메뉴 건너뛰기




Volumn 2, Issue , 2012, Pages 142-147

Impaired immunomodulatory ability of bone marrow mesenchymal stem cells on CD4 + T cells in aplastic anemia

Author keywords

Aplastic anemia; Bone marrow mesenchymal stem cell; CD4 + T cells; Immunomodulation

Indexed keywords

GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 4; PROSTAGLANDIN E2; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA;

EID: 84867319476     PISSN: None     EISSN: 22112839     Source Type: Journal    
DOI: 10.1016/j.rinim.2012.07.002     Document Type: Article
Times cited : (26)

References (30)
  • 2
    • 33750628439 scopus 로고    scopus 로고
    • Current concepts in the pathophysiology and treatment of aplastic anemia
    • Young NS, Calado RT, Scheinberg P Current concepts in the pathophysiology and treatment of aplastic anemia. Blood 2006, 108:2509-2519.
    • (2006) Blood , vol.108 , pp. 2509-2519
    • Young, N.S.1    Calado, R.T.2    Scheinberg, P.3
  • 8
    • 0037103384 scopus 로고    scopus 로고
    • Intracellular interferon-gamma in circulating and marrow T cells detected by flow cytometry and the response to immunosuppressive therapy in patients with aplastic anemia
    • Sloand E, Kim S, Maciejewski JP, Tisdale J, Follmann D, Young NS Intracellular interferon-gamma in circulating and marrow T cells detected by flow cytometry and the response to immunosuppressive therapy in patients with aplastic anemia. Blood 2002, 100:1185-1191.
    • (2002) Blood , vol.100 , pp. 1185-1191
    • Sloand, E.1    Kim, S.2    Maciejewski, J.P.3    Tisdale, J.4    Follmann, D.5    Young, N.S.6
  • 9
    • 0037097528 scopus 로고    scopus 로고
    • Cutting edge: activation of the p38 mitogen-activated protein kinase signaling pathway mediates cytokine-induced hemopoietic suppression in aplastic anemia
    • Verma A, Deb DK, Sassano A, Kambhampati S, Wickrema A, Uddin S, Mohindru M, Van Besien K, Platanias LC Cutting edge: activation of the p38 mitogen-activated protein kinase signaling pathway mediates cytokine-induced hemopoietic suppression in aplastic anemia. Journal of Immunology 2002, 168:5984-5988.
    • (2002) Journal of Immunology , vol.168 , pp. 5984-5988
    • Verma, A.1    Deb, D.K.2    Sassano, A.3    Kambhampati, S.4    Wickrema, A.5    Uddin, S.6    Mohindru, M.7    Van Besien, K.8    Platanias, L.C.9
  • 11
    • 0029782323 scopus 로고    scopus 로고
    • Deficiency of CD34+ c-kit+ and CD34 + 38- hematopoietic precursors in aplastic anemia after immunosuppressive treatment
    • Manz CY, Nissen C, Wodnar-Filipowicz A Deficiency of CD34+ c-kit+ and CD34 + 38- hematopoietic precursors in aplastic anemia after immunosuppressive treatment. American Journal of Hematology 1996, 52:264-274.
    • (1996) American Journal of Hematology , vol.52 , pp. 264-274
    • Manz, C.Y.1    Nissen, C.2    Wodnar-Filipowicz, A.3
  • 12
    • 33644505823 scopus 로고    scopus 로고
    • Quantitative analysis of bone marrow CD34 cells in aplastic anemia and hypoplastic myelodysplastic syndromes
    • Matsui WH, Brodsky RA, Smith BD, Borowitz MJ, Jones RJ Quantitative analysis of bone marrow CD34 cells in aplastic anemia and hypoplastic myelodysplastic syndromes. Leukemia 2006, 20:458-462.
    • (2006) Leukemia , vol.20 , pp. 458-462
    • Matsui, W.H.1    Brodsky, R.A.2    Smith, B.D.3    Borowitz, M.J.4    Jones, R.J.5
