Neural differentiation of mesenchymal stem cells influences chemotactic responses to HGF

Journal of Cellular Physiology

Volumn 228, Issue 1, 2013, Pages 149-162

  Zheng, Bing ^a   Wang, Chunyan ^a   He, Lihong ^a   Xu, Xiaojing ^a   Qu, Jing ^a   Hu, Jun ^a   Zhang, Huanxiang ^a  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

F ACTIN; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE B; SCATTER FACTOR; STRESS ACTIVATED PROTEIN KINASE;

ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CELL MIGRATION; CHEMOTAXIS; CYTOSKELETON; MESENCHYMAL STEM CELL; NERVE REGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT;

ANIMALS; BONE MARROW CELLS; CELL DIFFERENTIATION; CELL MOVEMENT; GENE EXPRESSION REGULATION; HEPATOCYTE GROWTH FACTOR; HUMANS; MESENCHYMAL STROMAL CELLS; MITOGEN-ACTIVATED PROTEIN KINASES; NEURONS; PHOSPHATIDYLINOSITOL 3-KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-MET; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84867179820     PISSN: 00219541     EISSN: 10974652     Source Type: Journal    
DOI: 10.1002/jcp.24114     Document Type: Article

References (66)

1. Alexanian AR, Maiman DJ, Kurpad SN, Gennarelli TA. 2008. In vitro and in vivo characterization of neurally modified mesenchymal stem cells induced by epigenetic modifiers and neural stem cell environment. Stem Cells Dev 17: 1123-1130.
2. Brazelton TR, Rossi FM, Keshet GI, Blau HM. 2000. From marrow to brain: Expression of neuronal phenotypes in adult mice. Science 290: 1775-1779.
3. Chen J, Li Y, Katakowski M, Chen X, Wang L, Lu D, Lu M, Gautam SC, Chopp M. 2003. Intravenous bone marrow stromal cell therapy reduces apoptosis and promotes endogenous cell proliferation after stroke in female rat. J Neurosci Res 73: 778-786.
4. Comoglio PM, Trusolino L. 2002. Invasive growth: From development to metastasis. J Clin Invest 109: 857-862.
5. Corti S, Locatelli F, Papadimitriou D, Strazzer S, Comi GP. 2004. Somatic stem cell research for neural repair: Current evidence and emerging perspectives. J Cell Mol Med 8: 329-337.
6. Cova L, Armentero MT, Zennaro E, Calzarossa C, Bossolasco P, Busca G, Lambertenghi Deliliers G, Polli E, Nappi G, Silani V, Blandini F. 2010. Multiple neurogenic and neurorescue effects of human mesenchymal stem cell after transplantation in an experimental model of Parkinson's disease. Brain Res 1311: 12-27.
7. Crigler L, Robey RC, Asawachaicharn A, Gaupp D, Phinney DG. 2006. Human mesenchymal stem cell subpopulations express a variety of neuro-regulatory molecules and promote neuronal cell survival and neuritogenesis. Exp Neurol 198: 54-64.
8. Delcroix GJ, Jacquart M, Lemaire L, Sindji L, Franconi F, Le Jeune JJ, Montero-Menei CN. 2009. Mesenchymal and neural stem cells labeled with HEDP-coated SPIO nanoparticles: In vitro characterization and migration potential in rat brain. Brain Res 1255: 18-31.
9. Deng W, Obrocka M, Fischer I, Prockop DJ. 2001. In vitro differentiation of human marrow stromal cells into early progenitors of neural cells by conditions that increase intracellular cyclic AMP. Biochem Biophys Res Commun 282: 148-152.
10. Doucette T, Rao G, Yang Y, Gumin J, Shinojima N, Bekele BN, Qiao W, Zhang W, Lang FF. 2011. Mesenchymal stem cells display tumor-specific tropism in an RCAS/Ntv-a glioma model. Neoplasia 13: 716-725.
11. Duan HF, Wu CT, Lu Y, Wang H, Liu HJ, Zhang QW, Jia XX, Lu ZZ, Wang LS. 2004. Sphingosine kinase activation regulates hepatocyte growth factor induced migration of endothelial cells. Exp Cell Res 298: 593-601.
12. Fiedler J, Roderer G, Gunther KP, Brenner RE. 2002. BMP-2, BMP-4, and PDGF-bb stimulate chemotactic migration of primary human mesenchymal progenitor cells. J Cell Biochem 87: 305-312.
