-
1
-
-
30444454024
-
G-protein-coupled receptors: Past, present and future
-
Hill SJ (2006) G-protein-coupled receptors: past, present and future. Br J Pharmacol 147(Suppl 1):S27-S37
-
(2006)
Br J Pharmacol
, vol.147
, Issue.SUPPL. 1
-
-
Hill, S.J.1
-
2
-
-
77952354490
-
Seven transmem-brane receptors as shapeshifting proteins: The impact of allosteric modulation and functional selectivity on new drug discovery
-
Kenakin T, Miller LJ (2010) Seven transmem-brane receptors as shapeshifting proteins: the impact of allosteric modulation and functional selectivity on new drug discovery. Pharmacol Rev 62:265-304
-
(2010)
Pharmacol Rev
, vol.62
, pp. 265-304
-
-
Kenakin, T.1
Miller, L.J.2
-
3
-
-
77951844975
-
Teaching old receptors new tricks: Biasing seven-transmembrane receptors
-
Rajagopal S, Rajagopal K, Lefkowitz RJ (2010) Teaching old receptors new tricks: biasing seven-transmembrane receptors. Nat Rev Drug Discov 9:373-386
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 373-386
-
-
Rajagopal, S.1
Rajagopal, K.2
Lefkowitz, R.J.3
-
4
-
-
78650147139
-
Allostery at G protein-coupled receptor homo-and heterom-ers: Uncharted pharmacological landscapes
-
Smith NJ, Milligan G (2010) Allostery at G protein-coupled receptor homo-and heterom-ers: uncharted pharmacological landscapes. Pharmacol Rev 62:701-725
-
(2010)
Pharmacol Rev
, vol.62
, pp. 701-725
-
-
Smith, N.J.1
Milligan, G.2
-
5
-
-
61449236177
-
Analysis of receptor oli-gomerization by FRAP microscopy
-
Dorsch S, Klotz KN, Engelhardt S, Lohse MJ, Bunemann M (2009) Analysis of receptor oli-gomerization by FRAP microscopy. Nat Methods 6:225-230
-
(2009)
Nat Methods
, vol.6
, pp. 225-230
-
-
Dorsch, S.1
Klotz, K.N.2
Engelhardt, S.3
Lohse, M.J.4
Bunemann, M.5
-
6
-
-
39949085589
-
Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors
-
Lohse MJ, Nikolaev VO, Hein P, Hoffmann C, Vilardaga JP, Bunemann M (2008) Optical techniques to analyze real-time activation and signaling of G-protein-coupled receptors. Trends Pharmacol Sci 29:159-165
-
(2008)
Trends Pharmacol Sci
, vol.29
, pp. 159-165
-
-
Lohse, M.J.1
Nikolaev, V.O.2
Hein, P.3
Hoffmann, C.4
Vilardaga, J.P.5
Bunemann, M.6
-
7
-
-
0036241055
-
Visualization of interactions among bZIP and Rel family proteins in living cells using bimo-lecular fluorescence complementation
-
Hu CD, Chinenov Y, Kerppola TK (2002) Visualization of interactions among bZIP and Rel family proteins in living cells using bimo-lecular fluorescence complementation. Mol Cell 9:789-798
-
(2002)
Mol Cell
, vol.9
, pp. 789-798
-
-
Hu, C.D.1
Chinenov, Y.2
Kerppola, T.K.3
-
8
-
-
0035853040
-
Circularly permuted green fluorescent proteins engineered to sense Ca 2+
-
Nagai T, Sawano A, Park ES, Miyawaki A (2001) Circularly permuted green fluorescent proteins engineered to sense Ca 2+. Proc Natl Acad Sci USA 98:3197-3202
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 3197-3202
-
-
Nagai, T.1
Sawano, A.2
Park, E.S.3
Miyawaki, A.4
-
9
-
-
0034647238
-
Antiparallel leucine zipper-directed protein reassembly: Application to the green fluorescent protein
-
Ghosh I, Hamilton AD, Regan L (2000) Antiparallel leucine zipper-directed protein reassembly: application to the green fluorescent protein. J Am Chem Soc 122:5658-5659
-
(2000)
J Am Chem Soc
, vol.122
, pp. 5658-5659
-
-
Ghosh, I.1