  • 13
    • 0036430336 scopus 로고    scopus 로고
    • Stem cell defect in aplastic anemia: reduced long term culture-initiating cells (LTC-IC) in CD34+ cells isolated from aplastic anemia patient bone marrow
    • Rizzo S, Scopes J, Elebute MO, Papadaki HA, Gordon-Smith EC, Gibson FM Stem cell defect in aplastic anemia: reduced long term culture-initiating cells (LTC-IC) in CD34+ cells isolated from aplastic anemia patient bone marrow. Hematology Journal 2002, 3:230-236.
    • (2002) Hematology Journal , vol.3 , pp. 230-236
    • Rizzo, S.1    Scopes, J.2    Elebute, M.O.3    Papadaki, H.A.4    Gordon-Smith, E.C.5    Gibson, F.M.6
  • 16
    • 33745231146 scopus 로고    scopus 로고
    • Immune modulation by mesenchymal stem cells
    • Rasmusson I Immune modulation by mesenchymal stem cells. Experimental Cell Research 2006, 312:2169-2179.
    • (2006) Experimental Cell Research , vol.312 , pp. 2169-2179
    • Rasmusson, I.1
  • 18
    • 70350536359 scopus 로고    scopus 로고
    • Fetal BM-derived mesenchymal stem cells promote the expansion of human Th17 cells, but inhibit the production of Th1 cells
    • Guo Z, Zheng C, Chen Z, Gu D, Du W, Ge J, Han Z, Yang R Fetal BM-derived mesenchymal stem cells promote the expansion of human Th17 cells, but inhibit the production of Th1 cells. European Journal of Immunology 2009, 39:2840-2849.
    • (2009) European Journal of Immunology , vol.39 , pp. 2840-2849
    • Guo, Z.1    Zheng, C.2    Chen, Z.3    Gu, D.4    Du, W.5    Ge, J.6    Han, Z.7    Yang, R.8
  • 21
    • 77953042879 scopus 로고    scopus 로고
    • Poor potential of proliferation and differentiation in bone marrow mesenchymal stem cells derived from children with severe aplastic anemia
    • Chao YH, Peng CT, Harn HJ, Chan CK, Wu KH Poor potential of proliferation and differentiation in bone marrow mesenchymal stem cells derived from children with severe aplastic anemia. Annals of Hematology 2010, 89:715-723.
    • (2010) Annals of Hematology , vol.89 , pp. 715-723
    • Chao, Y.H.1    Peng, C.T.2    Harn, H.J.3    Chan, C.K.4    Wu, K.H.5
  • 23
    • 77951975599 scopus 로고    scopus 로고
    • Human umbilical cord mesenchymal stem cells hUC-MSCs exert immunosuppressive activities through a PGE2-dependent mechanism
    • Chen K, Wang D, Du WT, Han ZB, Ren H, Chi Y, Yang SG, Zhu D, Bayard F, Han ZC Human umbilical cord mesenchymal stem cells hUC-MSCs exert immunosuppressive activities through a PGE2-dependent mechanism. Clinical Immunology 2010, 135:448-458.
    • (2010) Clinical Immunology , vol.135 , pp. 448-458
    • Chen, K.1    Wang, D.2    Du, W.T.3    Han, Z.B.4    Ren, H.5    Chi, Y.6    Yang, S.G.7    Zhu, D.8    Bayard, F.9    Han, Z.C.10
  • 24
    • 77957998506 scopus 로고    scopus 로고
    • Effects of MSC co-injection on the reconstitution of aplastic anemia patient following hematopoietic stem cell transplantation
    • Jaganathan BG, Tisato V, Vulliamy T, Dokal I, Marsh J, Dazzi F, Bonnet D Effects of MSC co-injection on the reconstitution of aplastic anemia patient following hematopoietic stem cell transplantation. Leukemia 2010, 24:1791-1795.
    • (2010) Leukemia , vol.24 , pp. 1791-1795
    • Jaganathan, B.G.1    Tisato, V.2    Vulliamy, T.3    Dokal, I.4    Marsh, J.5    Dazzi, F.6    Bonnet, D.7
  • 25
    • 65549124547 scopus 로고    scopus 로고
