Interleukin-15 activated bovine natural killer cells express CD69 and produce interferon-γ

Veterinary Immunology and Immunopathology

Volumn 150, Issue 1-2, 2012, Pages 79-89

  Lund, Hege ^a   Boysen, Preben ^a   Dean, Gregg A ^b   Davis, William C ^c   Park, Kun Taek ^c   Storset, Anne K ^a  

^a NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

^b Department of Environmental and Radiological Health Sciences   (United States)

^c WASHINGTON STATE UNIVERSITY   (United States)

Author keywords

Activation; Bovine; CD69; Interferon ; Interleukin 15; Natural killer cells

Indexed keywords

CD69 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 15; INTERLEUKIN 2;

ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; COW; EX VIVO STUDY; IN VITRO STUDY; INTERFERON PRODUCTION; LYMPHOCYTE PROLIFERATION; NATURAL KILLER CELL; NONHUMAN; PROTEIN GLYCOSYLATION; SIGNAL TRANSDUCTION; UPREGULATION;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD; ANTIGENS, DIFFERENTIATION, T-LYMPHOCYTE; CATTLE; FEMALE; FLOW CYTOMETRY; INTERFERON-GAMMA; INTERLEUKIN-15; KILLER CELLS, NATURAL; LECTINS, C-TYPE; LYMPHOCYTE ACTIVATION; MALE; RECOMBINANT PROTEINS;

BOVINAE; MAMMALIA;

EID: 84867334994     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2012.08.011     Document Type: Article

References (38)

