Differential responsiveness to 17β-estradiol of mesenchymal stem cells from postmenopausal women between osteoporosis and osteoarthritis

Osteoporosis International

Volumn 23, Issue 10, 2012, Pages 2469-2478

  Jin, W J ^a   Jiang, S D ^a   Jiang, L S ^a   Dai, L Y ^a  

^a SHANGHAI JIAO TONG UNIVERSITY   (China)

Author keywords

E2 (17 estradiol); Mesenchymal stem cells; Osteoarthritis; Osteogenic potential; Osteoporosis

Indexed keywords

ALKALINE PHOSPHATASE; CALCIUM; COLLAGEN TYPE 1; ESTRADIOL; LIPOPROTEIN LIPASE; MESSENGER RNA; OSTEOCALCIN; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA 2;

AGED; ARTICLE; CELL CULTURE; CLINICAL ARTICLE; CULTURE MEDIUM; ENZYME ACTIVITY; ESTROGEN DEFICIENCY; FEMALE; HUMAN; HUMAN CELL; MESENCHYMAL STEM CELL; OSTEOARTHRITIS; OSTEOPOROSIS; POSTMENOPAUSE; PRIORITY JOURNAL;

AGED; AGED, 80 AND OVER; ALKALINE PHOSPHATASE; CALCIUM; CELLS, CULTURED; ESTRADIOL; FEMALE; FEMUR HEAD; HIP FRACTURES; HUMANS; MESENCHYMAL STROMAL CELLS; OSTEOARTHRITIS, HIP; OSTEOCALCIN; OSTEOPOROSIS, POSTMENOPAUSAL; OSTEOPOROTIC FRACTURES;

EID: 84867332555     PISSN: 0937941X     EISSN: 14332965     Source Type: Journal    
DOI: 10.1007/s00198-011-1859-8     Document Type: Article

References (39)

