An approach to glycobiology from glycolipidomics: Ganglioside molecular scanning in the brains of patients with Alzheimer's disease by TLC-Blot/matrix assisted laser desorption/ionization-time of flight MS

Biological and Pharmaceutical Bulletin

Volumn 35, Issue 10, 2012, Pages 1642-1647

  Taki, Takao ^a  

^a OTSUKA PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Alzheimer's disease; Ganglioside; Glycolipidomics; Imaging MS; Matrix assisted laser desorption ionization time of flight MS; TLC Blot

Indexed keywords

CERAMIDE; GANGLIOSIDE GD 1B; GANGLIOSIDE GT 1B;

ALZHEIMER DISEASE; ARTIFICIAL MEMBRANE; BIOACCUMULATION; DISEASE MARKER; GLYCOBIOLOGY; GLYCOLIPIDOMICS; GRAY MATTER; HIPPOCAMPUS; HUMAN; LIPID ANALYSIS; LIPID BRAIN LEVEL; LIPID MEMBRANE; LIPIDOMICS; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MEMBRANE BIOLOGY; MOLECULAR BIOLOGY; MOLECULAR IMAGING; PARKINSON DISEASE; POLYVINYLIDENE DIFLUORIDE MEMBRANE; REVIEW; THIN LAYER CHROMATOGRAPHY; ULTRAVIOLET RADIATION;

ALZHEIMER DISEASE; CHROMATOGRAPHY, THIN LAYER; GANGLIOSIDES; GLYCOMICS; HIPPOCAMPUS; HUMANS; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION;

EID: 84867255598     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.b12-00400     Document Type: Review

References (27)