    • Cotransplantation of haploidentical mesenchymal stem cells to enhance engraftment of hematopoietic stem cells and to reduce the risk of graft failure in two children with severe aplastic anemia
    • Fang B, Li N, Song Y, Li J, Zhao RC, Ma Y Cotransplantation of haploidentical mesenchymal stem cells to enhance engraftment of hematopoietic stem cells and to reduce the risk of graft failure in two children with severe aplastic anemia. Pediatric Transplantation 2009, 13:499-502.
    • (2009) Pediatric Transplantation , vol.13 , pp. 499-502
    • Fang, B.1    Li, N.2    Song, Y.3    Li, J.4    Zhao, R.C.5    Ma, Y.6
  • 26
    • 77954432661 scopus 로고    scopus 로고
    • Co-transfusion of haplo-identical hematopoietic and mesenchymal stromal cells to treat a patient with severe aplastic
    • Wang H, Wang Z, Xue M, Liu J, Yan H, Guo Z Co-transfusion of haplo-identical hematopoietic and mesenchymal stromal cells to treat a patient with severe aplastic. Cytotherapy 2010, 12:563-565.
    • (2010) Cytotherapy , vol.12 , pp. 563-565
    • Wang, H.1    Wang, Z.2    Xue, M.3    Liu, J.4    Yan, H.5    Guo, Z.6
  • 27
    • 78149439868 scopus 로고    scopus 로고
    • Human multipotent mesenchymal stromal cells use galectin-1 to inhibit immune effector cells
    • Gieseke F, Bohringer J, Bussolari R, Dominici M, Handgretinger R, Muller I Human multipotent mesenchymal stromal cells use galectin-1 to inhibit immune effector cells. Blood 2010, 116:3770-3779.
    • (2010) Blood , vol.116 , pp. 3770-3779
    • Gieseke, F.1    Bohringer, J.2    Bussolari, R.3    Dominici, M.4    Handgretinger, R.5    Muller, I.6
  • 28
    • 2942595706 scopus 로고    scopus 로고
    • Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation
    • Meisel R, Zibert A, Laryea M, Gobel U, Daubener W, Dilloo D Human bone marrow stromal cells inhibit allogeneic T-cell responses by indoleamine 2,3-dioxygenase-mediated tryptophan degradation. Blood 2004, 103:4619-4621.
    • (2004) Blood , vol.103 , pp. 4619-4621
    • Meisel, R.1    Zibert, A.2    Laryea, M.3    Gobel, U.4    Daubener, W.5    Dilloo, D.6
  • 29
    • 33846006154 scopus 로고    scopus 로고
    • Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells
    • Sato K, Ozaki K, Oh I, Meguro A, Hatanaka K, Nagai T, Muroi K, Ozawa K Nitric oxide plays a critical role in suppression of T-cell proliferation by mesenchymal stem cells. Blood 2007, 109:228-234.
    • (2007) Blood , vol.109 , pp. 228-234
    • Sato, K.1    Ozaki, K.2    Oh, I.3    Meguro, A.4    Hatanaka, K.5    Nagai, T.6    Muroi, K.7    Ozawa, K.8
  • 30
    • 38349053355 scopus 로고    scopus 로고
    • Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+ CD25 high FOXP3+ regulatory T cells
    • Selmani Z, Naji A, Zidi I, Favier B, Gaiffe E, Obert L, Borg C, Saas P, Tiberghien P, Rouas-Freiss N, Carosella ED, Deschaseaux F Human leukocyte antigen-G5 secretion by human mesenchymal stem cells is required to suppress T lymphocyte and natural killer function and to induce CD4+ CD25 high FOXP3+ regulatory T cells. Stem Cells 2008, 26:212-222.
    • (2008) Stem Cells , vol.26 , pp. 212-222
    • Selmani, Z.1    Naji, A.2    Zidi, I.3    Favier, B.4    Gaiffe, E.5    Obert, L.6    Borg, C.7    Saas, P.8    Tiberghien, P.9    Rouas-Freiss, N.10    Carosella, E.D.11    Deschaseaux, F.12


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.