Protective effect of thalidomide against N-methyl-D-aspartate-induced retinal neurotoxicity

Journal of Neuroscience Research

Volumn 89, Issue 10, 2011, Pages 1596-1604

  Takada, Kazuhide ^a   Munemasa, Yasunari ^a   Kuribayashi, Junko ^a   Fujino, Hiromi ^a   Kitaoka, Yasushi ^a  

^a ST MARIANNA UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Apoptosis; NMDA; Retina

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; N METHYL DEXTRO ASPARTIC ACID; THALIDOMIDE; TRANSCRIPTION FACTOR RELA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; DEGENERATIVE DISEASE; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; INFLAMMATORY DISEASE; MALE; NEUROPROTECTION; NEUROTOXICITY; NICK END LABELING; NONHUMAN; PRIORITY JOURNAL; RAT; RETINA DISEASE; WESTERN BLOTTING;

ANIMALS; DRUG INTERACTIONS; IN SITU NICK-END LABELING; MALE; N-METHYLASPARTATE; NEUROPROTECTIVE AGENTS; NEUROTOXINS; RATS; RATS, WISTAR; RETINAL DEGENERATION; RETINAL GANGLION CELLS; THALIDOMIDE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 79961209466     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.22698     Document Type: Article

References (41)

1. Alkam T, Nitta A, Mizoguchi H, Saito K, Seshima M, Itoh A, Yamada K, Nabeshima T. 2008. Restraining tumor necrosis factor-α by thalidomide prevents the amyloid beta-induced impairment of recognition memory in mice. Behav Brain Res 189: 100-106.
2. Andera L. 2009. Signaling activated by the death receptors of the TNFR family. Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 153: 173-180.
3. Besancon E, Guo S, Lok J, Tymianski M, Lo EH. 2008. Beyond NMDA and AMPA glutamate receptors: emerging mechanisms for ionic imbalance and cell death in stroke. Trends Pharmacol Sci 29: 268-275.
4. Bessero AC, Chiodini F, Rungger-Brändle E, Bonny C, Clarke PG. 2010. Role of the c-Jun N-terminal kinase pathway in retinal excitotoxicity, and neuroprotection by its inhibition. J Neurochem 113: 1307-1318.
5. Chen HS, Lipton SA. 2006. The chemical biology of clinically tolerated NMDA receptor antagonists. J Neurochem 97: 1611-1626.
6. Chen HS, Pellegrini JW, Aggarwal SK, Lei SZ, Warach S, Jensen FE, Lipton SA. 1992. Open-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicity. J Neurosci 12: 4427-4436.
7. D'Amato RJ, Loughnan MS, Flynn E, Folkman J. 1994. Thalidomide is an inhibitor of angiogenesis. Proc Natl Acad Sci U S A 91: 4082-4085.
8. Danesh-Meyer HV, Levin LA. 2009. Neuroprotection: extrapolating from neurologic diseases to the eye. Am. J Ophthalmol 148: 186-191.
9. Diem R, Meyer R, Weishaupt JH, Bahr M. 2001. Reduction of potassium currents and phosphatidylinositol 3-kinase-dependent AKT phosphorylation by tumor necrosis factor-(α) rescues axotomized retinal ganglion cells from retrograde cell death in vivo. J Neurosci 21: 2058-2066.
10. Fan W, Cooper NG. 2009. Glutamate-induced NFkappaB activation in the retina. Invest Ophthalmol Vis Sci 50: 917-925.
11. Fontaine V, Mohand-Said S, Hanoteau N, Fuchs C, Pfizenmaier K, Eisel U. 2002. Neurodegenerative and neuroprotective effects of tumor Necrosis factor (TNF) in retinal ischemia: opposite roles of TNF receptor 1 and TNF receptor 2. J Neurosci 22: RC216.
12. Franks ME, Macpherson G., Figg WD. 2004. Thalidomide. Lancet 363: 1802-1811.
13. Glass CK, Saijo K, Winner B, Marchetto MC, Gage FH. 2010. Mechanisms underlying inflammation in neurodegeneration. Cell 140: 918-934.
14. Hashimoto Y. 2008. Thalidomide as a multi-template for development of biologically active compounds. Arch Pharm Chem Life Sci 341: 536-547.
15. Hyakkoku K, Nakajima Y, Izuta H, Shimazwa M, Yamamoto T, Shibata N, Hara H. 2009. Thalidomide protects against ischemic neuronal damage induced by focal cerebral ischemia in mice. Neuroscience 159: 760-769.
16. Inomata Y, Nakamura H, Tanito M, Teratani A, Kawaji T, Kondo N, Yodoi J, Tanihara H. 2006. Thioredoxin inhibits NMDA-induced neurotoxicity in the rat retina. J Neurochem 98: 372-385.
17. Ito T, Ando H, Suzuki T, Ogura T, Hotta K, Imamura Y, Yamaguchi Y, Handa H. 2010. Identification of a primary target of thalidomide teratogenicity. Science 327: 1345-1350.
18. Keifer JA, Guttridge DC, Ashburner BP, Baldwin ASJr. 2001. Inhibition of NF-κB activity by thalidomide through suppression of IκB kinase activity. J Biol Chem. 276: 22382-22387.
19. Kiaei M, Petri S, Kipiani K, Gardian G, Choi DK, Chen J, Calingasan NY, Schafer P, Muller GW, Stewart C, Hensley K, Beal MF. 2006. Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis. J Neurosci 26: 2467-2473.
