Kupffer cell depletion attenuates leptin-mediated methoxamine-stimulated portal perfusion pressure and thromboxane A 2 release in a rodent model of NASH-cirrhosis

Clinical Science

Volumn 123, Issue 12, 2012, Pages 669-680

  Yang, Ying Ying ^a   Huang, Yi Tsau ^b,c   Tsai, Tung Hu ^a,b   Hou, Ming Chih ^a,c   Lee, Fa Yauh ^a,b   Lee, Shou Dong ^a   Lin, Han Chieh ^a  

^a TAIPEI VETERANS GENERAL HOSPITAL   (Taiwan)

^b NATIONAL YANG MING UNIVERSITY   (Taiwan)

^c NATIONAL RESEARCH INSTITUTE OF CHINESE MEDICINE   (Taiwan)

Author keywords

Cirrhosis; Hyperleptinaemia; Methoxamine; Non alcoholic steatohepatitis; Oxidative stress; Polyunsaturated fatty acid

Indexed keywords

7 [3 [(4 PHENYLSEMICARBAZIDO)METHYL] 7 OXABICYCLO[2.2.1]HEPT 2 YL] 5 HEPTENOIC ACID; ARACHIDONIC ACID; BM 567; CLODRONIC ACID; FATTY ACID SYNTHASE; FUREGRELATE; GADOLINIUM CHLORIDE; LEPTIN; MESSENGER RNA; METHOXAMINE; POLYUNSATURATED FATTY ACID; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; THIOBARBITURIC ACID REACTIVE SUBSTANCE; THROMBOXANE A2; THROMBOXANE A2 RECEPTOR BLOCKING AGENT; TRANSFORMING GROWTH FACTOR BETA1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DISEASE ASSOCIATION; HEMODYNAMICS; HYPERLEPTINEMIA; KUPFFER CELL; LIPID COMPOSITION; LIPID DIET; LIVER CIRCULATION; LIVER PERFUSION; NONALCOHOLIC FATTY LIVER; NONHUMAN; OXIDATIVE STRESS; PERFUSION PRESSURE; PORTAL HYPERTENSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

ANALYSIS OF VARIANCE; ANIMALS; ARACHIDONIC ACID; BENZOFURANS; CHOLINE; CLODRONIC ACID; DIET, HIGH-FAT; DNA PRIMERS; FATTY ACIDS, UNSATURATED; FATTY LIVER; GADOLINIUM; HEMODYNAMICS; HYPERTENSION, PORTAL; INSULIN RESISTANCE; KUPFFER CELLS; LEPTIN; METHIONINE; METHOXAMINE; MICROCIRCULATION; OXIDATIVE STRESS; RATS; RECEPTORS, THROMBOXANE A2, PROSTAGLANDIN H2; RNA, MESSENGER; SULFONYLUREA COMPOUNDS; THIOBARBITURIC ACID REACTIVE SUBSTANCES; THROMBOXANE A2;

EID: 84867394147     PISSN: 01435221     EISSN: None     Source Type: Journal    
DOI: 10.1042/CS20110572     Document Type: Article

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