Methyljasmonate displays in vitro and in vivo activity against multiple myeloma cells

British Journal of Haematology

Volumn 159, Issue 3, 2012, Pages 340-351

  Klippel, Steffen ^a   Jakubikova, Jana ^a   Delmore, Jake ^a   Ooi, Melissa ^a   Mcmillin, Douglas ^a   Kastritis, Efstathios ^a   Laubach, Jacob ^a   Richardson, Paul G ^a   Anderson, Kenneth C ^a   Mitsiades, Constantine S ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Aldo keto reductases; ATP depletion; Jasmonates; Metabolic activity; Multiple myeloma

Indexed keywords

ADENOSINE TRIPHOSPHATE; ALDOKETO REDUCTASE FAMILY 1 MEMBER C1; BORTEZOMIB; CELL ENZYME; DEOXYGLUCOSE; DEXAMETHASONE; DOXORUBICIN; GLUCOSE; HEXOKINASE; HEXOKINASE 2; JASMONIC ACID METHYL ESTER; LACTIC ACID; LENALIDOMIDE; RAPAMYCIN; UNCLASSIFIED DRUG; VOLTAGE DEPENDENT ANION CHANNEL 2; VOLTAGE DEPENDENT ANION CHANNEL 3;

AMINO ACID SYNTHESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL CULTURE; CANCER SURVIVAL; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DISEASE MARKER; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG POTENTIATION; DRUG RESPONSE; ENZYME LOCALIZATION; GLUCOSE INTAKE; HUMAN; HUMAN CELL; HUMAN TISSUE; IC 50; IN VITRO STUDY; IN VIVO STUDY; INTRACELLULAR SIGNALING; MITOCHONDRION; MOLECULAR DYNAMICS; MOUSE; MULTIPLE MYELOMA; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROGRESSION FREE SURVIVAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SENSITIVITY ANALYSIS;

ACETATES; ADENOSINE TRIPHOSPHATE; ANIMALS; ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL SURVIVAL; CYCLOPENTANES; DRUG SYNERGISM; HUMANS; LEUKOCYTES, MONONUCLEAR; MICE; MICE, INBRED NOD; MICE, SCID; MITOCHONDRIA; MULTIPLE MYELOMA; OXYLIPINS; PLANT GROWTH REGULATORS;

EID: 84867447062     PISSN: 00071048     EISSN: 13652141     Source Type: Journal    
DOI: 10.1111/j.1365-2141.2012.09253.x     Document Type: Article

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