Structural basis for the accommodation of bis- and tris-aromatic derivatives in vitamin D nuclear receptor

Journal of Medicinal Chemistry

Volumn 55, Issue 19, 2012, Pages 8440-8449

  Ciesielski, Fabrice ^a,b   Sato, Yoshiteru ^a,c   Chebaro, Yassmine ^a   Moras, Dino ^a   Dejaegere, Annick ^a   Rochel, Natacha ^a  

^a UNIVERSITÉ DE STRASBOURG   (France)

^b NovAliX   (France)

^c KYUSHU UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD 4528; CD 4720; CD 4742; CD 4802; CD 4849; UNCLASSIFIED DRUG; VITAMIN D DERIVATIVE; VITAMIN D RECEPTOR;

ARTICLE; BINDING AFFINITY; CHEMICAL MODIFICATION; DRUG STRUCTURE;

ANIMALS; BENZENE DERIVATIVES; BIPHENYL COMPOUNDS; CALCITRIOL; CRYSTALLOGRAPHY, X-RAY; HELA CELLS; HUMANS; LIGANDS; MODELS, MOLECULAR; PHENYL ETHERS; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CALCITRIOL; STATIC ELECTRICITY; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTIONAL ACTIVATION; ZEBRAFISH PROTEINS;

EID: 84867372805     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm300858s     Document Type: Article

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