Hamilton, A.D.2
Regan, L.3
-
10
-
-
77249173336
-
Bimolecular fluorescence complementation: Lighting up seven transmembrane domain receptor signalling networks
-
Rose RH, Briddon SJ, Holliday ND (2010) Bimolecular fluorescence complementation: lighting up seven transmembrane domain receptor signalling networks. Br J Pharmacol 159:738-750
-
(2010)
Br J Pharmacol
, vol.159
, pp. 738-750
-
-
Rose, R.H.1
Briddon, S.J.2
Holliday, N.D.3
-
11
-
-
48249132926
-
Bimolecular fluorescence complementation (BiFC) analysis as a probe of protein interactions in living cells
-
Kerppola TK (2008) Bimolecular fluorescence complementation (BiFC) analysis as a probe of protein interactions in living cells. Annu Rev Biophys 37:465-487
-
(2008)
Annu Rev Biophys
, vol.37
, pp. 465-487
-
-
Kerppola, T.K.1
-
12
-
-
63849341905
-
Fluorescent and bioluminescent protein-fragment complementation assays in the study of G protein-coupled receptor oligomerization and signaling
-
Vidi PA, Watts VJ (2009) Fluorescent and bioluminescent protein-fragment complementation assays in the study of G protein-coupled receptor oligomerization and signaling. Mol Pharmacol 75:733-739
-
(2009)
Mol Pharmacol
, vol.75
, pp. 733-739
-
-
Vidi, P.A.1
Watts, V.J.2
-
13
-
-
78650051609
-
WAVE forms hetero-and homo-oligomeric complexes at integrin junctions in Drosophila visualized by bimolecular fluorescence complementation
-
Gohl C, Banovic D, Grevelhorster A, Bogdan S (2010) WAVE forms hetero-and homo-oligomeric complexes at integrin junctions in Drosophila visualized by bimolecular fluorescence complementation. J Biol Chem 285:40171-40179
-
(2010)
J Biol Chem
, vol.285
, pp. 40171-40179
-
-
Gohl, C.1
Banovic, D.2
Grevelhorster, A.3
Bogdan, S.4
-
14
-
-
79251552527
-
Visualization of protein interactions in living Drosophila embryos by the bimolecular fluore-scence complementation assay
-
Hudry B, Viala S, Graba Y, Merabet S (2011) Visualization of protein interactions in living Drosophila embryos by the bimolecular fluore-scence complementation assay. BMC Biol 9:5
-
(2011)
BMC Biol
, vol.9
, pp. 5
-
-
Hudry, B.1
Viala, S.2
Graba, Y.3
Merabet, S.4
-
15
-
-
0037995710
-
Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis
-
Hu CD, Kerppola TK (2003) Simultaneous visualization of multiple protein interactions in living cells using multicolor fluorescence complementation analysis. Nat Biotechnol 21: 539-545
-
(2003)
Nat Biotechnol
, vol.21
, pp. 539-545
-
-
Hu, C.D.1
Kerppola, T.K.2
-
16
-
-
33745234272
-
Analysis of G protein betag-amma dimer formation in live cells using multicolor bimolecular fluorescence complementation demonstrates preferences of beta1 for particular gamma subunits
-
Mervine SM, Yost EA, Sabo JL, Hynes TR, Berlot CH (2006) Analysis of G protein betag-amma dimer formation in live cells using multicolor bimolecular fluorescence complementation demonstrates preferences of beta1 for particular gamma subunits. Mol Pharmacol 70:194-205
-
(2006)
Mol Pharmacol
, vol.70
, pp. 194-205
-
-
Mervine, S.M.1
Yost, E.A.2
Sabo, J.L.3
Hynes, T.R.4
Berlot, C.H.5
-
17
-
-
50449091328
-
Ligand-dependent oligomerization of dopamine D(2) and adenosine A(2A) receptors in living neuronal cells
-
Vidi PA, Chemel BR, Hu CD, Watts VJ (2008) Ligand-dependent oligomerization of dopamine D(2) and adenosine A(2A) receptors in living neuronal cells. Mol Pharmacol 74:544-551
