Combining quantitative trait loci and heterogeneous microarray data analyses reveals putative candidate pathways affecting mastitis in cattle

Animal Genetics

Volumn 43, Issue 6, 2012, Pages 793-799

  Lewandowska Sabat, A M ^a   Gunther J ^b   Seyfert, H M ^b   Olsaker, I ^a  

^a NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

^b LEIBNIZ INSTITUTE FOR FARM ANIMAL BIOLOGY FBN   (Germany)

Author keywords

cattle; eQTL; macrophages; mastitis; microarray; neutrophiles; QTL

Indexed keywords

INTERLEUKIN 17; INTERLEUKIN 8;

ANIMAL; ARTICLE; BOVINE MASTITIS; CATTLE; CHROMOSOME MAP; DNA MICROARRAY; FEMALE; GENETIC ASSOCIATION; GENETICS; IMMUNOLOGY; MACROPHAGE; METABOLISM; NEUTROPHIL; PATHOLOGY; QUANTITATIVE TRAIT LOCUS; SIGNAL TRANSDUCTION; UDDER;

ANIMALS; CATTLE; CHROMOSOME MAPPING; FEMALE; GENOME-WIDE ASSOCIATION STUDY; INTERLEUKIN-17; INTERLEUKIN-8; MACROPHAGES; MAMMARY GLANDS, ANIMAL; MASTITIS, BOVINE; NEUTROPHILS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; QUANTITATIVE TRAIT LOCI; SIGNAL TRANSDUCTION;

ANIMALIA; BOS;

EID: 84867579661     PISSN: 02689146     EISSN: 13652052     Source Type: Journal    
DOI: 10.1111/j.1365-2052.2012.02342.x     Document Type: Article

References (33)

