Pharmacokinetics of protocatechuic acid in mouse and its quantification in human plasma using LC-tandem mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 908, Issue , 2012, Pages 39-44

  Chen, Wei ^a,b   Wang, Dian ^c   Wang, Li shu ^c   Bei, Di ^b   Wang, Jiang ^d   See, William A ^c   Mallery, Susan R ^b   Stoner, Gary D ^c   Liu, Zhongfa ^b,d  

^a ZHEJIANG CANCER HOSPITAL   (China)

^b OHIO STATE UNIVERSITY   (United States)

^c MEDICAL COLLEGE OF WISCONSIN   (United States)

^d OHIO STATE UNIVERSITY   (United States)

Author keywords

LC MS MS; Pharmacokinetics; Plasma; Protocatechuic acid

Indexed keywords

ANALYTICAL TOOL; CLINICAL STUDY; COEFFICIENT OF VARIATION; CONCENTRATION-TIME; HUMAN PLASMAS; IN-VITRO; LC-MS/MS; LOWER LIMIT OF QUANTIFICATIONS; ORAL ADMINISTRATION; ORAL INGESTION; PLASMA LEVELS; PRE-CLINICAL; PROSTATE CANCERS; PROTOCATECHUIC ACID;

ANTHOCYANINS; MAMMALS; MASS SPECTROMETRY; PHARMACOKINETICS; PLASMA (HUMAN); PLASMAS;

DATA HANDLING;

PROTOCATECHUIC ACID;

ACCURACY; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DRUG ABSORPTION; DRUG HALF LIFE; DRUG METABOLISM; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROSTATE CANCER; QUALITY CONTROL; TANDEM MASS SPECTROMETRY;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DRUG STABILITY; FEMALE; FRUIT; HUMANS; HYDROXYBENZOATES; MALE; MICE; PROSTATIC NEOPLASMS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

MUS; RUBUS OCCIDENTALIS;

EID: 84867456967     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2012.09.032     Document Type: Article

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