1. Hakomori S, Yamamura S, Handa AK. Signal transduction through glyco(sphingo)lipids. Introduction and recent studies on glyco (sphingo)lipid-enriched microdomains. Ann. N. Y. Acad. Sci., 845 1 SPHINGOLIPIDS, 1-10 (1998).
2. Prinetti A, Iwabuchi K, Hakomori S. Glycosphingolipid-enriched signaling domain in mouse neuroblastoma Neuro2a cells. Mechanism of ganglioside-dependent neuritogenesis. J. Biol. Chem., 274, 20916-20924 (1999).
3. Janich P, Corbeil D. GM1 and GM 3 gangliosides highlight distinct lipid microdomains within the apical domain of epithelial cells. FEBS Lett., 581, 1783-1787 (2007).
4. Ikarashi K, Fujiwara H, Yamazaki Y, Goto J, Kaneko K, Kato H, Fujii S, Sasaki H, Fukumoto S, Furukawa K, Waki H. Impaired hippocampal long-term potentiation and failure of learning in β1,4-N- acetylgalactosaminyltransferase gene transgenic mice. Glycobiology, 21, 1373-1381 (2011).
5. Ariga T, McDonald MP, Yu RK. Role of ganglioside metabolism in the pathogenesis of Alzheimer's disease: A review. J. Lipid Res., 49, 1157-1175 (2008).
6. She JQ, Wang M, Zhu DM, Sun LG, Ruan DY. Effect of ganglioside on synaptic plasticity of hippocampus in lead-exposed rats in vivo. Brain Res., 1060, 162-169 (2005).
7. Grimm MO, Zinser EG, Grösgen S, Hundsdörfer B, Rothhaar TL, Burg VK, Kaestner L, Bayer TA, Lipp P, Müller U, Grimm HS, Hartmann T. Amyloid precursor protein (APP) mediated regulation of ganglioside homeostasis linking Alzheimer's disease pathology with ganglioside metabolism. PLoS ONE, 7, e34095 (2012).
8. Taki T, Handa S, Ishikawa D. Blotting of glycolipids and phospholipids from a high-performance thin-layer chromatogram to a polyvinylidene difluoride membrane. Anal. Biochem., 221, 312-316 (1994).
9. Taki T, Ishikawa D, Handa S, Kasama T. Direct mass spectrometric analysis of glycosphingolipid transferred to a polyvinylidene difluoride membrane by thin-layer chromatography blotting. Anal. Biochem., 225, 24-27 (1995).
10. Isobe T, Naiki M, Handa S, Taki T. A simple assay method for bacterial binding to glycosphingolipids on a polyvinylidene difluoride membrane after thin-layer chromatography blotting and in situ mass spectrometric analysis of the ligands. Anal. Biochem., 236, 35-40 (1996).
11. Ishikawa D, Kato T, Handa S, Taki T. New methods using polyvinylidene difluoride membranes to detect enzymes involved in glycosphingolipid metabolism. Anal. Biochem., 231, 13-19 (1995).
12. Kasama T, Hisano Y, Nakajima M, Handa S, Taki T. Microscale analysis of glycosphingolipids by TLC blotting/secondary ion mass spectrometry: a novel blood group A-active glycosphingolipid and changes in glycosphingolipid expression in rat mammary tumour cells with different metastatic potentials. Glycoconj. J., 13, 461-469 (1996).
13. Taki T, Ishikawa D. TLC blotting: application to microscale analysis of lipids and as a new approach to lipid-protein interaction. Anal. Biochem., 251, 135-143 (1997).
14. Goto-Inoue N, Hayasaka T, Taki T, Gonzalez TV, Setou M. A new lipidomics approach by thin-layer chromatography-blot-matrix- assisted laser desorption/ionization imaging mass spectrometry for analyzing detailed patterns of phospholipid molecular species. J. Chromatogr. A, 1216, 7096-7101 (2009).
15. Taki T, Gonzalez TV, Goto-Inoue N, Hayasaka T, Setou M. TLC blot (far-eastern blot) and its applications. Methods Mol. Biol., 536, 545-556 (2009).
16. Goto-Inoue N, Hayasaka T, Sugiura Y, Taki T, Li YT, Matsumoto M, Setou M. High-sensitivity analysis of glycosphingolipids by matrix-assisted laser desorption/ionization quadrupole ion trap time-of-flight imaging mass spectrometry on transfer membranes. J. Chromatogr. B, 870, 74-83 (2008).
17. Valdes-Gonzalez T, Goto-Inoue N, Hayasaka T, Ishiyama H, Setou M, Taki T. Imaging technology of complex lipid molecular species by a combination of TLC-Blot and MALDI-TOF MS. Special reference to human brain ganglioside molecular species. J. Glycom. Lipidom., S2-004 (2012).
18. Valdes-Gonzalez T, Goto-Inoue N, Hirano W, Ishiyama H, Hayasaka T, Setou M, Taki T. New approach for glyco- and lipidomics-molecular scanning of human brain gangliosides by TLC-Blot and MALDI-QIT-TOF MS. J. Neurochem., 116, 678-683 (2011).
19. Rosenberg A, Stern N. Changes in sphingosine and fatty acid components of the gangliosides in developing rat and human brain. J. Lipid Res., 7, 122-131 (1966).
20. Palestini P, Masserini M, Sonnino S, Giuliani A, Tettamanti G. Changes in the ceramide composition of rat forebrain gangliosides with age. J. Neurochem., 54, 230-235 (1990).
21. Valsecchi M, Palestini P, Chigorno V, Sonnino S. Age-related changes of the ganglioside long-chain base composition in rat cerebellum. Neurochem. Int., 28, 183-187 (1996).
22. Sonnino S, Chigorno V. Ganglioside molecular species containing C18- and C20-sphingosine in mammalian nervous tissues and neuronal cell cultures. Biochim. Biophys. Acta, 1469, 63-77 (2000).
23. Sugiura Y, Shimma S, Konishi Y, Yamada MK, Setou M. Imaging mass spectrometry technology and application on ganglioside study; visualization of age-dependent accumulation of C20-ganglioside molecular species in the mouse hippocampus. PLoS ONE, 3, e3232 (2008).
24. Goto-Inoue N, Hayasaka T, Zaima N, Setou M. Imaging mass spectrometry for lipidomics. Biochim. Biophys. Acta, 1811, 961-969 (2011).
25. Veloso A, Fernández R, Astigarraga E, Barreda-Gómez G, Manuel I, Giralt MT, Ferrer I, Ochoa B, Rodríguez-Puertas R, Fernández JA. Distribution of lipids in human brain. Anal. Bioanal. Chem., 401, 89-101 (2011).
26. Goto-Inoue N, Hayasaka T, Zaima N, Setou M. The specific localization of seminolipid molecular species on mouse testis during testicular maturation revealed by imaging mass spectrometry. Glycobiology, 19, 950-957 (2009).
27. Jackson SN, Woods AS. Direct profiling of tissue lipids by MALDI-TOF MS. J. Chromatogr. B, 877, 2822-2829 (2009).