13. Fiedler J, Leucht F, Waltenberger J, Dehio C, Brenner RE. 2005. VEGF-A and PlGF-1 stimulate chemotactic migration of human mesenchymal progenitor cells. Biochem Biophys Res Commun 334: 561-568.
14. Forte G, Minieri M, Cossa P, Antenucci D, Sala M, Gnocchi V, Fiaccavento R, Carotenuto F, De Vito P, Baldini PM, Prat M, Di Nardo P. 2006. Hepatocyte growth factor effects on mesenchymal stem cells: Proliferation, migration, and differentiation. Stem Cells 24: 23-33.
15. Gagari E, Rand MK, Tayari L, Vastardis H, Sharma P, Hauschka PV, Damoulis PD. 2006. Expression of stem cell factor and its receptor, c-kit, in human oral mesenchymal cells. Eur J Oral Sci 114: 409-415.
16. Garzotto D, Giacobini P, Crepaldi T, Fasolo A, De Marchis S. 2008. Hepatocyte growth factor regulates migration of olfactory interneuron precursors in the rostral migratory stream through Met-Grb2 coupling. J Neurosci 28: 5901-5909.
17. Giacobini P, Giampietro C, Fioretto M, Maggi R, Cariboni A, Perroteau I, Fasolo A. 2002. Hepatocyte growth factor/scatter factor facilitates migration of GN-11 immortalized LHRH neurons. Endocrinology 143: 3306-3315.
18. Harting MT, Jimenez F, Xue H, Fischer UM, Baumgartner J, Dash PK, Cox CS. 2009. Intravenous mesenchymal stem cell therapy for traumatic brain injury. J Neurosurg 110: 1189-1197.
19. Hu SL, Luo HS, Li JT, Xia YZ, Li L, Zhang LJ, Meng H, Cui GY, Chen Z, Wu N, Lin JK, Zhu G, Feng H. 2010. Functional recovery in acute traumatic spinal cord injury after transplantation of human umbilical cord mesenchymal stem cells. Crit Care Med 38: 2181-2189.
20. Huang C, Jacobson K, Schaller MD. 2004. MAP kinases and cell migration. J Cell Sci 117: 4619-4628.
21. Huttenlocher A. 2005. Cell polarization mechanisms during directed cell migration. Nat Cell Biol 7: 336-337.
22. Isakova IA, Baker K, DuTreil M, Dufour J, Gaupp D, Phinney DG. 2007. Age- and dose-related effects on MSC engraftment levels and anatomical distribution in the central nervous systems of nonhuman primates: Identification of novel MSC subpopulations that respond to guidance cues in brain. Stem Cells 25: 3261-3270.
23. Jendelova P, Herynek V, Urdzikova L, Glogarova K, Kroupova J, Andersson B, Bryja V, Burian M, Hajek M, Sykova E. 2004. Magnetic resonance tracking of transplanted bone marrow and embryonic stem cells labeled by iron oxide nanoparticles in rat brain and spinal cord. J Neurosci Res 76: 232-243.
24. Jin HK, Carter JE, Huntley GW, Schuchman EH. 2002. Intracerebral transplantation of mesenchymal stem cells into acid sphingomyelinase-deficient mice delays the onset of neurological abnormalities and extends their life span. J Clin Invest 109: 1183-1191.
25. Kao AP, Wang KH, Chang CC, Lee JN, Long CY, Chen HS, Tsai CF, Hsieh TH, Tsai EM. 2011. Comparative study of human eutopic and ectopic endometrial mesenchymal stem cells and the development of an in vivo endometriotic invasion model. Fertil Steril 95: 1308-1315, e1301.
26. Kim SM, Lim JY, Park SI, Jeong CH, Oh JH, Jeong M, Oh W, Park SH, Sung YC, Jeun SS. 2008. Gene therapy using TRAIL-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial glioma. Cancer Res 68: 9614-9623.
27. Kitada M, Dezawa M. 2008. Neural repair. Nihon Rinsho 66: 921-925.
28. Kopen GC, Prockop DJ, Phinney DG. 1999. Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains. Proc Natl Acad Sci USA 96: 10711-10716.
29. Lee WJ, Wu LF, Chen WK, Wang CJ, Tseng TH. 2006. Inhibitory effect of luteolin on hepatocyte growth factor/scatter factor-induced HepG2 cell invasion involving both MAPK/ERKs and PI3K-Akt pathways. Chem Biol Interact 160: 123-133.
30. Lepski G, Jannes CE, Strauss B, Marie SK, Nikkhah G. 2010. Survival and neuronal differentiation of mesenchymal stem cells transplanted into the rodent brain are dependent upon microenvironment. Tissue Eng Part A 16: 2769-2782.
