Long-term maintenance of mouse embryonic stem cell pluripotency by manipulating integrin signaling within 3D scaffolds without active Stat3

Biomaterials

Volumn 33, Issue 35, 2012, Pages 8934-8942

  Lee, Seung Tae ^a,b   Yun, Jung Im ^a,b   van der Vlies, Andre J ^a   Kontos, Stephan ^a   Jang, Mi ^c   Gong, Seung Pyo ^d   Kim, Dae Yong ^c   Lim, Jeong M ^c   Hubbell, Jeffrey A ^a  

^a EPFL   (Switzerland)

^b Kangwon National University   (South Korea)

^c Seoul National University   (South Korea)

^d Pukyong National University   (South Korea)

Author keywords

Embryonic stem cell; Hydrogel; Integrin; Niche; Self renewal; Signaling

Indexed keywords

3-D ENVIRONMENTS; 3D SCAFFOLDS; CELL COLONIES; EMBRYONIC STEM CELLS; ES CELLS; HYDROGEL SCAFFOLDS; INTEGRINS; LEUKEMIA INHIBITORY FACTORS; MICROENVIRONMENTS; MOUSE EMBRYONIC STEM CELLS; NICHE; PLURIPOTENCY; SELF-RENEWAL; SPHERICAL MORPHOLOGIES;

BIOMIMETICS; CYTOLOGY; GLYCOPROTEINS; HYDROGELS; MAMMALS; SIGNALING; STEM CELLS; THREE DIMENSIONAL COMPUTER GRAPHICS;

SCAFFOLDS (BIOLOGY);

ALPHAVBETA5 INTEGRIN; INTEGRIN; INTEGRIN ALPHA9BETA1; LEUKEMIA INHIBITORY FACTOR; MACROGOL; PROTEIN KINASE B; SMAD1 PROTEIN; SMAD5 PROTEIN; SMAD8 PROTEIN; STAT3 PROTEIN; TISSUE SCAFFOLD; UNCLASSIFIED DRUG; VERY LATE ACTIVATION ANTIGEN 5; VERY LATE ACTIVATION ANTIGEN 6;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BIOMIMETICS; CELL ACTIVITY; CELL CULTURE; CELL FATE; CELL RENEWAL; CELL STIMULATION; CELL STRUCTURE; CONTROLLED STUDY; EMBRYONIC STEM CELL; HYDROGEL; MOUSE; NONHUMAN; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STEM CELL NICHE; STEM CELL TRANSPLANTATION; TERATOMA;

ANIMALS; BLOTTING, WESTERN; CELL DIFFERENTIATION; CELL PROLIFERATION; EMBRYONIC STEM CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENE EXPRESSION REGULATION; HYDROGELS; INTEGRINS; LEUKEMIA INHIBITORY FACTOR; MICE; PLURIPOTENT STEM CELLS; REAL-TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STAT3 TRANSCRIPTION FACTOR; TISSUE SCAFFOLDS;

EID: 84867142930     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2012.08.062     Document Type: Article

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