Putative Calcium Channels CchA and MidA Play the Important Roles in Conidiation, Hyphal Polarity and Cell Wall Components in Aspergillus nidulans

PLoS ONE

Volumn 7, Issue 10, 2012, Pages

  Wang, Sha ^a   Cao, Jinling ^a   Liu, Xiao ^a   Hu, Hongqin ^a   Shi, Jie ^a   Zhang, Shizhu ^a   Keller, Nancy P ^b   Lu, Ling ^a  

^a NANJING NORMAL UNIVERSITY   (China)

^b UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM CHANNEL; CALCIUM CHANNEL CCHA; CALCIUM CHANNEL MIDA; UNCLASSIFIED DRUG;

ARTICLE; ASPERGILLUS NIDULANS; BINDING AFFINITY; CALCIUM BINDING; CELL COMPONENT; CELL DENSITY; CELL WALL; CONIDIUM; CONTROLLED STUDY; FUNGAL SPORE GERMINATION; FUNGAL VIABILITY; FUNGUS GROWTH; FUNGUS HYPHAE; FUNGUS HYPHAE POLARITY; GENE DELETION; INOCULATION; METULAE; NONHUMAN; NUCLEOTIDE SEQUENCE; NULL ALLELE; OSMOTIC STRESS; PHENOTYPE; PHIALIDE; PHYLOGENY;

ASPERGILLUS NIDULANS; BENZENESULFONATES; CALCINEURIN; CALCIUM; CALCIUM CHANNELS; CELL POLARITY; CELL WALL; CHITIN; CONGO RED; FUNGAL PROTEINS; GENE KNOCKOUT TECHNIQUES; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; HYPHAE; PHENOTYPE; PHYLOGENY; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN STRUCTURE, TERTIARY; SEQUENCE ANALYSIS, PROTEIN; SPORES, FUNGAL;

EID: 84867426212     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0046564     Document Type: Article

References (61)

