Controlling interneuron activity in Caenorhabditis elegans to evoke chemotactic behaviour

Nature

Volumn 490, Issue 7419, 2012, Pages 273-277

  Kocabas, Askin ^a,b   Shen, Ching Han ^a,b   Guo, Zengcai V ^c   Ramanathan, Sharad ^a,b,d,e,f  

^a HARVARD UNIVERSITY   (United States)

^b HARVARD UNIVERSITY   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^d ALLEN INSTITUTE FOR BRAIN SCIENCE   (United States)

^e HARVARD STEM CELL INSTITUTE   (United States)

^f HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL; CHEMOTAXIS; NEMATODE; NERVOUS SYSTEM; SENSORY SYSTEM;

ARTICLE; CAENORHABDITIS ELEGANS; CELL ACTIVITY; CELL MIGRATION; CELL REGENERATION; CELL STIMULATION; CHEMOTAXIS; INTERNEURON; MOLECULAR DYNAMICS; NERVE EXCITABILITY; NONHUMAN; PRIORITY JOURNAL; THERMORECEPTOR;

ANIMALS; BEHAVIOR, ANIMAL; CAENORHABDITIS ELEGANS; CHEMOTAXIS; ELECTRIC STIMULATION; INTERNEURONS; NEURONS;

ANIMALIA; CAENORHABDITIS ELEGANS;

EID: 84867328205     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature11431     Document Type: Article

References (33)