1. Berasain C., Sampedro A., Mauleón I., et al,. (2009) Epidermal growth factor receptor ligands in murine models for erythropoietic protoporphyria: potential novel players in the progression of liver injury. Cell and Molecular Biology 55, 29-37.
2. Bruno D.R., Rossitto P.V., Bruno R.G., Blanchard M.T., Sitt T., Yeargan B.V., Smith W.L., Cullor J.S., &, Stott J.L., (2010) Differential levels of mRNA transcripts encoding immunologic mediators in mammary gland secretions from dairy cows with subclinical environmental Streptococci infections. Veterinary Immunology and Immunopathology 138, 15-24.
3. Burvenich C., Paape M.J., Hill A.W., Guidry A.J., Miller R.H., Heyneman R., Kremer W.D., &, Brand A., (1994) Role of the neutrophil leucocyte in the local and systemic reactions during experimentally induced E. coli mastitis in cows immediately after calving. The Veterinary Quarterly 16, 45-50.
4. Chang B.S., Bohach G.A., Lee S.U., Davis W.C., Fox L.K., Ferens W.A., Seo K.S., Koo H.C., Kwon N.H., &, Park Y.H., (2005) Immunosuppression by T regulatory cells in cows infected with Staphylococcal superantigen. Journal of Veterinary Science 6, 247-250. (Pubitemid 41354995)
5. Dennis G. Jr, Sherman B.T., Hosack D.A., Yang J., Gao W., Lane H.C., &, Lempicki R.A., (2003) david: database for annotation, visualization, and integrated discovery. Genome Biology 4, P3.
6. Genetos D.C., Rao R.R., &, Vidal M.A., (2010) Betacellulin inhibits osteogenic differentiation and stimulates proliferation through HIF-1alpha. Cell Tissue Research 340, 81-89.
7. Genini S., Badaoui B., Sclep G., et al,. (2011) Strengthening insights into host responses to mastitis infection in ruminants by combining heterogeneous microarray data sources. BMC Genomics 12, 225. Doi: 10.1186/1471-2164-12-225.
8. Günther J., Koczan D., Yang W., Nürnberg G., Repsilber D., Schuberth H.J., Park Z., Maqbool N., Molenaar A., &, Seyfert H.M., (2009) Assessment of the immune capacity of mammary epithelial cells: comparison with mammary tissue after challenge with Escherichia coli. Veterinary Research 40, 31.
9. Günther J., Esch K., Poschadel N., Petzl W., Zerbe H., Mitterhuemer S., Blum H., &, Seyfert H.M., (2011) Comparative kinetics of Escherichia coli- and Staphylococcus aureus-specific activation of key immune pathways in mammary epithelial cells demonstrates that S. aureus elicits a delayed response dominated by interleukin-6 (IL-6) but not by IL-1A or tumor necrosis factor alpha. Infection and Immunity 79, 695-707.
10. Heinrich P.C., Behrmann I., Haan S., Hermanns H.M., Müller-Newen G., &, Schaper F., (2003) Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochemical Journal 374, 1-20. (Pubitemid 37046923)
11. Huang da W., Sherman B.T., Tan Q., et al,. (2007) david bioinformatics resources: expanded annotation database and novel algorithms to better extract biology from large gene lists. Nucleic Acids Research 35, W169-W175.
12. Kafrouni M.I., Brown G.R., &, Thiele D.L., (2003) The role of TNF-TNFR2 interactions in generation of CTL responses and clearance of hepatic adenovirus infection. Journal of Leukocyte Biology 74, 564-571. (Pubitemid 38040384)
13. Kim E.Y., Priatel J.J., Teh S-J., &, Teh H-S., (2006) TNF receptor type 2 (p75) functions as a costimulator for antigen-driven T cell responses in vivo. Journal of Immunology 176, 1026-1035. (Pubitemid 43099703)
14. Klungland H., Sabry A., Heringstad B., et al,. (2001) Quantitative trait loci affecting clinical mastitis and somatic cell count in dairy cattle. Mammalian Genome 12, 837-42. (Pubitemid 33022282)
15. Kobayashi Y., (2006) Neutrophil infiltration and chemokines. Critical Reviews in Immunology 26, 307-316.
16. Kolls J.K., McCray P.B., &, Chan Y.R., (2008) Cytokine-mediated regulation of antimicrobial proteins. Nature Reviews Immunology 8, 829-835.
17. Koziel J., Maciag-Gudowska A., Mikolajczyk T., Bzowska M., Sturdevant D.E., Whitney A.R., Shaw L.N., DeLeo F.R., &, Potempa J., (2009) Phagocytosis of Staphylococcus aureus by macrophages exerts cytoprotective effects manifested by the upregulation of antiapoptotic factors. PLoS One 4, e5210.
18. Lahouassa H., Rainard P., &, Riollet C., (2008) Identification and characterization of a new interleukin-8 receptor in bovine species. Molecular Immunology 45, 1153-1164. (Pubitemid 350027717)
19. Liu Y., Mei J., Gonzales L., et al,. (2011) IL-17A and TNF-α exert synergistic effects on expression of CXCL5 by Alveolar Type II cells in vivo and in vitro. Journal of Immunology 186, 3197-3205.
20. Lutzow Y.C., Donaldson L., Gray C.P., Vuocolo T., Pearson R.D., Reverter A., Byrne K.A., Sheehy P.A., Windon R., &, Tellam R.L., (2008) Identification of immune genes and proteins involved in the response of bovine mammary tissue to Staphylococcus aureus infection. BMC Veterinary Research 4, 18.
21. Marsden V.S., &, Strasser A., (2003) Control of apoptosis in the immune system: Bcl-2, BH3-only proteins and more. Annual Review of Immunology 21, 71-105. (Pubitemid 37174527)
22. Moyes K.M., Drackley J.K., Morin D.E., Bionaz M., Rodriguez-Zas S.L., Everts R.E., Lewin H.A., &, Loor J.J., (2009) Gene network and pathway analysis of bovine mammary tissue challenged with Streptococcus uberis reveals induction of cell proliferation and inhibition of PPARgamma signaling as potential mechanism for the negative relationships between immune response and lipid metabolism. BMC Genomics 10, 542.
23. Murray P.J., (2006) Understanding and exploiting the endogenous interleukin-10/STAT3-mediated anti-inflammatory response. Current Opinion in Pharmacology 6, 379-386.
24. Ogorevc J., Kunej T., Razpet A., &, Dovc P., (2009) Database of cattle candidate genes and genetic markers for milk production and mastitis. Animal Genetics 40, 832-851.
25. Osteras O., Kruse H., Sølverød L., Gjestvang J., &, Mørk T., (2006) Nordic view concerning mastitis pathogens resistance. Proceedings NMC 45th Annual Meeting. Tampa, Florida.
26. Ramadori G., &, Christ B., (1999) Cytokines and the hepatic acute-phase response. Seminars in Liver Disease 19, 141-155.
27. Sodeland M., Kent M.P., Olsen H.G., Opsal M.A., Svendsen M., Sehested E., Hayes B.J., &, Lien S., (2011) Quantitative trait loci for clinical mastitis on chromosomes 2, 6, 14 and 20 in Norwegian Red cattle. Animal Genetics 42, 457-465.
28. Suojala L., Orro T., Jarvinen H., Saatsi J., &, Pyorala S., (2008) Acute phase response in two consecutive experimentally induced E. coli intramammary infections in dairy cows. Acta Veterinaria Scandinavica 50, 18.
29. Tao W., &, Mallard B., (2007) Differentially expressed genes associated with Staphylococcus aureus mastitis of Canadian Holstein cows. Veterinary Immunology and Immunopathology 120, 201-211. (Pubitemid 47632805)
30. Taylor B.C., Dellinger J.D., Cullor J.S., &, Stott J.L., (1994) Bovine milk lymphocytes display the phenotype of memory T cells and are predominantly CD8+. Cell Immunology 156, 245-253. (Pubitemid 24197257)
31. Ulett G.C., &, Adderson E.E., (2006) Regulation of apoptosis by gram-positive bacteria: mechanistic diversity and consequences for immunity. Current Immunology Reviews 2, 119-141. (Pubitemid 44027814)
32. Whelehan C.J., Meade K.G., Eckersall P.D., Young F.J., &, O'Farrelly C., (2011) Experimental Staphylococcus aureus infection of the mammary gland induces region-specific changes in innate immune gene expression. Veterinary Immunology and Immunopathology 140, 181-189.
33. Yasukawa H., Ohishi M., Mori H., et al,. (2003) IL-6 induces an anti-inflammatory response in the absence of SOCS3 in macrophages. Nature Immunology 4, 551-556. (Pubitemid 36701338)