibitor polysorbate 80. Antimicrob Agents Chemother 2012; doi:10.1128/ AAC.00373-12.
    • (2012) Antimicrob Agents Chemother
    • Zegans, M.E.1    Wozniak, D.2    Griffin, E.3
  • 24
    • 0000361721 scopus 로고
    • The identification of atypical strains of Pseudomonas aeruginosa
    • Wahba AH, Darrell JH. The identification of atypical strains of Pseudomonas aeruginosa. J Gen Microbiol 1965; 38: 329-42.
    • (1965) J Gen Microbiol , vol.38 , pp. 329-342
    • Wahba, A.H.1    Darrell, J.H.2
  • 25
    • 0036304163 scopus 로고    scopus 로고
    • Pharmacokinetics and bioavailability of aerosolized tobramycin in cystic fibrosis
    • Geller DE, Pitlick WH, Nardella PA et al. Pharmacokinetics and bioavailability of aerosolized tobramycin in cystic fibrosis. Chest 2002; 122: 219-26.
    • (2002) Chest , vol.122 , pp. 219-226
    • Geller, D.E.1    Pitlick, W.H.2    Nardella, P.A.3
  • 26
    • 0036272055 scopus 로고    scopus 로고
    • Isolation of CF cell lines corrected at DF508-CFTR locus by SFHR-mediated targeting
    • Bruscia E, Sangiuolo F, Sinibaldi P et al. Isolation of CF cell lines corrected at DF508-CFTR locus by SFHR-mediated targeting. Gene Ther 2002; 9: 683-5.
    • (2002) Gene Ther , vol.9 , pp. 683-685
    • Bruscia, E.1    Sangiuolo, F.2    Sinibaldi, P.3
  • 27
    • 0027928745 scopus 로고
    • CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells
    • Cozens AL, Yezzi MJ, Kunzelmann K et al. CFTR expression and chloride secretion in polarized immortal human bronchial epithelial cells. Am J Respir Cell Mol Biol 1994; 10: 38-47.
    • (1994) Am J Respir Cell Mol Biol , vol.10 , pp. 38-47
    • Cozens, A.L.1    Yezzi, M.J.2    Kunzelmann, K.3
  • 29
    • 49049089612 scopus 로고    scopus 로고
    • The DF508-CFTR mutation results in increased biofilm formation by Pseudomonas aeruginosa by increasing iron availability
    • Moreau-Marquis S, Bomberger JM, Anderson GG et al. The DF508-CFTR mutation results in increased biofilm formation by Pseudomonas aeruginosa by increasing iron availability. Am J Physiol Lung Cell Mol Physiol 2008; 295: L25-37.
    • (2008) Am J Physiol Lung Cell Mol Physiol , vol.295
    • Moreau-Marquis, S.1    Bomberger, J.M.2    Anderson, G.G.3
  • 30
    • 0344011974 scopus 로고    scopus 로고
    • A genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance
    • Mah TF, Pitts B, Pellock B et al. A genetic basis for Pseudomonas aeruginosa biofilm antibiotic resistance. Nature 2003; 426: 306-10.
    • (2003) Nature , vol.426 , pp. 306-310
    • Mah, T.F.1    Pitts, B.2    Pellock, B.3
  • 31
    • 33750579748 scopus 로고    scopus 로고
    • Does Pseudomonas aeruginosa use intercellular signalling to build biofilm communities?
    • Kirisits MJ, Parsek MR. Does Pseudomonas aeruginosa use intercellular signalling to build biofilm communities? Cell Microbiol 2006; 8: 1841-9.
    • (2006) Cell Microbiol , vol.8 , pp. 1841-1849
    • Kirisits, M.J.1    Parsek, M.R.2
  • 33
    • 0031468189 scopus 로고    scopus 로고
    • Ceftazidime, gentamicin, and rifampicin, in combination, kill biofilms of mucoid Pseudomonas aeruginosa
    • Ghani M, Soothill JS. Ceftazidime, gentamicin, and rifampicin, in combination, kill biofilms of mucoid Pseudomonas aeruginosa. Can J Microbiol 1997; 43: 999-1004.
    • (1997) Can J Microbiol , vol.43 , pp. 999-1004
    • Ghani, M.1    Soothill, J.S.2
  • 34
    • 70349690322 scopus 로고    scopus 로고
    • Combination antibiotic susceptibility of biofilm-grown Burkholderia cepacia and Pseudomonas aeruginosa isolated from patients with pulmonary exacerbations of cystic fibrosis
    • Dales L, Ferris W, Vandemheen K et al. Combination antibiotic susceptibility of biofilm-grown Burkholderia cepacia and Pseudomonas aeruginosa isolated from patients with pulmonary exacerbations of cystic fibrosis. Eur J Clin Microbiol Infect Dis 2009; 28: 1275-9.
    • (2009) Eur J Clin Microbiol Infect Dis , vol.28 , pp. 1275-1279
    • Dales, L.1    Ferris, W.2    Vandemheen, K.3
  • 35
    • 78349232036 scopus 로고    scopus 로고
    • Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa
    • Herrmann G, Yang L, Wu H et al. Colistin-tobramycin combinations are superior to monotherapy concerning the killing of biofilm Pseudomonas aeruginosa. J Infect Dis 2010; 202: 1585-92.