20. Kitaoka Y, Kumai T, Isenoumi K, Kitaoka Y, Motoki M, Kobayashi S, Ueno S. 2003. Neuroprotective effect of nitric oxide against NMDA-induced neurotoxicity in the rat retina is associated with tyrosine hydroxylase expression. Brain Res 977: 46-54.
21. Kitaoka Y, Kumai T, Kitaoka Y, Lam TT, Munemasa Y, Isenoumi K, Motoki M, Kuribayashi K, Kogo J, Kobayashi S, Ueno S. 2004. Nuclear factor-kappa B p65 in NMDA-induced retinal neurotoxicity. Brain Res Mol Brain Res 131: 8-16.
22. Kitaoka Y, Kitaoka Y, Kwong JM, Ross-Cisneros FN, Wang J, Tsai RK, Sadun AA, Lam TT. 2006. TNF-α-induced optic nerve degeneration and nuclear factor-kappaB p65. Invest Ophthalmol Vis Sci 47: 1448-1457.
23. Kuribayashi K, Kitaoka Y, Kumai T, Munemasa Y, Kitaoka Y, Isenoumi K, Motoki M, Kogo J, Hayashi Y, Kobayashi S, Ueno S. 2006. Neuroprotective effect of atrial natriuretic peptide against NMDA-induced neurotoxicity in the rat retina. Brain Res 1071: 34-41.
24. Lepper ER, Smith NF, Cox MC, Scripture CD, Figg WD. 2006. Thalidomide metabolism and hydrolysis: mechanisms and implications. Curr Drug Metab 7: 677-685.
25. Lipton SA. 2004. Failures and successes of NMDA receptor antagonists: molecular basis for the use of open-channel blockers like memantine in the treatment of acute and chronic neurologic insults. NeuroRx 1: 101-110.
26. Lipton SA, Rosenberg PA. 1994. Excitatory amino acids as a final common pathway for neurologic disorders. N Engl J Med 330: 613-622.
27. Munemasa Y, Ohtani-Kaneko R, Kitaoka Y, Kuribayashi K, Isenoumi K, Kogo J, Yamashita K, Kumai T, Kobayashi S, Hirata K, Ueno S. 2005. Contribution of mitogen-activated protein kinases to NMDA-induced neurotoxicity in the rat retina. Brain Res 1044: 227-240.
28. Munemasa, Y, Ohtani-Kaneko R, Kitaoka Y, Kitaoka Y, Kumai T, Kitaoka Y, Hayashi Y, Watanabe M, Takeda H, Hirata K, Ueno S. 2006. Pro-apoptotic role of C-Jun in NMDA-induced neurotoxicity in the rat retina. J Neurosci Res 83: 907-918.
29. Nakazawa T, Nakazawa C, Matsubara A, Noda K, Hisatomi T, She H, Michaud N, Hafezi-Moghadam A, Miller JW, Benowitz LI. 2006. Tumor necrosis factor-α mediates oligodendrocyte death and delayed retinal ganglion cell loss in a mouse model of glaucoma. J Neurosci 26: 12633-12641.
30. Raje N, Anderson K. 1999. Thalidomide-a revival story. N Engl J Med 341: 1606-1609.
31. Rodrigues GB, Passos GF, Di Giunta G, Figueiredo CP, Rodrigues EB, Grumman AJr, Medeiros R, Calixto JB. 2007. Preventive and therapeutic anti-inflammatory effects of systemic and topical thalidomide on endotoxin-induced uveitis in rats. Exp Eye Res 84: 553-560.
32. Ryu JK, McLarnon JG. 2008. Thalidomide inhibition of perturbed vasculature and glial-derived tumor necrosis factor-α in an animal model of inflamed Alzheimer's disease brain. Neurobiol Dis 29: 254-266.
33. Sampaio EP, Sarno EN, Galilly R, Cohn ZA, Kaplan G. 1991. Thalidomide selectively inhibits tumor necrosis factor α production by stimulated human monocytes. J Exp Med 173: 699-703.
34. Shanbhag PS, Viswanath V, Torsekar RG. 2006. Thalidomide: current status. Indian J Dermatol Venereol Leprol 72: 75-80.
35. Shen Y, Liu XL, Yang XL. 2006. N-methyl-D-aspartate receptors in the retina. Mol Neurobiol 34: 163-179.
36. Shinpo K, Kikuchi S, Moriwaka F, Tashiro K. 1999. Protective effects of the TNF-ceramide pathway against glutamate neurotoxicity on cultured mesencephalic neurons. Brain Res 819: 170-173.
37. Siliprandi R, Canella R, Carmignoto G, Schiavo N, Zanellato A, Zanoni R, Vantini G. 1992. N-methyl-D-aspartate-induced neurotoxicity in the adult rat retina. Vis Neurosci 8: 567-573.
38. Takahashi Y, Katai N, Murata T, Taniguchi SI, Hayashi T. 2007. Development of spontaneous optic neuropathy in NF-kappaBetap50-deficient mice: requirement for NF-kappaBetap50 in ganglion cell survival. Neuropathol Appl Neurobiol 33: 692-705.
39. Tamatani M, Che YH, Matsuzaki H, Ogawa S, Okado H, Miyake S, Mizuno T, Tohyama M. 1999. Tumor necrosis factor induces Bcl-2 and Bcl-x expression through NFkappaB activation in primary hippocampal neurons. J Biol Chem 274: 8531-8538.
40. Wojda U, Salinska E, Kuznicki J. 2008. Calcium ions in neuronal degeneration. IUBMB Life 60: 575-590.
41. Zou J, Crews F. 2006. CREB and NF-kappaB transcription factors regulate sensitivity to excitotoxic and oxidative stress induced neuronal cell death. Cell Mol Neurobiol 26: 385-405.