MRPS27 is a pentatricopeptide repeat domain protein required for the translation of mitochondrially encoded proteins

FEBS Letters

Volumn 586, Issue 20, 2012, Pages 3555-3561

  Davies, Stefan M K ^a   Lopez Sanchez, Maria I G ^a   Narsai, Reena ^b   Shearwood, Anne Marie J ^a   Razif, Muhammad F M ^a   Small, Ian D ^b   Whelan, James ^b   Rackham, Oliver ^a   Filipovska, Aleksandra ^a  

^a UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

^b UNIVERSITY OF WESTERN AUSTRALIA   (Australia)

Author keywords

Pentatricopeptide repeat domain; RNA; RNA binding protein

Indexed keywords

CYTOCHROME C OXIDASE; MESSENGER RNA; MITOCHONDRIAL PROTEIN; MITOCHONDRIAL RIBOSOMAL PROTEIN OF THE SMALL SUBUNIT 27; MITOCHONDRIAL RNA; RIBOSOME PROTEIN; RNA 12S; TRANSFER RNA; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; ENZYME ACTIVITY; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; HUMAN; HUMAN CELL; MITOCHONDRIAL GENE; MITOCHONDRIAL RESPIRATION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; RNA METABOLISM; RNA PROCESSING; RNA STABILITY; TRANSCRIPTION REGULATION; TRANSLATION REGULATION;

CELL LINE, TUMOR; ELECTRON TRANSPORT COMPLEX IV; HUMANS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PROTEIN BIOSYNTHESIS; PROTEIN STRUCTURE, TERTIARY; REPETITIVE SEQUENCES, AMINO ACID; RIBOSOMAL PROTEINS; RIBOSOME SUBUNITS, SMALL; RNA, MESSENGER;

MAMMALIA;

EID: 84867580040     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2012.07.043     Document Type: Article

References (41)