-
(2008)
Mol Pharmacol
, vol.74
, pp. 544-551
-
-
Vidi, P.A.1
Chemel, B.R.2
Hu, C.D.3
Watts, V.J.4
-
18
-
-
77957125242
-
Oligomeric organization of the B-cell antigen receptor on resting cells
-
Yang J, Reth M (2010) Oligomeric organization of the B-cell antigen receptor on resting cells. Nature 467:465-469
-
(2010)
Nature
, vol.467
, pp. 465-469
-
-
Yang, J.1
Reth, M.2
-
19
-
-
6944227833
-
Ubiquitin-mediated fluorescence complementation reveals that Jun ubiquitinated by Itch/AIP 4 is localized to lysosomes
-
Fang D, Kerppola TK (2004) Ubiquitin-mediated fluorescence complementation reveals that Jun ubiquitinated by Itch/AIP4 is localized to lysosomes. Proc Natl Acad Sci USA 101:14782-14787
-
(2004)
Proc Natl Acad Sci USA
, vol.101
, pp. 14782-14787
-
-
Fang, D.1
Kerppola, T.K.2
-
20
-
-
13244296604
-
Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein
-
Cabantous S, Terwilliger TC, Waldo GS (2005) Protein tagging and detection with engineered self-assembling fragments of green fluorescent protein. Nat Biotechnol 23:102-107
-
(2005)
Nat Biotechnol
, vol.23
, pp. 102-107
-
-
Cabantous, S.1
Terwilliger, T.C.2
Waldo, G.S.3
-
21
-
-
70350738339
-
Bimolecular fluorescence complementation analysis of inducible protein interactions: Effects of factors affecting protein folding on fluorescent protein fragment association
-
Robida AM, Kerppola TK (2009) Bimolecular fluorescence complementation analysis of inducible protein interactions: effects of factors affecting protein folding on fluorescent protein fragment association. J Mol Biol 394:391-409
-
(2009)
J Mol Biol
, vol.394
, pp. 391-409
-
-
Robida, A.M.1
Kerppola, T.K.2
-
22
-
-
18144394763
-
Capturing protein interactions in the secretory pathway of living cells
-
Nyfeler B, Michnick SW, Hauri HP (2005) Capturing protein interactions in the secretory pathway of living cells. Proc Natl Acad Sci USA 102:6350-6355
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 6350-6355
-
-
Nyfeler, B.1
Michnick, S.W.2
Hauri, H.P.3
-
23
-
-
77952867655
-
Quantitative analysis of neuropep-tide y receptor association with beta-arrestin2 measured by bimolecular fluorescence complementation
-
Kilpatrick LE, Briddon SJ, Hill SJ, Holliday ND (2010) Quantitative analysis of neuropep-tide Y receptor association with beta-arrestin2 measured by bimolecular fluorescence complementation. Br J Pharmacol 160:892-906
-
(2010)
Br J Pharmacol
, vol.160
, pp. 892-906
-
-
Kilpatrick, L.E.1
Briddon, S.J.2
Hill, S.J.3
Holliday, N.D.4
-
24
-
-
58249120533
-
Applicability of superfolder YFP bimolecular fluorescence complementation in vitro
-
Ottmann C, Weyand M, Wolf A, Kuhlmann J (2009) Applicability of superfolder YFP bimolecular fluorescence complementation in vitro. Biol Chem 390:81-90
-
(2009)
Biol Chem
, vol.390
, pp. 81-90
-
-
Ottmann, C.1
Weyand, M.2
Wolf, A.3
Kuhlmann, J.4
-
25
-
-
78349235354
-
An improved bimo-lecular fluorescence complementation assay with a high signal-to-noise ratio
-
Kodama Y, Hu CD (2010) An improved bimo-lecular fluorescence complementation assay with a high signal-to-noise ratio. Biotechniques 49:793-805
-
(2010)
Biotechniques
, vol.49
, pp. 793-805
-
-
Kodama, Y.1
Hu, C.D.2
-
26
-
-
33646893689
-
Identifying off-target effects and hidden phe-notypes of drugs in human cells
