Combined treatment with recombinant tissue plasminogen activator and dexamethasone phosphate-containing liposomes improves neurological outcome and restricts lesion progression after embolic stroke in rats

Journal of Neurochemistry

Volumn 123, Issue SUPPL. 2, 2012, Pages 65-74

  Tiebosch, Ivo A C W ^a   Crielaard, Bart J ^b   Bouts, Mark J R J ^a   Zwartbol, René ^a   Salas Perdomo, Angelica ^c   Lammers, Twan ^b,d,e   Planas, Anna M ^c   Storm, Gert ^b,e   Dijkhuizen, Rick M ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^d RWTH AACHEN UNIVERSITY   (Germany)

^e UNIVERSITY OF TWENTE   (Netherlands)

Author keywords

anti inflammatory treatment; dexamethasone; lipo somes; magnetic resonance imaging; outcome prediction; stroke

Indexed keywords

ALTEPLASE; BIOLOGICAL MARKER; DEXAMETHASONE SODIUM PHOSPHATE; LIPOSOME;

ACUTE DISEASE; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; BLOOD CLOT; BODY WEIGHT; BRAIN DAMAGE; BRAIN INFARCTION SIZE; BRAIN PERFUSION; CONFERENCE PAPER; CONTINUOUS INFUSION; CONTROLLED STUDY; DISEASE COURSE; DOSE RESPONSE; DRUG EFFICACY; LIPOSOMAL DELIVERY; MALE; MENTAL HEALTH; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROIMAGING; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OCCLUSIVE CEREBROVASCULAR DISEASE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RAT; REAL TIME POLYMERASE CHAIN REACTION;

ANALYSIS OF VARIANCE; ANIMALS; ANTIGENS, CD11B; BODY WEIGHT; BRAIN; CYTOKINES; DEXAMETHASONE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; EMBOLISM; FIBRINOLYTIC AGENTS; FUNCTIONAL LATERALITY; GENE EXPRESSION REGULATION; IMAGE PROCESSING, COMPUTER-ASSISTED; LIPOSOMES; MAGNETIC RESONANCE IMAGING; MALE; MATRIX METALLOPROTEINASE 2; NERVOUS SYSTEM DISEASES; NITRIC OXIDE SYNTHASE TYPE II; RATS; RATS, WISTAR; STROKE; TISSUE PLASMINOGEN ACTIVATOR;

EID: 84867562059     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07945.x     Document Type: Conference Paper

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