31. Li Y, Chen J, Chen XG, Wang L, Gautam SC, Xu YX, Katakowski M, Zhang LJ, Lu M, Janakiraman N, Chopp M. 2002. Human marrow stromal cell therapy for stroke in rat: Neurotrophins and functional recovery. Neurology 59: 514-523.
32. Magavi SS, Leavitt BR, Macklis JD. 2000. Induction of neurogenesis in the neocortex of adult mice. Nature 405: 951-955.
33. Mahmood A, Lu D, Wang L, Chopp M. 2002. Intracerebral transplantation of marrow stromal cells cultured with neurotrophic factors promotes functional recovery in adult rats subjected to traumatic brain injury. J Neurotrauma 19: 1609-1617.
34. Mishima Y, Lotz M. 2008. Chemotaxis of human articular chondrocytes and mesenchymal stem cells. J Orthop Res 26: 1407-1412.
35. Mortimer D, Fothergill T, Pujic Z, Richards LJ, Goodhill GJ. 2008. Growth cone chemotaxis. Trends Neurosci 31: 90-98.
36. Muller M, Morotti A, Ponzetto C. 2002. Activation of NF-kappaB is essential for hepatocyte growth factor-mediated proliferation and tubulogenesis. Mol Cell Biol 22: 1060-1072.
37. Neuss S, Becher E, Woltje M, Tietze L, Jahnen-Dechent W. 2004. Functional expression of HGF and HGF receptor/c-met in adult human mesenchymal stem cells suggests a role in cell mobilization, tissue repair, and wound healing. Stem Cells 22: 405-414.
38. Pisati F, Bossolasco P, Meregalli M, Cova L, Belicchi M, Gavina M, Marchesi C, Calzarossa C, Soligo D, Lambertenghi-Deliliers G, Bresolin N, Silani V, Torrente Y, Polli E. 2007. Induction of neurotrophin expression via human adult mesenchymal stem cells: Implication for cell therapy in neurodegenerative diseases. Cell Transplant 16: 41-55.
39. Pittenger MF, Mackay AM, Beck SC, Jaiswal RK, Douglas R, Mosca JD, Moorman MA, Simonetti DW, Craig S, Marshak DR. 1999. Multilineage potential of adult human mesenchymal stem cells. Science 284: 143-147.
40. Ponzetto C, Bardelli A, Zhen Z, Maina F, dalla Zonca P, Giordano S, Graziani A, Panayotou G, Comoglio PM. 1994. A multifunctional docking site mediates signaling and transformation by the hepatocyte growth factor/scatter factor receptor family. Cell 77: 261-271.
41. Rakic P. 2002. Adult neurogenesis in mammals: An identity crisis. J Neurosci 22: 614-618.
42. Rosova I, Dao M, Capoccia B, Link D, Nolta JA. 2008. Hypoxic preconditioning results in increased motility and improved therapeutic potential of human mesenchymal stem cells. Stem Cells 26: 2173-2182.
43. Ryu CH, Park SA, Kim SM, Lim JY, Jeong CH, Jun JA, Oh JH, Park SH, Oh WI, Jeun SS. 2010. Migration of human umbilical cord blood mesenchymal stem cells mediated by stromal cell-derived factor-1/CXCR4 axis via Akt, ERK, and p38 signal transduction pathways. Biochem Biophys Res Commun 398: 105-110.
44. Sanchez-Ramos JR. 2002. Neural cells derived from adult bone marrow and umbilical cord blood. J Neurosci Res 69: 880-893.
45. Segarra J, Balenci L, Drenth T, Maina F, Lamballe F. 2006. Combined signaling through ERK, PI3K/AKT, and RAC1/p38 is required for met-triggered cortical neuron migration. J Biol Chem 281: 4771-4778.
46. Serrador JM, Nieto M, Sanchez-Madrid F. 1999. Cytoskeletal rearrangement during migration and activation of T lymphocytes. Trends Cell Biol 9: 228-233.
47. Shyu WC, Chen CP, Lin SZ, Lee YJ, Li H. 2007. Efficient tracking of non-iron-labeled mesenchymal stem cells with serial MRI in chronic stroke rats. Stroke 38: 367-374.
48. Son BR, Marquez-Curtis LA, Kucia M, Wysoczynski M, Turner AR, Ratajczak J, Ratajczak MZ, Janowska-Wieczorek A. 2006. Migration of bone marrow and cord blood mesenchymal stem cells in vitro is regulated by stromal-derived factor-1-CXCR4 and hepatocyte growth factor-c-met axes and involves matrix metalloproteinases. Stem Cells 24: 1254-1264.