1. Ambudkar IS, (2011) Dissection of calcium signaling events in exocrine secretion. Neurochem Res 36: 1212-1221.
2. Patergnani S, Suski JM, Agnoletto C, Bononi A, Bonora M, et al. (2011) Calcium signaling around Mitochondria Associated Membranes (MAMs). Cell Commun Signal 9: 19.
3. Stiber JA, Rosenberg PB, (2011) The role of store-operated calcium influx in skeletal muscle signaling. Cell Calcium 49: 341-349.
4. Brand A, Lee K, Veses V, Gow NAR, (2009) Calcium homeostasis is required for contact-dependent helical and sinusoidal tip growth in Candida albicans hyphae. Molecular Microbiology 71: 1155-1164.
5. Gao L, Song Y, Cao J, Wang S, Wei H, et al. (2011) Osmotic stabilizer-coupled suppression of NDR defects is dependent on the calcium-calcineurin signaling cascade in Aspergillus nidulans. Cell Signal 23: 1750-1757.
6. Ma Y, Sugiura R, Koike A, Ebina H, Sio SO, et al. (2011) Transient receptor potential (TRP) and Cch1-Yam8 channels play key roles in the regulation of cytoplasmic Ca2+ in fission yeast. PLoS One 6: e22421.
7. Cunningham KW, (2011) Acidic calcium stores of Saccharomyces cerevisiae. Cell Calcium 50: 129-138.
8. Martin DC, Kim H, Mackin NA, Maldonado-Baez L, Evangelista CC, et al. (2011) New Regulators of a High Affinity Ca2+ Influx System Revealed through a Genome-wide Screen in Yeast. Journal of Biological Chemistry 286: 10744-10754.
9. Groppi S, Belotti F, Brandao RL, Martegani E, Tisi R, (2011) Glucose-induced calcium influx in budding yeast involves a novel calcium transport system and can activate calcineurin. Cell Calcium 49: 376-386.
10. Paidhungat M, Garrett S, (1997) A homolog of mammalian, voltage-gated calcium channels mediates yeast pheromone-stimulated Ca2+ uptake and exacerbates the cdc1 (Ts) growth defect. Molecular and cellular biology 17: 6339-6347.
11. Wolfe DM, Pearce DA, (2006) Channeling studies in yeast: yeast as a model for channelopathies? Neuromolecular Med 8: 279-306.
12. Tasaka Y, Nakagawa Y, Sato C, Mino M, Uozumi N, et al. (2000) yam8(+), a Schizosaccharomyces pombe gene, is a potential homologue of the Saccharomyces cerevisiae MID1 gene encoding a stretch-activated Ca2+-permeable channel. Biochemical and Biophysical Research Communications 269: 265-269.
13. Lew RR, Abbas Z, Anderca MI, Free SJ, (2008) Phenotype of a mechanosensitive channel mutant, mid-1, in a filamentous fungus, Neurospora crassa. Eukaryotic Cell 7: 647-655.
14. Liu M, Du P, Heinrich G, Cox GM, Gelli A, (2006) Cch1 mediates calcium entry in Cryptococcus neoformans and is essential in low-calcium environments. Eukaryotic Cell 5: 1788-1796.
15. Cavinder B, Hamam A, Lew RR, Trail F, (2011) Mid1, a Mechanosensitive Calcium Ion Channel, Affects Growth, Development, and Ascospore Discharge in the Filamentous Fungus Gibberella zeae. Eukaryotic Cell 10: 832-841.
16. Hallen HE, Trail F, (2008) The L-type calcium ion channel cch1 affects ascospore discharge and mycelial growth in the filamentous fungus Gibberella zeae (anamorph Fusarium graminearum). Eukaryot Cell 7: 415-424.
17. Bormann J, Tudzynski P, (2009) Deletion of Mid1, a putative stretch-activated calcium channel in Claviceps purpurea, affects vegetative growth, cell wall synthesis and virulence. Microbiology-Sgm 155: 3922-3933.
18. Zhou XL, Stumpf MA, Hoch HC, Kung C, (1991) A mechanosensitive channel in whole cells and in membrane patches of the fungus Uromyces. Science 253: 1415-1417.
19. Tada T, Ohmori M, Iida H, (2003) Molecular dissection of the hydrophobic segments H3 and H4 of the yeast Ca2+ channel component Mid1. Journal of Biological Chemistry 278: 9647-9654.
20. Teng JF, Goto R, Iida K, Kojima I, Iida H, (2008) Ion-channel blocker sensitivity of voltage-gated calcium-channel homologue Cch1 in Saccharomyces cerevisiae. Microbiology-Sgm 154: 3775-3781.
