Scaffold pore space modulation through intelligent design of dissolvable microparticles

Methods in Molecular Biology

Volumn 868, Issue , 2012, Pages 71-89

  Liebschner, Michael A K ^a,b   Wettergreen, Matthew ^c  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b MICHAEL E DEBAKEY VETERANS AFFAIRS MEDICAL CENTER   (United States)

^c Caroline Collective ^*  (United States)

Author keywords

Bio additive fabrication; Microparticles; Pore space modulation; Scaffold micro architecture; Soft lithography

Indexed keywords

BIOPOLYMER; COLLAGEN; DIMETICONE; POLYMER; TISSUE SCAFFOLD; BAYSILON; BIOMATERIAL;

ARTICLE; BONE MASS; CORTICAL BONE; DRUG DELIVERY SYSTEM; DRUG RELEASE; HEMATOPOIESIS; HUMAN; LOCOMOTION; MICROPARTICLE; MUSCULOSKELETAL DISEASE; OSTEOBLAST; POROSITY; PRIORITY JOURNAL; RAPID PROTOTYPING; SHEAR STRESS; SOFT LITHOGRAPHY; SPACE; TISSUE ENGINEERING; TRABECULAR BONE; BIOLOGICAL MODEL; BONE; CHEMISTRY; EQUIPMENT DESIGN; HISTOLOGY; INSTRUMENTATION; MICROTECHNOLOGY; PERMEABILITY; SOLUBILITY; ULTRASTRUCTURE;

BIOCOMPATIBLE MATERIALS; BONE AND BONES; DIMETHYLPOLYSILOXANES; EQUIPMENT DESIGN; HUMANS; MICROTECHNOLOGY; MODELS, BIOLOGICAL; PERMEABILITY; POROSITY; SOLUBILITY; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84867304470     PISSN: 10643745     EISSN: None     Source Type: Book Series    
DOI: 10.1007/978-1-61779-764-4_5     Document Type: Article

References (35)

