Differential effects of botulinum neurotoxin a on bladder contractile responses to activation of efferent nerves, smooth muscles and afferent nerves in rats

Journal of Urology

Volumn 188, Issue 5, 2012, Pages 1993-1999

  Takahashi, Ryosuke ^a,b   Yunoki, Takakazu ^b   Naito, Seiji ^b   Yoshimura, Naoki ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

botulinum toxins; calcium channels; efferent pathways; muscle contraction; type A; urinary bladder

Indexed keywords

BOTULINUM TOXIN A; CALCIUM CHANNEL L TYPE; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL TISSUE; ARTICLE; BLADDER CONTRACTION; CHANNEL GATING; CONCENTRATION RESPONSE; CONTROLLED STUDY; DETRUSOR MUSCLE; DRUG EFFECT; DRUG MECHANISM; DRUG POTENCY; EFFERENT NERVE; ELECTRIC FIELD; ELECTROSTIMULATION; FEMALE; NERVE ENDING; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; RAT; SENSORY NERVE; SMOOTH MUSCLE CONTRACTION;

AFFERENT PATHWAYS; ANIMALS; BOTULINUM TOXINS, TYPE A; EFFERENT PATHWAYS; FEMALE; MUSCLE CONTRACTION; MUSCLE, SMOOTH; NEUROMUSCULAR AGENTS; RATS; RATS, SPRAGUE-DAWLEY; URINARY BLADDER;

EID: 84867395849     PISSN: 00225347     EISSN: 15273792     Source Type: Journal    
DOI: 10.1016/j.juro.2012.07.001     Document Type: Article

References (24)

1. M. Chancellor, C.J. Fowler, A. Apostolidis Drug insight: biological effects of botulinum toxin A in the lower urinary tract Nat Clin Pract Urol 5 2008 319
2. A. Apostolidis, P. Dasgupta, C.J. Fowler Proposed mechanism for the efficacy of injected botulinum toxin in the treatment of human detrusor overactivity Eur Urol 49 2006 644
3. M.J. Welch, J.R. Purkiss, K.A. Foster Sensitivity of embryonic rat dorsal root ganglia neurons to clostridium botulinum neurotoxins Toxicon 38 2000 245
4. D.E. Rapp, K.W. Turk, G.T. Bales Botulinum toxin type A inhibits calcitonin gene-related peptide release from isolated rat bladder J Urol 175 2006 1138
5. 2+ channels by distinct domains within SNAP-25 Diabetes 51 2002 1425
6. 2+ current in detrusor smooth muscles. Presented at annual meeting of International Continence Society/International Urogynecological Association, Toronto, Ontario, Canada, August 22-27, 2010, program 599.
7. A. De Lean, P.J. Munson, D. Rodbard Simultaneous analysis of families of sigmoidal curves: application to bioassay, radioligand assay, and physiological dose-response curves Am J Physiol 235 1978 E97
8. C. Saitoh, C. Kitada, W. Uchida The differential contractile responses to capsaicin and anandamide in muscle strips isolated from the rat urinary bladder Eur J Pharmacol 570 2007 182
9. S. Howles, J. Curry, I. McKay Lack of effectiveness of botulinum neurotoxin A on isolated detrusor strips and whole bladders from mice and guinea-pigs in vitro BJU Int 104 2009 1524
10. J.L. Mostwin The action potential of guinea pig bladder smooth muscle J Urol 135 1986 1299
11. C.J. McCarthy, I.V. Zabbarova, P.R. Brumovsky Spontaneous contractions evoke afferent nerve firing in mouse bladders with detrusor overactivity J Urol 181 2009 1459
12. A.F. Brading, W.H. Turner The unstable bladder: towards a common mechanism Br J Urol 73 1994 3
13. 2+ channels Br J Pharmacol 163 2011 1276
14. C.A. Maggi, R. Patacchini, P. Santicioli Tachykinin antagonists and capsaicin-induced contraction of the rat isolated urinary bladder: evidence for tachykinin-mediated cotransmission Br J Pharmacol 103 1991 1535
15. N. Yoshimura, M.B. Chancellor Physiology and pharmacology of the bladder and urethra A.J. Wein, L.R. Kavoussi, A.C. Novick, 10th ed. Campbell-Walsh Urology vol 3 2012 Elsevier Saunders Philadelphia 1786 sect XIV, chap 60
16. M. Khera, G.T. Somogyi, S. Kiss Botulinum toxin A inhibits ATP release from bladder urothelium after chronic spinal cord injury Neurochem Int 45 2004 987
17. A. Apostolidis, R. Popat, Y. Yiangou Decreased sensory receptors P2X3 and TRPV1 in suburothelial nerve fibers following intradetrusor injections of botulinum toxin for human detrusor overactivity J Urol 174 2005 977
18. M. Relja, S. Telarovic Botulinum toxin type-A and pain responsiveness in cervical dystonia: a dose response study Mov Disord 20 2005 P77
19. S. Palea, W. Artibani, E. Ostardo Evidence for purinergic neurotransmission in human urinary bladder affected by interstitial cystitis J Urol 150 1993 2007
20. B.A. O'Reilly, A.H. Kosaka, G.F. Knight P2X receptors and their role in female idiopathic detrusor instability J Urol 167 2002 157
21. G.W. Lawrence, K.R. Aoki, J.O. Dolly Excitatory cholinergic and purinergic signaling in bladder are equally susceptible to botulinum neurotoxin A consistent with co-release of transmitters from efferent fibers J Pharmacol Exp Ther 334 2010 1080
22. K. Kishii, T. Hisayama, I. Takayanagi Comparison of contractile mechanisms by carbachol and ATP in detrusor strips of rabbit urinary bladder Japan J Pharmacol 58 1992 219
23. 2+ stores in guinea-pig detrusor smooth muscle J Physiol 583.2 2002 357
24. K.E. Andersson, A. Arner Urinary bladder contraction and relaxation: physiology and pathophysiology Physiol Rev 84 2003 935