49. Sordi V, Malosio ML, Marchesi F, Mercalli A, Melzi R, Giordano T, Belmonte N, Ferrari G, Leone BE, Bertuzzi F, Zerbini G, Allavena P, Bonifacio E, Piemonti L. 2005. Bone marrow mesenchymal stem cells express a restricted set of functionally active chemokine receptors capable of promoting migration to pancreatic islets. Blood 106: 419-427.
50. Stephens P, Hiscox S, Cook H, Jiang WG, Zhiquiang W, Thomas DW. 2001. Phenotypic variation in the production of bioactive hepatocyte growth factor/scatter factor by oral mucosal and skin fibroblasts. Wound Repair Regen 9: 34-43.
51. Sykova E, Jendelova P. 2006. Magnetic resonance tracking of transplanted stem cells in rat brain and spinal cord. Neurodegener Dis 3: 62-67.
52. Tang J, Wang J, Kong X, Yang J, Guo L, Zheng F, Zhang L, Huang Y, Wan Y. 2009. Vascular endothelial growth factor promotes cardiac stem cell migration via the PI3K/Akt pathway. Exp Cell Res 315: 3521-3531.
53. Temple S, Alvarez-Buylla A. 1999. Stem cells in the adult mammalian central nervous system. Curr Opin Neurobiol 9: 135-141.
54. Tfilin M, Sudai E, Merenlender A, Gispan I, Yadid G, Turgeman G. 2010. Mesenchymal stem cells increase hippocampal neurogenesis and counteract depressive-like behavior. Mol Psychiatry 15: 1164-1175.
55. van Haaften T, Byrne R, Bonnet S, Rochefort GY, Akabutu J, Bouchentouf M, Rey-Parra GJ, Galipeau J, Haromy A, Eaton F, Chen M, Hashimoto K, Abley D, Korbutt G, Archer SL, Thebaud B. 2009. Airway delivery of mesenchymal stem cells prevents arrested alveolar growth in neonatal lung injury in rats. Am J Respir Crit Care Med 180: 1131-1142.
56. Vande Woude GF, Jeffers M, Cortner J, Alvord G, Tsarfaty I, Resau J. 1997. Met-HGF/SF: Tumorigenesis, invasion and metastasis. CIBA Found Symp 212: 119-130, discussion 130-112, 148-154.
57. Veit C, Genze F, Menke A, Hoeffert S, Gress TM, Gierschik P, Giehl K. 2004. Activation of phosphatidylinositol 3-kinase and extracellular signal-regulated kinase is required for glial cell line-derived neurotrophic factor-induced migration and invasion of pancreatic carcinoma cells. Cancer Res 64: 5291-5300.
58. Wang JF, Park IW, Groopman JE. 2000. Stromal cell-derived factor-1alpha stimulates tyrosine phosphorylation of multiple focal adhesion proteins and induces migration of hematopoietic progenitor cells: Roles of phosphoinositide-3 kinase and protein kinase C. Blood 95: 2505-2513.
59. Wang L, Li Y, Chen X, Chen J, Gautam SC, Xu Y, Chopp M. 2002. MCP-1, MIP-1, IL-8 and ischemic cerebral tissue enhance human bone marrow stromal cell migration in interface culture. Hematology 7: 113-117.
60. Woodbury D, Schwarz EJ, Prockop DJ, Black IB. 2000. Adult rat and human bone marrow stromal cells differentiate into neurons. J Neurosci Res 61: 364-370.
61. Wu GD, Nolta JA, Jin YS, Barr ML, Yu H, Starnes VA, Cramer DV. 2003. Migration of mesenchymal stem cells to heart allografts during chronic rejection. Transplantation 75: 679-685.
62. Xu F, Shi J, Yu B, Ni W, Wu X, Gu Z. 2010. Chemokines mediate mesenchymal stem cell migration toward gliomas in vitro. Oncol Rep 23: 1561-1567.
63. Yang M, Wei X, Li J, Heine LA, Rosenwasser R, Iacovitti L. 2010. Changes in host blood factors and brain glia accompanying the functional recovery after systemic administration of bone marrow stem cells in ischemic stroke rats. Cell Transplant 19: 1073-1084.
64. Zhao Z, Watt C, Karystinou A, Roelofs AJ, McCaig CD, Gibson IR, De Bari C. 2011. Directed migration of human bone marrow mesenchymal stem cells in a physiological direct current electric field. Eur Cell Mater 22: 344-358.
65. Zicha D, Dunn GA, Brown AF. 1991. A new direct-viewing chemotaxis chamber. J Cell Sci 99: 769-775.
66. Zou C, Song G, Luo Q, Yuan L, Yang L. 2011. Mesenchymal stem cells require integrin beta1 for directed migration induced by osteopontin in vitro. In Vitro Cell Dev Biol Anim 47: 241-250.