21. Kmetzsch L, Staats CC, Rodrigues ML, Schrank A, Vainstein MH, (2011) Calcium signaling components in the human pathogen: Cryptococcus neoformans. Communicative & Integrative Biology 4: 186.
22. Denning DW, Perlin DS, (2011) Azole resistance in Aspergillus: a growing public health menace. Future Microbiol 6: 1229-1232.
23. Adams TH, Wieser JK, Yu JH, (1998) Asexual sporulation in Aspergillus nidulans. Microbiology and Molecular Biology Reviews 62: 35-54.
24. Todd RB, Davis MA, Hynes MJ, (2007) Genetic manipulation of Aspergillus nidulans: meiotic progeny for genetic analysis and strain construction. Nature Protocols 2: 811-821.
25. Dagenais TR, Chung D, Giles SS, Hull CM, Andes D, et al. (2008) Defects in conidiophore development and conidium-macrophage interactions in a dioxygenase mutant of Aspergillus fumigatus. Infect Immun 76: 3214-3220.
26. Dagenais TR, Keller NP, (2009) Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis. Clin Microbiol Rev 22: 447-465.
27. Dinamarco TM, Freitas FZ, Almeida RS, Brown NA, Dos Reis TF, et al. (2012) Functional Characterization of an Aspergillus fumigatus Calcium Transporter (PmcA) that Is Essential for Fungal Infection. PLoS One 7: e37591.
28. Ni M, Yu JH, (2007) A novel regulator couples sporogenesis and trehalose biogenesis in Aspergillus nidulans. PLoS One 2: e970.
29. Nayak T, Szewczyk E, Oakley CE, Osmani A, Ukil L, et al. (2006) A versatile and efficient gene-targeting system for Aspergillus nidulans. Genetics 172: 1557-1566.
30. Käfer E, (1977) Meiotic and mitotic recombination in Aspergillus and its chromosomal aberrations. Advances in genetics 19: 33-131.
31. Wang JJ, Hu HQ, Wang S, Shi J, Chen SC, et al. (2009) The important role of actinin-like protein (AcnA) in cytokinesis and apical dominance of hyphal cells in Aspergillus nidulans. Microbiology-Sgm 155: 2714-2725.
32. Wang G, Lu L, Zhang CY, Singapuri A, Yuan S, (2006) Calmodulin concentrates at the apex of growing hyphae and localizes to the Spitzenkorper in Aspergillus nidulans. Protoplasma 228: 159-166.
33. Osmani SA, Pu RT, Morris NR, (1988) Mitotic induction and maintenance by overexpression of a G2-specific gene that encodes a potential protein kinase. Cell 53: 237-244.
34. May GS, (1989) The highly divergent beta-tubulins of Aspergillus nidulans are functionally interchangeable. J Cell Biol 109: 2267-2274.
35. Li S, Oakley CE, Chen G, Han X, Oakley BR, et al. (2005) Cytoplasmic dynein's mitotic spindle pole localization requires a functional anaphase-promoting complex, gamma-tubulin, and NUDF/LIS1 in Aspergillus nidulans. Mol Biol Cell 16: 3591-3605.
36. Yu JH, Hamari Z, Han KH, Seo JA, Reyes-Dominguez Y, et al. (2004) Double-joint PCR: a PCR-based molecular tool for gene manipulations in filamentous fungi. Fungal Genetics and Biology 41: 973-981.
37. Shi J, Chen WW, Liu Q, Chen SC, Hu HQ, et al. (2008) Depletion of the MobB and CotA complex in Aspergillus nidulans causes defects in polarity maintenance that can be suppressed by the environment stress. Fungal Genetics and Biology 45: 1570-1581.
38. El-Ganiny AM, Sanders DAR, Kaminskyj SGW, (2008) Aspergillus nidulans UDP-galactopyranose mutase, encoded by ugmA plays key roles in colony growth, hyphal morphogensis, and conidiation. Fungal Genetics and Biology 45: 1533-1542.
39. El-Ganiny AM, Sheoran I, Sanders DAR, Kaminskyj SGW, (2010) Aspergillus nidulans UDP-glucose-4-epimerase UgeA has multiple roles in wall architecture, hyphal morphogenesis, and asexual development. Fungal Genetics and Biology 47: 629-635.
40. Afroz S, El-Ganiny AM, Sanders DAR, Kaminskyj SGW, (2011) Roles of the Aspergillus nidulans UDP-galactofuranose transporter, UgtA in hyphal morphogenesis, cell wall architecture, conidiation, and drug sensitivity. Fungal Genetics and Biology 48: 896-903.