1. BosGW, Poot AA, Beugeling T, van Aken WG, Feijen J (1998) Small-diameter vascular graft prostheses: current status. Arch Physiol Biochem 106(2):100-115
2. BMUS (2008) The burden of musculoskeletal diseases in the United States. 1:1-19. Online report, http://:www.boneandjointburden.org/
3. Wettergreen MA, Bucklen B, Sun W, Liebschner MAK (2005) Computer-aided tissue engineering in whole bone replacement treatment. In: Proceedings of the ASME International mechanical engineering congress and exposition. Orlando, Florida
4. Kaech DL, Jinkins JR (2002) Concluding remarks: the present and future of spinal restabilization procedures. Elsevier, Amsterdam, The Netherlands
5. Kandziora F, Pflugmacher R, Kleemann R,Duda G, Wise DL, Trantolo DJ, Lewandrowski KU, (2002) Biomechanical analysis of biodegradable interbody fusion cages augmented with poly (propylene glycol-co-fumaric acid). Spine 27 (15):1644-1651
6. Riggs BL, Melton LJ 3rd, (1995) The worldwide problem of osteoporosis: insights afforded by epidemiology. Bone 17(5 Suppl):505S-511S
7. Laschke MW (2006) Angiogenesis in tissue engineering: breathing life into constructed tissue substitutes. Tissue Eng 12:2093-2104
8. Liebschner MAK, Wettergreen M (2003) Optimization of bone scaffold engineering for load bearing applications.Topics Tissue Eng 22:1-39
9. Liebschner MA, Muller R, Wimalawansa SJ, Rajapakse CS, Gunaratne GH (2005) Testing two predictions for fracture load using computer models of trabecular bone. Biophys J 89 (2):759-767
10. Mullender M, El AJ, El Haj AJ, Yang Y, van Duin MA, Burger EH, Klein-Nulend J (2004) Mechanotransduction of bone cells in vitro: mechanobiology of bone tissue. Med Biol Eng Comput 42(1):14-21
11. Beebe DJ, Moore JS, Bauer JM, Yu Q, Liu RH, Devadoss C, Jo BH (2000) Functional hydrogel structures for autonomous flow control inside microfluidic channels. Nature 404 (6778):588-590
12. Tan W, Desai TA (2003) Microfluidic patterning of cells in extracellular matrix biopolymers: effects of channel size, cell type, and matrix composition on pattern integrity. Tissue Eng 9(2):255-267
13. Xia Y, Qin D, Whitesides GM (1996) Microcontact printing with a cylindrical rolling stamp: a practical step toward automatic manufacturing of patterns with submicrometer-sized features. Adv Mater 8(12): 1015-1017
14. Tien J, Nelson CM, Chen CS (2002) Fabrication of aligned microstructures with a single elastomeric stamp. Proc Natl Acad Sci USA 99(4):1758-1762
15. Folch A, Toner M (1998) Cellular micropatterns on biocompatible materials. Biotechnol Prog 14(3):388-392
16. Rogers-Foy JM, Powers DL, Brosnan DA, Barefoot SF, Friedman RJ, LaBerge M (1999) Hydroxyapatite composites designed for antibiotic drug delivery and bone reconstruction: a caprine model. J Invest Surg 12(5):263-275
17. Timmer MD, Carter C, Ambrose CG, Mikos AG (2003) Fabrication of poly(propylene fumarate)-based orthopaedic implants by photo-crosslinking through transparent silicone molds. Biomaterials 24(25):4707-4714
18. Vozzi G, Flaim C, Ahluwalia A, Bhatia S (2003) Fabrication of PLGA scaffolds using soft lithography and microsyringe deposition. Biomaterials 24(14):2533-2540
19. Chiu DT, Jeon NL, Huang S, Kane RS, Wargo CJ, Choi IS, Ingber DE, Whitesides GM (2000) Patterned deposition of cells and proteins onto surfaces by using three-dimensional microfluidic systems. Proc Natl Acad Sci USA 97(6):2408-2413
20. Kane RS, Takayama S, Ostuni E, Ingber DE, Whitesides GM (1999) Patterning proteins and cells using soft lithography. Biomaterials 20(23-24):2363-2376
21. Xia Y, Whitesides G (1998) Soft lithography. Angew Chem Int Ed 37:550-575
22. Wettergreen MA, Timmer MD, Mikos AG, Liebschner MAK (2003) Modification of porogen surface to volume ratio can be used to optimize the permeability of scaffolds used in tissue engineering. In 5th international bone fluid flow workshop. Cleveland, OH, 2003
23. Agrawal CM, McKinney JS, Lanctot D, Athanasiou KA (2000) Effects of fluid flow on the in vitro degradation kinetics of biodegradable scaffolds for tissue engineering. Biomaterials 21(23):2443-2452
24. OBrien FJ, Harley BA, Yannas IV, Gibson LJ (2005) The effect of pore size on cell adhesion in collagen-GAG scaffolds. Biomaterials 26(4): 433-441
25. Dullien FAL (1979) Porous media: fluid transport and pore structure. Academic Press, New York, NY
26. Scheidegger A (1974) The physics of flow through porous media. University of Toronto Press, Toronto, p 353
27. Wu XJ, Liu WJ, Wang MY (2007) Modeling heterogeneous objects in CAD. Comput Aided Design Appl 4:731-740
28. Yang P, Qian XA (2006) B-spline-based approach to heterogeneous objects design and analysis. Comput Aided Design 39:95-111
29. Park SM, Deckard CR, Beaman JJ (2001) Volumetric multi-texturing for functionally graded material representation. In: Sixth ACM Solid Modeling Symposium 2001. Ann Arbor, MI, USA
30. Pratt MJ (2003) 3D modeling of material property variation for computer aided design and manufacture. In: Proceedings of the SIAM conference on mathematics of industry: challenges and frontiers, 2003, Toronto, Ontario, Canada
31. Wang MY, Lee CS, Wang X, Mei Y (2005) Design of multi-material compliant mechanisms using level set methods. J Mech Design 127(5):941-956
32. Kumar V, Dutta D (1998) An approach to modeling and representation of heterogeneous objects. ASME J Mech Design 120(4): 659-667
33. Jackson T (2000) Analysis of functionality graded material representation methods. Massachusetts Institute of Technology, Cambridge, MA
34. Jackson T, Liu H, Patrikalakis NM, Sachs EM, Cima MJ (1999) Modeling and designing functionality graded material components for fabrication with local composition control. Mater Design 20(2-3):63-75
35. Krams R, Wentzel JJ, Cespedes I, Vinke R, Carlier S, van der Steen AF, Lancee CT, Slager CJ (1999) Effect of catheter placement on 3-D velocity profiles in curved tubes resembling the human coronary system. Ultrasound Med Biol 25(5):803-810