Pharmacokinetics and tolerance of dehydroandrographolide succinate injection after intravenous administration in healthy Chinese volunteers

Acta Pharmacologica Sinica

Volumn 33, Issue 10, 2012, Pages 1332-1336

  Chen, Qian ^a   Liu, Yun ^a   Liu, Yan Mei ^a   Liu, Gang Yi ^a   Zhang, Meng Qi ^a   Jia, Jing Ying ^a   Lu, Chuan ^a   Yu, Chen ^a  

^a SHANGHAI XUHUI CENTRAL HOSPITAL   (China)

Author keywords

dehydroandrographolide succinate; herbal medicine; LC MS MS analysis; pharmacokinetics; tolerance

Indexed keywords

DEHYDROANDROGRAPHOLIDE SUCCINATE; HERBACEOUS AGENT; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; CHINESE; CROSSOVER PROCEDURE; DRUG BLOOD LEVEL; DRUG HALF LIFE; DRUG SAFETY; DRUG TOLERANCE; DRUG URINE LEVEL; FEMALE; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; MALE; NORMAL HUMAN; RANDOMIZED CONTROLLED TRIAL; STOMACH PAIN; TANDEM MASS SPECTROMETRY;

ADOLESCENT; ADULT; ANTIVIRAL AGENTS; CHINA; CROSS-OVER STUDIES; DITERPENES; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUGS, CHINESE HERBAL; FEMALE; HALF-LIFE; HUMANS; INFUSIONS, INTRAVENOUS; MALE; METABOLIC CLEARANCE RATE; MOLECULAR STRUCTURE; SEX FACTORS; YOUNG ADULT;

EID: 84867213508     PISSN: 16714083     EISSN: 17457254     Source Type: Journal    
DOI: 10.1038/aps.2012.79     Document Type: Article

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