41. Fortwendel JR, Juvvadi PR, Pinchai N, Perfect BZ, Alspaugh JA, et al. (2009) Differential effects of inhibiting chitin and 1, 3-β-d-glucan synthesis in Ras and calcineurin mutants of Aspergillus fumigatus. Antimicrobial Agents and Chemotherapy 53: 476-482.
42. Lehmann PF, White L, (1975) Chitin assay used to demonstrate renal localization and cortisone-enhanced growth of Aspergillus fumigatus mycelium in mice. Infection and immunity 12: 987-992.
43. Fujikawa T, Kuga Y, Yano S, Yoshimi A, Tachiki T, et al. (2009) Dynamics of cell wall components of Magnaporthe grisea during infectious structure development. Molecular Microbiology 73: 553-570.
44. Zhang S, Xia Y, Keyhani NO, (2011) The Bgas1 gene of the entomopathogenic fungus Beauveria bassiana encoding for a putative GPI-anchored β-1, 3-glucanosyltransferase contributes to conidial thermotolerance and virulence. Applied and Environmental Microbiology 77: 2676-2684.
45. Penalva MA, (2005) Tracing the endocytic pathway of Aspergillus nidulans with FM4-64. Fungal Genet Biol 42: 963-975.
46. Harris SD, (2009) The Spitzenkörper: a signalling hub for the control of fungal development? Molecular Microbiology 73: 733-736.
47. Hong MP, Vu K, Bautos J, Gelli A, (2010) Cch1 restores intracellular Ca2+ in fungal cells during endoplasmic reticulum stress. Journal of Biological Chemistry 285: 10951.
48. Klis F, Ram A, Groot P, (2007) A molecular and genomic view of the fungal cell wall. Biology of the fungal cell pp. 97-120.
49. Harris SD, Turner G, Meyer V, Espeso EA, Specht T, et al. (2009) Morphology and development in Aspergillus nidulans: a complex puzzle. Fungal Genetics and Biology 46: S82-S92.
50. Fuchs BB, Mylonakis E, (2009) Our Paths Might Cross: the Role of the Fungal Cell Wall Integrity Pathway in Stress Response and Cross Talk with Other Stress Response Pathways. Eukaryotic Cell 8: 1616-1625.
51. Ouedraogo JP, Hagen S, Spielvogel A, Engelhardt S, Meyer V, (2011) Survival strategies of yeast and filamentous fungi against the antifungal protein AFP. Journal of Biological Chemistry 286: 13859.
52. Yu JH, Mah JH, Seo JA, (2006) Growth and developmental control in the model and pathogenic aspergilli. Eukaryotic Cell 5: 1577-1584.
53. Brown SH, Zarnowski R, Sharpee WC, Keller NP, (2008) Morphological transitions governed by density dependence and lipoxygenase activity in Aspergillus flavus. Applied and Environmental Microbiology 74: 5674-5685.
54. Brown SH, Scott JB, Bhaheetharan J, Sharpee WC, Milde L, et al. (2009) Oxygenase Coordination Is Required for Morphological Transition and the Host-Fungus Interaction of Aspergillus flavus. Molecular Plant-Microbe Interactions 22: 882-894.
55. Herrero-Garcia E, Garzia A, Cordobes S, Espeso EA, Ugalde U, (2011) 8-Carbon oxylipins inhibit germination and growth, and stimulate aerial conidiation in Aspergillus nidulans. Fungal Biol 115: 393-400.
56. Liu J, Farmer JD Jr, Lane WS, Friedman J, Weissman I, et al. (1991) Calcineurin is a common target of cyclophilin-cyclosporin A and FKBP-FK506 complexes. Cell 66: 807-815.
57. Schreiber SL, Crabtree GR, (1992) The mechanism of action of cyclosporin A and FK506. Immunology today 13: 136.
58. Thomson A, Bonham C, Zeevi A, (1995) Mode of action of tacrolimus (FK506): molecular and cellular mechanisms. Therapeutic drug monitoring 17: 584.
59. Ho S, Clipstone N, Timmermann L, Northrop J, Graef I, et al. (1996) The mechanism of action of cyclosporin A and FK506. Clinical immunology and immunopathology 80: S40-S45.
60. Steinbach WJ, Reedy JL, Cramer RA Jr, Perfect JR, Heitman J, (2007) Harnessing calcineurin as a novel anti-infective agent against invasive fungal infections. Nat Rev Microbiol 5: 418-430.
61. Juvvadi PR, Fortwendel JR, Rogg LE, Burns KA, Randell SH, et al. (2011) Localization and activity of the calcineurin catalytic and regulatory subunit complex at the septum is essential for hyphal elongation and proper septation in Aspergillus fumigatus. Mol Microbiol 82: 1235-1259.