메뉴 건너뛰기




Volumn 12, Issue 5, 2012, Pages 375-383

Changes associated with lenalidomide treatment in the gene expression profiles of patients with del(5q)

Author keywords

Del(5q); Gene expression profiling; Lenalidomide; Myelodysplastic syndromes

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; LENALIDOMIDE; TUMOR NECROSIS FACTOR;

EID: 84867418227     PISSN: 21522650     EISSN: 21522669     Source Type: Journal    
DOI: 10.1016/j.clml.2012.04.003     Document Type: Article
Times cited : (12)

References (33)
  • 1
    • 0037097597 scopus 로고    scopus 로고
    • Narrowing and genomic annotation of the commonly deleted region of the 5q- syndrome
    • J. Boultwood, C. Fidler, A.J. Strickson Narrowing and genomic annotation of the commonly deleted region of the 5q- syndrome Blood 99 2002 4638 4641
    • (2002) Blood , vol.99 , pp. 4638-4641
    • Boultwood, J.1    Fidler, C.2    Strickson, A.J.3
  • 2
    • 80053621748 scopus 로고    scopus 로고
    • A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with low-/intermediate-1-risk myelodysplastic syndromes with del5q
    • P. Fenaux, A. Giagounidis, D. Selleslag A randomized phase 3 study of lenalidomide versus placebo in RBC transfusion-dependent patients with low-/intermediate-1-risk myelodysplastic syndromes with del5q Blood 118 2011 3765 3776
    • (2011) Blood , vol.118 , pp. 3765-3776
    • Fenaux, P.1    Giagounidis, A.2    Selleslag, D.3
  • 3
    • 77649303359 scopus 로고    scopus 로고
    • Patients with del(5q) MDS who fail to achieve sustained erythroid or cytogenetic remission after treatment with lenalidomide have an increased risk for clonal evolution and AML progression
    • G. Göhring, A. Giagounidis, G. Büsche Patients with del(5q) MDS who fail to achieve sustained erythroid or cytogenetic remission after treatment with lenalidomide have an increased risk for clonal evolution and AML progression Ann Hematol 89 2010 365 374
    • (2010) Ann Hematol , vol.89 , pp. 365-374
    • Göhring, G.1    Giagounidis, A.2    Büsche, G.3
  • 4
    • 79955607659 scopus 로고    scopus 로고
    • Sudden acute leukemia transformation in a MDS patient with del(5q) in complete cytogenetic remission after lenalidomide
    • M. Breccia, L. Cannella, R. Latagliata Sudden acute leukemia transformation in a MDS patient with del(5q) in complete cytogenetic remission after lenalidomide Leuk Res 35 2011 e69 e70
    • (2011) Leuk Res , vol.35
    • Breccia, M.1    Cannella, L.2    Latagliata, R.3
  • 5
    • 77956516658 scopus 로고    scopus 로고
    • Persistent malignant stem cells in del(5q) myelodysplasia in remission
    • R. Tehranchi, P.S. Woll, K. Anderson Persistent malignant stem cells in del(5q) myelodysplasia in remission N Engl J Med 363 2010 1025 1037
    • (2010) N Engl J Med , vol.363 , pp. 1025-1037
    • Tehranchi, R.1    Woll, P.S.2    Anderson, K.3
  • 6
    • 69949096727 scopus 로고    scopus 로고
    • Mechanism of action of lenalidomide in hematological malignancies
    • V. Kotla, S. Goel, S. Nischal Mechanism of action of lenalidomide in hematological malignancies Hematol Oncol 2 2009 36
    • (2009) Hematol Oncol , vol.2 , pp. 36
    • Kotla, V.1    Goel, S.2    Nischal, S.3
  • 7
    • 77949699420 scopus 로고    scopus 로고
    • Effect of lenalidomide therapy on hematopoiesis of patients with myelodysplastic syndrome associated with chromosome 5q deletion