-
MacDonald ML, Lamerdin J, Owens S, Keon BH, Bilter GK, Shang Z, Huang Z, Yu H, Dias J, Minami T, Michnick SW, Westwick JK (2006) Identifying off-target effects and hidden phe-notypes of drugs in human cells. Nat Chem Biol 2:329-337
-
(2006)
Nat Chem Biol
, vol.2
, pp. 329-337
-
-
MacDonald, M.L.1
Lamerdin, J.2
Owens, S.3
Keon, B.H.4
Bilter, G.K.5
Shang, Z.6
Huang, Z.7
Yu, H.8
Dias, J.9
Minami, T.10
Michnick, S.W.11
Westwick, J.K.12
-
27
-
-
79952390939
-
The Survival of Motor Neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of Poly(A) mRNA in primary motor neuron axons
-
Fallini C, Zhang H, Su Y, Silani V, Singer RH, Rossoll W, Bassell GJ (2011) The Survival of Motor Neuron (SMN) protein interacts with the mRNA-binding protein HuD and regulates localization of Poly(A) mRNA in primary motor neuron axons. J Neurosci 31:3914-3925
-
(2011)
J Neurosci
, vol.31
, pp. 3914-3925
-
-
Fallini, C.1
Zhang, H.2
Su, Y.3
Silani, V.4
Singer, R.H.5
Rossoll, W.6
Bassell, G.J.7
-
28
-
-
78951485032
-
Comprehensive characterization of interaction complexes of herpes simplex virus type 1 ICP22, UL3, UL4, and UL20.5
-
Xing J, Wang S, Lin F, Pan W, Hu CD, Zheng C (2011) Comprehensive characterization of interaction complexes of herpes simplex virus type 1 ICP22, UL3, UL4, and UL20.5. J Virol 85:1881-1886
-
(2011)
J Virol
, vol.85
, pp. 1881-1886
-
-
Xing, J.1
Wang, S.2
Lin, F.3
Pan, W.4
Hu, C.D.5
Zheng, C.6
-
29
-
-
47949102446
-
Sequential binding of cytosolic Phox complex to phagosomes through regulated adaptor proteins: Evaluation using the novel mono-meric Kusabira-Green System and live imaging of phagocytosis
-
Ueyama T, Kusakabe T, Karasawa S, Kawasaki T, Shimizu A, Son J, Leto TL, Miyawaki A, Saito N (2008) Sequential binding of cytosolic Phox complex to phagosomes through regulated adaptor proteins: evaluation using the novel mono-meric Kusabira-Green System and live imaging of phagocytosis. J Immunol 181:629-640
-
(2008)
J Immunol
, vol.181
, pp. 629-640
-
-
Ueyama, T.1
Kusakabe, T.2
Karasawa, S.3
Kawasaki, T.4
Shimizu, A.5
Son, J.6
Leto, T.L.7
Miyawaki, A.8
Saito, N.9
-
30
-
-
78049348351
-
Development of bimolecular fluorescence complementation using Dronpa for visualization of protein-protein interactions in cells
-
Lee YR, Park JH, Hahm SH, Kang LW, Chung JH, Nam KH, Hwang KY, Kwon IC, Han YS (2010) Development of bimolecular fluorescence complementation using Dronpa for visualization of protein-protein interactions in cells. Mol Imaging Biol 12:468-478
-
(2010)
Mol Imaging Biol
, vol.12
, pp. 468-478
-
-
Lee, Y.R.1
Park, J.H.2
Hahm, S.H.3
Kang, L.W.4
Chung, J.H.5
Nam, K.H.6
Hwang, K.Y.7
Kwon, I.C.8
Han, Y.S.9
-
31
-
-
38049115791
-
Split mCherry as a new red bimolecular fluorescence complementation system for visualizing protein-protein interactions in living cells
-
Fan JY, Cui ZQ, Wei HP, Zhang ZP, Zhou YF, Wang YP, Zhang XE (2008) Split mCherry as a new red bimolecular fluorescence complementation system for visualizing protein-protein interactions in living cells. Biochem Biophys Res Commun 367:47-53
-
(2008)
Biochem Biophys Res Commun
, vol.367
, pp. 47-53
-
-
Fan, J.Y.1
Cui, Z.Q.2
Wei, H.P.3
Zhang, Z.P.4
Zhou, Y.F.5
Wang, Y.P.6
Zhang, X.E.7
-
32
-
-
33746435428
-
An improved mRFP1 adds red to bimolecular fluorescence complementation
-