1. Brenner, S. The genetics of behaviour. Br. Med. Bull. 29, 269-271 (1973).
2. Brenner, S. The genetics of Caenorhabditis elegans. Genetics 77, 71-94 (1974).
3. Tsalik, E. L. & Hobert, O. Functional mapping of neurons that control locomotory behavior in Caenorhabditis elegans. J. Neurobiol. 56, 178-197 (2003).
4. Iino, Y. & Yoshida, K. Parallel use of two behavioral mechanisms for chemotaxis in Caenorhabditis elegans. J. Neurosci. 29, 5370-5380 (2009).
5. Pierce-Shimomura, J. T., Morse, T. M. & Lockery, S. R. The fundamental role of pirouettes in Caenorhabditis elegans chemotaxis. J. Neurosci. 19, 9557-9569 (1999).
6. Wakabayashi, T., Kitagawa, I. & Shingai, R. Neurons regulating the duration of forward locomotion in Caenorhabditis elegans. Neurosci. Res. 50, 103-111 (2004).
7. Gray, J. M., Hill, J. J. & Bargmann, C. I. A circuit for navigation in Caenorhabditis elegans. Proc. Natl Acad. Sci. USA 102, 3184-3191 (2005).
8. White, J. G., Southgate, E., Thomson, J. N.&Brenner, S. Thestructure of the nervous system of the nematode Caenorhabditis elegans. Phil. Trans. R. Soc. Lond. B 314, 1-340 (1986).
9. Ward, S. Chemotaxis by the nematode Caenorhabditis elegans: identification of attractants and analysis of the response by use of mutants. Proc. Natl Acad. Sci. USA 70, 817-821 (1973).
10. Izquierdo, E. J.& Lockery, S. R. Evolution and analysis of minimal neural circuits for klinotaxis in Caenorhabditis elegans. J. Neurosci. 30, 12908-12917 (2010).
11. Chalasani, S. H. et al. Dissecting a circuit for olfactory behaviour in Caenorhabditis elegans. Nature 450, 63-70 (2007).
12. Boyden, E. S., Zhang, F., Bamberg, E., Nagel, G. & Deisseroth, K. Millisecondtimescale, genetically targeted optical control of neural activity. Nature Neurosci. 8, 1263-1268 (2005).
13. Nagel, G. et al. Light activation of channelrhodopsin-2 in excitable cells of Caenorhabditis elegans triggers rapid behavioral responses. Curr. Biol. 15, 2279-2284 (2005).
14. Chow, B. Y. et al. High-performance genetically targetable optical neural silencing by light-driven proton pumps. Nature 463, 98-102 (2010).
15. Okazaki, A., Sudo, Y. & Takagi, S. Optical silencing of C. elegans cells with arch proton pump. PLoS ONE 7, e35370 (2012).
16. Guo, Z. V., Hart, A. C. & Ramanathan, S. Optical interrogation of neural circuits in Caenorhabditis elegans. Nature Methods 6, 891-896 (2009).
17. Leifer, A. M., Fang-Yen, C., Gershow, M.,Alkema, M. J.&Samuel, A. D. T.Optogenetic manipulation of neural activity in freely moving Caenorhabditis elegans. Nature Methods 8, 147-152 (2011).
18. Stirman, J. N. et al. Real-timemultimodal optical control of neurons andmuscles in freely behaving Caenorhabditis elegans. Nature Methods 8, 153-158 (2011).
19. Lockery, S. R. The computational worm: spatial orientation and its neuronal basis in C. elegans. Curr. Opin. Neurobiol. 21, 782-790 (2011).
20. Kim, D., Park, S., Mahadevan, L. & Shin, J. H. The shallow turn of a worm. J. Exp. Biol. 214, 1554-1559 (2011).
21. McIntire, S. L., Jorgensen, E., Kaplan, J. & Horvitz, H. R. The GABAergic nervous system of Caenorhabditis elegans. Nature 364, 337-341 (1993).
22. Granato, M., Schnabel, H. & Schnabel, R. pha-1, a selectable marker for gene transfer in C. elegans. Nucleic Acids Res. 22, 1762-1763 (1994).
23. Edwards, S. L. et al. A novel molecular solution for ultraviolet light detection in Caenorhabditis elegans. PLoS Biol. 6, e198 (2008).
24. Karasawa, S., Araki, T., Nagai, T., Mizuno, H. & Miyawaki, A. Cyan-emitting and orange-emitting fluorescent proteins as a donor/acceptor pair for fluorescence resonance energy transfer. Biochem. J. 381, 307-312 (2004).
25. Ramot D., Johnson B. E., Berry T. L. Jr, Carnell L. & Goodman M. B. The parallel worm tracker: a platform for measuring average speed and drug-induced paralysis in nematodes. PLoS ONE 3, e2208 (2008).
26. Merzlyak, E. M. et al. Bright monomeric red fluorescent protein with an extended fluorescence lifetime. Nature Methods 4, 555-557 (2007).
27. Hires, S. A., Tian, L. & Looger, L. L. Reporting neural activity with genetically encoded calcium indicators. Brain Cell Biol. 36, 69-86 (2008).
28. Troemel, E. R., Sagasti, A. & Bargmann, C. I. Lateral signaling mediated by axon contact and calcium entry regulates asymmetric odorant receptor expression in C. elegans. Cell 99, 387-398 (1999).
29. Hobert, O. et al. Regulation of interneuron function in the C. elegans thermoregulatory pathway by the ttx-3 LIMhomeobox gene. Neuron 19, 345-357 (1997).
30. Bendena, W. G. et al. A Caenorhabditis elegans allatostatin/galanin-like receptor NPR-9 inhibits local search behavior in response to feeding cues. Proc. Natl Acad. Sci. USA. 105, 1339-1342 (2008).
31. Tsalik, E. LIMhomeobox gene-dependent expression of biogenic amine receptors in restricted regions of the C. elegans nervous system. Dev. Biol. 263, 81-102 (2003).
32. Chou, J. H., Bargmann, C. I. & Sengupta, P. The Caenorhabditis elegans odr-2 gene encodes a novel Ly-6-related protein required for olfaction. Genetics 157, 211-224 (2001).
33. Boulin, T., Etchberger, J. F. & Hobert, O. Reporter gene fusions. WormBook (2006).