    • M. Ximeri, A. Galanopoulos, M. Klaus Effect of lenalidomide therapy on hematopoiesis of patients with myelodysplastic syndrome associated with chromosome 5q deletion Haematologica 95 2010 406 414
    • (2010) Haematologica , vol.95 , pp. 406-414
    • Ximeri, M.1    Galanopoulos, A.2    Klaus, M.3
  • 8
    • 0033532557 scopus 로고    scopus 로고
    • Amino-substituted thalidomide analogs: Potent inhibitors of TNF-alpha production
    • G.W. Muller, R. Chen, S.Y. Huang Amino-substituted thalidomide analogs: potent inhibitors of TNF-alpha production Bioorg Med Chem Lett 9 1999 1625 1630
    • (1999) Bioorg Med Chem Lett , vol.9 , pp. 1625-1630
    • Muller, G.W.1    Chen, R.2    Huang, S.Y.3
  • 9
    • 0023277545 scopus 로고
    • Single step Metod of RNA isolation by acid quanidin-isothiocyanate- phenol-chloroform extractionSingle-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • P. Chomczynski, N. Sacchi Single step Metod of RNA isolation by acid quanidin-isothiocyanate-phenol-chloroform extractionSingle-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction Anal Biochem 162 1987 156 159
    • (1987) Anal Biochem , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 11
    • 0035710746 scopus 로고    scopus 로고
    • Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta delta C(T)) method
    • K.J. Livak, T.D. Schmittgen Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta delta C(T)) method Methods 25 2001 402 408
    • (2001) Methods , vol.25 , pp. 402-408
    • Livak, K.J.1    Schmittgen, T.D.2
  • 12
    • 25444513364 scopus 로고    scopus 로고
    • Role of the p38 mitogen-activated protein kinase pathway in cytokine-mediated hematopoietic suppression in myelodysplastic syndromes
    • E. Katsoulidis, Y. Li, P. Yoon Role of the p38 mitogen-activated protein kinase pathway in cytokine-mediated hematopoietic suppression in myelodysplastic syndromes Cancer Res 65 2005 9029 9037
    • (2005) Cancer Res , vol.65 , pp. 9029-9037
    • Katsoulidis, E.1    Li, Y.2    Yoon, P.3
  • 13
    • 77958038475 scopus 로고    scopus 로고
    • NF-κB as a potential therapeutic target in myelodysplastic syndromes and acute myeloid leukemia
    • M. Breccia, G. Alimena NF-κB as a potential therapeutic target in myelodysplastic syndromes and acute myeloid leukemia Expert Opin Ther Targets 14 2010 1157 1176
    • (2010) Expert Opin Ther Targets , vol.14 , pp. 1157-1176
    • Breccia, M.1    Alimena, G.2
  • 14
    • 78549250108 scopus 로고    scopus 로고
    • Recurrent expression signatures of cytokines and chemokines are present and are independently prognostic in acute myelogenous leukemia and myelodysplasia
    • S.M. Kornblau, D. McCue, N. Singh Recurrent expression signatures of cytokines and chemokines are present and are independently prognostic in acute myelogenous leukemia and myelodysplasia Blood 116 2010 4251 4261
    • (2010) Blood , vol.116 , pp. 4251-4261
    • Kornblau, S.M.1    McCue, D.2    Singh, N.3
  • 15
    • 35348834097 scopus 로고    scopus 로고
    • Aberrant cytokine signaling in leukemia
    • R.A. Van Etten Aberrant cytokine signaling in leukemia Oncogene 26 2007 6738 6749
    • (2007) Oncogene , vol.26 , pp. 6738-6749
    • Van Etten, R.A.1
  • 16
    • 77950943405 scopus 로고    scopus 로고
    • Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells
    • A. Pellagatti, M. Cazzola, A. Giagounidis Deregulated gene expression pathways in myelodysplastic syndrome hematopoietic stem cells Leukemia 24 2010 756 764