1. Ahn J.S., Hamilton M.J., Davis W.C., Park Y.H. Cloning of bovine CD69. Vet. Immunol. Immunopathol. 2002, 88:43-48.
2. Azeredo E.L., Oliveira-Pinto L.M., Zagne S.M., Cerqueira D.I., Nogueira R.M., Kubelka C.F. NK cells, displaying early activation, cytotoxicity and adhesion molecules, are associated with mild dengue disease. Clin. Exp. Immunol. 2006, 143:345-356.
3. Bamford R.N., Battiata A.P., Burton J.D., Sharma H., Waldmann T.A. Interleukin (IL) 15/IL-T production by the adult T-cell leukemia cell line HuT-102 is associated with a human T-cell lymphotrophic virus type I region/IL-15 fusion message that lacks many upstream AUGs that normally attenuates IL-15 mRNA translation. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:2897-2902.
4. Bamford R.N., DeFilippis A.P., Azimi N., Kurys G., Waldmann T.A. The 5' untranslated region, signal peptide, and the coding sequence of the carboxyl terminus of IL-15 participate in its multifaceted translational control. J. Immunol. 1998, 160:4418-4426.
5. Becknell B., Caligiuri M.A. Interleukin-2, interleukin-15, and their roles in human natural killer cells. Adv. Immunol. 2005, 86:209-239.
6. Bergamaschi C., Rosati M., Jalah R., Valentin A., Kulkarni V., Alicea C., Zhang G.M., Patel V., Felber B.K., Pavlakis G.N. Intracellular interaction of interleukin-15 with its receptor alpha during production leads to mutual stabilization and increased bioactivity. J. Biol. Chem. 2008, 283:4189-4199.
7. Boysen P., Eide D.M., Storset A.K. Natural killer cells in free-living Mus musculus have a primed phenotype. Mol. Ecol. 2011, 20:5103-5110.
8. Boysen P., Olsen I., Berg I., Kulberg S., Johansen G.M., Storset A.K. Bovine CD2-/NKp46+ cells are fully functional natural killer cells with a high activation status. BMC Immunol. 2006, 7:10.
9. Canals A., Gasbarre L.C., Boyd P.C., Almeria S., Zarlenga D.S. Cloning and expression of bovine interleukin-15: analysis and modulation of transcription by exogenous stimulation. J. Interferon Cytokine Res. 1997, 17:473-480.
10. Carson W.E., Giri J.G., Lindemann M.J., Linett M.L., Ahdieh M., Paxton R., Anderson D., Eisenmann J., Grabstein K., Caligiuri M.A. Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor. J. Exp. Med. 1994, 180:1395-1403.
11. Cooper M.A., Elliott J.M., Keyel P.A., Yang L., Carrero J.A., Yokoyama W.M. Cytokine-induced memory-like natural killer cells. Proc. Natl. Acad. Sci. U. S. A. 2009, 106:1915-1919.
12. Dean G.A., Barger A., Lavoy A. Cloning and expression of feline interleukin 15. Cytokine 2005, 29:77-83.
13. Dubois S., Mariner J., Waldmann T.A., Tagaya Y. IL-15Ralpha recycles and presents IL-15 in trans to neighboring cells. Immunity 2002, 17:537-547.
14. Elhmouzi-Younes J., Storset A.K., Boysen P., Laurent F., Drouet F. Bovine neonate natural killer cells are fully functional and highly responsive to interleukin-15 and to NKp46 receptor stimulation. Vet. Res. 2009, 40:54.
15. Endsley J.J., Endsley M.A., Estes D.M. Bovine natural killer cells acquire cytotoxic/effector activity following activation with IL-12/15 and reduce Mycobacterium bovis BCG in infected macrophages. J. Leukoc. Biol. 2006, 79:71-79.
16. Giri J.G., Ahdieh M., Eisenman J., Shanebeck K., Grabstein K., Kumaki S., Namen A., Park L.S., Cosman D., Anderson D. Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15. EMBO J. 1994, 13:2822-2830.
17. Goff W.L., Storset A.K., Johnson W.C., Brown W.C. Bovine splenic NK cells synthesize IFN-gamma in response to IL-12-containing supernatants from Babesia bovis-exposed monocyte cultures. Parasite Immunol. 2006, 28:221-228.
18. Grabstein K.H., Eisenman J., Shanebeck K., Rauch C., Srinivasan S., Fung V., Beers C., Richardson J., Schoenborn M.A., Ahdieh M., Johnson L., Alderson M.R., Watson J.D., Anderson D.M., Giri J.G. Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor. Science 1994, 264:965-968.
19. Hamilton M.J., Davis W.C. Culture conditions that optimize outgrowth of hybridomas. Methods Mol. Biol. 1995, 45:17-28.
20. Jost S., Quillay H., Reardon J., Peterson E., Simmons R.P., Parry B.A., Bryant N.N., Binder W.D., Altfeld M. Changes in cytokine levels and NK cell activation associated with influenza. PLoS ONE 2011, 6(9):e25060.
21. Koka R., Burkett P., Chien M., Chai S., Boone D.L., Ma A. Cutting edge: murine dendritic cells require IL-15R alpha to prime NK cells. J. Immunol. 2004, 173:3594-3598.
22. Kurys G., Tagaya Y., Bamford R., Hanover J.A., Waldmann T.A. The long signal peptide isoform and its alternative processing direct the intracellular trafficking of interleukin-15. J. Biol. Chem. 2000, 275:30653-30659.
23. Lanier L.L., Buck D.W., Rhodes L., Ding A., Evans E., Barney C., Phillips J.H. Interleukin 2 activation of natural killer cells rapidly induces the expression and phosphorylation of the Leu-23 activation antigen. J. Exp. Med. 1988, 167:1572-1585.
24. Leclercq G., Debacker V., De S.M., Plum J. Differential effects of interleukin-15 and interleukin-2 on differentiation of bipotential T/natural killer progenitor cells. J. Exp. Med. 1996, 184:325-336.
25. Lopez-Cabrera M., Santis A.G., Fernandez-Ruiz E., Blacher R., Esch F., Sanchez-Mateos P., Sanchez-Madrid F. Molecular cloning, expression, and chromosomal localization of the human earliest lymphocyte activation antigen AIM/CD69, a new member of the C-type animal lectin superfamily of signal-transmitting receptors. J. Exp. Med. 1993, 178:537-547.
26. Lucas M., Schachterle W., Oberle K., Aichele P., Diefenbach A. Dendritic cells prime natural killer cells by trans-presenting interleukin 15. Immunity 2007, 26:503-517.
27. Mrozek E., Anderson P., Caligiuri M.A. Role of interleukin-15 in the development of human CD56+ natural killer cells from CD34+ hematopoietic progenitor cells. Blood 1996, 87:2632-2640.
28. Newman K.C., Korbel D.S., Hafalla J.C., Riley E.M. Cross-talk with myeloid accessory cells regulates human natural killer cell interferon-gamma responses to malaria. PLoS Pathog. 2006, 2(12):e118.
29. Olsen I., Boysen P., Kulberg S., Hope J.C., Jungersen G., Storset A.K. Bovine NK cells can produce gamma interferon in response to the secreted mycobacterial proteins ESAT-6 and MPP14 but not in response to MPB70. Infect. Immun. 2005, 73:5628-5635.
30. Pillet A.H., Bugault F., Theze J., Chakrabarti L.A., Rose T. A programmed switch from IL-15- to IL-2-dependent activation in human NK cells. J. Immunol. 2009, 182:6267-6277.
31. Rubinstein M.P., Kovar M., Purton J.F., Cho J.H., Boyman O., Surh C.D., Sprent J. Converting IL-15 to a superagonist by binding to soluble IL-15R{alpha}. Proc. Natl. Acad. Sci. U. S. A. 2006, 103:9166-9171.
32. Sakaguchi S., Sakaguchi N., Asano M., Itoh M., Toda M. Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases. J. Immunol. 1995, 155:1151-1164.
33. Smith K.A. Interleukin-2: inception, impact, and implications. Science 1988, 240:1169-1176.
34. Storset A.K., Hasvold H.J., Valheim M., Brun-Hansen H., Berntsen G., Whist S.K., Djonne B., Press C.M., Holstad G., Larsen H.J. Subclinical paratuberculosis in goats following experimental infection. An immunological and microbiological study. Vet. Immunol. Immunopathol. 2001, 80:271-287.
35. Storset A.K., Kulberg S., Berg I., Boysen P., Hope J.C., Dissen E. NKp46 defines a subset of bovine leukocytes with natural killer cell characteristics. Eur. J. Immunol. 2004, 34:669-676.
36. Timmons B.W., Bar-Or O. Evidence of sex-based differences in natural killer cell responses to exercise and carbohydrate intake in children. Eur. J. Appl. Physiol. 2007, 101:233-240.
37. Tsujimoto H., Uchida T., Efron P.A., Scumpia P.O., Verma A., Matsumoto T., Tschoeke S.K., Ungaro R.F., Ono S., Seki S., Clare-Salzler M.J., Baker H.V., Mochizuki H., Ramphal R., Moldawer L.L. Flagellin enhances NK cell proliferation and activation directly and through dendritic cell-NK cell interactions. J. Leukoc. Biol. 2005, 78:888-897.
38. Ward A., Anderson M., Craggs R.I., Maltby J., Grahames C., Davies R.A., Finch D., Pattison D., Oakes H., Mallinder P.R. E. coli expression and purification of human and cynomolgus IL-15. Protein Expr. Purif. 2009, 68:42-48.