The role of melanin-concentrating hormone in conditioned reward learning

European Journal of Neuroscience

Volumn 36, Issue 8, 2012, Pages 3126-3133

  Sherwood, Andrew ^a   Wosiski Kuhn, Marlena ^a   Nguyen, Truc ^a   Holland, Peter C ^a   Lakaye, Bernard ^b   Adamantidis, Antoine ^c   Johnson, Alexander W ^a  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b UNIVERSITY OF LIÈGE   (Belgium)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

Antagonist; Conditioned reinforcement; MCH 1R; Mice; Pavlovian instrumental transfer

Indexed keywords

MELANIN CONCENTRATING HORMONE RECEPTOR 1; MELANIN CONCENTRATING HORMONE RECEPTOR 1 ANTAGONIST;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ARTICLE; ASSOCIATION; CONDITIONING; CONTROLLED STUDY; GENE DELETION; GENE DISRUPTION; LEARNING; LIMBIC SYSTEM; MALE; MOTIVATION; MOUSE; NONHUMAN; PERFORMANCE; PRIORITY JOURNAL; REINFORCEMENT; REWARD; VENTRAL TEGMENTUM;

ANIMALS; CONDITIONING, CLASSICAL; GENE DELETION; LEARNING; MICE; MICE, INBRED C57BL; MICE, MUTANT STRAINS; OLIGOPEPTIDES; RECEPTORS, PITUITARY HORMONE; REWARD;

EID: 84867557518     PISSN: 0953816X     EISSN: 14609568     Source Type: Journal    
DOI: 10.1111/j.1460-9568.2012.08207.x     Document Type: Article

References (37)