    • (2010) Leukemia , vol.24 , pp. 756-764
    • Pellagatti, A.1    Cazzola, M.2    Giagounidis, A.3
  • 17
    • 79955739178 scopus 로고    scopus 로고
    • Role of immune responses in the pathogenesis of low-risk MDS and high-risk MDS: Implications for immunotherapy
    • S. Aggarwal, A.A. van de Loosdrecht, C. Alhan Role of immune responses in the pathogenesis of low-risk MDS and high-risk MDS: implications for immunotherapy Br J Haematol 153 2011 568 581
    • (2011) Br J Haematol , vol.153 , pp. 568-581
    • Aggarwal, S.1    Van De Loosdrecht, A.A.2    Alhan, C.3
  • 18
    • 0031464758 scopus 로고    scopus 로고
    • Overexpression of tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma by bone marrow cells from patients with myelodysplastic syndromes
    • M. Kitagawa, I. Saito, T. Kuwata Overexpression of tumor necrosis factor (TNF)-alpha and interferon (IFN)-gamma by bone marrow cells from patients with myelodysplastic syndromes Leukemia 11 1997 2049 2054
    • (1997) Leukemia , vol.11 , pp. 2049-2054
    • Kitagawa, M.1    Saito, I.2    Kuwata, T.3
  • 19
    • 0037411227 scopus 로고    scopus 로고
    • Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes
    • M. Sawanobori, S. Yamaguchi, M. Hasegawa Expression of TNF receptors and related signaling molecules in the bone marrow from patients with myelodysplastic syndromes Leuk Res 27 2003 583 591
    • (2003) Leuk Res , vol.27 , pp. 583-591
    • Sawanobori, M.1    Yamaguchi, S.2    Hasegawa, M.3
  • 20
    • 0028942058 scopus 로고
    • Tumor necrosis factor (TNF)-α directly inhibits human erythropoiesis in vitro: Role of p55 and p75 TNF receptors
    • L.S. Rusten, S.E. Jacobsen Tumor necrosis factor (TNF)-α directly inhibits human erythropoiesis in vitro: role of p55 and p75 TNF receptors Blood 85 1995 989 996
    • (1995) Blood , vol.85 , pp. 989-996
    • Rusten, L.S.1    Jacobsen, S.E.2
  • 21
    • 77950299675 scopus 로고    scopus 로고
    • Hematologically important mutations: The autosomal recessive forms of chronic granulomatous disease (second update)
    • D. Roos, D.B. Kuhns, A. Maddalena Hematologically important mutations: the autosomal recessive forms of chronic granulomatous disease (second update) Blood Cells Mol Dis 44 2010 291 299
    • (2010) Blood Cells Mol Dis , vol.44 , pp. 291-299
    • Roos, D.1    Kuhns, D.B.2    Maddalena, A.3
  • 22
    • 51649097967 scopus 로고    scopus 로고
    • Essential role of nuclear factor-kappaB for NADPH oxidase activity in normal and anhidrotic ectodermal dysplasia leukocytes
    • M. Luengo-Blanco, C. Prando, J. Bustamante Essential role of nuclear factor-kappaB for NADPH oxidase activity in normal and anhidrotic ectodermal dysplasia leukocytes Blood 112 2008 1453 1460
    • (2008) Blood , vol.112 , pp. 1453-1460
    • Luengo-Blanco, M.1    Prando, C.2    Bustamante, J.3
  • 23
    • 69249228563 scopus 로고    scopus 로고
    • A functional heteromeric MIF receptor formed by CD74 and CXCR4
    • V. Schwartz, H. Lue, S. Kraemer A functional heteromeric MIF receptor formed by CD74 and CXCR4 FEBS Lett 583 2009 2749 2757
    • (2009) FEBS Lett , vol.583 , pp. 2749-2757
    • Schwartz, V.1    Lue, H.2    Kraemer, S.3
  • 24
    • 77957788545 scopus 로고    scopus 로고
    • Activation of the JNK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on CXCR4 and CD74