Jach G, Pesch M, Richter K, Frings S, Uhrig JF (2006) An improved mRFP1 adds red to bimolecular fluorescence complementation. Nat Methods 3:597-600
-
(2006)
Nat Methods
, vol.3
, pp. 597-600
-
-
Jach, G.1
Pesch, M.2
Richter, K.3
Frings, S.4
Uhrig, J.F.5
-
34
-
-
51049112029
-
Dopamine D2 receptors form higher order oligomers at physiological expression levels
-
Guo W, Urizar E, Kralikova M, Mobarec JC, Shi L, Filizola M, Javitch JA (2008) Dopamine D2 receptors form higher order oligomers at physiological expression levels. EMBO J 27: 2293-2304
-
(2008)
EMBO J
, vol.27
, pp. 2293-2304
-
-
Guo, W.1
Urizar, E.2
Kralikova, M.3
Mobarec, J.C.4
Shi, L.5
Filizola, M.6
Javitch, J.A.7
-
35
-
-
61449217021
-
Imaging chemokine receptor dimerization with fire fly luciferase complementation
-
Luker KE, Gupta M, Luker GD (2009) Imaging chemokine receptor dimerization with fire fly luciferase complementation. FASEB J 23: 823-834
-
(2009)
FASEB J
, vol.23
, pp. 823-834
-
-
Luker, K.E.1
Gupta, M.2
Luker, G.D.3
-
36
-
-
34247525991
-
Detection of transient protein-protein interactions by bimolecular fluorescence com plementation: The Abl-SH3 case
-
Morell M, Espargaro A, Aviles FX, Ventura S (2007) Detection of transient protein-protein interactions by bimolecular fluorescence com plementation: the Abl-SH3 case. Proteomics 7:1023-1036
-
(2007)
Proteomics
, vol.7
, pp. 1023-1036
-
-
Morell, M.1
Espargaro, A.2
Aviles, F.X.3
Ventura, S.4
-
37
-
-
56649106450
-
Adenosine A(2A) receptors assemble into higher-order oligomers at the plasma membrane
-
Vidi PA, Chen J, Irudayaraj JM, Watts VJ (2008) Adenosine A(2A) receptors assemble into higher-order oligomers at the plasma membrane. FEBS Lett 582:3985-3990
-
(2008)
FEBS Lett
, vol.582
, pp. 3985-3990
-
-
Vidi, P.A.1
Chen, J.2
Irudayaraj, J.M.3
Watts, V.J.4
-
38
-
-
49849084462
-
Detection of higher-order G protein-coupled receptor oli-gomers by a combined BRET-BiFC technique
-
Gandia J, Galino J, Amaral OB, Soriano A, Lluis C, Franco R, Ciruela F (2008) Detection of higher-order G protein-coupled receptor oli-gomers by a combined BRET-BiFC technique. FEBS Lett 582:2979-2984
-
(2008)
FEBS Lett
, vol.582
, pp. 2979-2984
-
-
Gandia, J.1
Galino, J.2
Amaral, O.B.3
Soriano, A.4
Lluis, C.5
Franco, R.6
Ciruela, F.7
-
39
-
-
33750843262
-
Fluorescent protein-based cellular assays analyzed by laser-scanning microplate cytometry in 1536-well plate format
-
Auld DS, Johnson RL, Zhang YQ, Veith H, Jadhav A, Yasgar A, Simeonov A, Zheng W, Martinez ED, Westwick JK, Austin CP, Inglese J (2006) Fluorescent protein-based cellular assays analyzed by laser-scanning microplate cytometry in 1536-well plate format. Methods Enzymol 414:566-589
-
(2006)
Methods Enzymol
, vol.414
, pp. 566-589
-
-
Auld, D.S.1
Johnson, R.L.2
Zhang, Y.Q.3
Veith, H.4
Jadhav, A.5
Yasgar, A.6
Simeonov, A.7
Zheng, W.8
Martinez, E.D.9
Westwick, J.K.10
Austin, C.P.11
Inglese, J.12
-
40
-
-
0037225952
-
A general method for the covalent labeling of fusion proteins with small molecules in vivo
-
Keppler A, Gendreizig S, Gronemeyer T, Pick H, Vogel H, Johnsson K (2003) A general method for the covalent labeling of fusion proteins with small molecules in vivo. Nat Biotechnol 21:86-89
-
(2003)
Nat Biotechnol
, vol.21
, pp. 86-89
-
-
Keppler, A.1
Gendreizig, S.2
Gronemeyer, T.3
Pick, H.4
Vogel, H.5
Johnsson, K.6
|