Calcium sensing receptor regulates cardiomyocyte function through nuclear calcium

Cell Biology International

Volumn 36, Issue 10, 2012, Pages 937-943

  Zhong, Xin ^a   Liu, Jun ^b   Lu, Fanghao ^a   Wang, Yuwen ^b   Zhao, Yajun ^a   Dong, Shiyun ^a   Leng, Xiaoning ^a   Jia, Jing ^a   Ren, Huan ^a   Xu, Changqing ^a   Zhang, Weihua ^a  

^a HARBIN MEDICAL UNIVERSITY   (China)

^b THE SECOND AFFILIATED HOSPITAL OF HARBIN MEDICAL UNIVERSITY   (China)

Author keywords

Calcium sensing receptor (car); hypertrophy; Inositol 1,4,5 trisphosphate receptor (IP3R); nuclear Ca2+ release

Indexed keywords

CALCINEURIN; CALCIUM ION; CALCIUM SENSING RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR TYPE 1; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR TYPE 2; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR TYPE 3; RYANODINE RECEPTOR; RYANODINE RECEPTOR 2; TRANSCRIPTION FACTOR NFAT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM SIGNALING; CALCIUM TRANSPORT; CELL FUNCTION; CELL NUCLEUS TRANSPLANTATION; CELL SIZE; CELL STRUCTURE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; HEART MUSCLE CELL; HEART VENTRICLE HYPERTROPHY; MOLECULAR BIOLOGY; NEWBORN; NONHUMAN; PROTEIN CONTENT; PROTEIN EXPRESSION; PROTEIN TRANSPORT; RAT; SIGNAL TRANSDUCTION;

ANIMALS; CALCINEURIN; CALCIUM; CALCIUM SIGNALING; CARDIOMEGALY; CELL NUCLEUS; CELLS, CULTURED; INOSITOL 1,4,5-TRISPHOSPHATE; INOSITOL 1,4,5-TRISPHOSPHATE RECEPTORS; MYOCYTES, CARDIAC; NFATC TRANSCRIPTION FACTORS; RATS; RATS, WISTAR; RECEPTORS, CALCIUM-SENSING;

RATTUS;

EID: 84867182565     PISSN: 10656995     EISSN: 10958355     Source Type: Journal    
DOI: 10.1042/CBI20110594     Document Type: Article

References (21)

1. Aronow BJ, Toyokawa T, Canning A, Haghighi K, Delling U, Kranias E et al. Divergent transcriptional responses to independent genetic causes of cardiac hypertrophy. Physiol Genomics 2001;6:19-28.
2. Bare DJ, Kettlun CS, Liang M, Bers DM, Mignery GA. Cardiac type 2 inositol 1,4,5-trisphosphate receptor: interaction and modulation by calcium/calmodulin-dependent protein kinase II. J Biol Chem 2005;280:15912-20.
3. Brown EM, MacLeod RJ. Extracellular calcium sensing and extracellular calcium signaling. Physiol Rev 2001;81:239-97.
4. Chesley A, Lundberg MS, Asai T, Xiao RP, Ohtani S, Lakatta EG et al. The beta(2)-adrenergic receptor delivers an antiapoptotic signal to cardiac myocytes through G(i)-dependent coupling to phosphatidylinositol 39-kinase. Circ Res 2000;87:1172-9.
5. Echevarría W, Leite MF, Guerra MT, Zipfel WR, Nathanson MH. Regulation of calcium signals in the nucleus by a nucleoplasmic reticulum. Nat Cell Biol 2003;5:440-6.
6. Giorgi C, Ito K, Lin HK, Santangelo C, Wieckowski MR, Lebiedzinska M et al. PML regulates apoptosis at endoplasmic reticulum by modulating calcium release. Science 2010;330:1247-51.
7. 2+ regulates cardiomyocyte function. Cell Calcium 2008;44:230-42.
8. 2+ release is a nexus for hypertrophic signaling in cardiac myocytes. Mol. Cell 2009;33:472-82.
9. 2+ sparks and waves mediated by inositol 1,4,5-trisphosphate receptors in neonatal rat cardiomyocytes. Cell Calcium 2008;43:165-74.
10. 2+ signalling and the generation of arrhythmias in rat atrial myocytes. J Physiol 2002;541:395-409.
11. Marius P, Guerra MT, Nathanson MH, Ehrlich BE, Leite MF. Calcium release from ryanodine receptors in the nucleoplasmic reticulum. Cell Calcium 2006;39:65-73.
12. Mather EL. DNA-Binding factors of B Lymphoid cells are susceptible to limited proteolytic cleavage during nuclear extract preparation. Mol Cell Biol 1988;8:1812-5.
13. 2+ oscillations in vascular myocytes. Arterioscler Thromb Vasc Biol 2003;23:1567-75.
14. Nakayama H, Bodi I, Maillet M, DeSantiago J, Domeier TL, Mikoshiba K et al. The IP3 receptor regulates cardiac hypertrophy in response to select stimuli. Circ Res 2010;107:659-66.
15. 2+ entry. Cell 2002;111:529-41.
16. Quignard JF, Mironneau J, Carricaburu V, Fournier B, Babich A, Nurnberg B et al. Phosphoinositide 3-kinase mediates angiotensin II-induced stimulation of L-type calcium channels in vascular myocytes. J Biol Chem 2001;276:32545-51.
17. Sun Y, Liu M, Li H, Shi S, Zhao Y, Wang R et al. Calcium-sensing receptor induces rat neonatal ventricular cardiomyocyte apoptosis. Biochem Biophys Res Commun 2006;350:942-8.
18. Tu CL, Chang W, Bikle DD. The role of the calcium sensing receptor in regulating intracellular calcium handling in human epidermal keratinocytes. J Invest Dermatol 2007;127:1074-83.
19. Wilkins BJ, Dai YS, Bueno OF, Parsons SA, Xu J, Plank DM et al. Calcineurin/NFAT coupling participates in pathological, but not physiological, cardiac hypertrophy. Circ Res 2004;94:110-8.
20. 2+ signaling in cardiac myocyte excitation-transcription coupling. J Clin Invest 2006;116:675-82.
21. 2+ signalling in cat atrial excitation-contraction coupling and arrhythmias. J Physiol 2004;555:607-15.