High glucose increases nitric oxide generation in lipopolysaccharide- activated macrophages by enhancing activity of protein kinase C-α/δ and NF-κB

Inflammation Research

Volumn 61, Issue 10, 2012, Pages 1107-1116

  Hua, Kuo Feng ^a   Wang, Szu Hsuan ^b   Dong, Wei Chih ^a   Lin, Chai Yi ^c   Ho, Chen Lung ^c   Wu, Tzu Hua ^b  

^a NATIONAL ILAN UNIVERSITY   (Taiwan)

^b TAIPEI MEDICAL UNIVERSITY   (Taiwan)

^c TAIWAN FORESTRY RESEARCH INSTITUTE   (Taiwan)

Author keywords

Hyperglycemia; Inflammation; LPS; PKC

Indexed keywords

CYTOKINE; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; MITOGEN ACTIVATED PROTEIN KINASE P38; NITRIC OXIDE; PROTEIN KINASE C ALPHA; PROTEIN KINASE C DELTA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; ASSAY; CELL CULTURE; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE RELEASE; DIABETES MELLITUS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; ENZYME PHOSPHORYLATION; GENETIC TRANSCRIPTION; HYPERGLYCEMIA; INFLAMMATION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REPORTER GENE; WESTERN BLOTTING;

ANIMALS; CELL LINE; CYTOKINES; GLUCOSE; HEK293 CELLS; HUMANS; INFLAMMATION; LIPOPOLYSACCHARIDES; MACROPHAGES; MICE; MITOGEN-ACTIVATED PROTEIN KINASES; NF-KAPPA B; NITRIC OXIDE; NITRIC OXIDE SYNTHASE TYPE II; PROTEIN KINASE C-ALPHA; PROTEIN KINASE C-DELTA;

EID: 84867403251     PISSN: 10233830     EISSN: 1420908X     Source Type: Journal    
DOI: 10.1007/s00011-012-0503-1     Document Type: Article

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