Telomerase activity is sensitive to subtle perturbations of the TLC1 pseudoknot 3′ stem and tertiary structure

Journal of Molecular Biology

Volumn 423, Issue 5, 2012, Pages 719-735

  Liu, Fei ^a   Theimer, Carla A ^a  

^a STATE UNIVERSITY OF NEW YORK   (United States)

Author keywords

2 OH ribose substitutions; backbone conformation; circular dichroism spectroscopy; telomerase RNA pseudoknot; thermodynamics

Indexed keywords

FUNGAL PROTEIN; RIBOSE; TELOMERASE; TLC1 PROTEIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; CATALYSIS; CIRCULAR DICHROISM; ENZYME ACTIVITY; GEL ELECTROPHORESIS; KLUYVEROMYCES LACTIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN TERTIARY STRUCTURE; THERMODYNAMICS;

CILIOPHORA; KLUYVEROMYCES LACTIS; SACCHAROMYCES CEREVISIAE; VERTEBRATA;

EID: 84867583317     PISSN: 00222836     EISSN: 10898638     Source Type: Journal    
DOI: 10.1016/j.jmb.2012.08.025     Document Type: Article

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