    • (2010) J Infect Dis , vol.202 , pp. 1585-1592
    • Herrmann, G.1    Yang, L.2    Wu, H.3
  • 36
    • 84856346934 scopus 로고    scopus 로고
    • In vitro combination effects of aztreonam and aminoglycoside against multidrug-resistant Pseudomonas aeruginosa in Japan
    • Araoka H, Baba M, Tateda K et al. In vitro combination effects of aztreonam and aminoglycoside against multidrug-resistant Pseudomonas aeruginosa in Japan. Jpn J Infect Dis 2012; 65: 84-7.
    • (2012) Jpn J Infect Dis , vol.65 , pp. 84-87
    • Araoka, H.1    Baba, M.2    Tateda, K.3
  • 37
    • 0029783759 scopus 로고    scopus 로고
    • Sigma factor-anti-sigma factor interaction in alginate synthesis: inhibition of AlgT by MucA
    • Xie ZD, Hershberger CD, Shankar S et al. Sigma factor-anti-sigma factor interaction in alginate synthesis: inhibition of AlgT by MucA. J Bacteriol 1996; 178: 4990-6.
    • (1996) J Bacteriol , vol.178 , pp. 4990-4996
    • Xie, Z.D.1    Hershberger, C.D.2    Shankar, S.3
  • 38
    • 0027267656 scopus 로고
    • Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients
    • Martin DW, Schurr MJ, Mudd MH et al. Mechanism of conversion to mucoidy in Pseudomonas aeruginosa infecting cystic fibrosis patients. Proc Natl Acad Sci USA 1993; 90: 8377-81.
    • (1993) Proc Natl Acad Sci USA , vol.90 , pp. 8377-8381
    • Martin, D.W.1    Schurr, M.J.2    Mudd, M.H.3
  • 39
    • 78049393223 scopus 로고    scopus 로고
    • Activation of the Pseudomonas aeruginosa AlgU regulon through mucA mutation inhibits cyclic AMP/Vfr signaling
    • Jones AK, Fulcher NB, Balzer GJ et al. Activation of the Pseudomonas aeruginosa AlgU regulon through mucA mutation inhibits cyclic AMP/Vfr signaling. J Bacteriol 2010; 192: 5709-17.
    • (2010) J Bacteriol , vol.192 , pp. 5709-5717
    • Jones, A.K.1    Fulcher, N.B.2    Balzer, G.J.3
  • 40
    • 79953165038 scopus 로고    scopus 로고
    • Aminoglycoside resistance of Pseudomonas aeruginosa biofilms modulated by extracellular polysaccharide
    • Khan W, Bernier SP, Kuchma SL et al. Aminoglycoside resistance of Pseudomonas aeruginosa biofilms modulated by extracellular polysaccharide. Int Microbiol 2010; 13: 207-12.
    • (2010) Int Microbiol , vol.13 , pp. 207-212
    • Khan, W.1    Bernier, S.P.2    Kuchma, S.L.3
  • 41
    • 73849128431 scopus 로고    scopus 로고
    • In vitro pharmacodynamics of levofloxacin and other aerosolized antibiotics under multiple conditions relevant to chronic pulmonary infection in cystic fibrosis
    • King P, Lomovskaya O, Griffith DC et al. In vitro pharmacodynamics of levofloxacin and other aerosolized antibiotics under multiple conditions relevant to chronic pulmonary infection in cystic fibrosis. Antimicrob Agents Chemother 2010; 54: 143-8.
    • (2010) Antimicrob Agents Chemother , vol.54 , pp. 143-148
    • King, P.1    Lomovskaya, O.2    Griffith, D.C.3
  • 42
    • 0027287651 scopus 로고
    • Efficacy of aerosolized tobramycin in patients with cystic fibrosis
    • Ramsey BW, Dorkin HL, Eisenberg JD et al. Efficacy of aerosolized tobramycin in patients with cystic fibrosis. N Engl J Med 1993; 328: 1740-6.
    • (1993) N Engl J Med , vol.328 , pp. 1740-1746
    • Ramsey, B.W.1    Dorkin, H.L.2    Eisenberg, J.D.3
  • 43
    • 0033531143 scopus 로고    scopus 로고
    • Intermittent administration of inhaled tobramycin in patients with cystic fibrosis Cystic Fibrosis Inhaled Tobramycin Study Group
    • Ramsey BW, Pepe MS, Quan JM et al. Intermittent administration of inhaled tobramycin in patients with cystic fibrosis. Cystic Fibrosis Inhaled Tobramycin Study Group. N Engl J Med 1999; 340: 23-30.
    • (1999) N Engl J Med , vol.340 , pp. 23-30
    • Ramsey, B.W.1    Pepe, M.S.2    Quan, J.M.3
  • 44
    • 78651412529 scopus 로고    scopus 로고
    • Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: the EAGER trial
    • Konstan MW, Flume PA, Kappler M et al. Safety, efficacy and convenience of tobramycin inhalation powder in cystic fibrosis patients: the EAGER trial. J Cyst Fibros 2011; 10: 54-61.
    • (2011) J Cyst Fibros , vol.10 , pp. 54-61
    • Konstan, M.W.1    Flume, P.A.2    Kappler, M.3
  • 45
    • 0031879743 scopus 로고    scopus 로고
    • Resistance mechanisms in Pseudomonas aeruginosa and other nonfermentative Gram-negative bacteria
    • Hancock RE. Resistance mechanisms in Pseudomonas aeruginosa and other nonfermentative Gram-negative bacteria. Clin Infect Dis 1998; 27 Suppl 1: S93-9.
    • (1998) Clin Infect Dis , vol.27 , Issue.SUPPL. 1
    • Hancock, R.E.1


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