New simple synthesis of quinoline-4-carbonitriles

Synlett

Volumn 23, Issue 18, 2012, Pages 2682-2686

  Bujok, Robert ^a   Trawczyski, Adam ^b   Wróbel, Zbigniew ^a   Wojciechowski, Krzysztof ^a  

^a INSTITUTE OF ORGANIC CHEMISTRY   (Poland)

^b WARSAW UNIVERSITY OF TECHNOLOGY   (Poland)

Author keywords

alkylation; ketones; nitriles; quinolines; reduction; tin

Indexed keywords

2 (5 CHLORO 2 NITROPHENYL) 4 OXOPENTANENITRILE; 2 (5 FLUORO 2 NITROPHENYL) 4 OXO 4 PHENYLBUTYRONITRILE; 2 NITROBENZYL CYANIDE; 2 PHENYL 6 (TRIFLUOROMETHYL)QUINOLINE; 2 PHENYLBENZO[H]QUINOLINE 4 CARBONITRILE; 2 TERT BUTYL 6 CHLOROQUINOLINE 4 CARBONITRILE; 2 TERT BUTYL 6 METHOXYQUINOLINE; 3 (BENZYLOXYMETHYL) 2 METHYL 7 PHENYLPYRROLO[3,2 H]QUINOLINE 9 CARBONITRILE; 3 OCTYL 2,8 DIPHENYL 3H PYRROLO[2,3 H]QUINOLINE 6 CARBONITRILE; 5,5 DIMETHYL 1 (1 OCTYL 4 NITRO 2 PHENYL 1H INDOL YL) 5 OXOHEXANENITRILE; 6 CHLORO 2 PHENYLQUINOLINE 4 CARBONITRILE; 8 TERT BUTYL 3 OCTYL 2 PHENYL 3H PYRROLO[2,3 H]QUINOLINE; ALPHA HALOMETHYL KETONE; CYANIDE; KETONE DERIVATIVE; KETONITRILE; QUINOLINE 4 CARBONITRILE DERIVATIVE; QUINOLINE DERIVATIVE; TIN CHLORIDE; UNCLASSIFIED DRUG;

ALKYLATION; ARTICLE; CHEMICAL ANALYSIS; SYNTHESIS;

EID: 84867237761     PISSN: 09365214     EISSN: 14372096     Source Type: Journal    
DOI: 10.1055/s-0032-1317380     Document Type: Article

References (18)

1. Solomon V. R., Lee H. Curr. Med. Chem.: 2011; 18 1488
2. Kaur K., Jain M., Reddy R. P., Jain R. Eur. J. Med. Chem.: 2010; 3245
3. Madapa S., Tusi Z., Batra S. Curr. Org. Chem.: 2008; 12 1116
4. Kouznetsov V. V., Méndez L. Y. V, Gomez C. M. M. Curr. Org. Chem.: 2005; 9 141
5. Okamoto T., Tani H. Chem. Pharm. Bull.: 1959; 7 925
6. Vu A. T., Cohn S. T., Manas E. S., Harris H. A., Mewshaw R. E. Bioorg. Med. Chem. Lett.: 2005; 15 4520
7. Banini S. R., Turner M. R., Cummings M. M., Soederberg B. C. G. Tetrahedron: 2011; 67 3603
8. Wróbel Z., Kwast A., Ma̧kosza M. Synthesis: 1993; 31
9. Wróbel Z., Ma̧kosza M. Tetrahedron: 1993; 49 5315
10. Zimmermann T., Sicker D., Pink M. J. Prakt. Chem.: 1993; 335 390
11. Ma̧kosza M. Synthesis: 2011; 2341
12. Ma̧kosza M. Chem. Soc. Rev.: 2010; 39 2855
13. Ma̧kosza M., Wojciechowski K. Chem. Rev.: 2004; 104 2631
14. Ma̧kosza M., Wojciechowski K. Heterocycles: 2001; 54 445
15. Leardini R., Nanni D., Tundo A., Zanardi G. Gazz. Chim. Ital.: 1989; 119 637
16. Miyashita A., Taido N., Sato S., Yamamoto K.-i, Ishida H., Higashino T. Chem. Pharm. Bull.: 1991; 39 282
17. Barros A. I. R. N. A, Silva A. M. S. Tetrahedron Lett.: 2003; 44 5893
18. Okuma K., Seto J.-i, Nagahora N., Shioji K. J. Heterocycl. Chem.: 2010; 47 1372