Corneal biomechanical properties from two-dimensional corneal flap extensiometry: Application to UV-Riboflavin cross-linking

Investigative Ophthalmology and Visual Science

Volumn 53, Issue 8, 2012, Pages 5010-5015

  Kling, Sabine ^a,b   Ginis, Harilaos ^b   Marcos, Susana ^a  

^a INSTITUTO DE ÓPTICA   (Spain)

^b UNIVERSITY OF CRETE   (Greece)

Author keywords

[No Author keywords available]

Indexed keywords

RIBOFLAVIN; CROSS LINKING REAGENT;

ABERROMETRY; ANIMAL TISSUE; ARTICLE; ASTIGMATISM; BIOMECHANICS; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CORNEA; CORNEA CURVATURE; CORNEA STROMA; CORNEAL PACHYMETRY; CROSS LINKING; EYE REFRACTION; INTRAOCULAR PRESSURE; MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; RABBIT; SWINE; TWO DIMENSIONAL FLAP EXTENSIOMETRY; ULTRAVIOLET RADIATION; YOUNG MODULUS; ANIMAL; ELASTICITY; PATHOPHYSIOLOGY; RADIATION EXPOSURE;

ANIMALS; BIOMECHANICS; CORNEA; CROSS-LINKING REAGENTS; ELASTICITY; INTRAOCULAR PRESSURE; RABBITS; RIBOFLAVIN; SWINE; ULTRAVIOLET RAYS;

EID: 84867346599     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.12-9583     Document Type: Article

References (24)

1. Wollensak G, Iomdina E. Long-term biomechanical properties of rabbit cornea after photodynamic collagen crosslinking, Acta Ophthalmol. 2009;87;48-51.
2. Wollensak G, Spoerl E, Seiler T. Stress-strain measurements of human and porcine corneas after riboflavin-ultraviolet-A-induced cross-linking. J Cataract Refract Surg. 2003;29: 1780-1785.
3. Elsheikh A, Kassem W, Jones SW. Strain-rate sensitivity of porcine and ovine corneas. Acta Bioeng Biomech. 2011;13: 25-36.
4. Elsheikh A, Anderson K. Comparative study of corneal strip extensometry and inflation tests. J R Soc Interface. 2005;2: 177-185.
5. Boyce BL, Grazier JM, Jones RE, Nguyen TD. Full-field deformation of bovine cornea under constrained inflation conditions. Biomaterials. 2008;29:3896-3904.
6. Knox Cartwright NE, Tyrer JR, Marshall J. Age-related differences in the elasticity of human cornea. Invest Ophthalmol Vis Sci. 2011;52:4324-4329.
7. Jue B, Maurice DM. The mechanical properties of the rabbit and human cornea. J Biomech. 1986;19:847-853.
8. Hjortdal JO. Regional elastic performance of the human cornea. J Biomech. 1996;29:931-942.
9. Litwiller DV, Lee SJ, Kolipaka A, et al. MR elastography of the ex vivo bovine globe. J Magn Reson Imaging. 2010;32: 44-51.
10. Pierscionek BK, Asejczyk-Widlicka M, Schachar RA. The effect of changing IOP on the corneal and sclera curvatures in the fresh porcine eye. Br J Ophthalmol. 2007;91:801-803.
11. Kling S, Remón L, Pérez-Escudero A, Merayo-Lloves J, Marcos S. Corneal biomechanical changes after collagen cross-linking from porcine eye inflation experiments. Invest Ophthalmol Vis Sci. 2010;51:3961-3968.
12. Dorronsoro C, Pascual D, Pérez-Merino P, Kling S, Marcos S. Dynamic OCT measurement of corneal deformation by an air puff in normal and cross-linked corneas. Biomed Opt Exp. 2012;3:473-487.
13. Hamilton KE, Pye DC. Young's modulus in normal corneas and the effect on applanation tonometry. Optom Vis Sci. 2008;85: 445-450.
14. Hjortdal JO. Extensibility of the normo hydrated human cornea. Acta Opthalmol Scand. 1995;73:12-17.
15. Abad JC, Panesso JL. Corneal collagen cross-linking induced by UVA and riboflavin. Techniques in Ophthalmology. 2008; 6:8-12.
16. Wollensak G, Wilsch M, Spoerl E, Seiler T. Collagen fiber diameter in the rabbit cornea after collagen crosslinking by riboflavin/UVA. Cornea. 2004;23:503-507.
17. Guthoff RF, Zhivov A, Stach O. In vivo confocal microscopy, an inner vision of the cornea-a major review. Clin Experiment Ophthalmol. 2009;37:100-117.
18. Kohlhaas M, Spoerl E, Schilde G, Unger G, Wittig C, Pillunat LE. Biomechanical evidence of the distribution of cross-links in corneas treated with riboflavin and ultraviolet A light. J Cataract Refract Surg. 2006;32:279-283.
19. Hjortdal JO, Jensen PK. In vitro measurement of corneal strain, thickness and curvature using digital image processing. Acta Opthalmol Scand. 1995;73:5-11.
20. Wang H, Prendiville PL, McDonnell PJ, Chang WV. An ultrasonic technique for the measurement of the elastic moduli of human cornea. J Biomech. 1996;29:1633-1636.
21. Sedaghat M, Naderi M, Zarei-Ghanavati M. Biomechanical parameters of the cornea after collagen crosslinking measured by waveform analysis. J Cataract Refract Surg. 2010;36:1728-1731.
22. Raiskup-Wolf F, Hoyer A, Spoerl E, Pillunat LE. Collagen crosslinking with riboflavin and ultraviolet-A light in keratoconus: long-term results. J Cataract Refract Surg. 2008;34: 796-801.
23. Hennighausen H, Feldman ST, Bille JF, McCulloch AD. Anterior posterior strain variation in normally hydrated and swollen rabbit cornea. Invest Opthalmol Vis Sci. 1998;39:253-262.
24. Bueno JM, Gualda EJ, Giakoumaki A, Pérez-Merino P, Marcos S, Artal P. Multiphoton microscopy of ex vivo corneas after collagen cross-linking. Invest Opthalmol Vis Sci. 2011;52: 5325-5331.