1. Adamantidis, A., Thomas, E., Foidart, A., Tyhon, A., Coumans, B., Minet, A., Tirelli, E., Seutin, V., Grisar, T. & Lakaye, B. (2005) Disrupting the melanin-concentrating hormone receptor 1 in mice leads to cognitive deficits and alterations of NMDA receptor function. Eur. J. Neurosci., 21, 2837-2844.
2. Bednarek, M.A., Hreniuk, D.L., Tan, C., Palyha, O.C., MacNeil, D.J., Van der Ploeg, L.H.Y., Howard, A.D. & Feighner, S.D. (2002) Synthesis and biological evaluation in vitro of selective, high affinity peptide antagonists of human melanin-concentrating hormone action at human melanin-concentrating hormone receptor 1. Biochemistry, 41, 6383-6390.
3. Berridge, K.C., Ho, C.Y., Richard, J.M. & DiFeliceantonio, A.G. (2010) The tempted brain eats: pleasure and desire circuits in obesity and eating disorders. Brain Res., 1350, 43-64.
4. Berthoud, H.R., Lenard, N.R. & Shin, A.C. (2011) Food reward, hyperphagia, and obesity. Am. J. Physiol. Regul. Integr. Comp. Physiol., 300, R1266-R1277.
5. Bittencourt, J.C., Presse, F., Arias, C., Peto, C., Vaughan, J., Nahon, J.L., Vale, W. & Sawchenko, P.E. (1992) The melanin-concentrating hormone system of the rat brain: an immuno- and hybridization histochemical characterization. J Comp Neurol, 319, 218-245.
6. Burns, L.H., Robbins, T.W. & Everitt, B.J. (1993) Differential effects of excitotoxic lesions of the basolateral amygdala, ventral subiculum and medial prefrontal cortex on responding with conditioned reinforcement and locomotor activity potentiated by intra-accumbens infusions of D-amphetamine. Behav. Brain Res., 55, 167-183.
7. Cador, M., Robbins, T.W. & Everitt, B.J. (1989) Involvement of the amygdala in stimulus reward associations - interaction with the ventral striatum. Neuroscience, 30, 77-86.
8. Chen, Y., Hu, C., Hsu, C.K., Zhang, Q., BI, C., Asnicar, M. & Hansen, M. (2002) Targeted disruption of the melanin-concentrating hormone receptor-1 results in hyperphagia and resistance to diet-induced obesity. Endocrinology, 143, 2469-2477.
9. Chung, S.J., Saito, Y. & Civelli, O. (2009a) MCH receptors/gene structure-in vivo expression. Peptides, 30, 1985-1989.
10. Chung, S.J., Hopf, F.W., Nagasaki, H., Li, C.Y., Belluzzi, J.D., Bonci, A. & Civelli, O. (2009b) The melanin-concentrating hormone system modulates cocaine reward. Proc. Natl. Acad. Sci. USA, 106, 6772-6777.
11. Crombag, H.S., Johnson, A.W., Zimmer, A.M., Zimmer, A. & Holland, P.C. (2010) Deficits in sensory-specific devaluation task performance following genetic deletions of cannabinoid (CB1) receptor. Learn. Mem., 17, 18-22.
12. Della-Zuana, O., Presse, F., Ortola, C., Duhault, J., Nahon, J.L. & Levens, N. (2002) Acute and chronic administration of melanin-concentrating hormone enhances food intake and body weight in Wistar and Sprague-Dawley rats. Int. J. Obes. Relat. Metab. Disord., 26, 1289-1295.
13. Duncan, E., Rider, T., Jandacek, R., Clegg, D.J., Benoit, S.C., Tso, P. & Woods, S.C. (2006) The regulation of alcohol intake by melanin-concentrating hormone in rats. Pharmacol. Biochem. Behav., 85, 728-735.
14. Georgescu, D., Sears, R.M., Hommel, J.D., Barrot, M., Bolanos, C.A., Marsh, D.J., Bednarek, M.A., Bibb, J.A., Maratos-Flier, E., Nestler, E.J. & DiLeone, R.J. (2005) The hypothalamic neuropeptide melanin-concentrating hormone acts in the nucleus accumbens to modulate feeding behavior and forced-swim performance. J. Neurosci., 25, 2933-2940.
15. Gomori, A., Ishihara, A., Ito, M., Mashiko, S., Matsushita, H., Yumoto, M., Ito, M., Tanaka, T., Tokita, S., Moriya, M., Iwaasa, H. & Kanatani, A. (2003) Chronic intracerebroventricular infusion of MCH causes obesity in mice. Am. J. Physiol. Endocrinol. Metab., 284, E583-E588.
16. Guyon, A., Conductier, G., Rovere, C., Enfissi, A. & Nahon, J.L. (2009) Melanin-concentrating hormone producing neurons: activities and modulations. Peptides, 30, 2031-2039.
17. Hervieu, G., Cluderay, J., Harrison, D., Meakin, J., Maycox, P., Nasir, S. & Leslie, R. (2000) The distribution of the mRNA and protein products of the melanin-concentrating hormone (MCH) receptor gene, slc-1, in the central nervous system of the rat. Eur. J. Neurosci., 12, 1194-1216.
18. Hodos, W. (1961) Progressive ratio as a measure of reward strength. Science, 134, 943-944.