    • H. Lue, M. Dewor, L. Leng Activation of the JNK signalling pathway by macrophage migration inhibitory factor (MIF) and dependence on CXCR4 and CD74 Cell Signal 23 2011 135 144
    • (2011) Cell Signal , vol.23 , pp. 135-144
    • Lue, H.1    Dewor, M.2    Leng, L.3
  • 25
    • 77949732135 scopus 로고    scopus 로고
    • Pathophysiology and treatment of the myelodysplastic syndrome with isolated 5q deletion
    • M. Jädersten Pathophysiology and treatment of the myelodysplastic syndrome with isolated 5q deletion Haematologica 95 2010 348 351
    • (2010) Haematologica , vol.95 , pp. 348-351
    • Jädersten, M.1
  • 26
    • 77955981386 scopus 로고    scopus 로고
    • Role of cartilage-associated protein in skeletal development
    • R. Morello, F. Rauch Role of cartilage-associated protein in skeletal development Curr Osteoporos Rep 8 2010 77 83
    • (2010) Curr Osteoporos Rep , vol.8 , pp. 77-83
    • Morello, R.1    Rauch, F.2
  • 27
    • 54049156803 scopus 로고    scopus 로고
    • Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma
    • I. Breitkreutz, M.S. Raab, S. Vallet Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma Leukemia 22 2008 1925 1932
    • (2008) Leukemia , vol.22 , pp. 1925-1932
    • Breitkreutz, I.1    Raab, M.S.2    Vallet, S.3
  • 28
    • 79953117045 scopus 로고    scopus 로고
    • Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells
    • S. Dutt, A. Narla, K. Lin Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells Blood 117 2011 2567 2576
    • (2011) Blood , vol.117 , pp. 2567-2576
    • Dutt, S.1    Narla, A.2    Lin, K.3
  • 29
    • 84862576157 scopus 로고    scopus 로고
    • Alteration of lipids and the transcription of lipid-related genes in myelodysplastic syndromes via a TP53-related pathway
    • [Epub ahead of print]
    • M.H. Ellis, L. Baraf, A. Shaish Alteration of lipids and the transcription of lipid-related genes in myelodysplastic syndromes via a TP53-related pathway Exp Hematol 2012 Feb 27 [Epub ahead of print]
    • (2012) Exp Hematol
    • Ellis, M.H.1    Baraf, L.2    Shaish, A.3
  • 30
    • 77954701718 scopus 로고    scopus 로고
    • Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A
    • P.R. Molli, D.Q. Li, R. Bagheri-Yarmand Arpc1b, a centrosomal protein, is both an activator and substrate of Aurora A J Cell Biol 190 2010 101 114
    • (2010) J Cell Biol , vol.190 , pp. 101-114
    • Molli, P.R.1    Li, D.Q.2    Bagheri-Yarmand, R.3
  • 31
    • 77954921251 scopus 로고    scopus 로고
    • Cell cycle: ARPC1B - A regulator of regulators
    • M. Skinner Cell cycle: ARPC1B - a regulator of regulators Nat Rev Mol Cell Biol 11 2010 542
    • (2010) Nat Rev Mol Cell Biol , vol.11 , pp. 542
    • Skinner, M.1
  • 32
    • 0141680971 scopus 로고    scopus 로고
    • Oxidative stress and the myelodysplastic syndromes
    • M.J. Farquhar, D.T. Bowen Oxidative stress and the myelodysplastic syndromes Int J Hematol 77 2003 342 350
    • (2003) Int J Hematol , vol.77 , pp. 342-350
    • Farquhar, M.J.1    Bowen, D.T.2
  • 33
    • 42649124339 scopus 로고    scopus 로고
    • TNF: A master switch for inflammation to cancer
    • G. Sethi, B. Sung, B.B. Aggarwal TNF: a master switch for inflammation to cancer Front Biosci 13 2008 5094 5107
    • (2008) Front Biosci , vol.13 , pp. 5094-5107
    • Sethi, G.1    Sung, B.2    Aggarwal, B.B.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.