1. Brandt KD, Dieppe P, Radin EL (2008) Etiopathogenesis of osteoarthritis. Rheum Dis Clin North Am 34:531-559
2. Hayami T, Pickarski M, Wesolowski GA, McLane J, Bone A, Destefano J, Rodan GA, Duong LT (2004) The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model. Arthritis Rheum 50:1193-1206
3. Bellido M, Lugo L, Roman-Blas JA, Castañeda S, Caeiro JR, Dapia S, Calvo E, Largo R, Herrero-Beaumont G (2010) Subchondral bone microstructural damage by increased remodelling aggravates experimental osteoarthritis preceded by osteoporosis. Arthritis Res Ther 12:R152
4. Dequeker J, Aerssens J, Luyten FP (2003) Osteoarthritis and osteoporosis: clinical and research evidence of inverse relationship. Aging Clin Exp Res 15:426-439
5. Avci D, Bachmann GA (2004) Osteoarthritis and osteoporosis in postmenopausal women: clinical similarities and differences. Menopause 11:615-621
6. Roux C, Fechtenbaum J, Briot K, Cropet C, Liu-Leage S, Marcelli C (2008) Inverse relationship between vertebral fractures and spine osteoarthritis in postmenopausal women with osteoporosis. Ann Rheum Dis 67:224-228
7. Zhang ZM, Li ZC, Jiang LS, Jiang SD, Dai LY (2010) Micro-CT and mechanical evaluation of subchondral trabecular bone structure between postmenopausal women with osteoarthritis and osteoporosis. Osteoporos Int 21:1383-1390
8. Lancianese SL, Kwok E, Beck CA, Lerner AL (2008) Predicting regional variations in trabecular bone mechanical properties within the human proximal tibia using MR imaging. Bone 43:1039-1046
9. Li B, Aspden RM (1997) Mechanical and material properties of the subchondral bone plate from the femoral head of patients with osteoarthritis or osteoporosis. Ann Rheum Dis 56:247-254
10. Li B, Marshall D, Roe M, Aspden RM (1999) The electron microscope appearance of the subchondral bone plate in the human femoral head in osteoarthritis and osteoporosis. J Anat 195:101-110
11. Sun SS, Ma HL, Liu CL, Huang CH, Cheng CK, Wei HW (2008) Difference in femoral head and neck material properties between osteoarthritis and osteoporosis. Clin Biomech 23(Suppl 1):S39-S47
12. Riggs BL, Khosla S, Melton LJ III (2002) Sex steroids and the construction and conservation of the adult skeleton. Endocr Rev 23:279-302
13. Sniekers YH, Weinans H, Bierma-Zeinstra SM, van Leeuwen JP, van Osch GJ (2008) Animal models for osteoarthritis: the effect of ovariectomy and estrogen treatment: a systematic approach. Osteoarthr Cartil 16:533-541
14. Roman-Blas JA, Castaneda S, Largo R, Herrero-Beaumont G (2009) Osteoarthritis associated with estrogen deficiency. Arthritis Res Ther 11:241
15. Wlucka AE, Cicuttini F, Spector TD (2000) Menopause, oestrogens and arthritis. Maturitas 35:183-199
16. Murphy JM, Dixon K, Beck S, Fabian D, Feldman A, Barry F (2002) Reduced chondrogenic and adipogenic activity of mesenchymal stem cells from patients with advanced osteoarthritis. Arthritis Rheum 46:704-713
17. Dudics V, Kunstár A, Kovács J, Lakatos T, Géher P, Gömör B, Monostori E, Uher F (2009) Chondrogenic potential of mesenchymal stem cells from patients with rheumatoid arthritis and osteoarthritis: measurements in a microculture system. Cells Tissues Organs 189:307-316
18. Scharstuhl A, Schewe B, Benz K, Gaissmaier C, Bühring HJ, Stoop R (2007) Chondrogenic potential of human adult mesenchymal stem cells is independent of age or osteoarthritis etiology. Stem Cells 25:3244-3251
19. Astudillo P, Ríos S, Pastenes L, Pino AM, Rodríguez JP (2008) Increased adipogenesis of osteoporotic human-mesenchymal stem cells (MSCs) characterizes by impaired leptin action. J Cell Biochem 103:1054-1065
20. Rodríguez JP, Ríos S, Fernandez M, Santibanez JF (2004) Differential activation of ERK1, 2 MAP kinase signaling pathway in mesenchymal stem cell from control and osteoporotic postmenopausal women. J Cell Biochem 92:745-754
21. Zhang ZM, Jiang LS, Jiang SD, Dai LY (2009) Osteogenic potential and responsiveness to leptin of mesenchymal stem cells between postmenopausal women with osteoarthritis and osteoporosis. J Orthop Res 27:1067-1073
22. Hess R, Pino AM, Ríos S, Fernández M, Rodríguez JP (2005) High affinity leptin receptors are present in human mesenchymal stem cells (MSCs) derived from control and osteoporotic donors. J Cell Biochem 94:50-57
23. Ogita M, Rached MT, Dworakowski E, Bilezikian JP, Kousteni S (2008) Differentiation and proliferation of periosteal osteoblast progenitors are differentially regulated by estrogens and intermittent parathyroid hormone administration. Endocrinology 149:5713-5723
24. Hong L, Sultana H, Paulius K, Zhang G (2009) Steroid regulation of proliferation and osteogenic differentiation of bone marrow stromal cells: a gender difference. J Steroid Biochem Mol Biol 114:180-185
25. Hong L, Colpan A, Peptan IA (2006) Modulations of 17-β estradiol on osteogenic and adipogenic differentiations of human mesenchymal stem cells. Tissue Eng 12:2747-2753
26. Jenei-Lanzl Z, Straub RH, Dienstknecht T, Huber M, Hager M, Grässel S, Kujat R, Angele MK, Nerlich M, Angele P (2010) Estradiol inhibits chondrogenic differentiation of mesenchymal stem cells via nonclassic signaling. Arthritis Rheum 62:1088-1096
27. Dai Z, Li Y, Quarles LD, Song T, Pan W, Zhou H, Xiao Z (2007) Resveratrol enhances proliferation and osteoblastic differentiation in human mesenchymal stem cells via ER-dependent ERK1/2 activation. Phytomedicine 14:806-814
28. Zhou S, Zilberman Y, Wassermann K, Bain SD, Sadovsky Y, Gazit D (2001) Estrogen modulates estrogen receptor α and β expression, osteogenic activity, and apoptosis in mesenchymal stem cells (MSCs) of osteoporotic mice. J Cell Biochem Suppl 36:144-155
29. Jiang LS, Zhang ZM, Jiang SD, Chen WH, Dai LY (2008) Differential bone metabolism between postmenopausal women with osteoarthritis and osteoporosis. J Bone Miner Res 23:475-483
30. Dai LY (1996) The relationship between osteoarthritis and osteoporosis in the hip. J Orthop Rheumatol 9:214-216
31. Justesen J, Stenderup K, Ebbesen EN, Mosekilde L, Steiniche T, Kassem M (2001) Adipocyte tissue volume in bone marrow is increased with aging and in patients with osteoporosis. Biogerontology 2:165-171
32. Parfitt AM, Villanueva AR, Foldes J, Rao DS (1995) Relations between histologic indices of bone formation: implications for the pathogenesis of spinal osteoporosis. J Bone Miner Res 10:466-473
33. Martínez J, Silva S, Santibanez JF (1996) Prostate-derived soluble factors block osteoblast differentiation in culture. J Cell Biochem 61:18-25
34. Leskela HV, Olkku A, Lehtonen S, Mahonen A, Koivunen J, Turpeinen M, Uusitalo J, Pelkonen O, Kangas L, Selander K, Lehenkari P (2006) Estrogen receptor a genotype confers interindividual variability of response to estrogen and testosterone in mesenchymalstemcell-derived osteoblasts. Bone 39:1026-1034
35. Logar DB, Komadina R, Prezelj J, Ostanek B, Trost Z, Marc J (2007) Expression of bone resorption genes in osteoarthritis and in osteoporosis. J Bone Miner Metab 25:219-225
36. Bergman RJ, Gazit D, Kahn AJ, Gruber H, McDougall S, Hahn TJ (1996) Age-related changes in osteogenic stem cells in mice. J Bone Miner Res 11:568-577
37. Zhou S, Greenberger JS, Epperly MW, Goff JP, Adler C, LeBoff MS, Glowacki J (2008) Age-related intrinsic changes in human bone-marrow derived mesenchymal stem cells and their differentiation to osteoblasts. Aging Cell 7:335-343
38. Rodriguez JP, Garat S, Gajardo H, Pino AM, Seitz G (1999) Abnormal osteogenesis in osteoporotic patients is reflected by altered mesenchymal stem cells dynamics. J Cell Biochem 75:414-423
39. Herrero-Beaumont G, Roman-Blas JA, Largo R, Berenbaum F, Castaneda S (2011) Bone mineral density and joint cartilage: four clinical settings of a complex relationship in osteoarthritis. Ann Rheum Dis 70:1523-1525