19. Holland, P.C. & Gallagher, M. (2003) Double dissociation of the effects of lesions of basolateral and central amygdala on conditioned stimulus-potentiated feeding and Pavlovian-instrumental transfer. Eur. J. Neurosci., 17, 1680-1694.
20. Holland, P.C. & Petrovich, G.D. (2005) A neural systems analysis of the potentiation of feeding by conditioned stimuli. Physiol. Behav., 86, 747-761.
21. Johnson, A.W., Canter, R., Gallagher, M. & Holland, P.C. (2009) Assessing the role of the growth hormone secretagogue receptor in motivational learning and food intake. Behav. Neurosci., 123, 1058-1065.
22. Johnson, A.W., Crombag, H.S., Smith, D.R. & Ramanan, N. (2011) Effects of serum response factor (SRF) deletion on conditioned reinforcement. Behav. Brain Res., 220, 312-318.
23. Kelley, A.E. (2004) Ventral striatal control of appetitive motivation: role in ingestive behavior and reward-related learning. Neurosci. Biobehav. Rev., 27, 765-776.
24. Lex, A. & Hauber, W. (2008) Dopamine D1 and D2 receptors in the nucleus accumbens core and shell mediate Pavlovian-instrumental transfer. Learn. & Mem., 15, 483-491.
25. Ludwig, D.S., Tritos, N.A., Mastaitis, J.W., Kulkarni, R., Kokkotou, E., Elmquist, J., Lowell, B., Flier, J.S. & Maratos-Flier, E. (2001) Melanin-concentrating hormone overexpression in transgenic mice leads to obesity and insulin resistance. J. Clin. Invest., 107, 379-386.
26. Mackintosh, N. 1974. The Psychology of Animal Learning. Academic, London.
27. Marsh, D.J., Weingarth, D.T., Novi, D.E., Chen, H.Y., Trumbauer, M.E., Chen, A.S., Guan, X.M., Jiang, M.M., Feng, Y., Camacho, R.E., Shen, Z., Frazier, E.G., Yu, H., Metzger, J.M., Kuca, S.J., Shearman, L.P., Gopal-Truter, S., MacNeil, D.J., Strack, A.M., MacIntyre, D.E., Van der Ploeg, L.H.T. & Qian, S. (2002) Melanin-concentrating hormone 1 receptor-deficient mice are lean, hyperactive, and hyperphagic and have altered metabolism. Proc. Natl. Acad. Sci. USA, 99, 3240-3245.
28. Mashiko, S., Ishihara, A., Gomori, A., Moriya, R., Ito, M., Iwaasa, H., Matsuda, M., Feng, Y., Shen, Z., Marsh, D.J., Bednarek, M.A., MacNeil, D.J. & Kanatani, A. (2005) Antiobesity effect of a melanin-concentrating hormone 1 receptor antagonist in diet-induced obese mice. Endocrinology, 146, 3080-3086.
29. Mul, J.D., la Fleur, S.E., Toonen, P.W., Afrasiab-Middelman, A., Binnekade, R., Schetters, D. & Verheij, M.M.M. (2011) Chronic loss of melanin-concentrating hormone sffects motivational aspects of feeding in the rat. PLoS ONE, 6, e19600, 1-13.
30. Pears, A., Parkinson, J. & Hopewell, L. (2003) Lesions of the orbitofrontal but not medial prefrontal cortex disrupt conditioned reinforcement in primates. J. Neurosci., 23, 11189-11201.
31. Presse, F., Sorokovsky, I., Max, J.P., Nicolaidis, S. & Nahon, J.L. (1996) Melanin-concentrating hormone is a potent anorectic peptide regulated by food-deprivation and glucopenia in the rat. Neuroscience, 71, 735-745.
32. Qu, D.Q., Ludwig, D.S., Gammeltoft, S., Piper, M., Pelleymounter, M.A., Cullen, M.J., Mathes, W.F., Przypek, J., Kanarek, R. & MaratosFlier, E. (1996) A role for melanin-concentrating hormone in the central regulation of feeding behaviour. Nature, 380, 243-247.
33. Rescorla, R.A. & Solomon, R.L. (1967) 2-Process learning theory - relationships between pavlovian conditioning and instrumental learning. Psych Rev, 74, 151.
34. Sears, R.M., Liu, R.-J., Narayanan, N.S., Sharf, R., Yeckel, M.F., Laubach, M., Aghajanian, G.K. & DiLeone, R.J. (2010) Regulation of nucleus accumbens activity by the hypothalamic neuropeptide melanin-concentrating hormone. J. Neurosci., 30, 8263-8273.
35. Shimada, M., Tritos, N.A., Lowell, B.B., Flier, J.S. & Maratos-Flier, E. (1998) Mice lacking melanin-concentrating hormone are hypophagic and lean. Nature, 396, 670-674.
36. Tan, C.P., Sano, H., Iwaasa, H., Pan, J., Sailer, A.W., Hreniuk, D.L., Feighner, S.D., Palyha, O.C., Pong, S.S., Figueroa, D.J., Austin, C.P., Jiang, M.M., Yu, H., Ito, J., Ito, M., Ito, M., Guan, X.M., MacNeil, D.J., Kanatani, A., Van der Ploeg, L.H. & Howard, A.D. (2002) Melanin-concentrating hormone receptor subtypes 1 and 2: species-specific gene expression. Genomics, 79, 785-792.
37. Taylor, J.R. & Robbins, T.W. (1986) 6-Hydroxydopamine lesions of the nucleus accumbens, but not of the caudate nucleus, attenuate enhanced responding with reward-related stimuli produced by intra-accumbens d-amphetamine. Psychopharmacology, 90, 390-397.