The PtdIns3P-Binding Protein Phafin 2 Mediates Epidermal Growth Factor Receptor Degradation by Promoting Endosome Fusion

Traffic

Volumn 13, Issue 11, 2012, Pages 1547-1563

  Pedersen, Nina Marie ^a,b,c   Raiborg, Camilla ^a,b   Brech, Andreas ^a,b   Skarpen, Ellen ^a,b   Roxrud, Ingrid ^a   Platta, Harald W ^a   Liestøl, Knut ^b,c,d   Stenmark, Harald ^a,b,c  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b UNIVERSITY OF OSLO   (Norway)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

^d UNIVERSITY OF OSLO   (Norway)

Author keywords

EEA1; Endocytosis; Endosome fusion; Epidermal growth factor receptor; Membrane traffic; Rab5

Indexed keywords

BINDING PROTEIN; DEXTRAN; EARLY ENDOSOME ANTIGEN 1; EPIDERMAL GROWTH FACTOR RECEPTOR; MYOTUBULARIN RELATED PROTEIN 4; PHAFIN2; PHOSPHATIDYLINOSITOL 3 PHOSPHATE; PROTEIN PX KINASE; PROTEOME; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL FUSION; CELL TRANSPORT; CONTROLLED STUDY; ENDOSOME; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; MEMBRANE BINDING; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN TARGETING; SIGNAL TRANSDUCTION;

AMINO ACID MOTIFS; ENDOCYTOSIS; ENDOSOMES; EPIDERMAL GROWTH FACTOR; HELA CELLS; HIGH-THROUGHPUT SCREENING ASSAYS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; NERVE TISSUE PROTEINS; ORGANELLE SIZE; PROTEIN INTERACTION DOMAINS AND MOTIFS; PROTEIN TYROSINE PHOSPHATASES, NON-RECEPTOR; PROTEIN-SERINE-THREONINE KINASES; PROTEOLYSIS; PROTEOME; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA, SMALL INTERFERING; TWO-HYBRID SYSTEM TECHNIQUES; UP-REGULATION; VESICULAR TRANSPORT PROTEINS;

EID: 84867230859     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2012.01400.x     Document Type: Article

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