Fas, fas ligand, and vitamin D receptor FokI gene polymorphisms in patients with type 1 diabetes mellitus in the Aegean region of Turkey

Genetic Testing and Molecular Biomarkers

Volumn 16, Issue 10, 2012, Pages 1179-1183

  Sahin, Serap Baydur ^a   Cetinkalp, Sevki ^a   Erdogan, Mehmet ^a   Yilmaz, Candeger ^a   Berdeli, Afig ^a  

^a EGE UNIVERSITY SCHOOL OF MEDICINE   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; CYSTEINE; FAS ANTIGEN; FAS LIGAND; FOK1 PROTEIN; GLYCINE; THREONINE; UNCLASSIFIED DRUG; VITAMIN D RECEPTOR;

ADULT; ALLELE; ARTICLE; CONTROLLED STUDY; DIABETIC PATIENT; DIAGNOSTIC TEST ACCURACY STUDY; DISEASE PREDISPOSITION; FEMALE; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HISTOPATHOLOGY; HUMAN; INSULIN DEPENDENT DIABETES MELLITUS; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PROTEIN LOCALIZATION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SENSITIVITY AND SPECIFICITY; SINGLE NUCLEOTIDE POLYMORPHISM; TURKEY (REPUBLIC);

ADULT; ANTIGENS, CD95; ASIAN CONTINENTAL ANCESTRY GROUP; DEOXYRIBONUCLEASES, TYPE II SITE-SPECIFIC; DIABETES MELLITUS, TYPE 1; FAS LIGAND PROTEIN; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC; RECEPTORS, CALCITRIOL; TURKEY;

EID: 84867534040     PISSN: 19450265     EISSN: 19450257     Source Type: Journal    
DOI: 10.1089/gtmb.2012.0173     Document Type: Article

References (25)

1. Ban Y, Taniyama M, Yanagawa T, et al. (2001) Vitamin D receptor initiation codon polymorphism influences genetic susceptibility to type 1 diabetes mellitus in the Japanese population. BMC Med Genet 2:7.
2. Cetinkalp S, Delen Y, Karadeniz M, et al. (2009) The effect of 1alpha, 25(OH)2D3 vitamin over oxidative stress and biochemical parameters in rats where Type 1 diabetes is formed by streptozotocin. J Diabetes Complications 23:401-408.
3. Delaney C, Pavlovic D, Hoorens A, et al. (1997) Cytokines induce deoxyribonucleic acid strand breaks and apoptosis in human pancreatic islet cells. Endocrinology 138:2610-2614.
4. The EURODIAB Substudy 2 Study Group (1999) Vitamin D supplement in early childhood and risk for Type I (insulin-dependent) diabetes mellitus. Diabetologia 42:51-54.
5. Guo SW, Magnuson VL, Schiller JJ, et al. (2006) Meta-analysis of vitamin D receptor polymorphisms and type 1 diabetes: a HuGE review of genetic association studies. Am J Epidemiol 164:711-724.
6. Jahromi MM, Eisenbarth GS (2007) Cellular and molecular pathogenesis of type 1A diabetes. Cell Mol Life Sci 64:865-872.
7. Leithauser F, Dhein J, Mechtersheimer G, et al. (1993) Constitutive and induced expression of APO-1, a new member of the nevre growth fector/tumor necrosis factor receptor superfamily, in normal and neoplastic cells. Lab Invest 69:415-429.
8. Lemos MC, Fagulha A, Coutinho E, et al. (2008) Lack of association of vitamin D receptor gene polymorphisms with susceptibility to type 1 diabetes mellitus in the Portuguese population. Hum Immunol 69:134-138.
9. Luong K, Nguyen LT, Nguyen DN. (2005) The role of vitamin D in protecting type 1 diabetes mellitus. Diabetes Metab Res Rev. 21:338-346.
10. Martí G, Audí L, Esteban C, et al. (2004) [Association of vitamin D receptor gene polymorphism with type 1 diabetes mellitus in two Spanish populations]. Med Clin (Barc). 123:286-290.
11. Mohamood AS, Guler ML, Xiao Z, et al. (2007) Protection from autoimmune diabetes and T-cell lymphoproliferation induced by FasL mutation are differentially regulated and can be uncoupled pharmacologically. Am J Pathol 171:97-106.
12. Mory DB, Rocco ER, Miranda WL, et al. (2009) Prevalence of vitamin D receptor gene polymorphisms FokI and BsmI in Brazilian individuals with type 1 diabetes and their relation to beta-cell autoimmunity and to remaining beta-cell function. Hum Immunol. 70:447-451.
13. Nolsøe RL, Kristiansen OP, Larsen ZM, et al. (2002) Complete mutation scan of the human Fas ligand gene: linkage studies in Type I diabetes mellitus families. Diabetologia 45:134-139.
14. Nolsøe RL, Kristiansen OP, Sangthongpitag K, et al. (2000) Complete molecular scanning of the human Fas gene: muta-tional analysis and linkage studies in families with type I diabetes mellitus. The Danish study group of diabetes in childhood and the Danish IDDM epidemiology and genetics group. Diabetologia 43:800-808.
15. O'Brien B, Harmon B, Cameron D, et al. (1997) Apoptosis is the mode of beta-cell death responsible for the development of IDDM in the nonobese diabetic (NOD) Mouse. Diabetes 46:750-757.
16. Panierakis C, Goulielmos G, Mamoulakis D, et al. (2009) Vitamin D receptor gene polymorphisms and susceptibility to type 1 diabetes in Crete, Greece. Clin Immunol 133:276-281.
17. Pirot P, Cardozo AK, Eizirik DL (2008) Mediators and mechanisms of pancreatic beta-cell death in type 1 diabetes. Arq Bras Endocrinol Metabol 52:156-165.
18. Shuai K (1994) Interferon-activated signal transduction to the nucleus. Curr Opin Cell Biol 6:253-259.
19. Signore A, Annovazzi A, Gradini R, et al. (1998) Fas and Fas ligand-mediated apoptosis and its role in autoimmune diabetes. Diabetes Metab Rev 14:197-206.
20. Stuck BJ, Pani MA, Besrour F, et al. (2003) Fas ligand gene polymorphisms are not associated with Hashimoto's thy-roiditis and Graves' disease. Human Immunol 64:285-289.
21. Turpeinen H, Hermann R, Vaara S, et al. (2003) Vitamin D receptor polymorphisms: no association with type 1 diabetes in the Finnish population. Eur J Endocrinol 149:591-596.
22. Wu J, Wilson J, He J, et al. (1996) Fas ligand mutation in a patient with systemic lupus eritematosus and lymphoproliferative disease. J Clin Invest 98:1107-1113.
23. Yokota I, Satomura S, Kitamura S, et al. (2002) Association between vitamin D receptor genotype and age of onset in juvenile Japanese patients with type 1 diabetes. Diabetes Care 25:1244.
24. Zella JB, McCary LC, DeLuca HF (2003) Oral administration of 1, 25-dihydroxyvitamin D3 completely protects NOD mice from insulin-dependent diabetes mellitus. Arch Biochem Bio-phys 417:77-80.
25. Zemunik T, Skrabic V, Boraska V, et al. (2005) FokI polymorphism, vitamin D receptor, and interleukin-1 receptor haplo-types are associated with type 1 diabetes in the Dalmatian population. J Mol Diagn 7:600-604.