1. J. Smeitink, L. van den Heuvel, and S. DiMauro The genetics and pathology of oxidative phosphorylation Nat. Rev. Genet. 2 2001 342 352
2. E.A. Shoubridge Nuclear genetic defects of oxidative phosphorylation Hum. Mol. Genet. 10 2001 2277 2284
3. Y. Aloni, and G. Attardi Symmetrical In Vivo Transcription of Mitochondrial DNA in HeLa Cells Proc. Natl. Acad. Sci. USA 68 1971 1757 1761
4. W.I. Murphy, B. Attardi, C. Tu, and G. Attardi Evidence for complete symmetrical transcription in vivo of mitochondrial DNA in HeLa cells J. Mol. Biol. 99 1975 809 814
5. J. Montoya, T. Christianson, D. Levens, M. Rabinowitz, and G. Attardi Identification of initiation sites for heavy-strand and light-strand transcription in human mitochondrial DNA Proc. Natl. Acad. Sci. USA 79 1982 7195 7199
6. T.R. Mercer The human mitochondrial transcriptome Cell 146 2011 645 658
7. DJ. Pagliarini A mitochondrial protein compendium elucidates complex I disease biology Cell 134 2008 112 123
8. L.K. Ostronoff, J.M. Izquierdo, J.A. Enriquez, J. Montoya, and J.M. Cuezva Transient activation of mitochondrial translation regulates the expression of the mitochondrial genome during mammalian mitochondrial differentiation Biochem. J. 316 1996 183 191
9. T.D. Fox Translational control of endogenous and recoded nuclear genes in yeast mitochondria: regulation and membrane targeting Experientia 52 1996 1130 1135
10. E.C. Koc, and L.L. Spremulli RNA-binding proteins of mammalian mitochondria Mitochondrion 2 2003 277 291
11. B.E. Christian, and L.L. Spremulli Mechanism of protein biosynthesis in mammalian mitochondria Biochim. Biophys. Acta 2011
12. P. Smits, J.A. Smeitink, L.P. van den Heuvel, M.A. Huynen, and TJ. Ettema Reconstructing the evolution of the mitochondrial ribosomal proteome Nucleic Acids Res. 35 2007 4686 4703
13. T. Suzuki, M. Terasaki, C. Takemoto-Hori, T. Hanada, T. Ueda, A. Wada, and K. Watanabe Proteomic analysis of the mammalian mitochondrial ribosome. Identification of protein components in the 28 S small subunit J. Biol. Chem. 276 2001 33181 33195
14. M.R. Sharma, E.C. Koc, P.P. Datta, T.M. Booth, L.L. Spremulli, and R.K. Agrawal Structure of the mammalian mitochondrial ribosome reveals an expanded functional role for its component proteins Cell 115 2003 97 108
15. C. Schmitz-Linneweber, and I. Small Pentatricopeptide repeat proteins: a socket set for organelle gene expression Trends Plant Sci. 13 2008 663 670
16. O. Rackham, and A. Filipovska The role of mammalian PPR domain proteins in the regulation of mitochondrial gene expression Biochim. Biophys. Acta 2011 10.1016/j.bbagrm.2011.10.007
17. R.N. Lightowlers, and Z.M. Chrzanowska-Lightowlers PPR (pentatricopeptide repeat) proteins in mammals: important aids to mitochondrial gene expression Biochem. J. 416 2008 e5 e6
18. B. Ruzzenente LRPPRC is necessary for polyadenylation and coordination of translation of mitochondrial mRNAs EMBO J. 31 2011 443 456
19. F. Sasarman, C. Brunel-Guitton, H. Antonicka, T. Wai, and E.A. Shoubridge LRPPRC and SLIRP interact in a ribonucleoprotein complex that regulates posttranscriptional gene expression in mitochondria Mol. Biol. Cell 21 2010 1315 1323
20. F. Xu, J.B. Addis, J.M. Cameron, and B.H. Robinson Lrpprc mutation suppresses cytochrome oxidase activity by altering mitochondrial RNA transcript stability in a mouse model Biochem. J. 441 2011 275 283
21. F. Xu Disruption of a mitochondrial RNA-binding protein gene results in decreased cytochrome b expression and a marked reduction in ubiquinol-cytochrome c reductase activity in mouse heart mitochondria Biochem. J. 416 2008 15 26
22. S.M. Davies, O. Rackham, A.M. Shearwood, K.L. Hamilton, R. Narsai, J. Whelan, and A. Filipovska Pentatricopeptide repeat domain protein 3 associates with the mitochondrial small ribosomal subunit and regulates translation FEBS Lett. 583 2009 1853 1858
23. O. Rackham, S.M. Davies, A.M. Shearwood, K.L. Hamilton, J. Whelan, and A. Filipovska Pentatricopeptide repeat domain protein 1 lowers the levels of mitochondrial leucine tRNAs in cells Nucleic Acids Res. 37 2009 5859 5867
24. M.I. Sanchez RNA processing in human mitochondria Cell Cycle 10 2011 2904 2916
25. I. Kuhl, L. Dujeancourt, M. Gaisne, CJ. Herbert, and N. Bonnefoy A genome wide study in fission yeast reveals nine PPR proteins that regulate mitochondrial gene expression Nucleic Acids Res. 39 2011 8029 8041
26. T. Shikanai RNA editing in plant organelles: machinery, physiological function and evolution Cell. Mol. Life Sci. 63 2006 698 708
27. T. Burckstummer, K.L. Bennett, A. Preradovic, G. Schutze, O. Hantschel, G. Superti-Furga, and A. Bauch An efficient tandem affinity purification procedure for interaction proteomics in mammalian cells Nat. Methods 3 2006 1013 1019
28. M.D. Metodiev Methylation of 12S rRNA is necessary for in vivo stability of the small subunit of the mammalian mitochondrial ribosome Cell Metab. 9 2009 386 397
29. R. Richter A functional peptidyl-tRNA hydrolase, ICT1, has been recruited into the human mitochondrial ribosome EMBO J. 29 2010 1116 1125
30. H. Schagger Native electrophoresis for isolation of mitochondrial oxidative phosphorylation complexes Methods Enzymol. 260 1995 190 202
31. A.M. James, Y.-H. Wei, C.-Y. Pang, and M.P. Murphy Altered mitochondrial function in fibroblasts containing MELAS or MERRF mitochondrial DNA mutations Biochem. J. 318 1996 401 407
32. M. Emdadul Haque, D. Grasso, C. Miller, L.L. Spremulli, and A. Saada The effect of mutated mitochondrial ribosomal proteins S16 and S22 on the assembly of the small and large ribosomal subunits in human mitochondria Mitochondrion 8 2008 254 261
33. E. Cavdar Koc, A. Ranasinghe, W. Burkhart, K. Blackburn, H. Koc, A. Moseley, and L.L. Spremulli A new face on apoptosis: death-associated protein 3 and PDCD9 are mitochondrial ribosomal proteins FEBS Lett. 492 2001 166 170
34. T. Tang, B. Zheng, S.H. Chen, A.N. Murphy, K. Kudlicka, H. Zhou, and M.G. Farquhar hNOAl interacts with complex I and DAP3 and regulates mitochondrial respiration and apoptosis J. Biol. Chem. 284 2009 5414 5424
35. S. Dennerlein, A. Rozanska, M. Wydro, Z.M. Chrzanowska-Lightowlers, and R.N. Lightowlers Human ERAL1 is a mitochondrial RNA chaperone involved in the assembly of the 28S small mitochondrial ribosomal subunit Biochem. J. 430 2010 551 558
36. Rackham, O., Mercer, T.R. and Filipovska, A. (2012). The human mitochondrial transcriptome and theRNA-binding proteins that regulate its expression. Wiley Interdiscip Rev RNA. doi: http://dx.doi.org/10.1002/wrna.1128.
37. W. Weraarpachai Mutation in TACO1, encoding a translational activator of COX I, results in cytochrome c oxidase deficiency and late-onset Leigh syndrome Nat. Genet. 41 2009 833 837
38. F. Xu, C. Morin, G. Mitchell, C. Ackerley, and B.H. Robinson The role of the LRPPRC (leucine-rich pentatricopeptide repeat cassette) gene in cytochrome oxidase assembly: mutation causes lowered levels of COX (cytochrome c oxidase) I and COX III mRNA Biochem. J. 382 2004 331 336
39. V.M. Gohil, R. Nilsson, C.A. Belcher-Timme, B. Luo, D.E. Root, and V.K. Mootha Mitochondrial and nuclear genomic responses to loss of LRPPRC expression J. Biol. Chem. 285 2010 13742 13747
40. N. Sondheimer, J.K. Fang, E. Polyak, M.J. Falk, and N.G. Avadhani Leucine-rich pentatricopeptide-repeat containing protein regulates mitochondrial transcription Biochemistry 49 2010 7467 7473
41. X. Agirrezabala, and J. Frank Elongation in translation as a dynamic interaction among the ribosome, tRNA, and elongation factors EF-G and EF-Tu Q. Rev. Biophys. 42 2009 159 200